Medical College of Wisconsin
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Kenneth D. Friedman MD

Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Hematology and Oncology - Medicine
Program: Hematology


Leadership Positions

  • Medical Director
    Hemostasis Reference Laboratory
    BloodCenter of Wisconsin

    Associate Medical Director
    Comprehensive Center for Bleeding Disorders
    BloodCenter of Wisconsin
  • Publications (75)

  • Successful treatment of thrombotic thrombocytopenia with cerebral sinus venous thrombosis following Ad26.COV2.S vaccination. (George G, Friedman KD, Curtis BR, Lind SE) Am J Hematol 2021 08 01;96(8):E301-E303 PMID: 33989437 SCOPUS ID: 2-s2.0-85107284628 05/15/2021       3 Citations
  • Annual incidence and severity of acute episodes in hereditary thrombotic thrombocytopenic purpura. (Tarasco E, Bütikofer L, Friedman KD, George JN, Hrachovinova I, Knöbl PN, Matsumoto M, von Krogh AS, Aebi-Huber I, Cermakova Z, Górska-Kosicka M, Jalowiec KA, Largiadèr CR, Prohászka Z, Sinkovits G, Windyga J, Lämmle B, Kremer Hovinga JA) Blood 2021 06 24;137(25):3563-3575 PMID: 33649760 SCOPUS ID: 2-s2.0-85106725094 03/03/2021       4 Citations
  • Redefining outcomes in immune TTP: an international working group consensus report. (Cuker A, Cataland SR, Coppo P, de la Rubia J, Friedman KD, George JN, Knoebl PN, Kremer Hovinga JA, Lämmle B, Matsumoto M, Pavenski K, Peyvandi F, Sakai K, Sarode R, Thomas MR, Tomiyama Y, Veyradier A, Westwood JP, Scully M) Blood 2021 04 08;137(14):1855-1861 PMID: 33529333 SCOPUS ID: 2-s2.0-85103778501 02/03/2021       13 Citations
  • A microfluidic analysis of thrombus formation in reconstituted whole blood samples comparing spray-dried plasma versus fresh frozen plasma. (Bercovitz RS, Drew CS, Bushee CL, Popovsky MA, Friedman KD, Anani WQ) Vox Sang 2021 May;116(5):540-546 PMID: 33277925 SCOPUS ID: 2-s2.0-85097104531 12/06/2020       1 Citation
  • Compound heterozygous protein C variants undetectable by common laboratory testing causing purpura fulminans after the neonatal period. (MacQuarrie KL, Williams O, Friedman KD, Bercovitz RS) Am J Hematol 2020 12;95(12):1616-1621 PMID: 32833261 SCOPUS ID: 2-s2.0-85091365009 08/25/2020    
  • In Vitro Assessment of von Willebrand Factor in Cryoprecipitate, Antihemophilic Factor/VWF Complex (Human), and Recombinant von Willebrand Factor. (Colling ME, Friedman KD, Dzik WH) Clin Appl Thromb Hemost 2019 Jan-Dec;25:1076029619873976 PMID: 31496264 PMCID: PMC6829641 SCOPUS ID: 2-s2.0-85071967899 09/10/2019    
  • The International Hereditary Thrombotic Thrombocytopenic Purpura Registry: key findings at enrollment until 2017. (van Dorland HA, Taleghani MM, Sakai K, Friedman KD, George JN, Hrachovinova I, Knöbl PN, von Krogh AS, Schneppenheim R, Aebi-Huber I, Bütikofer L, Largiadèr CR, Cermakova Z, Kokame K, Miyata T, Yagi H, Terrell DR, Vesely SK, Matsumoto M, Lämmle B, Fujimura Y, Kremer Hovinga JA, Hereditary TTP Registry) Haematologica 2019 10;104(10):2107-2115 PMID: 30792199 PMCID: PMC6886414 SCOPUS ID: 2-s2.0-85065445111 02/23/2019       41 Citations
