Amanda Brandow DO
Research Experience
Pain in Sickle Cell DiseaseClinical Expertise
HematologySickle Cell DiseasePublications (57)
Gut microbiota and metabolites drive chronic sickle cell disease pain. (Sadler KE, Atkinson SN, Ehlers VL, Waltz TB, Hayward M, Rodríguez García DM, Salzman NH, Stucky CL, Brandow AM) bioRxiv 2023 Apr 28 PMID: 37163080 PMCID: PMC10168372 05/10/2023 Preliminary construct validity of patient-reported outcomes to assess chronic pain in adults with sickle cell disease. (Mucalo L, Field JJ, Highland J, Khan H, Hankins JS, Singh A, Brandow AM) Blood Adv 2023 Jul 25;7(14):3658-3665 PMID: 37058480 PMCID: PMC10365933 SCOPUS ID: 2-s2.0-85183192690 04/15/2023 Sickle cell disease patient plasma sensitizes iPSC-derived sensory neurons from sickle cell disease patients. (Allison RL, Burand A, Torres DN, Brandow AM, Stucky CL, Ebert AD) bioRxiv 2023 Jan 10 PMID: 36711992 PMCID: PMC9882050 01/31/2023 Surveillance for the Rare Condition of Sickle Cell Disease in Wisconsin. (Singh A, Dasgupta M, Retherford D, Baker M, Hulihan M, Brandow AM) WMJ 2022 Dec;121(4):297-300 PMID: 36637841 PMCID: PMC10026077 SCOPUS ID: 2-s2.0-85146364141 01/14/2023 1 CitationA perspective on the sickle cell disease international COVID-19 registry. (Mucalo L, Brandow AM, Singh A) Best Pract Res Clin Haematol 2022 Sep;35(3):101385 PMID: 36494148 PMCID: PMC9509018 SCOPUS ID: 2-s2.0-85140073334 12/10/2022 Chronic Pain: Prevalence and Management. (Carroll CP, Brandow AM) Hematol Oncol Clin North Am 2022 Dec;36(6):1151-1165 PMID: 36400536 SCOPUS ID: 2-s2.0-85141978813 11/19/2022 3 CitationsCOVID-19 and venous thromboembolism risk in patients with sickle cell disease. (Singh A, Brandow AM, Wun T, Shet AS) Blood Adv 2022 Aug 09;6(15):4408-4412 PMID: 35763429 PMCID: PMC9239700 SCOPUS ID: 2-s2.0-85135470847 06/29/2022 4 CitationsWeb Exclusive. Annals for Hospitalists Inpatient Notes - Clinical Pearls-Acute Pain Episodes in Sickle Cell Disease. (Strouse JJ, Brandow AM) Ann Intern Med 2022 Mar;175(3):HO2-HO3 PMID: 35286823 SCOPUS ID: 2-s2.0-85126699842 03/15/2022 Advances in the diagnosis and treatment of sickle cell disease. (Brandow AM, Liem RI) J Hematol Oncol 2022 Mar 03;15(1):20 PMID: 35241123 PMCID: PMC8895633 SCOPUS ID: 2-s2.0-85125690529 03/05/2022 46 CitationsNon-crisis related pain occurs in adult patients with sickle cell disease despite chronic red blood cell exchange transfusion therapy. (Curtis SA, Raisa BM, Roberts JD, Hendrickson JE, Starrels J, Lesley D, Michelle D, Daniel Z, Brandow AM) Transfus Apher Sci 2022 Apr;61(2):103304 PMID: 34782244 PMCID: PMC9838733 SCOPUS ID: 2-s2.0-85119079115 11/17/2021 1 CitationA polygenic score for acute vaso-occlusive pain in pediatric sickle cell disease. (Rampersaud E, Kang G, Palmer LE, Rashkin SR, Wang S, Bi W, Alberts NM, Anghelescu D, Barton M, Birch K, Boulos N, Brandow AM, Brooke RJ, Chang TC, Chen W, Cheng Y, Ding J, Easton J, Hodges JR, Kanne CK, Levy S, Mulder H, Patel AP, Puri L, Rosencrance C, Rusch M, Sapkota Y, Sioson E, Sharma A, Tang X, Thrasher A, Wang W, Yao Y, Yasui Y, Yergeau D, Hankins JS, Sheehan VA, Downing JR, Estepp JH, Zhang J, DeBaun M, Wu G, Weiss MJ) Blood Adv 2021 Jul 27;5(14):2839-2851 PMID: 34283174 PMCID: PMC8341359 SCOPUS ID: 2-s2.0-85111179186 07/21/2021 10 CitationsComorbidities are risk factors for hospitalization and serious COVID-19 illness in children and adults with sickle