Biliary papillomatosis in three Caucasian patients in a Western centre. Eur J Surg Oncol 2012 Feb;38(2):181-4
Date
12/14/2011Pubmed ID
22154963DOI
10.1016/j.ejso.2011.11.007Scopus ID
2-s2.0-84855843120 (requires institutional sign-in at Scopus site) 10 CitationsAbstract
INTRODUCTION: Biliary papillomatosis (BP) is a rare condition with a strong potential for malignant transformation and cases from Western centres are sparse.(1) We discuss the presentation, investigation and management of this condition in three Caucasian patients and present a review of the existing literature on BP.
PATIENTS AND METHODS: The case notes of three Caucasian patients with BP who presented to our tertiary referral centre were reviewed. Their case histories, investigations and managements are presented. A search of MEDLINE, PubMed and Cochrane databases was performed to review relevant literature around BP.
DISCUSSION: BP is a rare condition characterised by multiple papillary adenomas involving the biliary tree which lead to recurrent attacks of cholangitis. It is a low-grade neoplasm with high malignant potential and should be regarded as a pre-malignant lesion.
Author List
White AD, Young AL, Verbeke C, Brannan R, Smith A, Prasad KRAuthor
Kondragunta Rajendra Prasad MBBS Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Biliary Tract NeoplasmsBiopsy, Needle
Cell Transformation, Neoplastic
Cholangiopancreatography, Endoscopic Retrograde
Cholangitis
Female
Follow-Up Studies
Hepatectomy
Humans
Immunohistochemistry
Liver Transplantation
Magnetic Resonance Imaging
Male
Middle Aged
Papilloma
Rare Diseases
Risk Assessment
Sampling Studies
Survival Rate
Treatment Outcome
United Kingdom