  • Performance of a recombinant fusion protein linking coagulation factor IX with recombinant albumin in one-stage clotting assays. (Horn C, Négrier C, Kalina U, Seifert W, Friedman KD) J Thromb Haemost 2019 01;17(1):138-148 PMID: 30418692 PMCID: PMC7379984 SCOPUS ID: 2-s2.0-85058628400 11/13/2018       9 Citations
  • Von Willebrand disease in the United States: perspective from the Zimmerman program. (Flood VH, Abshire TC, Christopherson PA, Friedman KD, Cox Gill J, Montgomery RR, Haberichter SL, Zimmerman Program Investigators) Ann Blood 2018 Jan;3 PMID: 30135959 PMCID: PMC6100783 08/24/2018    
  • Common VWF sequence variants associated with higher VWF and FVIII are less frequent in subjects diagnosed with type 1 VWD. (Flood VH, Johnsen JM, Kochelek C, Slobodianuk TL, Christopherson PA, Haberichter SL, Udani R, Bellissimo DB, Friedman KD, Montgomery RR) Res Pract Thromb Haemost 2018 Apr;2(2):390-398 PMID: 30046743 PMCID: PMC5974909 SCOPUS ID: 2-s2.0-85076700342 07/27/2018       3 Citations
  • Response: The coagulation laboratory monitoring of AFSTYLA single-chain FVIII concentrate. (Friedman KD, Powell JS, Bensen-Kennedy D) Haemophilia 2018 05;24(3):e129-e131 PMID: 29603512 SCOPUS ID: 2-s2.0-85044618885 04/01/2018       2 Citations
  • International comparative field study evaluating the assay performance of AFSTYLA in plasma samples at clinical hemostasis laboratories. (St Ledger K, Feussner A, Kalina U, Horn C, Metzner HJ, Bensen-Kennedy D, Blackman N, Veldman A, Stowers A, Friedman KD) J Thromb Haemost 2018 03;16(3):555-564 PMID: 29274194 SCOPUS ID: 2-s2.0-85041318196 12/24/2017       21 Citations
  • Successful kidney transplantation in a patient with congenital thrombotic thrombocytopenic purpura (Upshaw-Schulman syndrome). (Fattah H, Kumar D, George JN, Massey HD, King AL, Friedman KD, Gupta G) Transfusion 2017 12;57(12):3058-3062 PMID: 28940540 SCOPUS ID: 2-s2.0-85030266254 09/25/2017       3 Citations
  • Impact of treatment and outcomes for patients with posttransplant drug-associated thrombotic microangiopathy. (Epperla N, Hemauer K, Hamadani M, Friedman KD, Kreuziger LB) Transfusion 2017 11;57(11):2775-2781 PMID: 28836275 SCOPUS ID: 2-s2.0-85032922198 08/25/2017       11 Citations
  • Consensus on the standardization of terminology in thrombotic thrombocytopenic purpura and related thrombotic microangiopathies. (Scully M, Cataland S, Coppo P, de la Rubia J, Friedman KD, Kremer Hovinga J, Lämmle B, Matsumoto M, Pavenski K, Sadler E, Sarode R, Wu H, International Working Group for Thrombotic Thrombocytopenic Purpura) J Thromb Haemost 2017 02;15(2):312-322 PMID: 27868334 SCOPUS ID: 2-s2.0-85011711363 11/22/2016       201 Citations
  • Differentiation of pernicious anemia from thrombotic thrombocytopenic purpura: The clinical value of subtle pathologic findings. (Abbott DW, Friedman KD, Karafin MS) Transfus Apher Sci 2016 Dec;55(3):318-322 PMID: 27765664 SCOPUS ID: 2-s2.0-85004144076 10/22/2016       4 Citations
  • Effect of systemic bevacizumab in severe hereditary hemorrhagic telangiectasia associated with bleeding. (Epperla N, Kapke JT, Karafin M, Friedman KD, Foy P) Am J Hematol 2016 06;91(6):E313-4 PMID: 26994402 SCOPUS ID: 2-s2.0-84966440683 03/20/2016       14 Citations
