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Impact of induction regimens intensity and allogeneic stem cell transplantation on survival of patients with Philadelphia chromosome-positive acute lymphoblastic leukemia: A multi-institutional study. Am J Hematol 2024 Dec;99(12):2388-2391

Date

09/10/2024

Pubmed ID

39253997

DOI

10.1002/ajh.27475

Scopus ID

2-s2.0-85203436363 (requires institutional sign-in at Scopus site)   2 Citations

Abstract

Intensive chemotherapy (IC) combination with second- or third-generation TKI improves survival compared to non-IC with first-generation TKI. Allo-HCT was suggestive of improving RFS/OS after propensity score matching and multivariable analysis.

Author List

Badar T, Narra R, Mims AS, Heckman MG, Shallis RM, Fahad S, Hunter C, Kota V, Othman TA, Jonas B, Desai S, de Camargo Correia GS, Patel A, DuVall AS, Palmisiano N, Curran E, Omer Z, Advani A, Atallah E, Litzow M

Authors

Ehab L. Atallah MD Professor in the Medicine department at Medical College of Wisconsin
Ravi Kishore Narra MD Assistant Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adolescent
Adult
Aged
Allografts
Antineoplastic Combined Chemotherapy Protocols
Female
Hematopoietic Stem Cell Transplantation
Humans
Induction Chemotherapy
Male
Middle Aged
Philadelphia Chromosome
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Protein Kinase Inhibitors
Retrospective Studies
Survival Rate
Transplantation, Homologous
Young Adult