Characterization of NADPH diaphorase activity in rat sympathetic autonomic ganglia--effect of diabetes and aging. Brain Res 1993 Jul 23;617(2):343-8
Date
07/23/1993Pubmed ID
8104662DOI
10.1016/0006-8993(93)91103-yScopus ID
2-s2.0-0027183822 (requires institutional sign-in at Scopus site) 20 CitationsAbstract
NADPH-diaphorase histochemistry, which identifies neural sites of nitric oxide production, demonstrated intensely stained nerve terminals surrounding the cell bodies of a subpopulation of neurons in rat prevertebral celiac and superior mesenteric sympathetic ganglia but failed to comparably label terminals in paravertebral superior cervical ganglia or perikarya in any sympathetic ganglion. The superior mesenteric ganglia of aged and diabetic rats, in which synaptic dysplasia (neuroaxonal dystrophy) is prominent, failed to show involvement of diaphorase containing nerve terminals.
Author List
Schmidt RE, Dorsey DA, McDaniel ML, Corbett JAAuthor
John A. Corbett PhD Chair, Professor in the Biochemistry department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AgingAnimals
Diabetes Mellitus, Experimental
Ganglia, Sympathetic
Male
NADPH Dehydrogenase
Nitric Oxide
Rats
Rats, Inbred F344
Rats, Sprague-Dawley
Synapses
Synaptosomes
Tyrosine 3-Monooxygenase