  • Clinical and laboratory variability in a cohort of patients diagnosed with type 1 VWD in the United States. (Flood VH, Christopherson PA, Gill JC, Friedman KD, Haberichter SL, Bellissimo DB, Udani RA, Dasgupta M, Hoffmann RG, Ragni MV, Shapiro AD, Lusher JM, Lentz SR, Abshire TC, Leissinger C, Hoots WK, Manco-Johnson MJ, Gruppo RA, Boggio LN, Montgomery KT, Goodeve AC, James PD, Lillicrap D, Peake IR, Montgomery RR) Blood 2016 05 19;127(20):2481-8 PMID: 26862110 PMCID: PMC4874228 SCOPUS ID: 2-s2.0-84974556876 02/11/2016       66 Citations
  • Congenital thrombotic thrombocytopenic purpura related to a novel mutation in ADAMTS13 gene and management during pregnancy. (Epperla N, Hemauer K, Friedman KD, George JN, Foy P) Am J Hematol 2016 06;91(6):644-6 PMID: 26822222 SCOPUS ID: 2-s2.0-84967205200 01/30/2016       8 Citations
  • A computer-based model to assess costs associated with the use of factor VIII and factor IX one-stage and chromogenic activity assays. (Kitchen S, Blakemore J, Friedman KD, Hart DP, Ko RH, Perry D, Platton S, Tan-Castillo D, Young G, Luddington RJ) J Thromb Haemost 2016 Apr;14(4):757-64 PMID: 26748742 SCOPUS ID: 2-s2.0-84962657702 01/11/2016       22 Citations
  • A critical appraisal of one-stage and chromogenic assays of factor VIII activity. (Peyvandi F, Oldenburg J, Friedman KD) J Thromb Haemost 2016 Feb;14(2):248-61 PMID: 26663865 SCOPUS ID: 2-s2.0-84976209150 12/15/2015       86 Citations
  • Comparison of several von Willebrand factor (VWF) activity assays for monitoring patients undergoing treatment with VWF/FVIII concentrates: improved performance with a new modified automated method. (Hillarp A, Friedman KD, Adcock-Funk D, Tiefenbacher S, Nichols WL, Chen D, Stadler M, Schwartz BA) Haemophilia 2015 Nov;21(6):837-45 PMID: 26172561 SCOPUS ID: 2-s2.0-84946401781 07/15/2015    
  • Crucial role for the VWF A1 domain in binding to type IV collagen. (Flood VH, Schlauderaff AC, Haberichter SL, Slobodianuk TL, Jacobi PM, Bellissimo DB, Christopherson PA, Friedman KD, Gill JC, Hoffmann RG, Montgomery RR, Zimmerman Program Investigators) Blood 2015 Apr 02;125(14):2297-304 PMID: 25662333 PMCID: PMC4383803 SCOPUS ID: 2-s2.0-84926664083 02/11/2015       60 Citations
  • Allosteric activation of ADAMTS13 by von Willebrand factor. (Muia J, Zhu J, Gupta G, Haberichter SL, Friedman KD, Feys HB, Deforche L, Vanhoorelbeke K, Westfield LA, Roth R, Tolia NH, Heuser JE, Sadler JE) Proc Natl Acad Sci U S A 2014 Dec 30;111(52):18584-9 PMID: 25512528 PMCID: PMC4284596 SCOPUS ID: 2-s2.0-84924309931 12/17/2014       76 Citations
  • Comparison of anti-Xa and dilute Russell viper venom time assays in quantifying drug levels in patients on therapeutic doses of rivaroxaban. (Gosselin RC, Adcock Funk DM, Taylor JM, Francart SJ, Hawes EM, Friedman KD, Moll S) Arch Pathol Lab Med 2014 Dec;138(12):1680-4 PMID: 25427046 SCOPUS ID: 2-s2.0-84914695678 11/27/2014       33 Citations
  • Acquired von Willebrand syndrome in a child following Berlin Heart EXCOR Pediatric Ventricular Assist Device implantation: case report and concise literature review. (Costello JP, Diab YA, Philippe-Auguste M, Jones MB, Shankar V, Friedman KD, Nath DS) World J Pediatr Congenit Heart Surg 2014 Oct;5(4):592-8 PMID: 25324261 SCOPUS ID: 2-s2.0-84925884420 10/18/2014       9 Citations
