Kevin R. Regner MD
Research Experience
HemofiltrationKidney Failure, ChronicKidney Tubular Necrosis, AcuteKidney Tubules, ProximalRenal Replacement TherapyPublications (57)
Nephrologist-Led Simulation-Based Focused Cardiac Ultrasound Workshop for Medical Students: Insights and Implications (Koratala A, Paudel HR, Regner KR) American Journal of Medicine Open 2023 Dec;10: 2667-0364 10/01/2023 Incidence and outcomes of acute kidney injury including hepatorenal syndrome in hospitalized patients with cirrhosis in the US. (Patidar KR, Belcher JM, Regner KR, St Hillien SA, Simonetto DA, Asrani SK, Neyra JA, Sharma P, Velez JCQ, Wadei H, Nadim MK, Chung RT, Seethapathy R, Parada XV, Ouyang T, Ufere NN, Robinson JE, McLean Diaz P, Wilechansky RM, Przybyszewski EM, Smith TN, Ali AA, Orman ES, Schulz P, Siddiqui SM, Shabbir R, Liu LJ, Cama-Olivares A, Flannery AH, Baker ML, Gunasekaran D, Aswine A, Issa R, Li J, Verma S, Chalmers D, Varghese V, Lam W, Mohamed M, Kovacic R, Gaddy A, Attieh RM, Cortes P, Semnani S, Wang L, Khemichian S, Allegretti AS, from the HRS-HARMONY consortium) J Hepatol 2023 Dec;79(6):1408-1417 PMID: 37517455 PMCID: PMC10807505 SCOPUS ID: 2-s2.0-85171850314 07/31/2023 9 CitationsUpdate on Assessment of Estimated Glomerular Filtration Rate in Patients With Cirrhosis. (Griffin C, Asrani SK, Regner KR) Adv Kidney Dis Health 2023 Jul;30(4):307-314 PMID: 37389536 SCOPUS ID: 2-s2.0-85186295119 06/30/2023 Identification of cell division cycle protein 20 in various forms of acute and chronic kidney injury in mice. (Swanson M, Yun J, Collier DM, Seif C, Yang CY, Regner KR, Park F) Am J Physiol Renal Physiol 2023 Aug 01;325(2):F248-F261 PMID: 37348027 SCOPUS ID: 2-s2.0-85165546515 06/22/2023 Responsiveness to Vasoconstrictor Therapy in Hepatorenal Syndrome Type 1. (Velez JCQ, Karakala N, Tayebi K, Wickman TJ, Mohamed MMB, Kovacic RA, Therapondos G, Kanduri SR, Allegretti AS, Belcher JM, Regner KR, Wentowski C) Kidney360 2023 Apr 01;4(4):e448-e456 PMID: 36763632 PMCID: PMC10278824 SCOPUS ID: 2-s2.0-85161650241 02/11/2023 3 Citationsp66Shc signaling does not contribute to tubular damage induced by renal ischemia-reperfusion injury in rat (Miller B, Regner K, Sorokin A) Biochemical and Biophysical Research Communications 7 May 2022;603:69-74 SCOPUS ID: 2-s2.0-85125835040 05/07/2022 p66Shc signaling does not contribute to tubular damage induced by renal ischemia-reperfusion injury in rat. (Miller B, Regner K, Sorokin A) Biochem Biophys Res Commun 2022 May 07;603:69-74 PMID: 35278882 PMCID: PMC8969123 SCOPUS ID: 2-s2.0-85125835040 03/13/2022 Cannabinoid Type 2 Receptor Activation Reduces the Progression of Kidney Fibrosis Using a Mouse Model of Unilateral Ureteral Obstruction. (Swanson ML, Regner KR, Moore BM 2nd, Park F) Cannabis Cannabinoid Res 2022 Dec;7(6):790-803 PMID: 35196117 SCOPUS ID: 2-s2.0-85147378966 02/24/2022 5 CitationsHyperammonemia from a urea cycle disorder presenting in adulthood (Priester TC, Khoo T, Fernández-Pérez ER, Regner KR, Tracy JA, Mitchell S, Summar ML, Babovic-Vuksanovic D) The Open Crit Care Med J. 2009 02/23/2022 Management of AKI in patients with cirrhosis (Regner KR, Kanduri SR, Velez JCQ) Curr Treat Options Gastro 2022; 20:295-315. 