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Postdischarge pain, functional limitations and impact on caregivers of children with sickle cell disease treated for painful events. Br J Haematol 2009 Mar;144(5):782-8

Date

12/06/2008

Pubmed ID

19055663

Pubmed Central ID

PMC3118502

DOI

10.1111/j.1365-2141.2008.07512.x

Scopus ID

2-s2.0-58849088040   32 Citations

Abstract

This study aimed to describe the outcomes of children with sickle cell disease (SCD) after discharge from medical care for vaso-occlusive painful events and to test the hypothesis that older age, longer length of hospital stay, and a history of frequent vaso-occlusive painful events will be associated with poor outcomes. Children aged 2-18 years with SCD treated in the emergency department or inpatient unit for a painful event were contacted after discharge to assess: days of pain, days of functional limitations for the child, and days of work/school absenteeism for the caregiver. Descriptive statistics were applied and multivariate logistic regression examined the association between the predictors and outcomes. Fifty-eight children were enrolled (mean age 10.8 +/- 4.8 years, 53.5% female). Postdischarge, 46.5% of children reported three or more days of pain, 54.3% had two or more days of functional limitations, and 24.3% of caregivers missed two or more days of work/school. Children with three or more prior painful events had increased odds of a poor outcome postdischarge (OR 1.79; 95% CI = 1.026, 3.096). In conclusion, acute vaso-occlusive painful events impact the lives of children with SCD and their caregivers, even after discharge to home.

Author List

Brandow AM, Brousseau DC, Panepinto JA

Authors

Amanda Brandow DO Professor in the Pediatrics department at Medical College of Wisconsin
David Brousseau MD Chief, Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Absenteeism
Activities of Daily Living
Adolescent
Age Factors
Anemia, Sickle Cell
Antisickling Agents
Caregivers
Child
Cost of Illness
Female
Genotype
Humans
Length of Stay
Logistic Models
Male
Pain
Patient Discharge
Prospective Studies
Statistics, Nonparametric
Treatment Outcome