Faculty Collaboration Database

Effect of a baking soda-peroxide dentifrice on post-surgical wound healing. Am J Dent 1995 Jun;8(3):125-7

Date

06/01/1995

Pubmed ID

8599587

Scopus ID

2-s2.0-0029312986 (requires institutional sign-in at Scopus site)   3 Citations

Abstract

PURPOSE: To investigate the effect of a baking soda-hydrogen peroxide (0.75%) dentifrice on wound healing, plaque formation, gingival inflammation, patient comfort, probing depth, and clinical attachment level following gingival flap surgery.

MATERIALS AND METHODS: A randomized, double-blind crossover study involving 25 patients requiring bilateral maxillary gingival flap surgery was completed. The effects of twice daily brushing with a baking soda-hydrogen peroxide dentifrice (Mentadent) or a placebo dentifrice (Crest) were observed over a 28-day post-surgical period. Gingival Index (GI), plaque index (PI), probing depth (PD), clinical attachment level (CAL) and gingival bleeding index (BI) were recorded pre-surgically and at day 28 for each surgical sextant. At days 7 and 14, soft tissue appearance/wound healing (STA) was assessed based on color and edema, PIs were determined and patient comfort was ascertained by report.

RESULTS: Post-surgical wound healing was statistically significantly improved at day 7 with the trend continuing to day 14 when Mentadent dentifrice was used as compared to Crest dentifrice. However, there was no statistical difference in the PI values between the test and control dentifrice throughout the study. Use of Mentadent may be an effective aid in the early phase of healing following gingival flap surgery.

Author List

Dentino AR, Ciancio SG, Bessinger M, Mather MA, Cancro L, Fischman S

Author

Andrew Dentino BS,DDS,PhD Professor & Program Director of Periodontics in the Surgical Sciences department at Marquette University

MESH terms used to index this publication - Major topics in bold

Adult
Aged
Anti-Infective Agents, Local
Cross-Over Studies
Dental Plaque
Dental Plaque Index
Dentifrices
Double-Blind Method
Edema
Female
Gingivitis
Gingivoplasty
Humans
Hydrogen Peroxide
Male
Middle Aged
Pain, Postoperative
Periodontal Index
Postoperative Period
Sodium Bicarbonate
Surgical Flaps
Wound Healing