Faculty Collaboration Database

Effect of moderate daily exercise on acute glomerulonephritis. Nephron 1981;29(1-2):49-54

Date

01/01/1981

Pubmed ID

7329474

DOI

10.1159/000182238

Scopus ID

2-s2.0-0019781534 (requires institutional sign-in at Scopus site)   7 Citations

Abstract

Exercise can induce proteinuria, hematuria and cylindruria in normal individuals. This suggests that exercise adversely affects glomerular function. In this study we examined the impact of moderate daily treadmill exercise on the glomerulonephritis (GN) of 'one-shot' bovine serum albumin (250 mg/kg i.v.) serum sickness in rabbits. We found that exercise alone increased serum creatinine concentration (Scr) but exercise plus GN did not increase Scr further. Blood urea nitrogen values were unchanged. Albuminuria and the renal histopathology findings were not different between the exercised and non-exercised groups of rabbits. Muscle cytochrome oxidase and mitochondrial protein concentrations were not increased in the exercised animals. We conclude that exercise, below the level that causes exercise adaptation in muscle enzymes, does not adversely affect this form of acute GN.

Author List

Stefaniak JE, Hebert LA, Garancis JC, Sadowski ME, Shapiro DS, Fitts RH, Courtright JB, Cornacoff JB

Author

Robert Fitts PhD Professor in the Biological Sciences department at Marquette University

MESH terms used to index this publication - Major topics in bold

Acute Disease
Albuminuria
Animals
Blood Urea Nitrogen
Creatinine
Female
Glomerulonephritis
Kidney
Male
Physical Exertion
Rabbits
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