Changes in description naming for common and proper nouns after left anterior temporal lobectomy. Epilepsy Behav 2020 May;106:106912
Date
03/18/2020Pubmed ID
32179500Pubmed Central ID
PMC7195239DOI
10.1016/j.yebeh.2020.106912Scopus ID
2-s2.0-85081244333 (requires institutional sign-in at Scopus site) 9 CitationsAbstract
Numerous studies have shown that surgical resection of the left anterior temporal lobe (ATL) is associated with a decline in object naming ability (Hermann et al., 1999). In contrast, few studies have examined the effects of left ATL surgery on auditory description naming (ADN) or category-specific naming. Compared with object naming, which loads heavily on visual recognition processes, ADN provides a more specific measure of concept retrieval. The present study examined ADN declines in a large group of patients who were tested before and after left ATL surgery, using a 2 × 2 × 2 factorial manipulation of uniqueness (common vs. proper nouns), taxonomic category (living vs. nonliving things), and time (pre- vs. postsurgery). Significant declines occurred across all categories but were substantially larger for proper living (PL) concepts, i.e., famous individuals. The disproportionate decline in PL noun naming relative to other conditions is consistent with the notion that the left ATL is specialized not only for retrieval of unique entity concepts, but also plays a role in processing social concepts and person-specific features.
Author List
Swanson SJ, Conant LL, Humphries CJ, LeDoux M, Raghavan M, Mueller WM, Allen L, Gross WL, Anderson CT, Carlson CE, Busch RM, Lowe M, Tivarus ME, Drane DL, Loring DW, Jacobs M, Morgan VL, Szaflarski J, Bonilha L, Bookheimer S, Grabowski T, Phatak V, Vannest J, Binder JR, FMRI in Anterior Temporal Epilepsy Surgery (FATES) studyAuthors
Jeffrey R. Binder MD Professor in the Neurology department at Medical College of WisconsinChad Carlson MD Professor in the Neurology department at Medical College of Wisconsin
William Gross MD, PhD Assistant Professor in the Anesthesiology department at Medical College of Wisconsin
Wade M. Mueller MD Professor in the Neurosurgery department at Medical College of Wisconsin
Manoj Raghavan MD, PhD Professor in the Neurology department at Medical College of Wisconsin
Sara J. Swanson PhD Chief, Professor in the Neurology department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
AdultAnterior Temporal Lobectomy
Drug Resistant Epilepsy
Female
Humans
Language
Male
Middle Aged
Neuropsychological Tests
Prospective Studies
Temporal Lobe
Vocabulary
