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Manoj Raghavan MD, PhD

Manoj Raghavan MD, PhD profile photo picture

Professor

Institution: Medical College of Wisconsin
Department: Neurology
Division: General
Program: Epilepsy

Member of the Neuroscience Research Center
Member of the Wisconsin Institute of NeuroScience (WINS)

Research Areas of Interest

  • Anterior Temporal Lobectomy
  • Biomarkers
  • Brain Mapping
  • Cortical Excitability
  • Cortical Synchronization
  • Drug Resistant Epilepsy
  • Electrocorticography
  • Electroencephalography
  • Epilepsy
  • Epilepsy, Temporal Lobe
  • Functional Laterality
  • Language
  • Magnetoencephalography
  • Seizures
  • Support Vector Machine

    • Research Experience

  • Anterior Temporal Lobectomy
  • Brain Mapping
  • Connectome
  • Electrodes, Implanted
  • Electroencephalography
  • Epilepsies, Partial
  • Epilepsy
  • Epilepsy, Temporal Lobe
  • Functional Laterality
  • Humans
  • Image Processing, Computer-Assisted
  • Imaging, Three-Dimensional
  • Language
  • Language Tests
  • Magnetoencephalography
  • Neural Pathways
  • Support Vector Machine
  • Temporal Lobe

    • Clinical Expertise

  • Adult
  • Anterior Temporal Lobectomy
  • Brain Mapping
  • Connectome
  • Electrodes, Implanted
  • Electroencephalography
  • Epilepsies, Partial
  • Epilepsy
  • Epilepsy, Temporal Lobe
  • Functional Laterality
  • Humans
  • Image Processing, Computer-Assisted
  • Language
  • Language Tests
  • Magnetoencephalography
  • Neural Pathways
  • Temporal Lobe

    • Methodologies and Techniques

  • Anterior Temporal Lobectomy
  • Brain Mapping
  • Contrast Sensitivity
  • Electrocorticography
  • Electroencephalography
  • Image Processing, Computer-Assisted
  • Imaging, Three-Dimensional
  • Language Tests
  • Magnetoencephalography
  • Psychophysics
  • Signal Processing, Computer-Assisted

    • Leadership Positions

  • Medical Director, MEG Program
  • Director, Adult Comprehensive Epilepsy Program

    • Publications (37)