02/23/2022 Histologically resolved small RNA maps in primary focal segmental glomerulosclerosis indicate progressive changes within glomerular and tubulointerstitial regions. (Williams AM, Jensen DM, Pan X, Liu P, Liu J, Huls S, Regner KR, Iczkowski KA, Wang F, Li J, Gallan AJ, Wang T, Baker MA, Liu Y, Lalehzari N, Liang M) Kidney Int 2022 Apr;101(4):766-778 PMID: 35114200 PMCID: PMC8940673 SCOPUS ID: 2-s2.0-85125312317 02/04/2022 12 CitationsDNA damage is overcome by TRIP13 overexpression during cisplatin nephrotoxicity. (Hama T, Nagesh PK, Chowdhury P, Moore BM 2nd, Yallapu MM, Regner KR, Park F) JCI Insight 2021 Nov 22;6(22) PMID: 34806647 PMCID: PMC8663775 SCOPUS ID: 2-s2.0-85120382452 11/23/2021 4 CitationsDNA damage is overcome by TRIP13 overexpression during cisplatin nephrotoxicity (Hama T, Nagesh PKB, Chowdhury P, Moore BM, Yallapu MM, Regner KR, Park F) JCI Insight 22 November 2021;6(22) SCOPUS ID: 2-s2.0-85120382452 11/22/2021 4 CitationsTerlipressin and the Treatment of Hepatorenal Syndrome: How the CONFIRM Trial Moves the Story Forward. (Belcher JM, Parada XV, Simonetto DA, Juncos LA, Karakala N, Wadei HM, Sharma P, Regner KR, Nadim MK, Garcia-Tsao G, Velez JCQ, Parikh SM, Chung RT, Allegretti AS, HRS-HARMONY Study Investigators) Am J Kidney Dis 2022 May;79(5):737-745 PMID: 34606933 SCOPUS ID: 2-s2.0-85122545748 10/05/2021 22 CitationsUrinary NGAL as a Diagnostic and Prognostic Marker for Acute Kidney Injury in Cirrhosis: A Prospective Study. (Allegretti AS, Parada XV, Endres P, Zhao S, Krinsky S, St Hillien SA, Kalim S, Nigwekar SU, Flood JG, Nixon A, Simonetto DA, Juncos LA, Karakala N, Wadei HM, Regner KR, Belcher JM, Nadim MK, Garcia-Tsao G, Velez JCQ, Parikh SM, Chung RT, HRS-HARMONY study investigators) Clin Transl Gastroenterol 2021 May 11;12(5):e00359 PMID: 33979307 PMCID: PMC8116001 SCOPUS ID: 2-s2.0-85105838703 05/13/2021 58 CitationsAKI in Hospitalized Patients with COVID-19 and Seasonal Influenza: A Comparative Analysis. (Bhasin B, Veitla V, Dawson AZ, Garacci Z, Sturgill D, Ozieh MN, Regner KR) Kidney360 2021 Apr 29;2(4):619-628 PMID: 35373047 PMCID: PMC8791326 SCOPUS ID: 2-s2.0-85107688077 02/26/2021 6 CitationsPatients with Hepatorenal Syndrome Should Be Dialyzed? COMMENTARY. (Regner KR) Kidney360 2021 Mar 25;2(3):413-414 PMID: 35378024 PMCID: PMC8786001 SCOPUS ID: 2-s2.0-85127132316 12/16/2020 1 CitationEndogenous miR-204 Protects the Kidney against Chronic Injury in Hypertension and Diabetes. (Cheng Y, Wang D, Wang F, Liu J, Huang B, Baker MA, Yin J, Wu R, Liu X, Regner KR, Usa K, Liu Y, Zhang C, Dong L, Geurts AM, Wang N, Miller SS, He Y, Liang M) J Am Soc Nephrol 2020 Jul;31(7):1539-1554 PMID: 32487559 PMCID: PMC7350998 SCOPUS ID: 2-s2.0-85087468924 06/04/2020 52 CitationsMicroRNA-214-3p in the Kidney Contributes to the Development of Hypertension. (Liu Y, Usa K, Wang F, Liu P, Geurts AM, Li J, Williams AM, Regner KR, Kong Y, Liu H, Nie J, Liang M) J Am Soc Nephrol 2018 Oct;29(10):2518-2528 PMID: 30049682 PMCID: PMC6171279 SCOPUS ID: 2-s2.0-85053979457 07/28/2018 44 CitationsUrinary exosomal expression of activator of G protein signaling 3 in polycystic kidney disease. (Keri KC, Regner KR, Dall AT, Park F) BMC Res Notes 2018 Jun 07;11(1):359 PMID: 29880041 PMCID: PMC5992714 SCOPUS ID: 2-s2.0-85048187272 06/09/2018 19 CitationsArtificial intelligence, physiological genomics, and precision medicine. (Williams