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Somatosensory deafferentation reveals lateralized roles of proprioception in feedback and adaptive feedforward control of movement and posture. Curr Opin Physiol 2021 Feb;19:141-147

Date

02/01/2021

Pubmed ID

36569335

Pubmed Central ID

PMC9788652

DOI

10.1016/j.cophys.2020.10.005

Scopus ID

2-s2.0-85096562432 (requires institutional sign-in at Scopus site)   19 Citations

Abstract

Proprioception provides crucial information necessary for determining limb position and movement, and plausibly also for updating internal models that might underlie the control of movement and posture. Seminal studies of upper-limb movements in individuals living with chronic, large fiber deafferentation have provided evidence for the role of proprioceptive information in the hypothetical formation and maintenance of internal models to produce accurate motor commands. Vision also contributes to sensorimotor functions but cannot fully compensate for proprioceptive deficits. More recent work has shown that posture and movement control processes are lateralized in the brain, and that proprioception plays a fundamental role in coordinating the contributions of these processes to the control of goal-directed actions. In fact, the behavior of each limb in a deafferented individual resembles the action of a controller in isolation. Proprioception, thus, provides state estimates necessary for the nervous system to efficiently coordinate multiple motor control processes.

Author List

Jayasinghe SAL, Sarlegna FR, Scheidt RA, Sainburg RL

Author

Robert Scheidt BS,MS,PhD Associate Professor in the Biomedical Engineering department at Marquette University