cell disease. (Mucalo L, Brandow AM, Dasgupta M, Mason SF, Simpson PM, Singh A, Taylor BW, Woods KJ, Yusuf FI, Panepinto JA) Blood Adv 2021 Jul 13;5(13):2717-2724 PMID: 34196678 PMCID: PMC8248962 SCOPUS ID: 2-s2.0-85110158013 07/02/2021 33 CitationsCOVID-19 in individuals with sickle cell disease/trait compared with other Black individuals. (Singh A, Brandow AM, Panepinto JA) Blood Adv 2021 Apr 13;5(7):1915-1921 PMID: 33792626 PMCID: PMC8015795 SCOPUS ID: 2-s2.0-85105201375 04/02/2021 47 CitationsRecommendation to reality: Closing the transcranial Doppler screening gap for children with sickle cell anemia. (Singh A, Danda V, Van Swol L, Scott JP, Brandow AM, Panepinto JA) Pediatr Blood Cancer 2021 Feb;68(2):e28831 PMID: 33283465 SCOPUS ID: 2-s2.0-85096913257 12/08/2020 4 CitationsNeuropathic pain in sickle cell disease: measurement and management. (Glaros A, Brandow AM) Hematology Am Soc Hematol Educ Program 2020 Dec 04;2020(1):553-561 PMID: 33275730 PMCID: PMC7727515 SCOPUS ID: 2-s2.0-85097311176 12/05/2020 4 CitationsNeuropathic pain is associated with poor health-related quality of life in adolescents with sickle cell disease: A preliminary report. (Román ME, Highland J, Retherford D, Pan AY, Panepinto JA, Brandow AM) Pediatr Blood Cancer 2020 Dec;67(12):e28698 PMID: 33034107 SCOPUS ID: 2-s2.0-85092201457 10/10/2020 9 CitationsDaily Cannabis Users with Sickle Cell Disease Show Fewer Admissions than Others with Similar Pain Complaints. (Curtis SA, Brandow AM, DeVeaux M, Zeltermam D, Devine L, Roberts JD) Cannabis Cannabinoid Res 2020;5(3):255-262 PMID: 32923662 PMCID: PMC7480712 SCOPUS ID: 2-s2.0-85090352871 09/15/2020 12 CitationsAmerican Society of Hematology 2020 guidelines for sickle cell disease: management of acute and chronic pain. (Brandow AM, Carroll CP, Creary S, Edwards-Elliott R, Glassberg J, Hurley RW, Kutlar A, Seisa M, Stinson J, Strouse JJ, Yusuf F, Zempsky W, Lang E) Blood Adv 2020 Jun 23;4(12):2656-2701 PMID: 32559294 PMCID: PMC7322963 SCOPUS ID: 2-s2.0-85086768915 06/20/2020 162 CitationsEnd points for sickle cell disease clinical trials: patient-reported outcomes, pain, and the brain. (Farrell AT, Panepinto J, Carroll CP, Darbari DS, Desai AA, King AA, Adams RJ, Barber TD, Brandow AM, DeBaun MR, Donahue MJ, Gupta K, Hankins JS, Kameka M, Kirkham FJ, Luksenburg H, Miller S, Oneal PA, Rees DC, Setse R, Sheehan VA, Strouse J, Stucky CL, Werner EM, Wood JC, Zempsky WT) Blood Adv 2019 Dec 10;3(23):3982-4001 PMID: 31809538 PMCID: PMC6963237 SCOPUS ID: 2-s2.0-85076356716 12/07/2019 46 Citations2019 sickle cell disease guidelines by the American Society of Hematology: methodology, challenges, and innovations. (Murad MH, Liem RI, Lang ES, Akl EA, Meerpohl JJ, DeBaun MR, Tisdale JF, Brandow AM, Lanzkron SM, Chou ST, Webb S, Mustafa RA) Blood Adv 2019 Dec 10;3(23):3945-3950 PMID: 31794603 PMCID: PMC6963245 SCOPUS ID: 2-s2.0-85076339236 12/04/2019 15 CitationsNeuropathic pain in individuals with sickle cell disease. (Sharma D, Brandow AM) Neurosci Lett 2020 Jan 01;714:134445 PMID: 31454562 SCOPUS ID: 2-s2.0-85073505390 08/28/2019 15 CitationsInterventions for treating neuropathic pain in people with sickle cell disease. (Asnani MR, Francis DK, Brandow AM, Hammond Gabbadon CE, Ali A) Cochrane Database Syst Rev 2019 Jul 05;7(7):CD012943 PMID: 31273755 PMCID: PMC6609827 SCOPUS ID: 2-s2.0-85068594834 07/06/2019 2 CitationsGabapentin