Transcriptomic perspectives of memory-like NK cells and aging. Genome Med 2022 May 25;14(1):57
Date
05/25/2022Pubmed ID
35610660Pubmed Central ID
PMC9129893DOI
10.1186/s13073-022-01059-1Scopus ID
2-s2.0-85130685503 (requires institutional sign-in at Scopus site)Abstract
A recent study highlights the presence of a unique memory-like natural killer (NK) cell subset, which accumulates with aging and appears to associate withdisease severity in COVID-19 patients. While the clinical relevance of memory in NK cells is being debated, the molecular identity of this subset in the form of a single-cell transcriptome is essential to define their origin, longevity, functions, and disease relevance.
Author List
Wang D, Malarkannan SAuthor
Subramaniam Malarkannan PhD Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AgingHumans
Killer Cells, Natural
Transcriptome