  • Gamma amplitude-envelope correlations are strongly elevated within hyperexcitable networks in focal epilepsy. (Raghavan M, Pilet J, Carlson C, Anderson CT, Mueller W, Lew S, Ustine C, Shah-Basak P, Youssofzadeh V, Beardsley SA) Sci Rep 2024 Jul 31;14(1):17736 PMID: 39085280 PMCID: PMC11291981 SCOPUS ID: 2-s2.0-85200293097 08/01/2024    
  • T1-/T2-weighted ratio reveals no alterations to gray matter myelination in temporal lobe epilepsy. (Denis C, Dabbs K, Nair VA, Mathis J, Almane DN, Lakshmanan A, Nencka A, Birn RM, Conant L, Humphries C, Felton E, Raghavan M, DeYoe EA, Binder JR, Hermann B, Prabhakaran V, Bendlin BB, Meyerand ME, Boly M, Struck AF) Ann Clin Transl Neurol 2023 Nov;10(11):2149-2154 PMID: 37872734 PMCID: PMC10647008 SCOPUS ID: 2-s2.0-85174616650 10/24/2023    
  • Large-scale brain networks and intra-axial tumor surgery: a narrative review of functional mapping techniques, critical needs, and scientific opportunities. (Boerger TF, Pahapill P, Butts AM, Arocho-Quinones E, Raghavan M, Krucoff MO) Front Hum Neurosci 2023;17:1170419 PMID: 37520929 PMCID: PMC10372448 SCOPUS ID: 2-s2.0-85165910739 07/31/2023       2 Citations
  • Mapping and decoding cortical engagement during motor imagery, mental arithmetic, and silent word generation using MEG. (Youssofzadeh V, Roy S, Chowdhury A, Izadysadr A, Parkkonen L, Raghavan M, Prasad G) Hum Brain Mapp 2023 Jun 01;44(8):3324-3342 PMID: 36987698 PMCID: PMC10171552 SCOPUS ID: 2-s2.0-85151932139 03/30/2023       6 Citations
  • Responsive Neurostimulation of the Anterior Thalamic Nuclei in Refractory Genetic Generalized Epilepsy: A Case Series. (O'Donnell CM, Swanson SJ, Carlson CE, Raghavan M, Pahapill PA, Anderson CT) Brain Sci 2023 Feb 14;13(2) PMID: 36831867 PMCID: PMC9954640 SCOPUS ID: 2-s2.0-85148880498 02/26/2023       3 Citations
  • Late dominance of the right hemisphere during narrative comprehension. (Youssofzadeh V, Conant L, Stout J, Ustine C, Humphries C, Gross WL, Shah-Basak P, Mathis J, Awe E, Allen L, DeYoe EA, Carlson C, Anderson CT, Maganti R, Hermann B, Nair VA, Prabhakaran V, Meyerand B, Binder JR, Raghavan M) Neuroimage 2022 Dec 01;264:119749 PMID: 36379420 PMCID: PMC9772156 SCOPUS ID: 2-s2.0-85141915479 11/16/2022       3 Citations
  • Anti-seizure medication treatment trials prior to pre-surgical evaluation. (Pandya V, Bauer P, Thompson S, Anderson CT, Raghavan M, Carlson C) Epilepsy Behav Rep 2022;20:100565 PMID: 36119947 PMCID: PMC9474306 SCOPUS ID: 2-s2.0-85137614020 09/20/2022       1 Citation
  • Prediction of Naming Outcome With fMRI Language Lateralization in Left Temporal Epilepsy Surgery. (Gross WL, Helfand AI, Swanson SJ, Conant LL, Humphries CJ, Raghavan M, Mueller WM, Busch RM, Allen L, Anderson CT, Carlson CE, Lowe MJ, Langfitt JT, Tivarus ME, Drane DL, Loring DW, Jacobs M, Morgan VL, Allendorfer JB, Szaflarski JP, Bonilha L, Bookheimer S, Grabowski T, Vannest J, Binder JR, FMRI in Anterior Temporal Epilepsy Surgery (FATES) Study) Neurology 2022 Jun 07;98(23):e2337-e2346 PMID: 35410903 PMCID: PMC9202528 SCOPUS ID: 2-s2.0-85131545635 04/13/2022       14 Citations
  • Regional and global resting-state functional MR connectivity in temporal lobe epilepsy: Results from the Epilepsy Connectome Project. (Struck AF, Boly M, Hwang G, Nair V, Mathis J, Nencka A, Conant LL, DeYoe EA, Raghavan M, Prabhakaran V, Binder JR, Meyerand ME, Hermann BP) Epilepsy Behav 2021 Apr;117:107841 PMID: 33611101 PMCID: PMC8035304 SCOPUS ID: 2-s2.0-85100881402 02/22/2021       21 Citations
