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Granulomatous and lymphocytic interstitial lung disease diagnosed by transbronchial lung cryobiopsy. Cryobiology 2020 12;97:231-234

Date

08/19/2020

Pubmed ID

32810518

DOI

10.1016/j.cryobiol.2020.08.004

Scopus ID

2-s2.0-85089727939

Abstract

Granulomatous and lymphocytic interstitial lung disease is a pulmonary complication of common variable immune deficiency with significant morbidity and increased mortality. Diagnosis has historically been obtained by surgical lung biopsy as transbronchial biopsy typically yields insufficient tissue for definitive diagnosis from a disease process with a patchy distribution. However, the potential for significant morbidity and mortality with surgical lung biopsy exists, necessitating the development of alternative diagnostic approaches. We present a case of granulomatous and lymphocytic interstitial lung disease confirmed through minimally invasive transbronchial lung cryobiopsy and discuss the role of this modality in diagnosing interstitial lung disease.

Author List

Doan J, Rao N, Kurman JS, Routes JM, Benn BS

Authors

Jonathan S. Kurman MD Assistant Professor in the Medicine department at Medical College of Wisconsin
John M. Routes MD Chief, Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Biopsy
Bronchoscopy
Cryopreservation
Humans
Lung
Lung Diseases, Interstitial