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Key Components of Pain Management for Children and Adults with Sickle Cell Disease. Hematol Oncol Clin North Am 2018 Jun;32(3):535-550

Date

05/08/2018

Pubmed ID

29729787

Pubmed Central ID

PMC6800257

DOI

10.1016/j.hoc.2018.01.014

Scopus ID

2-s2.0-85046430141 (requires institutional sign-in at Scopus site)   39 Citations

Abstract

Sickle cell disease pain manifests as severe acute pain episodes and a debilitating chronic pain syndrome. Acute pain episodes are the most common reason for health care use; however, acute pain episodes are also frequently managed at home. Chronic pain syndrome develops in 30% to 40% of individuals with sickle cell disease, with an increasing incidence and severity with age. We review the critical aspects of pain management that are integral to the comprehensive approach to sickle cell disease pain and are rooted in the biopsychosocial model. The review focuses on opioid pharmacology and psychosocial comorbidities.

Author List

Brandow AM, DeBaun MR

Author

Amanda Brandow DO Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adult
Anemia, Sickle Cell
Child
Chronic Pain
Humans
Pain Management
Syndrome