Medical College of Wisconsin
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William E. Cullinan PhD

Adjunct Associate Professor

Institution: Medical College of Wisconsin
Department: Neurosurgery
Program: Adult

Member of the Neuroscience Research Center

Publications (44)

  • Primary blast traumatic brain injury in the rat: relating diffusion tensor imaging and behavior. (Budde MD, Shah A, McCrea M, Cullinan WE, Pintar FA, Stemper BD) Front Neurol 2013;4:154 PMID: 24133481 PMCID: PMC3796287 10/18/2013    
  • Central stress-integrative circuits: forebrain glutamatergic and GABAergic projections to the dorsomedial hypothalamus, medial preoptic area, and bed nucleus of the stria terminalis. (Myers B, Mark Dolgas C, Kasckow J, Cullinan WE, Herman JP) Brain Struct Funct 2014 Jul;219(4):1287-303 PMID: 23661182 PMCID: PMC3778169 SCOPUS ID: 2-s2.0-84904353796 05/11/2013       88 Citations
  • Brainstem origins of glutamatergic innervation of the rat hypothalamic paraventricular nucleus. (Ziegler DR, Edwards MR, Ulrich-Lai YM, Herman JP, Cullinan WE) J Comp Neurol 2012 Aug 01;520(11):2369-94 PMID: 22247025 PMCID: PMC4440805 SCOPUS ID: 2-s2.0-84860908768 01/17/2012       36 Citations
  • Forebrain origins of glutamatergic innervation to the rat paraventricular nucleus of the hypothalamus: differential inputs to the anterior versus posterior subregions. (Ulrich-Lai YM, Jones KR, Ziegler DR, Cullinan WE, Herman JP) J Comp Neurol 2011 May 01;519(7):1301-19 PMID: 21452198 PMCID: PMC3893028 SCOPUS ID: 2-s2.0-79953152521 04/01/2011       57 Citations
  • Effect of animal facility construction on basal hypothalamic-pituitary-adrenal and renin-aldosterone activity in the rat. (Raff H, Bruder ED, Cullinan WE, Ziegler DR, Cohen EP) Endocrinology 2011 Apr;152(4):1218-21 PMID: 21248141 PMCID: PMC3060631 SCOPUS ID: 2-s2.0-79953219058 01/21/2011       19 Citations
  • Effect of high-dose total body irradiation on ACTH, corticosterone, and catecholamines in the rat. (Cohen EP, Bruder ED, Cullinan WE, Ziegler D, Raff H) Transl Res 2011 Jan;157(1):38-47 PMID: 21146149 PMCID: PMC3053012 SCOPUS ID: 2-s2.0-78649993695 12/15/2010       6 Citations
  • Functional role of local GABAergic influences on the HPA axis. (Cullinan WE, Ziegler DR, Herman JP) Brain Struct Funct 2008 Sep;213(1-2):63-72 PMID: 18696110 SCOPUS ID: 2-s2.0-50249092178 08/13/2008       173 Citations
  • Augmented hypothalamic corticotrophin-releasing hormone mRNA and corticosterone responses to stress in adult rats exposed to perinatal hypoxia. (Raff H, Jacobson L, Cullinan WE) J Neuroendocrinol 2007 Nov;19(11):907-12 PMID: 17927669 PMCID: PMC2030994 SCOPUS ID: 2-s2.0-35048852641 10/12/2007       31 Citations
  • Daily cocaine self-administration under long-access conditions augments restraint-induced increases in plasma corticosterone and impairs glucocorticoid receptor-mediated negative feedback in rats. (Mantsch JR, Cullinan WE, Tang LC, Baker DA, Katz ES, Hoks MA, Ziegler DR) Brain Res 2007 Sep 05;1167:101-11 PMID: 17689506 PMCID: PMC2121305 SCOPUS ID: 2-s2.0-34548133391 08/11/2007       45 Citations
