Cellular signalling: STIMulating calcium entry. Curr Biol 2005 Jul 12;15(13):R493-5
Date
07/12/2005Pubmed ID
16005278DOI
10.1016/j.cub.2005.06.035Scopus ID
2-s2.0-21844432949 (requires institutional sign-in at Scopus site) 16 CitationsAbstract
The molecular identity of the signal coupling intracellular Ca(2+) store depletion to the activation of Ca(2+) entry has long resisted exposure. Two recent studies independently implicate the STIM protein family as essential components in this coupling. These data provide new impetus to resolve how store Ca(2+) content is sensed and communicated to store-operated Ca(2+) channels at the cell surface.
Author List
Marchant JSAuthor
Jonathan S. Marchant PhD Chair, Professor in the Cell Biology, Neurobiology and Anatomy department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Biological Transport, ActiveCalcium
Calcium Channels
Endoplasmic Reticulum
HeLa Cells
Humans
Ion Transport
Membrane Proteins
Models, Biological
Neoplasm Proteins
RNA Interference
Signal Transduction
Stromal Interaction Molecule 1