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Surgical restoration of portal flow corrects procoagulant and anticoagulant deficiencies associated with extrahepatic portal vein thrombosis. J Pediatr 2003 Feb;142(2):197-9

Date

02/14/2003

Pubmed ID

12584545

DOI

10.1067/mpd.2003.93

Scopus ID

2-s2.0-0037324149 (requires institutional sign-in at Scopus site)   102 Citations

Abstract

Extrahepatic portal vein thrombosis (EHPVT) is associated with abnormal circulating procoagulants and anticoagulants. Eleven children with EHPVT and abnormal coagulation factors underwent a mesenterico-left portal vein bypass to restore portal flow. Coagulation factors had returned to normal by one year. The data suggest that portal venous flow is essential for maintaining normal coagulation.

Author List

Mack CL, Superina RA, Whitington PF

Author

Cara Lynn Mack MD Chief, Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Antithrombin III
Blood Coagulation Disorders
Child
Factor V
Factor VII
Factor VIII
Female
Fibrin Fibrinogen Degradation Products
Humans
Liver Circulation
Male
Partial Thromboplastin Time
Portal System
Portal Vein
Portasystemic Shunt, Surgical
Prospective Studies
Protein C
Protein S
Prothrombin
Prothrombin Time
Treatment Outcome
Venous Thrombosis