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Medical College of Wisconsin

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Robert Fitts PhD

Professor

Institution: Marquette University
Department: Biological Sciences

Member of the Cardiovascular Center

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Publications (119)

Contractility of Induced Pluripotent Stem Cell-Cardiomyocytes With an MYH6 Head Domain Variant Associated With Hypoplastic Left Heart Syndrome. (Kim MS, Fleres B, Lovett J, Anfinson M, Samudrala SSK, Kelly LJ, Teigen LE, Cavanaugh M, Marquez M, Geurts AM, Lough JW, Mitchell ME, Fitts RH, Tomita-Mitchell A) Front Cell Dev Biol 2020;8:440 PMID: 32656206 PMCID: PMC7324479 SCOPUS ID: 2-s2.0-85087475806 07/14/2020 26 Citations

Ca²⁺ dependency of limb muscle fiber contractile mechanics in young and older adults. (Teigen LE, Sundberg CW, Kelly LJ, Hunter SK, Fitts RH) Am J Physiol Cell Physiol 2020 Jun 01;318(6):C1238-C1251 PMID: 32348175 PMCID: PMC7311743 SCOPUS ID: 2-s2.0-85085961827 04/30/2020 13 Citations

Cardiomyocyte slowly activating delayed rectifier potassium channel: regulation by exercise and β-adrenergic signaling. (Wang X, Fitts RH) J Appl Physiol (1985) 2020 May 01;128(5):1177-1185 PMID: 32240024 SCOPUS ID: 2-s2.0-85084167515 04/03/2020 8 Citations

Bioenergetic basis of skeletal muscle fatigue. (Sundberg CW, Fitts RH) Curr Opin Physiol 2019 Aug;10:118-127 PMID: 31342000 PMCID: PMC6656370 SCOPUS ID: 2-s2.0-85066976606 07/26/2019 56 Citations

Bioenergetic basis for the increased fatigability with ageing. (Sundberg CW, Prost RW, Fitts RH, Hunter SK) J Physiol 2019 Oct;597(19):4943-4957 PMID: 31018011 PMCID: PMC7205544 SCOPUS ID: 2-s2.0-85066079628 04/25/2019 40 Citations

Effects of regular exercise on ventricular myocyte biomechanics and K_ATP channel function. (Wang X, Fitts RH) Am J Physiol Heart Circ Physiol 2018 Oct 01;315(4):H885-H896 PMID: 30074836 SCOPUS ID: 2-s2.0-85053835914 08/04/2018 9 Citations

Effects of elevated H⁺ and P_i on the contractile mechanics of skeletal muscle fibres from young and old men: implications for muscle fatigue in humans. (Sundberg CW, Hunter SK, Trappe SW, Smith CS, Fitts RH) J Physiol 2018 Sep;596(17):3993-4015 PMID: 29806714 PMCID: PMC6117549 SCOPUS ID: 2-s2.0-85052527500 05/29/2018 60 Citations

Ventricular action potential adaptation to regular exercise: role of β-adrenergic and K_ATP channel function. (Wang X, Fitts RH) J Appl Physiol (1985) 2017 Aug 01;123(2):285-296 PMID: 28522761 SCOPUS ID: 2-s2.0-85026626655 05/20/2017 14 Citations

Skeletal muscle PGC-1β signaling is sufficient to drive an endurance exercise phenotype and to counteract components of detraining in mice. (Lee S, Leone TC, Rogosa L, Rumsey J, Ayala J, Coen PM, Fitts RH, Vega RB, Kelly DP) Am J Physiol Endocrinol Metab 2017 May 01;312(5):E394-E406 PMID: 28270443 PMCID: PMC5451529 SCOPUS ID: 2-s2.0-85018422366 03/09/2017 13 Citations

Calsequestrin depolymerizes when calcium is depleted in the sarcoplasmic reticulum of working muscle. (Manno C, Figueroa LC, Gillespie D, Fitts R, Kang C, Franzini-Armstrong C, Rios E) Proc Natl Acad Sci U S A 2017 Jan 24;114(4):E638-E647 PMID: 28069951 PMCID: PMC5278470 SCOPUS ID: 2-s2.0-85010874843 01/11/2017 51 Citations

Muscle Fatigue from the Perspective of a Single Crossbridge. (Debold EP, Fitts RH, Sundberg CW, Nosek TM) Med Sci Sports Exerc 2016 Nov;48(11):2270-2280 PMID: 27434086 SCOPUS ID: 2-s2.0-84978708650 10/19/2016 69 Citations

The Role of Acidosis in Fatigue: Pro Perspective. (Fitts RH) Med Sci Sports Exerc 2016 Nov;48(11):2335-2338 PMID: 27755382 SCOPUS ID: 2-s2.0-84992047628 10/19/2016 84 Citations

Treatment with ActRIIB-mFc Produces Myofiber Growth and Improves Lifespan in the Acta1 H40Y Murine Model of Nemaline Myopathy. (Tinklenberg J, Meng H, Yang L, Liu F, Hoffmann RG, Dasgupta M, Allen KP, Beggs AH, Hardeman EC, Pearsall RS, Fitts RH, Lawlor MW) Am J Pathol 2016 Jun;186(6):1568-81 PMID: 27102768 PMCID: PMC4901141 SCOPUS ID: 2-s2.0-84969848977 04/23/2016 22 Citations