alleviates chronic spontaneous pain and acute hypoxia-related pain in a mouse model of sickle cell disease. (Sadler KE, Langer SN, Menzel AD, Moehring F, Erb AN, Brandow AM, Stucky CL) Br J Haematol 2019 Oct;187(2):246-260 PMID: 31247672 PMCID: PMC6786911 SCOPUS ID: 2-s2.0-85068153982 06/28/2019 11 CitationsLongitudinal Trend in Emergency Department Reliance for Pain Among Sickle Cell Disease Patients in Wisconsin. (Singh A, Yan K, Brandow AM, Panepinto JA) J Pediatr Hematol Oncol 2019 Oct;41(7):e438-e442 PMID: 31219908 SCOPUS ID: 2-s2.0-85072747381 06/21/2019 6 CitationsChronic pain in adults with sickle cell disease is associated with alterations in functional connectivity of the brain. (Karafin MS, Chen G, Wandersee NJ, Brandow AM, Hurley RW, Simpson P, Ward D, Li SJ, Field JJ) PLoS One 2019;14(5):e0216994 PMID: 31107926 PMCID: PMC6527293 SCOPUS ID: 2-s2.0-85066063764 05/21/2019 18 CitationsChildren and adolescents with sickle cell disease have worse cold and mechanical hypersensitivity during acute painful events. (Brandow AM, Hansen K, Nugent M, Pan A, Panepinto JA, Stucky CL) Pain 2019 Feb;160(2):407-416 PMID: 30247266 PMCID: PMC6768435 SCOPUS ID: 2-s2.0-85060395341 09/25/2018 20 CitationsSickle Cell Clinical Research and Intervention Program (SCCRIP): A lifespan cohort study for sickle cell disease progression from the pediatric stage into adulthood. (Hankins JS, Estepp JH, Hodges JR, Villavicencio MA, Robison LL, Weiss MJ, Kang G, Schreiber JE, Porter JS, Kaste SC, Saving KL, Bryant PC, Deyo JE, Nottage KA, King AA, Brandow AM, Lebensburger JD, Adesina O, Chou ST, Zemel BS, Smeltzer MP, Wang WC, Gurney JG) Pediatr Blood Cancer 2018 Sep;65(9):e27228 PMID: 29797644 SCOPUS ID: 2-s2.0-85050383963 05/26/2018 51 CitationsKey Components of Pain Management for Children and Adults with Sickle Cell Disease. (Brandow AM, DeBaun MR) Hematol Oncol Clin North Am 2018 Jun;32(3):535-550 PMID: 29729787 PMCID: PMC6800257 SCOPUS ID: 2-s2.0-85046430141 05/08/2018 31 CitationsResponsiveness of Patient-Reported Outcome Measurement Information System (PROMIS) pain domains and disease-specific patient-reported outcome measures in children and adults with sickle cell disease. (Curtis S, Brandow AM) Hematology Am Soc Hematol Educ Program 2017 Dec 08;2017(1):542-545 PMID: 29222303 PMCID: PMC6142574 SCOPUS ID: 2-s2.0-85038431497 12/10/2017 8 CitationsPain-measurement tools in sickle cell disease: where are we now? (Darbari DS, Brandow AM) Hematology Am Soc Hematol Educ Program 2017 Dec 08;2017(1):534-541 PMID: 29222302 PMCID: PMC6142608 SCOPUS ID: 2-s2.0-85038415798 12/10/2017 20 CitationsSickle cell disease: a natural model of acute and chronic pain. (Brandow AM, Zappia KJ, Stucky CL) Pain 2017 Apr;158 Suppl 1(Suppl 1):S79-S84 PMID: 28221286 PMCID: PMC5350013 SCOPUS ID: 2-s2.0-85028915679 02/22/2017 38 CitationsPatient-reported neuropathic pain in adolescent and young adult cancer patients. (Acquazzino MA, Igler EC, Dasgupta M, Simpson P, Browning MB, Brandow AM) Pediatr Blood Cancer 2017 Mar;64(3) PMID: 27896941 SCOPUS ID: 2-s2.0-85006275580 11/30/2016 5 CitationsSubstance P is increased in patients with sickle cell disease and associated with haemolysis and hydroxycarbamide use. (Brandow AM, Wandersee NJ, Dasgupta M, Hoffmann RG, Hillery CA, Stucky CL, Panepinto JA) Br J Haematol 2016 Oct;175(2):237-245 PMID: 27539682 PMCID: PMC5063705 SCOPUS ID: 