  • Restraint-induced corticosterone secretion and hypothalamic CRH mRNA expression are augmented during acute withdrawal from chronic cocaine administration. (Mantsch JR, Taves S, Khan T, Katz ES, Sajan T, Tang LC, Cullinan WE, Ziegler DR) Neurosci Lett 2007 Mar 30;415(3):269-73 PMID: 17293045 PMCID: PMC1978484 SCOPUS ID: 2-s2.0-33947162167 02/13/2007       27 Citations
  • Organization and regulation of paraventricular nucleus glutamate signaling systems: N-methyl-D-aspartate receptors. (Ziegler DR, Cullinan WE, Herman JP) J Comp Neurol 2005 Mar 28;484(1):43-56 PMID: 15717303 SCOPUS ID: 2-s2.0-14644391614 02/18/2005       69 Citations
  • Endocannabinoid signaling negatively modulates stress-induced activation of the hypothalamic-pituitary-adrenal axis. (Patel S, Roelke CT, Rademacher DJ, Cullinan WE, Hillard CJ) Endocrinology 2004 Dec;145(12):5431-8 PMID: 15331569 SCOPUS ID: 2-s2.0-9444277292 08/28/2004       383 Citations
  • Central mechanisms of stress integration: hierarchical circuitry controlling hypothalamo-pituitary-adrenocortical responsiveness. (Herman JP, Figueiredo H, Mueller NK, Ulrich-Lai Y, Ostrander MM, Choi DC, Cullinan WE) Front Neuroendocrinol 2003 Jul;24(3):151-80 PMID: 14596810 SCOPUS ID: 2-s2.0-0242352373 11/05/2003       1219 Citations
  • Elevated corticosterone and inhibition of ACTH responses to CRH and ether in the neonatal rat: effect of hypoxia from birth. (Raff H, Jacobson L, Cullinan WE) Am J Physiol Regul Integr Comp Physiol 2003 Nov;285(5):R1224-30 PMID: 12855418 SCOPUS ID: 2-s2.0-0142249309 07/12/2003       28 Citations
  • Abused drugs modulate RGS4 mRNA levels in rat brain: comparison between acute drug treatment and a drug challenge after chronic treatment. (Bishop GB, Cullinan WE, Curran E, Gutstein HB) Neurobiol Dis 2002 Aug;10(3):334-43 PMID: 12270694 SCOPUS ID: 2-s2.0-0036403890 09/25/2002       55 Citations
  • Role of the paraventricular nucleus microenvironment in stress integration. (Herman JP, Cullinan WE, Ziegler DR, Tasker JG) Eur J Neurosci 2002 Aug;16(3):381-5 PMID: 12193178 SCOPUS ID: 2-s2.0-0036460384 08/24/2002       138 Citations
  • Distribution of vesicular glutamate transporter mRNA in rat hypothalamus. (Ziegler DR, Cullinan WE, Herman JP) J Comp Neurol 2002 Jul 01;448(3):217-29 PMID: 12115705 SCOPUS ID: 2-s2.0-0036642970 07/13/2002       196 Citations
  • Local circuit regulation of paraventricular nucleus stress integration: glutamate-GABA connections. (Herman JP, Tasker JG, Ziegler DR, Cullinan WE) Pharmacol Biochem Behav 2002 Mar;71(3):457-68 PMID: 11830180 SCOPUS ID: 2-s2.0-0036159865 02/07/2002       225 Citations
  • Increased mRNA expression for the alpha(1) subunit of the GABA(A) receptor following nitrous oxide exposure in mice. (Johanek LM, Cullinan WE, Vaughn LK) Brain Res Mol Brain Res 2001 Apr 18;89(1-2):41-9 PMID: 11311974 SCOPUS ID: 2-s2.0-0035906265 04/20/2001       5 Citations
  • Chronic stress regulates levels of mRNA transcripts encoding beta subunits of the GABA(A) receptor in the rat stress axis. (Cullinan WE, Wolfe TJ) Brain Res 2000 Dec 22;887(1):118-24 PMID: 11134596 SCOPUS ID: 2-s2.0-0034704281 01/03/2001       88 Citations