Weekly versus monthly testosterone administration on fast and slow skeletal muscle fibers in older adult males. (Fitts RH, Peters JR, Dillon EL, Durham WJ, Sheffield-Moore M, Urban RJ) J Clin Endocrinol Metab 2015 Feb;100(2):E223-31 PMID: 25387260 PMCID: PMC4318887 SCOPUS ID: 2-s2.0-84928327082 11/12/2014 22 Citations

Phosphate and acidosis act synergistically to depress peak power in rat muscle fibers. (Nelson CR, Debold EP, Fitts RH) Am J Physiol Cell Physiol 2014 Nov 15;307(10):C939-50 PMID: 25186012 PMCID: PMC4233260 SCOPUS ID: 2-s2.0-84922480868 09/05/2014 43 Citations

Effects of low cell pH and elevated inorganic phosphate on the pCa-force relationship in single muscle fibers at near-physiological temperatures. (Nelson CR, Fitts RH) Am J Physiol Cell Physiol 2014 Apr 01;306(7):C670-8 PMID: 24452378 SCOPUS ID: 2-s2.0-84900546685 01/24/2014 53 Citations

Effects of prolonged space flight on human skeletal muscle enzyme and substrate profiles. (Fitts RH, Colloton PA, Trappe SW, Costill DL, Bain JL, Riley DA) J Appl Physiol (1985) 2013 Sep 01;115(5):667-79 PMID: 23766501 SCOPUS ID: 2-s2.0-84883595710 06/15/2013 46 Citations

Confocal imaging of transmembrane voltage by SEER of di-8-ANEPPS. (Manno C, Figueroa L, Fitts R, Ríos E) J Gen Physiol 2013 Mar;141(3):371-87 PMID: 23440278 PMCID: PMC3581694 SCOPUS ID: 2-s2.0-84874680227 02/27/2013 16 Citations

Skeletal muscle fatigue. (Kent-Braun JA, Fitts RH, Christie A) Compr Physiol 2012 Apr;2(2):997-1044 PMID: 23798294 SCOPUS ID: 2-s2.0-84862174515 04/01/2012 150 Citations

New insights on sarcoplasmic reticulum calcium regulation in muscle fatigue. (Fitts RH) J Appl Physiol (1985) 2011 Aug;111(2):345-6 PMID: 21680881 SCOPUS ID: 2-s2.0-80051773582 06/18/2011 9 Citations

Prolonged space flight-induced alterations in the structure and function of human skeletal muscle fibres. (Fitts RH, Trappe SW, Costill DL, Gallagher PM, Creer AC, Colloton PA, Peters JR, Romatowski JG, Bain JL, Riley DA) J Physiol 2010 Sep 15;588(Pt 18):3567-92 PMID: 20660569 PMCID: PMC2988519 SCOPUS ID: 2-s2.0-77956742956 07/28/2010 273 Citations

Effect of recombinant growth hormone replacement in a growth hormone deficient subject recovering from mild traumatic brain injury: A case report. (Bhagia V, Gilkison C, Fitts RH, Zgaljardic DJ, High WM Jr, Masel BE, Urban RJ, Mossberg KA) Brain Inj 2010;24(3):560-7 PMID: 20184413 SCOPUS ID: 2-s2.0-77649139324 02/27/2010 28 Citations

Exercise in space: human skeletal muscle after 6 months aboard the International Space Station. (Trappe S, Costill D, Gallagher P, Creer A, Peters JR, Evans H, Riley DA, Fitts RH) J Appl Physiol (1985) 2009 Apr;106(4):1159-68 PMID: 19150852 SCOPUS ID: 2-s2.0-66149124537 01/20/2009 360 Citations

The cross-bridge cycle and skeletal muscle fatigue. (Fitts RH) J Appl Physiol (1985) 2008 Feb;104(2):551-8 PMID: 18162480 SCOPUS ID: 2-s2.0-38949101451 12/29/2007 290 Citations

The deleterious effects of bed rest on human skeletal muscle fibers are exacerbated by hypercortisolemia and ameliorated by dietary supplementation. (Fitts RH, Romatowski JG, Peters JR, Paddon-Jones D, Wolfe RR, Ferrando AA) Am J Physiol Cell Physiol 2007 Jul;293(1):C313-20 PMID: 17409123 SCOPUS ID: 2-s2.0-34547101459 04/06/2007 90 Citations

Low cell pH depresses peak power in rat skeletal muscle fibres at both 30 degrees C and 15 degrees C: implications for muscle fatigue. (Knuth ST, Dave H, Peters JR, Fitts RH) J Physiol 2006 Sep 15;575(Pt 3):887-99 PMID: 16809373 PMCID: PMC1995695 SCOPUS ID: 2-s2.0-33748314631 07/01/2006 93 Citations

