Faculty Collaboration Database

Pancytopenia responding to treatment of hyperthyroidism: a clinical case and review of the literature. Clin Lab Haematol 2002 Dec;24(6):385-7

Date

11/28/2002

Pubmed ID

12452820

DOI

10.1046/j.1365-2257.2002.00460.x

Scopus ID

2-s2.0-0036887292 (requires institutional sign-in at Scopus site)   20 Citations

Abstract

A 46-year-old-man received high dose chemotherapy and an autologous stem-cell transplant for multiple plasmacytoma. He had a prolonged period of pancytopenia post-transplantation, which was thought to be due to a suboptimal dose of transplanted stem cells in combination with the effects of interferon therapy and an altered bone marrow microenvironment. Twenty-eight months after the transplant he was found to be hyperthyroid. Anti-thyroid therapy has led to a sustained improvement in his pancytopenia.

Author List

Shaw B, Mehta AB

Author

Bronwen E. Shaw MBChB, PhD Center Director, Professor in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Antineoplastic Agents, Alkylating
Antineoplastic Combined Chemotherapy Protocols
Back Pain
Carbimazole
Cyclophosphamide
Doxorubicin
Graves Disease
Gynecomastia
Humans
Male
Melphalan
Methylprednisolone
Middle Aged
Multiple Myeloma
Pancytopenia
Peripheral Blood Stem Cell Transplantation
Ribs
Spinal Neoplasms
Thoracic Vertebrae
Transplantation Conditioning
Transplantation, Autologous
Vincristine