Faculty Collaboration Database

Ganglioglioma in a Survivor of Infantile Glioblastoma. J Pediatr Hematol Oncol 2020 Jan;42(1):e56-e60

Date

01/25/2019

Pubmed ID

30676438

DOI

10.1097/MPH.0000000000001417

Scopus ID

2-s2.0-85060368706 (requires institutional sign-in at Scopus site)   2 Citations

Abstract

Congenital tumors account for 2% to 4% of all pediatric central nervous system tumors. Glioblastoma multiforme (GBM) represents a small subset of these tumors. Despite harboring histologic features similar to older patients, infants with GBM exhibit improved survival and respond more favorably to surgery and chemotherapy. To highlight this tumor's unique behavior, we report the case of a survivor of infantile GBM who developed a recurrent tumor in the surgical bed 6 months after diagnosis. The tumor was ultimately resected and was a ganglioglioma. This case shows both a favorable clinical outcome to an infantile GBM and this tumor's natural history.

Author List

Scheuermann A, Belongia M, Lawlor MW, Suchi M, Kaufman B, Vasudevaraja V, Serrano J, Snuderl M, Knipstein J

Authors

Michael W. Lawlor MD, PhD Adjunct Professor in the Pathology department at Medical College of Wisconsin
Mariko Suchi MD, PhD Associate Professor in the Pathology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Brain Neoplasms
Cancer Survivors
Child, Preschool
Female
Ganglioglioma
Glioblastoma
Humans
Neoplasm Recurrence, Local