Key Components of Pain Management for Children and Adults with Sickle Cell Disease. Hematol Oncol Clin North Am 2018 Jun;32(3):535-550
Date
05/08/2018Pubmed ID
29729787Pubmed Central ID
PMC6800257DOI
10.1016/j.hoc.2018.01.014Scopus ID
2-s2.0-85046430141 (requires institutional sign-in at Scopus site) 39 CitationsAbstract
Sickle cell disease pain manifests as severe acute pain episodes and a debilitating chronic pain syndrome. Acute pain episodes are the most common reason for health care use; however, acute pain episodes are also frequently managed at home. Chronic pain syndrome develops in 30% to 40% of individuals with sickle cell disease, with an increasing incidence and severity with age. We review the critical aspects of pain management that are integral to the comprehensive approach to sickle cell disease pain and are rooted in the biopsychosocial model. The review focuses on opioid pharmacology and psychosocial comorbidities.
Author List
Brandow AM, DeBaun MRAuthor
Amanda Brandow DO Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultAnemia, Sickle Cell
Child
Chronic Pain
Humans
Pain Management
Syndrome