AM, Liu Y, Regner KR, Jotterand F, Liu P, Liang M) Physiol Genomics 2018 Apr 01;50(4):237-243 PMID: 29373082 PMCID: PMC5966805 SCOPUS ID: 2-s2.0-85046104804 01/27/2018 78 CitationsTissue-Specific MicroRNA Expression Patterns in Four Types of Kidney Disease. (Baker MA, Davis SJ, Liu P, Pan X, Williams AM, Iczkowski KA, Gallagher ST, Bishop K, Regner KR, Liu Y, Liang M) J Am Soc Nephrol 2017 Oct;28(10):2985-2992 PMID: 28663230 PMCID: PMC5619963 SCOPUS ID: 2-s2.0-85030470491 07/01/2017 93 CitationsTRIP13-deficient tubular epithelial cells are susceptible to apoptosis following acute kidney injury. (Pressly JD, Hama T, Brien SO, Regner KR, Park F) Sci Rep 2017 Mar 03;7:43196 PMID: 28256593 PMCID: PMC5335694 SCOPUS ID: 2-s2.0-85014629995 03/04/2017 14 CitationsOutcome analysis of continuous intraoperative renal replacement therapy in the highest acuity liver transplant recipients: A single-center experience. (Zimmerman MA, Selim M, Kim J, Regner K, Saeian K, Zanowski S, Martin A, Connolly LA, Lauer KK, Woehlck HJ, Hong JC) Surgery 2017 May;161(5):1279-1286 PMID: 28011008 SCOPUS ID: 2-s2.0-85008237865 12/25/2016 22 CitationsKidney Injury in Liver Disease. (Regner KR, Singbartl K) Crit Care Clin 2016 Jul;32(3):343-55 PMID: 27339675 SCOPUS ID: 2-s2.0-84974805097 06/25/2016 22 CitationsDeficiency in the Formation of 20-Hydroxyeicosatetraenoic Acid Enhances Renal Ischemia-Reperfusion Injury. (Muroya Y, Fan F, Regner KR, Falck JR, Garrett MR, Juncos LA, Roman RJ) J Am Soc Nephrol 2015 Oct;26(10):2460-9 PMID: 25644108 PMCID: PMC4587700 SCOPUS ID: 2-s2.0-84942938562 02/04/2015 23 CitationsActivator of G-protein Signaling 3 Controls Renal Epithelial Cell Survival and ERK5 Activation. (Rasmussen SA, Kwon M, Pressly JD, Blumer JB, Regner KR, Park F) J Mol Signal 2015 Nov 27;10:6 PMID: 27096004 PMCID: PMC4831271 SCOPUS ID: 2-s2.0-84988694039 01/01/2015 4 CitationsLocalization and expression profile of Group I and II Activators of G-protein Signaling in the kidney. (Lenarczyk M, Pressly JD, Arnett J, Regner KR, Park F) J Mol Histol 2015 Apr;46(2):123-36 PMID: 25533045 PMCID: PMC4369180 SCOPUS ID: 2-s2.0-84925517942 12/24/2014 12 CitationsG-protein βγ subunit dimers modulate kidney repair after ischemia-reperfusion injury in rats. (White SM, North LM, Haines E, Goldberg M, Sullivan LM, Pressly JD, Weber DS, Park F, Regner KR) Mol Pharmacol 2014 Oct;86(4):369-77 PMID: 25028481 PMCID: PMC4164983 SCOPUS ID: 2-s2.0-84907912300 07/17/2014 14 CitationsDe novo expression of sodium-glucose cotransporter SGLT2 in Bowman's capsule coincides with replacement of parietal epithelial cell layer with proximal tubule-like epithelium. (Tabatabai NM, North PE, Regner KR, Kumar SN, Duris CB, Blodgett AB) J Membr Biol 2014 Aug;247(8):675-83 PMID: 24906870 PMCID: PMC4117812 SCOPUS ID: 2-s2.0-84905576038 06/08/2014 6 CitationsGenetic susceptibility and loss of Nr4a1 enhances macrophage-mediated renal injury in CKD. (Westbrook L, Johnson AC, Regner KR, Williams JM, Mattson DL, Kyle PB, Henegar JR, Garrett MR) J Am Soc Nephrol 2014 Nov;25(11):2499-510 PMID: 24722447 PMCID: PMC4214519 SCOPUS ID: 2-s2.0-84920983217 04/12/2014 27 CitationsPhenytoin removal by continuous venovenous hemofiltration. (Oltrogge KM, Peppard WJ, Saleh M, Regner KR, Herrmann DJ) Ann Pharmacother 2013 