Medical College of Wisconsin
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IgM nephropathy - Successful treatment with rituximab. Saudi J Kidney Dis Transpl 2019;30(1):235-238

Date

02/26/2019

Pubmed ID

30804288

DOI

10.4103/1319-2442.252917

Scopus ID

2-s2.0-85062165806 (requires institutional sign-in at Scopus site)   4 Citations

Abstract

Immunoglobulin M nephropathy (IgMN) is a primary glomerulonephritis which is characterized by variable degrees of morphological features ranging from minimal glomerular involvement to segmental or global sclerosis. No specific treatment is known to date for this disease because of uncertainties in etiopathogenesis. The mainstay treatment for this disease has been corticosteroids, which has varying degrees of resistance ranging from 0% to 50%. We present the case of a 59-year-old Caucasian male who was referred to the outpatient nephrology clinic for the evaluation of proteinuria and was diagnosed with IgMN. We successfully treated the patient with rituximab with resolution of his proteinuria.

Author List

Ahmed FA, El-Meanawy A

Author

Ashraf El-Meanawy MD, PhD Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Glomerulonephritis
Humans
Immunoglobulin M
Immunologic Factors
Male
Middle Aged
Proteinuria
Rituximab