2-s2.0-84994551716 08/20/2016 29 CitationsImpact of emergency department care on outcomes of acute pain events in children with sickle cell disease. (Brandow AM, Nimmer M, Simmons T, Charles Casper T, Cook LJ, Chumpitazi CE, Paul Scott J, Panepinto JA, Brousseau DC) Am J Hematol 2016 Dec;91(12):1175-1180 PMID: 27517842 SCOPUS ID: 2-s2.0-84984821843 08/16/2016 22 CitationsClinical Interpretation of Quantitative Sensory Testing as a Measure of Pain Sensitivity in Patients With Sickle Cell Disease. (Brandow AM, Panepinto JA) J Pediatr Hematol Oncol 2016 May;38(4):288-93 PMID: 26907660 PMCID: PMC4856159 SCOPUS ID: 2-s2.0-84959170292 02/26/2016 29 CitationsPharmacokinetics and bioequivalence of a liquid formulation of hydroxyurea in children with sickle cell anemia. (Estepp JH, Melloni C, Thornburg CD, Wiczling P, Rogers Z, Rothman JA, Green NS, Liem R, Brandow AM, Crary SE, Howard TH, Morris MH, Lewandowski A, Garg U, Jusko WJ, Neville KA, Best Pharmaceuticals for Children Act-Pediatric Trials Network Administrative Core Committee) J Clin Pharmacol 2016 Mar;56(3):298-306 PMID: 26201504 PMCID: PMC4892120 SCOPUS ID: 2-s2.0-84958113265 07/24/2015 17 CitationsEarly insights into the neurobiology of pain in sickle cell disease: A systematic review of the literature. (Brandow AM, Farley RA, Panepinto JA) Pediatr Blood Cancer 2015 Sep;62(9):1501-11 PMID: 25976161 PMCID: PMC4515148 SCOPUS ID: 2-s2.0-84938209147 05/16/2015 50 CitationsA Comparison of Pain Assessment Measures in Pediatric Sickle Cell Disease: Visual Analog Scale Versus Numeric Rating Scale. (Myrvik MP, Drendel AL, Brandow AM, Yan K, Hoffmann RG, Panepinto JA) J Pediatr Hematol Oncol 2015 Apr;37(3):190-4 PMID: 25575295 SCOPUS ID: 2-s2.0-84926407202 01/13/2015 22 CitationsUpdate on the use of hydroxyurea therapy in sickle cell disease. (Wong TE, Brandow AM, Lim W, Lottenberg R) Blood 2014 Dec 18;124(26):3850-7; quiz 4004 PMID: 25287707 PMCID: PMC4271176 SCOPUS ID: 2-s2.0-84919464653 10/08/2014 79 CitationsThe use of neuropathic pain drugs in children with sickle cell disease is associated with older age, female sex, and longer length of hospital stay. (Brandow AM, Farley RA, Dasgupta M, Hoffmann RG, Panepinto JA) J Pediatr Hematol Oncol 2015 Jan;37(1):10-5 PMID: 25222053 PMCID: PMC4270887 SCOPUS ID: 2-s2.0-84920604026 09/16/2014 25 CitationsDo difficulties in swallowing medication impede the use of hydroxyurea in children? (Bekele E, Thornburg CD, Brandow AM, Sharma M, Smaldone AM, Jin Z, Green NS) Pediatr Blood Cancer 2014 Sep;61(9):1536-9 PMID: 24753149 PMCID: PMC4184198 SCOPUS ID: 2-s2.0-84904417157 04/23/2014 16 CitationsNeuropathic pain in patients with sickle cell disease. (Brandow AM, Farley RA, Panepinto JA) Pediatr Blood Cancer 2014 Mar;61(3):512-7 PMID: 24167104 PMCID: PMC4357477 SCOPUS ID: 2-s2.0-84892498517 10/30/2013 73 CitationsAcademic attainment findings in children with sickle cell disease. (Epping AS, Myrvik MP, Newby RF, Panepinto JA, Brandow AM, Scott JP) J Sch Health 2013 Aug;83(8):548-53 PMID: 23834606 SCOPUS ID: 2-s2.0-84880118395 07/10/2013 35 CitationsClinically meaningful measurement of pain in children with sickle cell disease. (Myrvik MP, Brandow AM, Drendel AL, Yan K, Hoffmann RG, Panepinto JA) Pediatr Blood Cancer 2013 Oct;60(10):1689-95 PMID: 23776145 PMCID: PMC3993972 SCOPUS ID: 2-s2.0-84881538085 06/19/2013 31 CitationsAssessment of communication modes in