Faculty Collaboration Database

Controlled-release oxycodone for the management of pediatric postoperative pain. J Pain Symptom Manage 2004 Apr;27(4):379-86

Date

04/29/2004

Pubmed ID

15112683

DOI

10.1016/j.jpainsymman.2003.08.007

Scopus ID

2-s2.0-1642603504 (requires institutional sign-in at Scopus site)   37 Citations

Abstract

Studies addressing pain management after pediatric spinal fusion surgery have focused on the use of patient-controlled or epidural analgesia during the immediate postoperative period. Controlled-release (CR) analgesics have been found to be safe and effective in adults. The purpose of this study was to describe the use of oxycodone-CR in pediatric patients after the immediate postoperative period. A retrospective chart review of 62 postoperative spinal fusion patients (10-19 years) was conducted. The mean initial oxycodone-CR dose was 1.24 mg/kg/day. The mean ratio of conversion from parenteral morphine equivalents to oxycodone-CR was 1:1. Mean pain scores decreased from 4.2/10 to 3.7/10 with the transition to oxycodone-CR. Common side effects included dizziness, constipation, and nausea. Oxycodone-CR was used for an average of 13.3 days, which included an average wean time of 6 days. Results of this study demonstrate safe and effective use of oxycodone-CR in the pediatric spinal fusion population.

Author List

Czarnecki ML, Jandrisevits MD, Theiler SC, Huth MM, Weisman SJ

Authors

Matthew Jandrisevits PhD Assistant Professor in the Psychiatry and Behavioral Medicine department at Medical College of Wisconsin
Steven J. Weisman MD Professor in the Anesthesiology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adolescent
Analgesics, Opioid
Child
Delayed-Action Preparations
Female
Humans
Male
Oxycodone
Pain, Postoperative
Retrospective Studies
Treatment Outcome