How I diagnose and treat thrombocytopenia in geriatric patients. Blood 2024 Jan 18;143(3):214-223
Date
11/13/2023Pubmed ID
37956435DOI
10.1182/blood.2022017634Scopus ID
2-s2.0-85180443922 (requires institutional sign-in at Scopus site)Abstract
Thrombocytopenia in older individuals is a common but diagnostically challenging condition that has variable clinical impact to those who are affected. Diagnostic approach requires evaluation of the preexisting clinical conditions, detailed review of medications, and assessment for disorders that warrant urgent treatment. In this article, we describe a systematic approach to diagnosis of thrombocytopenia and present a schematic review for management strategies. Three clinical scenarios are presented that are relevant for their prevalence and management challenges in an older adult population. The first scenario addresses primary immune thrombocytopenia (ITP) and reviews different treatment options. The second one addresses complications of thrombocytopenia in management of the myelodysplastic syndrome. The last one reviews diagnostic challenges of drug-induced ITP.
Author List
Foy P, Friedman KD, Michaelis LCAuthors
Kenneth D. Friedman MD Professor in the Medicine department at Medical College of WisconsinLaura Michaelis MD Chief, Professor in the Medicine department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
AgedHumans
Myelodysplastic Syndromes
Purpura, Thrombocytopenic, Idiopathic
Thrombocytopenia
