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Cellular signalling: STIMulating calcium entry. Curr Biol 2005 Jul 12;15(13):R493-5

Date

07/12/2005

Pubmed ID

16005278

DOI

10.1016/j.cub.2005.06.035

Scopus ID

2-s2.0-21844432949   14 Citations

Abstract

The molecular identity of the signal coupling intracellular Ca(2+) store depletion to the activation of Ca(2+) entry has long resisted exposure. Two recent studies independently implicate the STIM protein family as essential components in this coupling. These data provide new impetus to resolve how store Ca(2+) content is sensed and communicated to store-operated Ca(2+) channels at the cell surface.

Author List

Marchant JS

Author

Jonathan S. Marchant PhD Chair, Professor in the Cell Biology, Neurobiology and Anatomy department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Biological Transport, Active
Calcium
Calcium Channels
Endoplasmic Reticulum
HeLa Cells
Humans
Ion Transport
Membrane Proteins
Models, Biological
Neoplasm Proteins
RNA Interference
Signal Transduction
Stromal Interaction Molecule 1
jenkins-FCD Prod-482 91ad8a360b6da540234915ea01ff80e38bfdb40a