  • Life-threatening bleeding in a patient with mild hemophilia A and heterozygosity for von Willebrand disease Type 2N. (Allan JN, Friedman KD, DeSancho MT) Int J Hematol 2014 Dec;100(6):602-6 PMID: 25212677 SCOPUS ID: 2-s2.0-84916641400 09/13/2014       2 Citations
  • Diagnostic challenges in patients with bleeding phenotype and von Willebrand exon 28 polymorphism p.D1472H. (Francis JC, Hui SK, Mahoney D Jr, Dietrich JE, Friedman KD, Soundar E, Srivaths LV) Haemophilia 2014 May;20(3):e211-4 PMID: 24581275 SCOPUS ID: 2-s2.0-84898920561 03/04/2014       2 Citations
  • Performance of coagulation tests in patients on therapeutic doses of rivaroxaban. A cross-sectional pharmacodynamic study based on peak and trough plasma levels. (Francart SJ, Hawes EM, Deal AM, Adcock DM, Gosselin R, Jeanneret C, Friedman KD, Moll S) Thromb Haemost 2014 Jun;111(6):1133-40 PMID: 24401946 SCOPUS ID: 2-s2.0-84901921497 01/10/2014       96 Citations
  • An optimized fluorogenic ADAMTS13 assay with increased sensitivity for the investigation of patients with thrombotic thrombocytopenic purpura. (Muia J, Gao W, Haberichter SL, Dolatshahi L, Zhu J, Westfield LA, Covill SC, Friedman KD, Sadler JE) J Thromb Haemost 2013 Aug;11(8):1511-8 PMID: 23773695 PMCID: PMC3807872 SCOPUS ID: 2-s2.0-84881590048 06/19/2013       28 Citations
  • No increase in bleeding identified in type 1 VWD subjects with D1472H sequence variation. (Flood VH, Friedman KD, Gill JC, Haberichter SL, Christopherson PA, Branchford BR, Hoffmann RG, Abshire TC, Dunn AL, Di Paola JA, Hoots WK, Brown DL, Leissinger C, Lusher JM, Ragni MV, Shapiro AD, Montgomery RR) Blood 2013 May 02;121(18):3742-4 PMID: 23520336 PMCID: PMC3643771 SCOPUS ID: 2-s2.0-84879719268 03/23/2013       21 Citations
  • Collagen binding provides a sensitive screen for variant von Willebrand disease. (Flood VH, Gill JC, Friedman KD, Christopherson PA, Jacobi PM, Hoffmann RG, Montgomery RR, Haberichter SL, Zimmerman Program Investigators) Clin Chem 2013 Apr;59(4):684-91 PMID: 23340442 PMCID: PMC3852672 SCOPUS ID: 2-s2.0-84875860574 01/24/2013       46 Citations
  • Use of purified fibrinogen concentrate for dysfibrinogenemia and importance of laboratory fibrinogen activity measurement. (Franzblau EB, Punzalan RC, Friedman KD, Roy A, Bilen O, Flood VH) Pediatr Blood Cancer 2013 Mar;60(3):500-2 PMID: 23129109 PMCID: PMC4461026 SCOPUS ID: 2-s2.0-84872441623 11/07/2012       5 Citations
  • In vitro and in vivo quality of leukoreduced apheresis platelets stored in a new platelet additive solution. (Dumont LJ, Cancelas JA, Graminske S, Friedman KD, Vassallo RR, Whitley PH, Rugg N, Dumont DF, Herschel L, Siegal AH, Szczepiorkowski ZM, Fender L, Razatos A) Transfusion 2013 May;53(5):972-80 PMID: 22882530 SCOPUS ID: 2-s2.0-84877703632 08/14/2012       24 Citations
  • Comparison of type I, type III and type VI collagen binding assays in diagnosis of von Willebrand disease. (Flood VH, Gill JC, Christopherson PA, Wren JS, Friedman KD, Haberichter SL, Hoffmann RG, Montgomery RR) J Thromb Haemost 2012 Jul;10(7):1425-32 PMID: 22507643 PMCID: PMC3809762 SCOPUS ID: 2-s2.0-84863455676 04/18/2012       36 Citations
