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Naming outcome after left or right temporal lobectomy in patients with bilateral language representation by Wada testing. Epilepsy Behav 2013 Jul;28(1):95-8

Date

05/22/2013

Pubmed ID

23688676

Pubmed Central ID

PMC3673014

DOI

10.1016/j.yebeh.2013.04.006

Scopus ID

2-s2.0-84878169164   7 Citations

Abstract

OBJECTIVE: This study aimed to examine language outcome after left or right anterior temporal lobectomy (ATL) in patients with epilepsy with bilateral language representation on intracarotid sodium amobarbital (Wada) testing.

METHODS: Twenty-two patients with epilepsy with bilateral language (Wada laterality index between -50 and 50) underwent right ATL (RATL, n=10) or left ATL (LATL, n=12). All the patients were administered the Boston Naming Test preoperatively and six months postoperatively.

RESULTS: Left anterior temporal lobectomy patients showed greater postoperative naming decline than RATL patients. Group differences were also observed on subtests of the Wada test. Performance on the Wada naming and comprehension subtests was better in the nonsurgical hemisphere than in the surgical hemisphere in the RATL group, but there was no difference between the nonsurgical and the surgical hemisphere naming and comprehension performance in the LATL group.

CONCLUSIONS: Left anterior temporal lobectomy patients with bilateral language are at greater risk for naming decline than RATL patients with bilateral language. This difference may be due to relatively better naming and comprehension abilities in the nonsurgical hemisphere in the RATL group.

Author List

Janecek JK, Winstanley FS, Sabsevitz DS, Raghavan M, Mueller W, Binder JR, Swanson SJ

Authors

Jeffrey R. Binder MD Professor in the Neurology department at Medical College of Wisconsin
Julie K. Janecek PhD Associate Professor in the Neurology department at Medical College of Wisconsin
Wade M. Mueller MD Professor in the Neurosurgery department at Medical College of Wisconsin
Manoj Raghavan MD, PhD Professor in the Neurology department at Medical College of Wisconsin
Sara J. Swanson PhD Chief, Professor in the Neurology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adult
Amobarbital
Anterior Temporal Lobectomy
Epilepsy, Temporal Lobe
Female
Functional Laterality
Humans
Language Disorders
Language Tests
Male
Middle Aged
Names
Neuropsychological Tests
Retrospective Studies
Young Adult