Cardiorespiratory responses to physical work during and following 17 days of bed rest and spaceflight. (Trappe T, Trappe S, Lee G, Widrick J, Fitts R, Costill D) J Appl Physiol (1985) 2006 Mar;100(3):951-7 PMID: 16306254 SCOPUS ID: 2-s2.0-33645798629 11/25/2005 73 Citations

The depressive effect of Pi on the force-pCa relationship in skinned single muscle fibers is temperature dependent. (Debold EP, Romatowski J, Fitts RH) Am J Physiol Cell Physiol 2006 Apr;290(4):C1041-50 PMID: 16282195 SCOPUS ID: 2-s2.0-33646385633 11/12/2005 69 Citations

Skeletal muscle fiber atrophy: altered thin filament density changes slow fiber force and shortening velocity. (Riley DA, Bain JL, Romatowski JG, Fitts RH) Am J Physiol Cell Physiol 2005 Feb;288(2):C360-5 PMID: 15469952 SCOPUS ID: 2-s2.0-12144262858 10/08/2004 42 Citations

Contractile responses of the rat gastrocnemius and soleus muscles to isotonic resistance exercise. (Norenberg KM, Fitts RH) J Appl Physiol (1985) 2004 Dec;97(6):2322-32 PMID: 15322071 SCOPUS ID: 2-s2.0-9244238161 08/24/2004 21 Citations

Passive stretch inhibits central corelike lesion formation in the soleus muscles of hindlimb-suspended unloaded rats. (Baewer DV, Hoffman M, Romatowski JG, Bain JL, Fitts RH, Riley DA) J Appl Physiol (1985) 2004 Sep;97(3):930-4 PMID: 15133001 SCOPUS ID: 2-s2.0-4344588783 05/11/2004 23 Citations

Fiber type and temperature dependence of inorganic phosphate: implications for fatigue. (Debold EP, Dave H, Fitts RH) Am J Physiol Cell Physiol 2004 Sep;287(3):C673-81 PMID: 15128502 SCOPUS ID: 2-s2.0-4143078057 05/07/2004 88 Citations

Hindlimb unloading-induced muscle atrophy and loss of function: protective effect of isometric exercise. (Hurst JE, Fitts RH) J Appl Physiol (1985) 2003 Oct;95(4):1405-17 PMID: 12819219 SCOPUS ID: 2-s2.0-0141567924 06/24/2003 53 Citations

Effects of regular exercise training on skeletal muscle contractile function. (Fitts RH) Am J Phys Med Rehabil 2003 Apr;82(4):320-31 PMID: 12649660 SCOPUS ID: 2-s2.0-0037380676 03/22/2003 43 Citations

Unilateral lower limb suspension does not mimic bed rest or spaceflight effects on human muscle fiber function. (Widrick JJ, Trappe SW, Romatowski JG, Riley DA, Costill DL, Fitts RH) J Appl Physiol (1985) 2002 Jul;93(1):354-60 PMID: 12070225 SCOPUS ID: 2-s2.0-0035986076 06/19/2002 40 Citations

Thin filament diversity and physiological properties of fast and slow fiber types in astronaut leg muscles. (Riley DA, Bain JL, Thompson JL, Fitts RH, Widrick JJ, Trappe SW, Trappe TA, Costill DL) J Appl Physiol (1985) 2002 Feb;92(2):817-25 PMID: 11796697 SCOPUS ID: 2-s2.0-0036089917 01/18/2002 39 Citations

Functional and structural adaptations of skeletal muscle to microgravity. (Fitts RH, Riley DR, Widrick JJ) J Exp Biol 2001 Sep;204(Pt 18):3201-8 PMID: 11581335 SCOPUS ID: 2-s2.0-0035745756 10/03/2001 382 Citations

Effect of spaceflight on the isotonic contractile properties of single skeletal muscle fibers in the rhesus monkey. (Fitts RH, Romatowski JG, Blaser C, De La Cruz L, Gettelman GJ, Widrick JJ) J Gravit Physiol 2000 Jan;7(1):S53-4 PMID: 11543460 SCOPUS ID: 2-s2.0-0033642184 09/07/2001 10 Citations

Effect of spaceflight on the maximal shortening velocity, morphology, and enzyme profile of fast- and slow-twitch skeletal muscle fibers in rhesus monkeys. (Fitts RH, Romatowski JG, De La Cruz L, Widrick JJ, Desplanches D) J Gravit Physiol 2000 Jan;7(1):S37-8 PMID: 11543454 SCOPUS ID: 2-s2.0-0033650434 09/07/2001 9 Citations

Comparison of a space shuttle flight (STS-78) and bed rest on human muscle function. (Trappe SW, Trappe TA, Lee GA, Widrick JJ, Costill DL, Fitts RH) J Appl Physiol (1985) 2001 Jul;91(1):57-64 PMID: 11408413 SCOPUS ID: 2-s2.0-0034971330 06/16/2001 82 Citations

Functional properties of slow and fast gastrocnemius muscle fibers after a 17-day spaceflight. (Widrick JJ, Romatowski JG, Norenberg KM, Knuth ST, Bain JL, Riley DA, Trappe SW, Trappe TA, Costill DL, Fitts RH) J Appl Physiol (1985) 2001 Jun;90(6):2203-11 PMID: 11356784 SCOPUS ID: 2-s2.0-0034997672 05/18/2001 64 Citations

