Faculty Collaboration Database

Peak force and maximal shortening velocity of soleus fibers after non-weight-bearing and resistance exercise. J Appl Physiol (1985) 1997 Jan;82(1):189-95

Date

01/01/1997

Pubmed ID

9029215

DOI

10.1152/jappl.1997.82.1.189

Scopus ID

2-s2.0-0031034102 (requires institutional sign-in at Scopus site)   24 Citations

Abstract

This study examined the effectiveness of resistance exercise as a countermeasure to non-weight-bearing-induced alterations in the absolute peak force, normalized peak force (force/fiber cross-sectional area), peak stiffness, and maximal shortening velocity (Vo) of single permeabilized type I soleus muscle fibers. Adult rats were subjected to the following treatments: normal weight bearing (WB), non-weight bearing (NWB), or NWB with exercise treatments (NWB+Ex). The hindlimbs of the NWB and NWB+Ex rats were suspended for 14 days via tail harnesses. Four times each day, the NWB+Ex rats were removed from suspension and performed 10 climbs (approximately 15 cm each) up a steep grid with a 500-g mass (approximately 1.5 times body mass) attached to their tail harness. NWB was associated with significant reductions in type I fiber diameter, absolute force, normalized force, and stiffness. Exercise treatments during NWB attenuated the decline in fiber diameter and absolute force by almost 60% while maintaining normalized force and stiffness at WB levels. Type I fiber Vo increased by 33% with NWB and remained at this elevated level despite the exercise treatments. We conclude that in comparison to intermittent weight bearing only (J.J. Widrick, J.J. Bangart, M. Karhanek, and R.H. Fitts. J. Appl. Physiol. 80: 981-987, 1996), resistance exercise was more effective in attenuating alterations in type I soleus fiber absolute force, normalized force, and stiffness but was less effective in restoring type I fiber Vo to WB levels.

Author List

Widrick JJ, Fitts RH

Author

Robert Fitts PhD Professor in the Biological Sciences department at Marquette University

MESH terms used to index this publication - Major topics in bold

Animals
Hindlimb
Male
Muscle Fibers, Skeletal
Muscle, Skeletal
Physical Conditioning, Animal
Rats
Rats, Sprague-Dawley