  • Temporal lobe regions essential for preserved picture naming after left temporal epilepsy surgery. (Binder JR, Tong JQ, Pillay SB, Conant LL, Humphries CJ, Raghavan M, Mueller WM, Busch RM, Allen L, Gross WL, Anderson CT, Carlson CE, Lowe MJ, Langfitt JT, Tivarus ME, Drane DL, Loring DW, Jacobs M, Morgan VL, Allendorfer JB, Szaflarski JP, Bonilha L, Bookheimer S, Grabowski T, Vannest J, Swanson SJ, fMRI in Anterior Temporal Epilepsy Surgery (FATES) study) Epilepsia 2020 Sep;61(9):1939-1948 PMID: 32780878 PMCID: PMC7722029 SCOPUS ID: 2-s2.0-85089258019 08/12/2020       37 Citations
  • Network, clinical and sociodemographic features of cognitive phenotypes in temporal lobe epilepsy. (Hermann B, Conant LL, Cook CJ, Hwang G, Garcia-Ramos C, Dabbs K, Nair VA, Mathis J, Bonet CNR, Allen L, Almane DN, Arkush K, Birn R, DeYoe EA, Felton E, Maganti R, Nencka A, Raghavan M, Shah U, Sosa VN, Struck AF, Ustine C, Reyes A, Kaestner E, McDonald C, Prabhakaran V, Binder JR, Meyerand ME) Neuroimage Clin 2020;27:102341 PMID: 32707534 PMCID: PMC7381697 SCOPUS ID: 2-s2.0-85088252788 07/25/2020       52 Citations
  • Mapping language from MEG beta power modulations during auditory and visual naming. (Youssofzadeh V, Stout J, Ustine C, Gross WL, Conant LL, Humphries CJ, Binder JR, Raghavan M) Neuroimage 2020 Oct 15;220:117090 PMID: 32593799 SCOPUS ID: 2-s2.0-85086940876 07/01/2020       15 Citations
  • Neuroticism in temporal lobe epilepsy is associated with altered limbic-frontal lobe resting-state functional connectivity. (Rivera Bonet CN, Hwang G, Hermann B, Struck AF, J Cook C, A Nair V, Mathis J, Allen L, Almane DN, Arkush K, Birn R, Conant LL, DeYoe EA, Felton E, Maganti R, Nencka A, Raghavan M, Shah U, Sosa VN, Ustine C, Prabhakaran V, Binder JR, Meyerand ME) Epilepsy Behav 2020 Sep;110:107172 PMID: 32554180 PMCID: PMC7483612 SCOPUS ID: 2-s2.0-85086476142 06/20/2020       9 Citations
  • Changes in description naming for common and proper nouns after left anterior temporal lobectomy. (Swanson SJ, Conant LL, Humphries CJ, LeDoux M, Raghavan M, Mueller WM, Allen L, Gross WL, Anderson CT, Carlson CE, Busch RM, Lowe M, Tivarus ME, Drane DL, Loring DW, Jacobs M, Morgan VL, Szaflarski J, Bonilha L, Bookheimer S, Grabowski T, Phatak V, Vannest J, Binder JR, FMRI in Anterior Temporal Epilepsy Surgery (FATES) study) Epilepsy Behav 2020 May;106:106912 PMID: 32179500 PMCID: PMC7195239 SCOPUS ID: 2-s2.0-85081244333 03/18/2020       9 Citations
  • Clinical Reasoning: Ketogenic diet in adult super-refractory status epilepticus. (Noviawaty I, Olaru E, Rondello C, Fitzsimmons B, Raghavan M) Neurology 2020 Mar 24;94(12):541-546 PMID: 32107326 SCOPUS ID: 2-s2.0-85082342142 02/29/2020       4 Citations
  • Brain aging in temporal lobe epilepsy: Chronological, structural, and functional. (Hwang G, Hermann B, Nair VA, Conant LL, Dabbs K, Mathis J, Cook CJ, Rivera-Bonet CN, Mohanty R, Zhao G, Almane DN, Nencka A, Felton E, Struck AF, Birn R, Maganti R, Humphries CJ, Raghavan M, DeYoe EA, Bendlin BB, Prabhakaran V, Binder JR, Meyerand ME) Neuroimage Clin 2020;25:102183 PMID: 32058319 PMCID: PMC7016276 SCOPUS ID: 2-s2.0-85079141146 02/15/2020       30 Citations