Fiber-type susceptibility to eccentric contraction-induced damage of hindlimb-unloaded rat AL muscles. (Vijayan K, Thompson JL, Norenberg KM, Fitts RH, Riley DA) J Appl Physiol (1985) 2001 Mar;90(3):770-6 PMID: 11181582 SCOPUS ID: 2-s2.0-0035105723 02/22/2001 94 Citations

Effects of depolarization and low intracellular pH on charge movement currents of frog skeletal muscle fibers. (Balog EM, Fitts RH) J Appl Physiol (1985) 2001 Jan;90(1):228-34 PMID: 11133914 SCOPUS ID: 2-s2.0-0035170185 01/03/2001 17 Citations

Spaceflight effects on single skeletal muscle fiber function in the rhesus monkey. (Fitts RH, Desplanches D, Romatowski JG, Widrick JJ) Am J Physiol Regul Integr Comp Physiol 2000 Nov;279(5):R1546-57 PMID: 11049835 SCOPUS ID: 2-s2.0-0033668502 10/26/2000 26 Citations

Physiology of a microgravity environment invited review: microgravity and skeletal muscle. (Fitts RH, Riley DR, Widrick JJ) J Appl Physiol (1985) 2000 Aug;89(2):823-39 PMID: 10926670 SCOPUS ID: 2-s2.0-0033883216 08/05/2000 490 Citations

Decreased thin filament density and length in human atrophic soleus muscle fibers after spaceflight. (Riley DA, Bain JL, Thompson JL, Fitts RH, Widrick JJ, Trappe SW, Trappe TA, Costill DL) J Appl Physiol (1985) 2000 Feb;88(2):567-72 PMID: 10658024 SCOPUS ID: 2-s2.0-0033974488 02/05/2000 103 Citations

Substrate profile in rat soleus muscle fibers after hindlimb unloading and fatigue. (Grichko VP, Heywood-Cooksey A, Kidd KR, Fitts RH) J Appl Physiol (1985) 2000 Feb;88(2):473-8 PMID: 10658013 SCOPUS ID: 2-s2.0-0033977433 02/05/2000 64 Citations

Effect of a 17 day spaceflight on contractile properties of human soleus muscle fibres. (Widrick JJ, Knuth ST, Norenberg KM, Romatowski JG, Bain JL, Riley DA, Karhanek M, Trappe SW, Trappe TA, Costill DL, Fitts RH) J Physiol 1999 May 01;516 ( Pt 3)(Pt 3):915-30 PMID: 10200437 PMCID: PMC2269300 SCOPUS ID: 2-s2.0-0033135334 04/14/1999 208 Citations

Five myofibrillar lesion types in eccentrically challenged, unloaded rat adductor longus muscle--a test model. (Thompson JL, Balog EM, Fitts RH, Riley DA) Anat Rec 1999 Jan;254(1):39-52 PMID: 9892416 SCOPUS ID: 2-s2.0-0032956552 01/19/1999 44 Citations

Substrate and enzyme profile of fast and slow skeletal muscle fibers in rhesus monkeys. (Grichko VP, Gettelman GJ, Widrick JJ, Fitts RH) J Appl Physiol (1985) 1999 Jan;86(1):335-40 PMID: 9887148 SCOPUS ID: 2-s2.0-0032958710 01/14/1999 8 Citations

Force-velocity-power and force-pCa relationships of human soleus fibers after 17 days of bed rest. (Widrick JJ, Norenberg KM, Romatowski JG, Blaser CA, Karhanek M, Sherwood J, Trappe SW, Trappe TA, Costill DL, Fitts RH) J Appl Physiol (1985) 1998 Nov;85(5):1949-56 PMID: 9804603 SCOPUS ID: 2-s2.0-15644378975 11/06/1998 59 Citations

Disproportionate loss of thin filaments in human soleus muscle after 17-day bed rest. (Riley DA, Bain JL, Thompson JL, Fitts RH, Widrick JJ, Trappe SW, Trappe TA, Costill DL) Muscle Nerve 1998 Oct;21(10):1280-9 PMID: 9736056 SCOPUS ID: 2-s2.0-0031784365 09/15/1998 82 Citations

Velocity, force, power, and Ca2+ sensitivity of fast and slow monkey skeletal muscle fibers. (Fitts RH, Bodine SC, Romatowski JG, Widrick JJ) J Appl Physiol (1985) 1998 May;84(5):1776-87 PMID: 9572830 SCOPUS ID: 2-s2.0-0031968841 06/06/1998 33 Citations

Effect of 17 days of bed rest on peak isometric force and unloaded shortening velocity of human soleus fibers. (Widrick JJ, Romatowski JG, Bain JL, Trappe SW, Trappe TA, Thompson JL, Costill DL, Riley DA, Fitts RH) Am J Physiol 1997 Nov;273(5 Pt 1):C1690-9 PMID: 9374656 SCOPUS ID: 2-s2.0-0030692076 12/31/1997 98 Citations