Sep;47(9):1218-22 PMID: 24259740 SCOPUS ID: 2-s2.0-84884491746 11/22/2013 14 CitationsApproach to the patient with hematuria (Ratkalkar VN, Regner KR) Clinical Decisions in Nephrology, Hypertension and Kidney Transplantation 1 November 2013:43-49 SCOPUS ID: 2-s2.0-84929538735 11/01/2013 Genetic variants in Arhgef11 are associated with kidney injury in the Dahl salt-sensitive rat. (Williams JM, Johnson AC, Stelloh C, Dreisbach AW, Franceschini N, Regner KR, Townsend RR, Roman RJ, Garrett MR) Hypertension 2012 Nov;60(5):1157-68 PMID: 22987919 PMCID: PMC3505884 SCOPUS ID: 2-s2.0-84868200082 09/19/2012 28 CitationsGβγ Signaling Plays a Critical Role in Recovery from Renal Ischemia-Reperfusion Injury in Rats. (Haines EC, White SM, Park F, Regner KR) J Am Soc Nephrol 2012;23:113A 08/08/2012 Loss of Nuclear Receptor 4a1 on a Hypertensive Genetic Background Promotes Immune-Mediated Renal Injury (Westbrook L, Regner KR, Johnson AC, Lee J, Kyle PB, Mattson DL, Garrett MR) Hypertension. 2012; 60(3_MeetingAbstracts):A1 08/08/2012 Increased susceptibility to kidney injury by transfer of genomic segment from SHR onto Dahl S genetic background. (Regner KR, Harmon AC, Williams JM, Stelloh C, Johnson AC, Kyle PB, Lerch-Gaggl A, White SM, Garrett MR) Physiol Genomics 2012 Jun 15;44(12):629-37 PMID: 22548739 PMCID: PMC3426430 SCOPUS ID: 2-s2.0-84862628928 05/03/2012 13 CitationsUrinary interleukin-18 and urinary neutrophil gelatinase-associated lipocalin predict acute kidney injury following pulmonary valve replacement prior to serum creatinine. (Buelow MW, Dall A, Regner K, Weinberg C, Bartz PJ, Sowinski J, Rudd N, Katzmark L, Tweddell JS, Earing MG) Congenit Heart Dis 2012;7(5):441-7 PMID: 22537138 SCOPUS ID: 2-s2.0-84866460526 04/28/2012 25 CitationsEditorial Comment to Renoprotective effect of erythropoietin in ischemia/reperfusion injury: possible roles of the Akt/endothelial nitric oxide synthase-dependent pathway. (Regner KR) Int J Urol 2012 Mar;19(3):256 PMID: 22151694 SCOPUS ID: 2-s2.0-84857361563 12/14/2011 Dual role of microsomal prostaglandin E synthase 1 in chronic kidney disease. (Regner KR) Hypertension 2012 Jan;59(1):12-3 PMID: 22106400 SCOPUS ID: 2-s2.0-83655201134 11/23/2011 8 CitationsRole of medullary blood flow in the pathogenesis of renal ischemia-reperfusion injury. (Regner KR, Roman RJ) Curr Opin Nephrol Hypertens 2012 Jan;21(1):33-8 PMID: 22080855 PMCID: PMC3612396 SCOPUS ID: 2-s2.0-83055186460 11/15/2011 67 CitationsLoss of activator of G-protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents. (Regner KR, Nozu K, Lanier SM, Blumer JB, Avner ED, Sweeney WE Jr, Park F) FASEB J 2011 Jun;25(6):1844-55 PMID: 21343176 PMCID: PMC3101034 SCOPUS ID: 2-s2.0-79957927714 02/24/2011 37 Citations20-HETE in acute kidney injury. (Roman RJ, Akbulut T, Park F, Regner KR) Kidney Int 2011 Jan;79(1):10-3 PMID: 21157458 PMCID: PMC3146060 SCOPUS ID: 2-s2.0-78650266984 12/16/2010 19 CitationsProtective effect of Lifor solution in experimental renal ischemia-reperfusion injury. (Regner KR, Nilakantan V, Ryan RP, Mortensen J, White SM, Shames BD, Roman RJ) J Surg Res 2010 Dec;164(2):e291-7 PMID: 20888590 PMCID: PMC2991539 SCOPUS ID: 2-s2.0-78449301861 10/05/2010 30 CitationsCardiac myocyte-specific overexpression of human GTP cyclohydrolase I protects against acute