  • Critical von Willebrand factor A1 domain residues influence type VI collagen binding. (Flood VH, Gill JC, Christopherson PA, Bellissimo DB, Friedman KD, Haberichter SL, Lentz SR, Montgomery RR) J Thromb Haemost 2012 Jul;10(7):1417-24 PMID: 22507569 PMCID: PMC3809952 SCOPUS ID: 2-s2.0-84863422773 04/18/2012       46 Citations
  • Intersection of mechanisms of type 2A VWD through defects in VWF multimerization, secretion, ADAMTS-13 susceptibility, and regulated storage. (Jacobi PM, Gill JC, Flood VH, Jakab DA, Friedman KD, Haberichter SL) Blood 2012 May 10;119(19):4543-53 PMID: 22431572 PMCID: PMC3362367 SCOPUS ID: 2-s2.0-84861068515 03/21/2012       37 Citations
  • Factor VIII/von Willebrand factor concentrate therapy for ventricular assist device-associated acquired von Willebrand disease. (Cushing M, Kawaguchi K, Friedman KD, Mark T) Transfusion 2012 Jul;52(7):1535-41 PMID: 22229973 SCOPUS ID: 2-s2.0-84863787955 01/11/2012       19 Citations
  • VWF mutations and new sequence variations identified in healthy controls are more frequent in the African-American population. (Bellissimo DB, Christopherson PA, Flood VH, Gill JC, Friedman KD, Haberichter SL, Shapiro AD, Abshire TC, Leissinger C, Hoots WK, Lusher JM, Ragni MV, Montgomery RR) Blood 2012 Mar 01;119(9):2135-40 PMID: 22197721 PMCID: PMC3311248 SCOPUS ID: 2-s2.0-84857720362 12/27/2011       69 Citations
  • Von Willebrand disease in the United States: a perspective from Wisconsin. (Flood VH, Gill JC, Friedman KD, Bellissimo DB, Haberichter SL, Montgomery RR) Semin Thromb Hemost 2011 Jul;37(5):528-34 PMID: 22102196 PMCID: PMC3807766 SCOPUS ID: 2-s2.0-81755171917 11/22/2011       22 Citations
  • Hematocrit and C-reactive protein predict treatment response times in ADAMTS13-deficient thrombotic microangiopathy. (Samia NI, Friedman KD, Gottschall JL, Raife TJ) J Clin Apher 2011;26(3):138-45 PMID: 21462238 SCOPUS ID: 2-s2.0-80052100427 04/05/2011       1 Citation
  • Therapeutic consequences for misdiagnosis of type 2N von Willebrand disease. (Gupta M, Lillicrap D, Stain AM, Friedman KD, Carcao MD) Pediatr Blood Cancer 2011 Dec 01;57(6):1081-3 PMID: 21425451 SCOPUS ID: 2-s2.0-80052680438 03/23/2011       16 Citations
  • Gain-of-function GPIb ELISA assay for VWF activity in the Zimmerman Program for the Molecular and Clinical Biology of VWD. (Flood VH, Gill JC, Morateck PA, Christopherson PA, Friedman KD, Haberichter SL, Hoffmann RG, Montgomery RR) Blood 2011 Feb 10;117(6):e67-74 PMID: 21148813 PMCID: PMC3056647 SCOPUS ID: 2-s2.0-79951469339 12/15/2010       73 Citations
  • Laboratory diagnosis of von Willebrand disease: results from a prospective and blind study in 32 laboratories worldwide using lyophilized plasmas. (Lee CA, Hubbard A, Sabin CA, Budde U, Castaman G, Favaloro EJ, Friedman KD, Federici AB, I5th-SSC Subcommittee on VWF) J Thromb Haemost 2011 Jan;9(1):220-2 PMID: 20946178 SCOPUS ID: 2-s2.0-78650959817 10/16/2010       9 Citations
