Faculty Collaboration Database

Ten-year experience with surgical unroofing of anomalous aortic origin of a coronary artery from the opposite sinus with an interarterial course. J Thorac Cardiovasc Surg 2011 Nov;142(5):1046-51

Date

03/29/2011

Pubmed ID

21439578

DOI

10.1016/j.jtcvs.2011.02.004

Scopus ID

2-s2.0-80055009618 (requires institutional sign-in at Scopus site)   101 Citations

Abstract

BACKGROUND: Anomalous aortic origin of a coronary artery from the opposite sinus with an intramural course between the great arteries (AAOCA) is associated with ischemia and sudden cardiac death in children, and surgical unroofing has been used to alleviate that risk.

METHODS: The cardiology database was reviewed to identify all patients with AAOCA who underwent surgical unroofing 10 years.

RESULTS: From March 1999 to September 2009, 27 patients with a mean age of 12.6 ± 3.5 years (range, 4-20 years) had surgical unroofing of AAOCA of the left coronary from the right sinus (left AAOCA, 7/27, 26%) or of the right coronary from the left sinus (right AAOCA, 20/27, 74%). Of these, 26 had diagnoses made by transthoracic echocardiography. Symptoms included resuscitated sudden cardiac death in 3, syncope in 8, and chest pain in 4. No symptoms were present in 12 cases of serendipitous diagnosis. Unroofing of the intramural portion was successfully performed in all cases. A slitlike coronary orifice was described at surgical inspection in 12 patients, 7 of whom had right AAOCA and no symptoms. All patients after unroofing have patent coronary flow by Doppler and normal echocardiography and exercise treadmill testing at mean follow-up of 1.8 years. None have activity restrictions.

CONCLUSIONS: AAOCA is frequently characterized by an intramural course, which can be reliably identified by echocardiography. This form can be safely repaired by unroofing the intramural segment without early morbidity. Symptoms of possible ischemia are common but not always correlated with coronary ostial findings at surgery.

Author List

Frommelt PC, Sheridan DC, Berger S, Frommelt MA, Tweddell JS

Authors

Peter C. Frommelt MD Adjunct Professor in the Pediatrics department at Medical College of Wisconsin
Michele Ann Frommelt MD Adjunct Professor in the Pediatrics department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adolescent
Angina Pectoris
Asymptomatic Diseases
Cardiac Surgical Procedures
Cardiopulmonary Resuscitation
Child
Child, Preschool
Coronary Circulation
Coronary Sinus
Coronary Vessel Anomalies
Death, Sudden, Cardiac
Echocardiography, Doppler
Exercise Test
Female
Humans
Male
Myocardial Ischemia
Syncope
Time Factors
Treatment Outcome
Vascular Patency
Wisconsin
Young Adult