  • Neuroanatomical correlates of personality traits in temporal lobe epilepsy: Findings from the Epilepsy Connectome Project. (Rivera Bonet CN, Hermann B, Cook CJ, Hwang G, Dabbs K, Nair V, Forseth C, Mathis J, Allen L, Almane DN, Arkush K, Birn R, Conant LL, DeYoe EA, Felton E, Humphries CJ, Kraegel P, Maganti R, Nencka A, Nwoke O, Raghavan M, Rozman M, Shah U, Sosa VN, Struck AF, Tellapragada N, Ustine C, Ward BD, Prabhakaran V, Binder JR, Meyerand ME) Epilepsy Behav 2019 Sep;98(Pt A):220-227 PMID: 31387000 PMCID: PMC6732015 SCOPUS ID: 2-s2.0-85071832268 08/07/2019       16 Citations
  • Generation and propagation of the action potential. (Raghavan M, Fee D, Barkhaus PE) Handb Clin Neurol 2019;160:3-22 PMID: 31277855 SCOPUS ID: 2-s2.0-85068161532 07/07/2019       32 Citations
  • Cognitive slowing and its underlying neurobiology in temporal lobe epilepsy. (Hwang G, Dabbs K, Conant L, Nair VA, Mathis J, Almane DN, Nencka A, Birn R, Humphries C, Raghavan M, DeYoe EA, Struck AF, Maganti R, Binder JR, Meyerand E, Prabhakaran V, Hermann B) Cortex 2019 Aug;117:41-52 PMID: 30927560 PMCID: PMC6650302 SCOPUS ID: 2-s2.0-85063324806 03/31/2019       41 Citations
  • Using Low-Frequency Oscillations to Detect Temporal Lobe Epilepsy with Machine Learning. (Hwang G, Nair VA, Mathis J, Cook CJ, Mohanty R, Zhao G, Tellapragada N, Ustine C, Nwoke OO, Rivera-Bonet C, Rozman M, Allen L, Forseth C, Almane DN, Kraegel P, Nencka A, Felton E, Struck AF, Birn R, Maganti R, Conant LL, Humphries CJ, Hermann B, Raghavan M, DeYoe EA, Binder JR, Meyerand E, Prabhakaran V) Brain Connect 2019 Mar;9(2):184-193 PMID: 30803273 PMCID: PMC6484357 SCOPUS ID: 2-s2.0-85063084464 02/26/2019       17 Citations
  • Effective Connectivity Within the Default Mode Network in Left Temporal Lobe Epilepsy: Findings from the Epilepsy Connectome Project. (Cook CJ, Hwang G, Mathis J, Nair VA, Conant LL, Allen L, Almane DN, Birn R, DeYoe EA, Felton E, Forseth C, Humphries CJ, Kraegel P, Nencka A, Nwoke O, Raghavan M, Rivera-Bonet C, Rozman M, Tellapragada N, Ustine C, Ward BD, Struck A, Maganti R, Hermann B, Prabhakaran V, Binder JR, Meyerand ME) Brain Connect 2019 Mar;9(2):174-183 PMID: 30398367 PMCID: PMC6444922 SCOPUS ID: 2-s2.0-85063100708 11/07/2018       30 Citations
  • MEG language lateralization in partial epilepsy using dSPM of auditory event-related fields. (Raghavan M, Li Z, Carlson C, Anderson CT, Stout J, Sabsevitz DS, Swanson SJ, Binder JR) Epilepsy Behav 2017 Aug;73:247-255 PMID: 28662463 SCOPUS ID: 2-s2.0-85021207430 07/01/2017       15 Citations
  • Nonseizure SUDEP: Sudden unexpected death in epilepsy without preceding epileptic seizures. (Lhatoo SD, Nei M, Raghavan M, Sperling M, Zonjy B, Lacuey N, Devinsky O) Epilepsia 2016 Jul;57(7):1161-8 PMID: 27221596 PMCID: PMC5541994 SCOPUS ID: 2-s2.0-84977572730 05/26/2016       84 Citations
  • Functional mri in the presurgical epilepsy evaluation (Swanson SJ, Binder JR, Raghavan M, Euler M) Handbook on the Neuropsychology of Epilepsy 1 January 2015:169-194 SCOPUS ID: 2-s2.0-84945138314 01/01/2015       5 Citations
  • Magnetoencephalography in the preoperative evaluation for epilepsy surgery. (Anderson CT, Carlson CE, Li Z, Raghavan M) Curr Neurol Neurosci Rep 2014 May;14(5):446 PMID: 24652454 SCOPUS ID: 2-s2.0-84897467116 03/22/2014       21 Citations
