Faculty Collaboration Database

Effect of high-intensity exercise training on functional capacity of limb skeletal muscle. J Appl Physiol (1985) 1986 May;60(5):1743-51

Date

05/01/1986

Pubmed ID

2940217

DOI

10.1152/jappl.1986.60.5.1743

Scopus ID

2-s2.0-0022500366 (requires institutional sign-in at Scopus site)   36 Citations

Abstract

The purpose of this study was to determine whether a program of regular sprint exercise training alters the functional properties or protects against the development of fatigue in fast- and slow-twitch rat skeletal muscle. The training program consisted of 6 sprints of 4.5-min duration at 40 m/min and 15% slope with 2.5-min rest intervals, performed 5 days/wk for 6 wk. The exercise program significantly increased (P less than 0.05) citrate synthase activity (mumol X g-1 X min-1) in the predominantly type I soleus (SOL) from 28 +/- 2 to 44 +/- 2; the type IIb superficial region of the vastus lateralis (SVL) from 10 +/- 1 to 16 +/- 1; and the type IIa deep region of the vastus lateralis (DVL) from 34 +/- 2 to 53 +/- 2. Phosphofructokinase activity (mumol X g-1 X min-1) also increased with training in the SOL (17 +/- 1 vs. 23 +/- 1) and the DVL (64 +/- 5 vs. 79 +/- 5). Sprint training reduced (P less than 0.05) the contraction time (CT) (111 +/- 7 vs. 92 +/- 3 ms) and the one-half relaxation time (118 +/- 3 vs. 104 +/- 2 ms) in the slow-twitch soleus. The exercise program also induced a decreased CT in the fast-twitch extensor digitorum longus (EDL), but significance was limited to the P less than 0.1 level. Muscle fatigue was produced by electrical stimulation at 45 trains/min and either 15 trains/min in SOL or 10 trains/min in the EDL and SVL for 1, 5, or 10 min.(ABSTRACT TRUNCATED AT 250 WORDS)

Author List

Troup JP, Metzger JM, Fitts RH

Author

Robert Fitts PhD Professor in the Biological Sciences department at Marquette University

MESH terms used to index this publication - Major topics in bold

Adenosine Triphosphate
Animals
Citrate (si)-Synthase
Extremities
Female
Hydrogen-Ion Concentration
In Vitro Techniques
Lactates
Lactic Acid
Muscle Contraction
Muscles
Phosphocreatine
Phosphofructokinase-1
Physical Conditioning, Animal
Physical Exertion
Rats
Rats, Inbred Strains