Granulomatous and lymphocytic interstitial lung disease diagnosed by transbronchial lung cryobiopsy. Cryobiology 2020 Dec;97:231-234
Date
08/19/2020Pubmed ID
32810518DOI
10.1016/j.cryobiol.2020.08.004Scopus ID
2-s2.0-85089727939 (requires institutional sign-in at Scopus site) 4 CitationsAbstract
Granulomatous and lymphocytic interstitial lung disease is a pulmonary complication of common variable immune deficiency with significant morbidity and increased mortality. Diagnosis has historically been obtained by surgical lung biopsy as transbronchial biopsy typically yields insufficient tissue for definitive diagnosis from a disease process with a patchy distribution. However, the potential for significant morbidity and mortality with surgical lung biopsy exists, necessitating the development of alternative diagnostic approaches. We present a case of granulomatous and lymphocytic interstitial lung disease confirmed through minimally invasive transbronchial lung cryobiopsy and discuss the role of this modality in diagnosing interstitial lung disease.
Author List
Doan J, Rao N, Kurman JS, Routes JM, Benn BSAuthors
Jonathan S. Kurman MD Associate Professor in the Medicine department at Medical College of WisconsinJohn M. Routes MD Chief, Professor in the Pediatrics department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
BiopsyBronchoscopy
Cryopreservation
Humans
Lung
Lung Diseases, Interstitial