Effect of intermittent weight bearing on soleus fiber force-velocity-power and force-pCa relationships. (Bangart JJ, Widrick JJ, Fitts RH) J Appl Physiol (1985) 1997 Jun;82(6):1905-10 PMID: 9173957 SCOPUS ID: 2-s2.0-0030915079 06/01/1997 29 Citations

Contractile properties of rat, rhesus monkey, and human type I muscle fibers. (Widrick JJ, Romatowski JG, Karhanek M, Fitts RH) Am J Physiol 1997 Jan;272(1 Pt 2):R34-42 PMID: 9038988 SCOPUS ID: 2-s2.0-0031023305 01/01/1997 42 Citations

Peak force and maximal shortening velocity of soleus fibers after non-weight-bearing and resistance exercise. (Widrick JJ, Fitts RH) J Appl Physiol (1985) 1997 Jan;82(1):189-95 PMID: 9029215 SCOPUS ID: 2-s2.0-0031034102 01/01/1997 24 Citations

Effects of fatiguing stimulation on intracellular Na+ and K+ in frog skeletal muscle. (Balog EM, Fitts RH) J Appl Physiol (1985) 1996 Aug;81(2):679-85 PMID: 8872634 SCOPUS ID: 2-s2.0-0029785783 08/01/1996 56 Citations

Force-velocity and force-power properties of single muscle fibers from elite master runners and sedentary men. (Widrick JJ, Trappe SW, Costill DL, Fitts RH) Am J Physiol 1996 Aug;271(2 Pt 1):C676-83 PMID: 8770009 SCOPUS ID: 2-s2.0-0029736697 08/01/1996 105 Citations

Isometric force and maximal shortening velocity of single muscle fibers from elite master runners. (Widrick JJ, Trappe SW, Blaser CA, Costill DL, Fitts RH) Am J Physiol 1996 Aug;271(2 Pt 1):C666-75 PMID: 8770008 SCOPUS ID: 2-s2.0-0029736744 08/01/1996 103 Citations

Soleus fiber force and maximal shortening velocity after non-weight bearing with intermittent activity. (Widrick JJ, Bangart JJ, Karhanek M, Fitts RH) J Appl Physiol (1985) 1996 Mar;80(3):981-7 PMID: 8964764 SCOPUS ID: 2-s2.0-0029868942 03/01/1996 33 Citations

Effect of intracellular and extracellular ion changes on E-C coupling and skeletal muscle fatigue. (Fitts RH, Balog EM) Acta Physiol Scand 1996 Mar;156(3):169-81 PMID: 8729677 SCOPUS ID: 2-s2.0-0029987805 03/01/1996 47 Citations

Muscle fatigue: the cellular aspects. (Fitts RH) Am J Sports Med 1996;24(6 Suppl):S9-13 PMID: 8947417 SCOPUS ID: 2-s2.0-0030460709 01/01/1996 68 Citations

Muscle mechanics: adaptations with exercise-training. (Fitts RH, Widrick JJ) Exerc Sport Sci Rev 1996;24:427-73 PMID: 8744258 SCOPUS ID: 2-s2.0-0029689570 01/01/1996 167 Citations

Effect of hindlimb unloading on rat soleus fiber force, stiffness, and calcium sensitivity. (McDonald KS, Fitts RH) J Appl Physiol (1985) 1995 Nov;79(5):1796-802 PMID: 8594043 SCOPUS ID: 2-s2.0-0028883798 11/01/1995 92 Citations

The dihydropyridine nitrendipine inhibits [3H]MK 801 binding to mouse brain sections. (Filloux FM, Fitts RC, Skeen GA, White HS) Eur J Pharmacol 1994 Nov 15;269(3):325-30 PMID: 7534709 SCOPUS ID: 2-s2.0-0028172966 11/15/1994 15 Citations

Force-velocity and power characteristics of rat soleus muscle fibers after hindlimb suspension. (McDonald KS, Blaser CA, Fitts RH) J Appl Physiol (1985) 1994 Oct;77(4):1609-16 PMID: 7836176 SCOPUS ID: 2-s2.0-0027997832 10/01/1994 59 Citations

Shortening velocity and ATPase activity of rat skeletal muscle fibers: effects of endurance exercise training. (Schluter JM, Fitts RH) Am J Physiol 1994 Jun;266(6 Pt 1):C1699-1713 PMID: 8023900 SCOPUS ID: 2-s2.0-0028356848 06/01/1994 79 Citations

Role of sarcolemma action potentials and excitability in muscle fatigue. (Balog EM, Thompson LV, Fitts RH) J Appl Physiol (1985) 1994 May;76(5):2157-62 PMID: 8063681 SCOPUS ID: 2-s2.0-0028305080 05/01/1994 61 Citations

Cellular mechanisms of muscle fatigue. (Fitts RH) Physiol Rev 1994 Jan;74(1):49-94 PMID: 8295935 SCOPUS ID: 2-s2.0-0028107645 01/01/1994 1179 Citations

Effect of hindlimb unweighting on single soleus fiber maximal shortening velocity and ATPase activity. (McDonald KS, Fitts RH) J Appl Physiol (1985) 1993 Jun;74(6):2949-57 PMID: 8365995 SCOPUS ID: 2-s2.0-0027213241 06/01/1993 48 Citations

