Faculty Collaboration Database

Oral prophylaxis and its effects on halitosis-associated and inflammatory parameters in patients with chronic periodontitis. Int J Dent Hyg 2014 Aug;12(3):199-207

Date

12/10/2013

Pubmed ID

24314016

DOI

10.1111/idh.12063

Scopus ID

2-s2.0-84903990850 (requires institutional sign-in at Scopus site)   15 Citations

Abstract

OBJECTIVE: A controlled clinical trial was conducted to evaluate the effects of oral prophylaxis on halitosis-associated, immunological and microbiological parameters.

METHODS: Thirty subjects were included in this controlled clinical trial (patients with generalized chronic periodontitis and controls without clinical attachment loss; each n = 15). Before oral prophylaxis and 14 days after (including tongue cleaning) volatile sulphur compounds (VSC), organoleptic scores and a tongue coating index were evaluated. The levels of IL-1β, IL-8, IL-10 and MMP-8 were measured in GCF, and also major periodontal pathogens were detected. Data were statistically analysed using anova and paired t-test.

RESULTS: Supragingival plaque and calculus removal with combined tongue cleaning was able to reduce significantly (P < 0.05) the VSC values in both groups (no significant differences between both groups). Two weeks after periodontal debridement, the VSC values were observed in the periodontitis group, but not in the control group, similar to the baseline values. The difference between the groups was statistically significant (P < 0.05). Only a repeated prophylaxis session in the periodontitis group was able to reduce VSC values significantly in comparison with baseline (P < 0.05). Organoleptic scores (10 and 30 cm) were significantly different (P < 0.05) between both groups before and after the treatment. Periodontal pathogens and host-derived markers were not significantly affected by a single prophylaxis session.

CONCLUSIONS: Oral prophylaxis may result in a significant decrease in VSC values. However, in periodontal diseases, a more complex treatment seems to be necessary.

Author List

Guentsch A, Pfister W, Cachovan G, Raschke G, Kuepper H, Schaefer O, Eick S

Author

Arndt Geuntsch in the CTSI department at Medical College of Wisconsin - CTSI

MESH terms used to index this publication - Major topics in bold

Adult
Aged
Aggregatibacter actinomycetemcomitans
Bacteroides
Chronic Periodontitis
Dental Calculus
Dental Plaque
Dental Prophylaxis
Female
Follow-Up Studies
Gingival Crevicular Fluid
Halitosis
Humans
Interleukin-10
Interleukin-1beta
Interleukin-8
Male
Matrix Metalloproteinase 8
Middle Aged
Oral Hygiene
Periodontal Debridement
Porphyromonas gingivalis
Sulfur Compounds
Tongue
Treponema denticola
Volatile Organic Compounds
Young Adult