patients and families with sickle cell disease. (Anderson C, Torres S, Gokuli S, Brandow AM, Panepinto JA) Pediatr Blood Cancer 2013 May;60(5):887 PMID: 23450782 SCOPUS ID: 2-s2.0-84874953454 03/02/2013 2 CitationsPatients with sickle cell disease have increased sensitivity to cold and heat. (Brandow AM, Stucky CL, Hillery CA, Hoffmann RG, Panepinto JA) Am J Hematol 2013 Jan;88(1):37-43 PMID: 23115062 PMCID: PMC3552380 SCOPUS ID: 2-s2.0-84871433814 11/02/2012 118 Citations"Sickle Cell Disease in the Emergency Department: Atypical Complications and Management". (Brandow AM, Liem R) Clin Pediatr Emerg Med 2011 Sep 01;12(3):202-212 PMID: 21927581 PMCID: PMC3172721 SCOPUS ID: 2-s2.0-80051764376 09/20/2011 7 CitationsMonitoring toxicity, impact, and adherence of hydroxyurea in children with sickle cell disease. (Brandow AM, Panepinto JA) Am J Hematol 2011 Sep;86(9):804-6 PMID: 21815183 PMCID: PMC3804029 SCOPUS ID: 2-s2.0-80051815757 08/05/2011 27 CitationsTransient receptor potential vanilloid 1 mediates pain in mice with severe sickle cell disease. (Hillery CA, Kerstein PC, Vilceanu D, Barabas ME, Retherford D, Brandow AM, Wandersee NJ, Stucky CL) Blood 2011 Sep 22;118(12):3376-83 PMID: 21708890 PMCID: PMC3179403 SCOPUS ID: 2-s2.0-80053217106 06/29/2011 118 CitationsThe impact of a multidisciplinary pain management model on sickle cell disease pain hospitalizations. (Brandow AM, Weisman SJ, Panepinto JA) Pediatr Blood Cancer 2011 May;56(5):789-93 PMID: 21370412 PMCID: PMC3069506 SCOPUS ID: 2-s2.0-79952147106 03/04/2011 26 CitationsThe impact of a multidisciplinary pain management model on sickle cell disease pain hospitalizations. (Brandow AM et al.) Pediatr Blood Cancer 2010 Dec 15: PMID: 21162071 12/17/2010 Hydroxyurea use in sickle cell disease: the battle with low prescription rates, poor patient compliance and fears of toxicities. (Brandow AM, Panepinto JA) Expert Rev Hematol 2010 Jun;3(3):255-60 PMID: 21082977 PMCID: PMC3793890 SCOPUS ID: 2-s2.0-77953494025 11/19/2010 82 CitationsHydroxyurea in children with sickle cell disease: practice patterns and barriers to utilization. (Brandow AM, Jirovec DL, Panepinto JA) Am J Hematol 2010 Aug;85(8):611-3 PMID: 20658592 PMCID: PMC2911651 SCOPUS ID: 2-s2.0-77955490414 07/27/2010 76 CitationsVaso-occlusive painful events in sickle cell disease: impact on child well-being. (Brandow AM, Brousseau DC, Pajewski NM, Panepinto JA) Pediatr Blood Cancer 2010 Jan;54(1):92-7 PMID: 19653296 PMCID: PMC3114448 SCOPUS ID: 2-s2.0-73349130023 08/05/2009 79 CitationsDissatisfaction with hospital care for children with sickle cell disease not due only to race and chronic disease. (Brousseau DC, Mukonje T, Brandow AM, Nimmer M, Panepinto JA) Pediatr Blood Cancer 2009 Aug;53(2):174-8 PMID: 19350642 SCOPUS ID: 2-s2.0-67649983606 04/08/2009 28 CitationsPostdischarge pain, functional limitations and impact on caregivers of children with sickle cell disease treated for painful events. (Brandow AM, Brousseau DC, Panepinto JA) Br J Haematol 2009 Mar;144(5):782-8 PMID: 19055663 PMCID: PMC3118502 SCOPUS ID: 2-s2.0-58849088040 12/06/2008 38 CitationsParental perception of quality of hospital care for children with sickle cell disease. (Kam J, Panepinto JA, Brandow AM, Brousseau DC) WMJ 2008 May;107(3):131-5 PMID: 18575097 SCOPUS ID: 2-s2.0-44849108027 06/26/2008 4 Citations
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