Muscle fatigue in the frog semitendinosus: role of the high-energy phosphates and Pi. (Thompson LV, Fitts RH) Am J Physiol 1992 Oct;263(4 Pt 1):C803-9 PMID: 1415669 SCOPUS ID: 2-s2.0-0026808380 10/01/1992 29 Citations

Fatigability and blood flow in the rat gastrocnemius-plantaris-soleus after hindlimb suspension. (McDonald KS, Delp MD, Fitts RH) J Appl Physiol (1985) 1992 Sep;73(3):1135-40 PMID: 1400027 SCOPUS ID: 2-s2.0-0026700241 09/01/1992 48 Citations

Muscle fatigue in frog semitendinosus: alterations in contractile function. (Thompson LV, Balog EM, Riley DA, Fitts RH) Am J Physiol 1992 Jun;262(6 Pt 1):C1500-6 PMID: 1535482 SCOPUS ID: 2-s2.0-0026647439 06/01/1992 37 Citations

Effect of hindlimb unweighting on tissue blood flow in the rat. (McDonald KS, Delp MD, Fitts RH) J Appl Physiol (1985) 1992 Jun;72(6):2210-8 PMID: 1629075 SCOPUS ID: 2-s2.0-0026729056 06/01/1992 123 Citations

Muscle fatigue in frog semitendinosus: role of intracellular pH. (Thompson LV, Balog EM, Fitts RH) Am J Physiol 1992 Jun;262(6 Pt 1):C1507-12 PMID: 1616012 SCOPUS ID: 2-s2.0-0026703741 06/01/1992 20 Citations

The determinants of skeletal muscle force and power: their adaptability with changes in activity pattern. (Fitts RH, McDonald KS, Schluter JM) J Biomech 1991;24 Suppl 1:111-22 PMID: 1791172 SCOPUS ID: 2-s2.0-0026347458 01/01/1991 141 Citations

The voltage sensor of excitation-contraction coupling in skeletal muscle. Ion dependence and selectivity. (Pizarro G, Fitts R, Uribe I, Ríos E) J Gen Physiol 1989 Sep;94(3):405-28 PMID: 2481710 PMCID: PMC2228956 SCOPUS ID: 2-s2.0-0024359120 09/01/1989 46 Citations

Contractile function of single muscle fibers after hindlimb suspension. (Gardetto PR, Schluter JM, Fitts RH) J Appl Physiol (1985) 1989 Jun;66(6):2739-49 PMID: 2745338 SCOPUS ID: 2-s2.0-0024392879 06/01/1989 135 Citations

Single muscle fiber enzyme shifts with hindlimb suspension and immobilization. (Fitts RH, Brimmer CJ, Heywood-Cooksey A, Timmerman RJ) Am J Physiol 1989 May;256(5 Pt 1):C1082-91 PMID: 2719097 SCOPUS ID: 2-s2.0-0024563658 05/01/1989 37 Citations

Effect of swim exercise training on human muscle fiber function. (Fitts RH, Costill DL, Gardetto PR) J Appl Physiol (1985) 1989 Jan;66(1):465-75 PMID: 2917951 SCOPUS ID: 2-s2.0-0024595537 01/01/1989 119 Citations

Voltage sensors of the frog skeletal muscle membrane require calcium to function in excitation-contraction coupling. (Brum G, Fitts R, Pizarro G, Ríos E) J Physiol 1988 Apr;398:475-505 PMID: 3260626 PMCID: PMC1191783 SCOPUS ID: 2-s2.0-0023911351 04/01/1988 102 Citations

Bacterial catalysis of nitrosation: involvement of the nar operon of Escherichia coli. (Ralt D, Wishnok JS, Fitts R, Tannenbaum SR) J Bacteriol 1988 Jan;170(1):359-64 PMID: 3275620 PMCID: PMC210650 SCOPUS ID: 2-s2.0-0023742156 01/01/1988 60 Citations

Fatigue from high- and low-frequency muscle stimulation: contractile and biochemical alterations. (Metzger JM, Fitts RH) J Appl Physiol (1985) 1987 May;62(5):2075-82 PMID: 3597276 SCOPUS ID: 2-s2.0-0023192907 05/01/1987 51 Citations

Role of intracellular pH in muscle fatigue. (Metzger JM, Fitts RH) J Appl Physiol (1985) 1987 Apr;62(4):1392-7 PMID: 3597214 SCOPUS ID: 2-s2.0-0023276899 04/01/1987 81 Citations

Fatigue from high- and low-frequency muscle stimulation: role of sarcolemma action potentials. (Metzger JM, Fitts RH) Exp Neurol 1986 Aug;93(2):320-33 PMID: 3732473 SCOPUS ID: 2-s2.0-0022539545 08/01/1986 68 Citations

Models of disuse: a comparison of hindlimb suspension and immobilization. (Fitts RH, Metzger JM, Riley DA, Unsworth BR) J Appl Physiol (1985) 1986 Jun;60(6):1946-53 PMID: 3722061 SCOPUS ID: 2-s2.0-0022476925 06/01/1986 164 Citations