  • Absent collagen binding in a VWF A3 domain mutant: utility of the VWF:CB in diagnosis of VWD. (Flood VH, Lederman CA, Wren JS, Christopherson PA, Friedman KD, Hoffmann RG, Montgomery RR) J Thromb Haemost 2010 Jun;8(6):1431-3 PMID: 20345715 PMCID: PMC3892206 SCOPUS ID: 2-s2.0-77954496769 03/30/2010       63 Citations
  • Common VWF exon 28 polymorphisms in African Americans affecting the VWF activity assay by ristocetin cofactor. (Flood VH, Gill JC, Morateck PA, Christopherson PA, Friedman KD, Haberichter SL, Branchford BR, Hoffmann RG, Abshire TC, Di Paola JA, Hoots WK, Leissinger C, Lusher JM, Ragni MV, Shapiro AD, Montgomery RR) Blood 2010 Jul 15;116(2):280-6 PMID: 20231421 PMCID: PMC2910611 SCOPUS ID: 2-s2.0-77955499972 03/17/2010       111 Citations
  • Limitations of the ristocetin cofactor assay in measurement of von Willebrand factor function. (Flood VH, Friedman KD, Gill JC, Morateck PA, Wren JS, Scott JP, Montgomery RR) J Thromb Haemost 2009 Nov;7(11):1832-9 PMID: 19694940 PMCID: PMC3825106 SCOPUS ID: 2-s2.0-70449436494 08/22/2009       59 Citations
  • Elevated procalcitonin and C-reactive protein as potential biomarkers of sepsis in a subpopulation of thrombotic microangiopathy patients. (Erickson YO, Samia NI, Bedell B, Friedman KD, Atkinson BS, Raife TJ) J Clin Apher 2009;24(4):150-4 PMID: 19591197 PMCID: PMC2750870 SCOPUS ID: 2-s2.0-69249138711 07/11/2009       12 Citations
  • Value of ADAMTS13 activity and inhibitor in the postmortem diagnosis of thrombotic thrombocytopenic purpura. (Dwyre DM, Dursteler B, Nashelsky M, Friedman KD, Raife TJ) J Clin Apher 2009;24(3):106-10 PMID: 19253359 SCOPUS ID: 2-s2.0-67449143712 03/03/2009       6 Citations
  • Type 2B von Willebrand disease associated with the release of platelet agglutinates from megakaryocytes in the bone marrow. (Slayton WB, Patel M, Sola-Visner M, Harris N, Rivers A, Montgomery RR, Friedman KD) J Pediatr Hematol Oncol 2008 Sep;30(9):708-11 PMID: 18776767 PMCID: PMC5592795 SCOPUS ID: 2-s2.0-65349161369 09/09/2008       6 Citations
  • Comparison and stability of ADAMTS13 activity in therapeutic plasma products. (Scott EA, Puca KE, Pietz BC, Duchateau BK, Friedman KD) Transfusion 2007 Jan;47(1):120-5 PMID: 17207240 SCOPUS ID: 2-s2.0-33845761943 01/09/2007       50 Citations
  • Urgent reversal of warfarin with prothrombin complex concentrate. (Lankiewicz MW, Hays J, Friedman KD, Tinkoff G, Blatt PM) J Thromb Haemost 2006 May;4(5):967-70 PMID: 16689743 SCOPUS ID: 2-s2.0-33645637952 05/13/2006       156 Citations
  • The pathogenicity of von Willebrand factor in thrombotic thrombocytopenic purpura: reconsideration of treatment with cryopoor plasma. (Raife TJ, Friedman KD, Dwyre DM) Transfusion 2006 Jan;46(1):74-9 PMID: 16398733 SCOPUS ID: 2-s2.0-33644833901 01/10/2006       21 Citations
  • Genetic mutations in von Willebrand disease identified by DHPLC and DNA sequence analysis. (Kakela JK, Friedman KD, Haberichter SL, Buchholz NP, Christopherson PA, Kroner PA, Gill JC, Montgomery RR, Bellissimo DB) Mol Genet Metab 2006 Mar;87(3):262-71 PMID: 16321553 SCOPUS ID: 2-s2.0-33644662851 12/03/2005       12 Citations
  • A prothrombotic phenotype in the Copenhagen rat strain. (Cooley BC, Chen CY, Friedman KD, Datta Y) Thromb Res 2005;115(1-2):153-7 PMID: 15567467 SCOPUS ID: 2-s2.0-9644275459 11/30/2004       1 Citation
