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Cellular signalling: STIMulating calcium entry. Curr Biol 2005 Jul 12;15(13):R493-5 PMID: 16005278

Abstract

The molecular identity of the signal coupling intracellular Ca(2+) store depletion to the activation of Ca(2+) entry has long resisted exposure. Two recent studies independently implicate the STIM protein family as essential components in this coupling. These data provide new impetus to resolve how store Ca(2+) content is sensed and communicated to store-operated Ca(2+) channels at the cell surface.

Author List

Marchant JS

Author

Jonathan S. Marchant PhD Chair, Professor in the Cell Biology, Neurobiology and Anatomy department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Biological Transport, Active
Calcium
Calcium Channels
Endoplasmic Reticulum
Humans
Ion Transport
Membrane Proteins
Models, Biological
Neoplasm Proteins
RNA Interference
Signal Transduction



View this publication's entry at the Pubmed website PMID: 16005278
jenkins-FCD Prod-130 96200611f8481f0aa4f84230b11dd74d063847a3