Surgical restoration of portal flow corrects procoagulant and anticoagulant deficiencies associated with extrahepatic portal vein thrombosis. J Pediatr 2003 Feb;142(2):197-9
Date
02/14/2003Pubmed ID
12584545DOI
10.1067/mpd.2003.93Scopus ID
2-s2.0-0037324149 (requires institutional sign-in at Scopus site) 102 CitationsAbstract
Extrahepatic portal vein thrombosis (EHPVT) is associated with abnormal circulating procoagulants and anticoagulants. Eleven children with EHPVT and abnormal coagulation factors underwent a mesenterico-left portal vein bypass to restore portal flow. Coagulation factors had returned to normal by one year. The data suggest that portal venous flow is essential for maintaining normal coagulation.
Author List
Mack CL, Superina RA, Whitington PFAuthor
Cara Lynn Mack MD Chief, Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Antithrombin IIIBlood Coagulation Disorders
Child
Factor V
Factor VII
Factor VIII
Female
Fibrin Fibrinogen Degradation Products
Humans
Liver Circulation
Male
Partial Thromboplastin Time
Portal System
Portal Vein
Portasystemic Shunt, Surgical
Prospective Studies
Protein C
Protein S
Prothrombin
Prothrombin Time
Treatment Outcome
Venous Thrombosis