  • Measurement of von Willebrand factor cleaving protease (ADAMTS-13): results of an international collaborative study involving 11 methods testing the same set of coded plasmas. (Tripodi A, Chantarangkul V, Böhm M, Budde U, Dong JF, Friedman KD, Galbusera M, Girma JP, Moake J, Rick ME, Studt JD, Turecek PL, Mannucci PM) J Thromb Haemost 2004 Sep;2(9):1601-9 PMID: 15333037 SCOPUS ID: 2-s2.0-19944431129 08/31/2004       86 Citations
  • Lepirudin prevents lethal effects of Shiga toxin in a canine model. (Raife T, Friedman KD, Fenwick B) Thromb Haemost 2004 Aug;92(2):387-93 PMID: 15269836 SCOPUS ID: 2-s2.0-4444327379 07/23/2004       27 Citations
  • Anti-GPVI-associated ITP: an acquired platelet disorder caused by autoantibody-mediated clearance of the GPVI/FcRgamma-chain complex from the human platelet surface. (Boylan B, Chen H, Rathore V, Paddock C, Salacz M, Friedman KD, Curtis BR, Stapleton M, Newman DK, Kahn ML, Newman PJ) Blood 2004 Sep 01;104(5):1350-5 PMID: 15150079 SCOPUS ID: 2-s2.0-4444244926 05/20/2004       122 Citations
  • Multisite study for genotyping of the factor II (prothrombin) G20210A mutation by the invader assay. (Hessner MJ, Friedman KD, Voelkerding KV, Huber S, Ryan D, Nuccie B, Ledford M) Clin Chem 2001 Nov;47(11):2048-50 PMID: 11673380 SCOPUS ID: 2-s2.0-0034771197 10/24/2001       11 Citations
  • A multi-site study for detection of the factor V (Leiden) mutation from genomic DNA using a homogeneous invader microtiter plate fluorescence resonance energy transfer (FRET) assay. (Ledford M, Friedman KD, Hessner MJ, Moehlenkamp C, Williams TM, Larson RS) J Mol Diagn 2000 May;2(2):97-104 PMID: 11272895 PMCID: PMC1906901 SCOPUS ID: 2-s2.0-0034189760 03/29/2001       34 Citations
  • Genotyping of factor V G1691A (Leiden) without the use of PCR by invasive cleavage of oligonucleotide probes. (Hessner MJ, Budish MA, Friedman KD) Clin Chem 2000 Aug;46(8 Pt 1):1051-6 PMID: 10926882 SCOPUS ID: 2-s2.0-0033869814 08/06/2000       35 Citations
  • Allelic distribution of the glycoprotein Ia (alpha2-integrin) C807T/G873A dimorphisms among caucasian venous thrombosis patients and six racial groups. (Dinauer DM, Friedman KD, Hessner MJ) Br J Haematol 1999 Dec;107(3):563-5 PMID: 10583259 SCOPUS ID: 2-s2.0-0032755030 12/03/1999       25 Citations
  • Contribution of the glycoprotein Ia 807TT, methylene tetrahydrofolate reductase 677TT and prothrombin 20210GA genotypes to prothrombotic risk among factor V 1691GA (Leiden) carriers. (Hessner MJ, Dinauer DM, Luhm RA, Endres JL, Montgomery RR, Friedman KD) Br J Haematol 1999 Jul;106(1):237-9 PMID: 10444193 SCOPUS ID: 2-s2.0-0032838868 08/12/1999       16 Citations
  • Prevalence of prothrombin G20210A, factor V G1691A (Leiden), and methylenetetrahydrofolate reductase (MTHFR) C677T in seven different populations determined by multiplex allele-specific PCR. (Hessner MJ, Luhm RA, Pearson SL, Endean DJ, Friedman KD, Montgomery RR) Thromb Haemost 1999 May;81(5):733-8 PMID: 10365746 SCOPUS ID: 2-s2.0-0032933161 06/12/1999       120 Citations