cardiac allograft rejection. (Ionova IA, Vásquez-Vivar J, Cooley BC, Khanna AK, Whitsett J, Herrnreiter A, Migrino RQ, Ge ZD, Regner KR, Channon KM, Alp NJ, Pieper GM) Am J Physiol Heart Circ Physiol 2010 Jul;299(1):H88-96 PMID: 20418482 PMCID: PMC2904123 SCOPUS ID: 2-s2.0-77953745147 04/27/2010 8 CitationsHeterogeneous stock rats: a new model to study the genetics of renal phenotypes. (Solberg Woods LC, Stelloh C, Regner KR, Schwabe T, Eisenhauer J, Garrett MR) Am J Physiol Renal Physiol 2010 Jun;298(6):F1484-91 PMID: 20219828 PMCID: PMC2886820 SCOPUS ID: 2-s2.0-77952706580 03/12/2010 27 Citations20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism. (Akbulut T, Regner KR, Roman RJ, Avner ED, Falck JR, Park F) Am J Physiol Renal Physiol 2009 Sep;297(3):F662-70 PMID: 19570883 PMCID: PMC2739708 SCOPUS ID: 2-s2.0-69449101237 07/03/2009 46 CitationsMnTMPyP, a cell-permeant SOD mimetic, reduces oxidative stress and apoptosis following renal ischemia-reperfusion. (Liang HL, Hilton G, Mortensen J, Regner K, Johnson CP, Nilakantan V) Am J Physiol Renal Physiol 2009 Feb;296(2):F266-76 PMID: 19091787 PMCID: PMC2643863 SCOPUS ID: 2-s2.0-60549097415 12/19/2008 63 CitationsProtective effect of 20-HETE analogues in experimental renal ischemia reperfusion injury. (Regner KR, Zuk A, Van Why SK, Shames BD, Ryan RP, Falck JR, Manthati VL, McMullen ME, Ledbetter SR, Roman RJ) Kidney Int 2009 Mar;75(5):511-7 PMID: 19052533 PMCID: PMC2643317 SCOPUS ID: 2-s2.0-60749108287 12/05/2008 74 CitationsObstructive renal failure from malpositioned urinary catheter. (El-Zoghby ZM, Regner KR, Regner DM, Haugen EN) Kidney Int 2008 Jun;73(11):1330 PMID: 18480860 SCOPUS ID: 2-s2.0-43749122123 05/16/2008 1 CitationEpidemiology of acute kidney injury after cardiac surgery: An update (Regner KR) Journal of Organ Dysfunction 2007;3(4):232-239 SCOPUS ID: 2-s2.0-35848948866 11/14/2007 1 CitationAcute renal failure after cardiac surgery for carcinoid heart disease: incidence, risk factors, and prognosis. (Regner KR, Connolly HM, Schaff HV, Albright RC) Am J Kidney Dis 2005 May;45(5):826-32 PMID: 15861347 SCOPUS ID: 2-s2.0-26944442077 04/30/2005 30 Citations35-year-old woman with cough, fever, and anorexia. (Ensminger SA, Regner KR, Froehling DA) Mayo Clin Proc 2003 Jun;78(6):753-6 PMID: 12934787 SCOPUS ID: 2-s2.0-0038726875 08/26/2003 Serial measurement of serum tryptase in angiotensin-converting enzyme inhibitor-associated angioedema. (Regner KR, Riegert-Johnson DL, Volcheck GW) Mayo Clin Proc 2003 May;78(5):655-6 PMID: 12744557 SCOPUS ID: 2-s2.0-0038745593 05/15/2003 3 CitationsAngiotensin II blockade reduces radiation-induced proliferation in experimental radiation nephropathy. (Moulder JE, Fish BL, Regner KR, Cohen EP) Radiat Res 2002 Apr;157(4):393-401 PMID: 11893241 SCOPUS ID: 2-s2.0-0036210270 03/15/2002 24 CitationsRetinoic acid exacerbates experimental radiation nephropathy. (Moulder JE, Fish BL, Regner KR, Cohen EP, Raife TJ) Radiat Res 2002 Feb;157(2):199-203 PMID: 11835684 SCOPUS ID: 2-s2.0-0036152353 02/12/2002 20 CitationsStenotic glomerulotubular necks in radiation nephropathy. (Cohen EP, Regner K, Fish BL, Moulder JE) J Pathol 2000 Mar;190(4):484-8 PMID: 10699999 SCOPUS ID: 2-s2.0-0034020686 03/04/2000 17 Citations
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