  • GABA(A) receptor subunit expression within hypophysiotropic CRH neurons: a dual hybridization histochemical study. (Cullinan WE) J Comp Neurol 2000 Apr 10;419(3):344-51 PMID: 10723009 SCOPUS ID: 2-s2.0-0034007564 03/21/2000       109 Citations
  • Region-specific regulation of glutamic acid decarboxylase (GAD) mRNA expression in central stress circuits. (Bowers G, Cullinan WE, Herman JP) J Neurosci 1998 Aug 01;18(15):5938-47 PMID: 9671680 PMCID: PMC6793042 SCOPUS ID: 2-s2.0-17344363638 07/22/1998       210 Citations
  • Cortical input to the basal forebrain. (Zaborszky L, Gaykema RP, Swanson DJ, Cullinan WE) Neuroscience 1997 Aug;79(4):1051-78 PMID: 9219967 SCOPUS ID: 2-s2.0-0030738056 08/01/1997       169 Citations
  • Elicitation and reduction of fear: behavioural and neuroendocrine indices and brain induction of the immediate-early gene c-fos. (Campeau S, Falls WA, Cullinan WE, Helmreich DL, Davis M, Watson SJ) Neuroscience 1997 Jun;78(4):1087-104 PMID: 9174076 SCOPUS ID: 2-s2.0-0030983258 06/01/1997       214 Citations
  • Neurocircuitry of stress: central control of the hypothalamo-pituitary-adrenocortical axis. (Herman JP, Cullinan WE) Trends Neurosci 1997 Feb;20(2):78-84 PMID: 9023876 SCOPUS ID: 2-s2.0-0031015517 02/01/1997       1804 Citations
  • Direct catecholaminergic-cholinergic interactions in the basal forebrain. I. Dopamine-beta-hydroxylase- and tyrosine hydroxylase input to cholinergic neurons. (Zaborszky L, Cullinan WE) J Comp Neurol 1996 Oct 28;374(4):535-54 PMID: 8910734 SCOPUS ID: 2-s2.0-0029987394 10/28/1996       83 Citations
  • Fos expression in forebrain afferents to the hypothalamic paraventricular nucleus following swim stress. (Cullinan WE, Helmreich DL, Watson SJ) J Comp Neurol 1996 Apr 22;368(1):88-99 PMID: 8725295 SCOPUS ID: 2-s2.0-0030006054 04/22/1996       160 Citations
  • The effect of adrenalectomy on stress-induced c-fos mRNA expression in the rat brain. (Helmreich DL, Cullinan WE, Watson SJ) Brain Res 1996 Jan 08;706(1):137-44 PMID: 8720501 SCOPUS ID: 2-s2.0-0030033964 01/08/1996       42 Citations
  • Neuronal circuit regulation of the hypothalamo-pituitary-adrenocortical stress axis. (Herman JP, Prewitt CM, Cullinan WE) Crit Rev Neurobiol 1996;10(3-4):371-94 PMID: 8978987 SCOPUS ID: 2-s2.0-0030463572 01/01/1996       297 Citations
  • Contribution of the ventral subiculum to inhibitory regulation of the hypothalamo-pituitary-adrenocortical axis. (Herman JP, Cullinan WE, Morano MI, Akil H, Watson SJ) J Neuroendocrinol 1995 Jun;7(6):475-82 PMID: 7550295 SCOPUS ID: 2-s2.0-0029143974 06/01/1995       157 Citations
  • Pattern and time course of immediate early gene expression in rat brain following acute stress. (Cullinan WE, Herman JP, Battaglia DF, Akil H, Watson SJ) Neuroscience 1995 Jan;64(2):477-505 PMID: 7700534 SCOPUS ID: 2-s2.0-0028894469 01/01/1995       871 Citations
  • Involvement of the bed nucleus of the stria terminalis in tonic regulation of paraventricular hypothalamic CRH and AVP mRNA expression. (Herman JP, Cullinan WE, Watson SJ) J Neuroendocrinol 1994 Aug;6(4):433-42 PMID: 7987374 SCOPUS ID: 2-s2.0-0028133308 08/01/1994       199 Citations
  • Ventral subicular interaction with the hypothalamic paraventricular nucleus: evidence for a relay in the bed nucleus of the stria terminalis. (Cullinan WE, Herman JP, Watson SJ) J Comp Neurol 1993 Jun 01;332(1):1-20 PMID: 7685778 SCOPUS ID: 2-s2.0-0027232779 06/01/1993       416 Citations