  • Naming outcome after left or right temporal lobectomy in patients with bilateral language representation by Wada testing. (Janecek JK, Winstanley FS, Sabsevitz DS, Raghavan M, Mueller W, Binder JR, Swanson SJ) Epilepsy Behav 2013 Jul;28(1):95-8 PMID: 23688676 PMCID: PMC3673014 SCOPUS ID: 2-s2.0-84878169164 05/22/2013       8 Citations
  • Naming outcome prediction in patients with discordant Wada and fMRI language lateralization. (Janecek JK, Swanson SJ, Sabsevitz DS, Hammeke TA, Raghavan M, Mueller W, Binder JR) Epilepsy Behav 2013 May;27(2):399-403 PMID: 23541860 PMCID: PMC3644871 SCOPUS ID: 2-s2.0-84876127499 04/02/2013       51 Citations
  • Language lateralization by fMRI and Wada testing in 229 patients with epilepsy: rates and predictors of discordance. (Janecek JK, Swanson SJ, Sabsevitz DS, Hammeke TA, Raghavan M, E Rozman M, Binder JR) Epilepsia 2013 Feb;54(2):314-22 PMID: 23294162 PMCID: PMC3649863 SCOPUS ID: 2-s2.0-84873409900 01/09/2013       150 Citations
  • 3D visualization of subdural electrode shift as measured at craniotomy reopening. (LaViolette PS, Rand SD, Ellingson BM, Raghavan M, Lew SM, Schmainda KM, Mueller W) Epilepsy Res 2011 Mar;94(1-2):102-9 PMID: 21334178 PMCID: PMC4329774 SCOPUS ID: 2-s2.0-79952455401 02/22/2011       32 Citations
  • Three-dimensional visualization of subdural electrodes for presurgical planning. (LaViolette PS, Rand SD, Raghavan M, Ellingson BM, Schmainda KM, Mueller W) Neurosurgery 2011 Mar;68(1 Suppl Operative):152-60; discussion 160-1 PMID: 21206319 PMCID: PMC4339031 SCOPUS ID: 2-s2.0-79951772694 01/06/2011       13 Citations
  • A comparison of two fMRI methods for predicting verbal memory decline after left temporal lobectomy: language lateralization versus hippocampal activation asymmetry. (Binder JR, Swanson SJ, Sabsevitz DS, Hammeke TA, Raghavan M, Mueller WM) Epilepsia 2010 Apr;51(4):618-26 PMID: 19817807 PMCID: PMC2945221 SCOPUS ID: 2-s2.0-77951658694 10/13/2009       94 Citations
  • Use of preoperative functional MRI to predict verbal memory decline after temporal lobe epilepsy surgery. (Binder JR, Sabsevitz DS, Swanson SJ, Hammeke TA, Raghavan M, Mueller WM) Epilepsia 2008 Aug;49(8):1377-94 PMID: 18435753 PMCID: PMC2943848 SCOPUS ID: 2-s2.0-48149087450 04/26/2008       192 Citations
  • Localizing epileptogenic regions in partial epilepsy using three-dimensional statistical parametric maps of background EEG source spectra. (Alper K, Raghavan M, Isenhart R, Howard B, Doyle W, John R, Prichep L) Neuroimage 2008 Feb 01;39(3):1257-65 PMID: 18024085 SCOPUS ID: 2-s2.0-37849005346 11/21/2007       14 Citations
  • Prediction of false-positive recognition errors during Wada testing. (Barr WB, Raghavan M, Kim Nelson P, Devinsky O) J Clin Exp Neuropsychol 2006 Oct;28(7):1065-72 PMID: 16840236 SCOPUS ID: 2-s2.0-33746223117 07/15/2006       1 Citation
  • Epilepsy (Binder JR, Raghavan M) Functional MRI: Applications in Clinical Neurology and Psychiatry 1 January 2006:81-113 SCOPUS ID: 2-s2.0-79951670308 01/01/2006       3 Citations
  • Explaining the low spatial frequency cut-off in contrast sensitivity (Majaj N, Raghavan M) Investigative Ophthalmology and Visual Science 15 February 1996;37(3) SCOPUS ID: 2-s2.0-33750184762 02/15/1996    
  • A self-organizing neural network for locus-addressable associative memory (Raghavan M, Dorai C) 1990:899-904 SCOPUS ID: 2-s2.0-0025566219 01/01/1990    
    • Last update: 08/05/2024