  • Phase I trial of simultaneous administration of interleukin 2 and interleukin 4 subcutaneously. (Whitehead RP, Friedman KD, Clark DA, Pagani K, Rapp L) Clin Cancer Res 1995 Oct;1(10):1145-52 PMID: 9815906 SCOPUS ID: 2-s2.0-0028871285 10/01/1995       14 Citations
  • Erythropoietin response to anaemia is not altered by surgery or recombinant human erythropoietin therapy. (Goodnough LT, Price TH, Parvin CA, Friedman KD, Vogler WR, Khan N, Sacher R, Johnston M, Wissel M, Ciavarella D) Br J Haematol 1994 Aug;87(4):695-9 PMID: 7986708 SCOPUS ID: 2-s2.0-0028017270 08/01/1994       32 Citations
  • On improving the cost-effectiveness of autologous blood transfusion practices. (Kruskall MS, Yomtovian R, Dzik WH, Friedman KD, Umlas J) Transfusion 1994 Mar;34(3):259-64 PMID: 8146902 SCOPUS ID: 2-s2.0-0028221024 03/01/1994       42 Citations
  • A phase III trial of recombinant human erythropoietin therapy in nonanemic orthopedic patients subjected to aggressive removal of blood for autologous use: dose, response, toxicity, and efficacy. (Goodnough LT, Price TH, Friedman KD, Johnston M, Ciavarella D, Khan N, Sacher R, Vogler WR, Wissel M, Abels RI) Transfusion 1994 Jan;34(1):66-71 PMID: 8273133 SCOPUS ID: 2-s2.0-0027976923 01/01/1994       112 Citations
  • An annotated bibliography on autologous transfusion. (Kruskall MS, Bodner MS, Dzik WH, Friedman KD, Gerber L, Gould SA, Gravlee G, Schoenleber DG, Yomtovian R) Transfusion 1992 Mar-Apr;32(3):286-90 PMID: 1557812 SCOPUS ID: 2-s2.0-0026823191 03/01/1992       1 Citation
  • Abnormal binding of factor VIII is linked with the substitution of glutamine for arginine 91 in von Willebrand factor in a variant form of von Willebrand disease. (Kroner PA, Friedman KD, Fahs SA, Scott JP, Montgomery RR) J Biol Chem 1991 Oct 15;266(29):19146-9 PMID: 1918030 SCOPUS ID: 2-s2.0-0026002404 10/15/1991       65 Citations
  • Enzymatic amplification of specific cDNA inserts from lambda gt11 libraries. (Friedman KD, Rosen NL, Newman PJ, Montgomery RR) Nucleic Acids Res 1988 Sep 12;16(17):8718 PMID: 2843825 PMCID: PMC338596 SCOPUS ID: 2-s2.0-0023758387 09/12/1988       43 Citations
  • Thrombolytic therapy with tissue plasminogen activator or streptokinase induces transient thrombin activity. (Owen J, Friedman KD, Grossman BA, Wilkins C, Berke AD, Powers ER) Blood 1988 Aug;72(2):616-20 PMID: 3135862 SCOPUS ID: 2-s2.0-0023690819 08/01/1988       179 Citations
  • Protein C deficiency. A cause of unusual or unexplained thrombosis. (Tollefson DF, Friedman KD, Marlar RA, Bandyk DF, Towne JB) Arch Surg 1988 Jul;123(7):881-4 PMID: 3382355 SCOPUS ID: 2-s2.0-0023770902 07/01/1988       27 Citations
  • Quantitation of fragment X formation during thrombolytic therapy with streptokinase and tissue plasminogen activator. (Owen J, Friedman KD, Grossman BA, Wilkins C, Berke AD, Powers ER) J Clin Invest 1987 Jun;79(6):1642-7 PMID: 2953761 PMCID: PMC424490 SCOPUS ID: 2-s2.0-0023195775 06/01/1987       38 Citations
  • Heparin cofactor activity and antithrombin III antigen levels in preeclampsia. (Friedman KD, Borok Z, Owen J) Thromb Res 1986 Aug 15;43(4):409-16 PMID: 3764801 SCOPUS ID: 2-s2.0-0022480009 08/15/1986       5 Citations
  • Last update: 08/28/2021