Sex differences in hippocampal function. J Neurosci Res 2017 Jan 02;95(1-2):539-562
Date
11/22/2016Pubmed ID
27870401DOI
10.1002/jnr.23864Scopus ID
2-s2.0-84994316332 (requires institutional sign-in at Scopus site) 125 CitationsAbstract
Sex differences in the function of the hippocampus have been observed in numerous mammalian species. However, the magnitude, extent, and specificity of these differences are unclear because they can depend on factors including age, methodology, and environment. This Review will discuss seminal studies examining sex differences in hippocampal memory, neuronal morphology, synaptic plasticity, and cell signaling in humans and rodents. We also describe possible organizational and activational effects of sex steroid hormones during early development, puberty, and adulthood that may lead to sex differences observed in the hippocampus. We conclude by discussing the implications of sex differences in hippocampal function for mental health. © 2016 Wiley Periodicals, Inc.
Author List
Koss WA, Frick KMAuthor
Karyn Frick BA,MA,PhD Professor in the Psychology department at University of Wisconsin - MilwaukeeMESH terms used to index this publication - Major topics in bold
AnimalsFemale
Hippocampus
Humans
Male
Memory
Neuronal Plasticity
Sex Characteristics
