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Transcriptomic perspectives of memory-like NK cells and aging. Genome Med 2022 May 25;14(1):57

Date

05/25/2022

Pubmed ID

35610660

Pubmed Central ID

PMC9129893

DOI

10.1186/s13073-022-01059-1

Scopus ID

2-s2.0-85130685503 (requires institutional sign-in at Scopus site)

Abstract

A recent study highlights the presence of a unique memory-like natural killer (NK) cell subset, which accumulates with aging and appears to associate withdisease severity in COVID-19 patients. While the clinical relevance of memory in NK cells is being debated, the molecular identity of this subset in the form of a single-cell transcriptome is essential to define their origin, longevity, functions, and disease relevance.

Author List

Wang D, Malarkannan S

Author

Subramaniam Malarkannan PhD Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Aging
Humans
Killer Cells, Natural
Transcriptome