Contractile and biochemical properties of diaphragm: effects of exercise training and fatigue. (Metzger JM, Fitts RH) J Appl Physiol (1985) 1986 May;60(5):1752-8 PMID: 2940218 SCOPUS ID: 2-s2.0-0022483725 05/01/1986 42 Citations

Effect of high-intensity exercise training on functional capacity of limb skeletal muscle. (Troup JP, Metzger JM, Fitts RH) J Appl Physiol (1985) 1986 May;60(5):1743-51 PMID: 2940217 SCOPUS ID: 2-s2.0-0022500366 05/01/1986 36 Citations

Recovery in skeletal muscle contractile function after prolonged hindlimb immobilization. (Fitts RH, Brimmer CJ) J Appl Physiol (1985) 1985 Sep;59(3):916-23 PMID: 4055577 SCOPUS ID: 2-s2.0-0022407162 09/01/1985 28 Citations

Histochemical and physiological characteristics of the rat diaphragm. (Metzger JM, Scheidt KB, Fitts RH) J Appl Physiol (1985) 1985 Apr;58(4):1085-91 PMID: 3988665 SCOPUS ID: 2-s2.0-0021811837 04/01/1985 83 Citations

The effect of ageing and exercise on skeletal muscle function. (Fitts RH, Troup JP, Witzmann FA, Holloszy JO) Mech Ageing Dev 1984 Oct 15;27(2):161-72 PMID: 6492893 SCOPUS ID: 2-s2.0-0021592409 10/15/1984 93 Citations

Contractile and fatigue properties of thyrotoxic rat skeletal muscle. (Fitts RH, Brimmer CJ, Troup JP, Unsworth BR) Muscle Nerve 1984;7(6):470-7 PMID: 6543899 SCOPUS ID: 2-s2.0-0021269917 07/01/1984 27 Citations

Effect of hindlimb immobilization on the fatigability of skeletal muscle. (Witzmann FA, Kim DH, Fitts RH) J Appl Physiol Respir Environ Exerc Physiol 1983 May;54(5):1242-8 PMID: 6863083 SCOPUS ID: 2-s2.0-0020570217 05/01/1983 47 Citations

A comparison of rat myosin from fast and slow skeletal muscle and the effect of disuse. (Unsworth BR, Witzmann FA, Fitts RH) J Biol Chem 1982 Dec 25;257(24):15129-36 PMID: 6217202 SCOPUS ID: 2-s2.0-0020443495 12/25/1982 19 Citations

Acid phosphatase and protease activities in immobilized rat skeletal muscles. (Witzmann FA, Troup JP, Fitts RH) Can J Physiol Pharmacol 1982 Dec;60(12):1732-6 PMID: 6762246 SCOPUS ID: 2-s2.0-0020356237 12/01/1982 12 Citations

Effect of thyrotoxicosis on sarcoplasmic reticulum in rat skeletal muscle. (Kim DH, Witzmann FA, Fitts RH) Am J Physiol 1982 Sep;243(3):C151-5 PMID: 7114246 SCOPUS ID: 2-s2.0-0019982551 09/01/1982 32 Citations

Effect of disuse on sarcoplasmic reticulum in fast and slow skeletal muscle. (Kim DH, Witzmann FA, Fitts RH) Am J Physiol 1982 Sep;243(3):C156-60 PMID: 6214192 SCOPUS ID: 2-s2.0-0019994641 09/01/1982 33 Citations

Hindlimb immobilization: length-tension and contractile properties of skeletal muscle. (Witzmann FA, Kim DH, Fitts RH) J Appl Physiol Respir Environ Exerc Physiol 1982 Aug;53(2):335-45 PMID: 7118655 SCOPUS ID: 2-s2.0-0019982826 08/01/1982 135 Citations

Recovery time course in contractile function of fast and slow skeletal muscle after hindlimb immobilization. (Witzmann FA, Kim DH, Fitts RH) J Appl Physiol Respir Environ Exerc Physiol 1982 Mar;52(3):677-82 PMID: 7068483 SCOPUS ID: 2-s2.0-0019968594 03/01/1982 63 Citations

Muscle fatigue with prolonged exercise: contractile and biochemical alterations. (Fitts RH, Courtright JB, Kim DH, Witzmann FA) Am J Physiol 1982 Jan;242(1):C65-73 PMID: 6120654 SCOPUS ID: 2-s2.0-0020006440 01/01/1982 89 Citations

The effect of exercise-training on sarcoplasmic reticulum function in fast and slow skeletal muscle. (Kim DH, Wible GS, Witzmann FA, Fitts RH) Life Sci 1981 Jun 08;28(23):2671-7 PMID: 7266245 SCOPUS ID: 2-s2.0-0019860233 06/08/1981 18 Citations

A comparison of sarcoplasmic reticulum function in fast and slow skeletal muscle using crude homogenate and isolated vesicles. (Kim DH, Witzmann FA, Fitts RH) Life Sci 1981 May 18;28(20):2223-9 PMID: 7253818 SCOPUS ID: 2-s2.0-0019831726 05/18/1981 23 Citations