  • Gene expression of prohormone and proprotein convertases in the rat CNS: a comparative in situ hybridization analysis. (Schäfer MK, Day R, Cullinan WE, Chrétien M, Seidah NG, Watson SJ) J Neurosci 1993 Mar;13(3):1258-79 PMID: 8441010 PMCID: PMC6576608 SCOPUS ID: 2-s2.0-0027404880 03/01/1993       210 Citations
  • Region specific expression of furin mRNA in the rat brain. (Day R, Schafer MK, Cullinan WE, Watson SJ, Chrétien M, Seidah NG) Neurosci Lett 1993 Jan 04;149(1):27-30 PMID: 8469374 SCOPUS ID: 2-s2.0-0027466131 01/04/1993       52 Citations
  • Catecholaminergic-cholinergic interaction in the basal forebrain. (Záborszky L, Cullinan WE, Luine VN) Prog Brain Res 1993;98:31-49 PMID: 7902593 SCOPUS ID: 2-s2.0-0027515384 01/01/1993       67 Citations
  • Selective forebrain fiber tract lesions implicate ventral hippocampal structures in tonic regulation of paraventricular nucleus corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) mRNA expression. (Herman JP, Cullinan WE, Young EA, Akil H, Watson SJ) Brain Res 1992 Oct 02;592(1-2):228-38 PMID: 1333341 SCOPUS ID: 2-s2.0-0026731199 10/02/1992       120 Citations
  • Projections from the nucleus accumbens to cholinergic neurons of the ventral pallidum: a correlated light and electron microscopic double-immunolabeling study in rat. (Záborszky L, Cullinan WE) Brain Res 1992 Jan 20;570(1-2):92-101 PMID: 1617433 SCOPUS ID: 2-s2.0-0026571262 01/20/1992       116 Citations
  • Anatomical studies of neuropeptide precursor processing enzymes. (Watson SJ, Cullinan WE, Schafer MK, Day R, Chretien M, Seidah NG) Clin Neuropharmacol 1992;15 Suppl 1 Pt A:315A-316A PMID: 1498853 SCOPUS ID: 2-s2.0-18744419261 01/01/1992    
  • Organization of ascending hypothalamic projections to the rostral forebrain with special reference to the innervation of cholinergic projection neurons. (Cullinan WE, Záborszky L) J Comp Neurol 1991 Apr 22;306(4):631-67 PMID: 2071698 SCOPUS ID: 2-s2.0-0025845446 04/22/1991       96 Citations
  • Afferents to basal forebrain cholinergic projection neurons: an update. (Záborszky L, Cullinan WE, Braun A) Adv Exp Med Biol 1991;295:43-100 PMID: 1776580 SCOPUS ID: 2-s2.0-0026349880 01/01/1991       120 Citations
  • Neuroanatomical and functional studies of peptide precursor-processing enzymes. (Cullinan WE, Day NC, Schäfer MK, Day R, Seidah NG, Chrétien M, Akil H, Watson SJ) Enzyme 1991;45(5-6):285-300 PMID: 1843282 SCOPUS ID: 2-s2.0-0026351028 01/01/1991       18 Citations
  • Hypothalamic axons terminate on forebrain cholinergic neurons: an ultrastructural double-labeling study using PHA-L tracing and ChAT immunocytochemistry. (Zaborszky L, Cullinan WE) Brain Res 1989 Feb 06;479(1):177-84 PMID: 2924147 SCOPUS ID: 2-s2.0-0024496309 02/06/1989       54 Citations
  • Unilateral odor deprivation: effects on the development of staining for olfactory bulb succinate dehydrogenase. (Cullinan WE, Brunjes PC) Brain Res 1987 Sep;432(1):35-42 PMID: 2820549 SCOPUS ID: 2-s2.0-0023205321 09/01/1987       36 Citations
  • Last update: 06/15/2021