Faculty Collaboration Database

Kidney Injury in Liver Disease. Crit Care Clin 2016 Jul;32(3):343-55

Date

06/25/2016

Pubmed ID

27339675

DOI

10.1016/j.ccc.2016.03.005

Scopus ID

2-s2.0-84974805097 (requires institutional sign-in at Scopus site)   23 Citations

Abstract

Acute kidney injury (AKI) occurs frequently in patients with liver disease and increases morbidity and mortality. Hepatorenal syndrome is a common cause of AKI in patients with decompensated cirrhosis and is due to alterations in systemic and renal hemodynamics. Serum creatinine-based estimation of kidney function is a key component of the Model for End-stage Liver Disease score in liver transplant candidates. Continuous renal replacement therapy is used in critically ill patients with liver failure and AKI. Simultaneous liver-kidney transplantation (SLK) may be required in patients with liver failure and prolonged AKI. Identification of appropriate candidates for SLK remains controversial.

Author List

Regner KR, Singbartl K

Author

Kevin R. Regner MD Interim Chair, Professor in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Acidosis
Acute Kidney Injury
Chronic Disease
Hepatorenal Syndrome
Humans
Kidney Transplantation
Liver Diseases
Liver Failure, Acute
Liver Transplantation
Renal Replacement Therapy