Age-related changes in prefrontal white matter volume across adolescence. Neuroreport 2006 Sep 18;17(13):1427-31
Date
08/26/2006Pubmed ID
16932152Pubmed Central ID
PMC2270704DOI
10.1097/01.wnr.0000233099.97784.45Scopus ID
2-s2.0-33748067285 (requires institutional sign-in at Scopus site) 39 CitationsAbstract
Past research has suggested that white matter volume increases from childhood to adulthood; however, during adolescence, there is somewhat limited data to support this finding. In the present study, 65 typically developing adolescents underwent structural magnetic resonance imaging. Using magnetic resonance imaging, prefrontal white matter volumes were examined in relation to adolescent age and sex. Surprisingly, results suggested that prefrontal white matter volume decreased during late adolescence, particularly among the female sex. These findings are inconsistent with past research and suggest that perhaps some developmental processes in late adolescence are not yet fully explained. Possible methodological contributions and implications for the current findings are discussed.
Author List
Nagel BJ, Medina KL, Yoshii J, Schweinsburg AD, Moadab I, Tapert SFAuthor
Krista Lisdahl PhD Assistant Professor in the Psychology department at University of Wisconsin - MilwaukeeMESH terms used to index this publication - Major topics in bold
AdolescentAge Factors
Aging
Brain Mapping
Child
Female
Humans
Magnetic Resonance Imaging
Male
Prefrontal Cortex