Effect of moderate daily exercise on acute glomerulonephritis. (Stefaniak JE, Hebert LA, Garancis JC, Sadowski ME, Shapiro DS, Fitts RH, Courtright JB, Cornacoff JB) Nephron 1981;29(1-2):49-54 PMID: 7329474 SCOPUS ID: 2-s2.0-0019781534 01/01/1981 7 Citations

Integration of bacteriophage Mu at host chromosomal replication forks during lytic development. (Fitts RA, Taylor AL) Proc Natl Acad Sci U S A 1980 May;77(5):2801-5 PMID: 6446718 PMCID: PMC349492 SCOPUS ID: 2-s2.0-0018819002 05/01/1980 7 Citations

Contractile, biochemical, and histochemical properties of thyrotoxic rat soleus muscle. (Fitts RH, Winder WW, Brooke MH, Kaiser KK, Holloszy JO) Am J Physiol 1980 Jan;238(1):C14-20 PMID: 6444499 SCOPUS ID: 2-s2.0-0018814373 01/01/1980 53 Citations

Effects of thyrotoxicosis on mitochondrial enzymes of rat soleus. (Courtright JB, Fitts RH) Horm Metab Res 1979 Apr;11(4):304-6 PMID: 222661 SCOPUS ID: 2-s2.0-0018759175 04/01/1979 8 Citations

Effects of fatigue and recovery on contractile properties of frog muscle. (Fitts RH, Holloszy JO) J Appl Physiol Respir Environ Exerc Physiol 1978 Dec;45(6):899-902 PMID: 310431 SCOPUS ID: 2-s2.0-0018255549 12/01/1978 26 Citations

Contractile properties of rat soleus muscle: effects of training and fatique. (Fitts RH, Holloszy JO) Am J Physiol 1977 Sep;233(3):C86-91 PMID: 143894 SCOPUS ID: 2-s2.0-0017657897 09/01/1977 68 Citations

The effects of exercise-training on the development of fatigue. (Fitts RH) Ann N Y Acad Sci 1977;301:424-30 PMID: 270931 SCOPUS ID: 2-s2.0-0017625178 01/01/1977 5 Citations

Effects of fatty acids and contraction on rat soleus muscle metabolites [proceedings]. (Fitts RH, Holloszy JO, Rennie MJ) J Physiol 1976 Dec;263(1):160P-161P PMID: 1011120 SCOPUS ID: 2-s2.0-0017248236 12/01/1976 4 Citations

Lactate and contractile force in frog muscle during development of fatigue and recovery. (Fitts RH, Holloszy JO) Am J Physiol 1976 Aug;231(2):430-3 PMID: 1085570 SCOPUS ID: 2-s2.0-0017201393 08/01/1976 95 Citations

Phosphorylated beta-guanidinopropionate as a substitute for phosphocreatine in rat muscle. (Fitch CD, Jellinek M, Fitts RH, Baldwin KM, Holloszy JO) Am J Physiol 1975 Apr;228(4):1123-5 PMID: 1130513 SCOPUS ID: 2-s2.0-0016684377 04/01/1975 56 Citations

Effect of exercise on response of liver lipogenic enzymes to a high fructose diet. (Winder WW, Booth FW, Fitts RH, Holloszy JO) Proc Soc Exp Biol Med 1975 Apr;148(4):1150-4 PMID: 236576 SCOPUS ID: 2-s2.0-0016710115 04/01/1975 10 Citations

Skeletal muscle respiratory capacity, endurance, and glycogen utilization. (Fitts RH, Booth FW, Winder WW, Holloszy JO) Am J Physiol 1975 Apr;228(4):1029-33 PMID: 165725 SCOPUS ID: 2-s2.0-0016795518 04/01/1975 167 Citations

Depletion of muscle and liver glycogen during exercise. Protective effect of training. (Baldwin KM, Fitts RH, Booth FW, Winder WW, Holloszy JO) Pflugers Arch 1975;354(3):203-12 PMID: 1167678 SCOPUS ID: 2-s2.0-0016429957 01/01/1975 89 Citations

The adaptation of myoglobin with age and training and its relationship to the three fiber types of skeletal muscle in miniature pig. (Fitts RH, Nagle FJ, Cassens RG) Eur J Appl Physiol Occup Physiol 1974;33(4):275-84 PMID: 4442407 SCOPUS ID: 2-s2.0-0016318348 01/01/1974 2 Citations

Characteristics of skeletal muscle fiber types in the miniature pig and the effect of training. (Fitts RH, Nagle FJ, Cassens RG) Can J Physiol Pharmacol 1973 Nov;51(11):825-31 PMID: 4762429 SCOPUS ID: 2-s2.0-0015815512 11/01/1973 14 Citations

Contractile properties of skeletal muscle from trained miniature pig. (Fitts R, Campion D, Nagle F, Cassens R) Pflugers Arch 1973 Oct 17;343(2):133-41 PMID: 4797849 SCOPUS ID: 2-s2.0-0015797671 10/17/1973 10 Citations

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Robert Fitts PhD

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Publications (119)