Medical College of Wisconsin
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Michael W. Lawlor MD, PhD

Michael W. Lawlor MD, PhD profile photo picture

Professor

Institution: Medical College of Wisconsin
Department: Pathology
Division: Administration
Program: Pediatrics

Member of the Neuroscience Research Center


Publications (88)

  • Tetraspanin CD82 is necessary for muscle stem cell activation and supports dystrophic muscle function (Hall A, Fontelonga T, Wright A, Bugda Gwilt K, Widrick J, Pasut A, Villa F, Miranti CK, Gibbs D, Jiang E, Meng H, Lawlor MW, Gussoni E) Skeletal Muscle December 2020;10(1) SCOPUS ID: 2-s2.0-85096675863 12/01/2020    
  • Duchenne muscular dystrophy (DMD) cardiomyocyte-secreted exosomes promote the pathogenesis of DMD-associated cardiomyopathy. (Gartz M, Lin CW, Sussman MA, Lawlor MW, Strande JL) Dis Model Mech 2020 11 13;13(11) PMID: 33188007 PMCID: PMC7673361 SCOPUS ID: 2-s2.0-85096154674 11/15/2020       2 Citations
  • rAAV-related therapy fully rescues myonuclear and myofilament function in X-linked myotubular myopathy. (Ross JA, Tasfaout H, Levy Y, Morgan J, Cowling BS, Laporte J, Zanoteli E, Romero NB, Lowe DA, Jungbluth H, Lawlor MW, Mack DL, Ochala J) Acta Neuropathol Commun 2020 10 19;8(1):167 PMID: 33076971 PMCID: PMC7574461 SCOPUS ID: 2-s2.0-85092799337 10/21/2020    
  • Regulatory T Cells Contribute to Resistance against Lyme Arthritis. (Siebers EM, Liedhegner ES, Lawlor MW, Schell RF, Nardelli DT) Infect Immun 2020 10 19;88(11) PMID: 32778610 PMCID: PMC7573436 SCOPUS ID: 2-s2.0-85093883170 08/12/2020       1 Citation
  • Drug-impregnated, pressurized gas expanded liquid-processed alginate hydrogel scaffolds for accelerated burn wound healing. (Johnson KA, Muzzin N, Toufanian S, Slick RA, Lawlor MW, Seifried B, Moquin P, Latulippe D, Hoare T) Acta Biomater 2020 08;112:101-111 PMID: 32522716 SCOPUS ID: 2-s2.0-85086394204 06/12/2020       3 Citations
  • Conference report on contractures in musculoskeletal and neurological conditions. (Nuckolls GH, Kinnett K, Dayanidhi S, Domenighetti AA, Duong T, Hathout Y, Lawlor MW, Lee SSM, Magnusson SP, McDonald CM, McNally EM, Miller NF, Olwin BB, Raghavan P, Roberts TJ, Rutkove SB, Sarwark JF, Senesac CR, Vogel LF, Walter GA, Willcocks RJ, Rymer WZ, Lieber RL) Muscle Nerve 2020 06;61(6):740-744 PMID: 32108365 PMCID: PMC7229996 SCOPUS ID: 2-s2.0-85081550208 02/29/2020       2 Citations
  • Nebulin nemaline myopathy recapitulated in a compound heterozygous mouse model with both a missense and a nonsense mutation in Neb. (Laitila JM, McNamara EL, Wingate CD, Goullee H, Ross JA, Taylor RL, van der Pijl R, Griffiths LM, Harries R, Ravenscroft G, Clayton JS, Sewry C, Lawlor MW, Ottenheijm CAC, Bakker AJ, Ochala J, Laing NG, Wallgren-Pettersson C, Pelin K, Nowak KJ) Acta Neuropathol Commun 2020 02 17;8(1):18 PMID: 32066503 PMCID: PMC7027239 SCOPUS ID: 2-s2.0-85079597530 02/19/2020       2 Citations
  • AAV-Mediated Gene Transfer Restores a Normal Muscle Transcriptome in a Canine Model of X-Linked Myotubular Myopathy. (Dupont JB, Guo J, Renaud-Gabardos E, Poulard K, Latournerie V, Lawlor MW, Grange RW, Gray JT, Buj-Bello A, Childers MK, Mack DL) Mol Ther 2020 02 05;28(2):382-393 PMID: 31784415 PMCID: PMC7000997 SCOPUS ID: 2-s2.0-85075895675 12/01/2019       5 Citations
  • Disease burden of Crigler-Najjar syndrome: Systematic review and future perspectives. (Dhawan A, Lawlor MW, Mazariegos GV, McKiernan P, Squires JE, Strauss KA, Gupta D, James E, Prasad S) J Gastroenterol Hepatol 2020 Apr;35(4):530-543 PMID: 31495946 SCOPUS ID: 2-s2.0-85074581875 09/10/2019       3 Citations
  • NOD-like receptor protein 3 inflammasome drives postoperative mechanical pain in a sex-dependent manner. (Cowie AM, Menzel AD, O'Hara C, Lawlor MW, Stucky CL) Pain 2019 08;160(8):1794-1816 PMID: 31335648 PMCID: PMC6662742 SCOPUS ID: 2-s2.0-85069147648 07/25/2019       12 Citations
  • Intracranial Extraskeletal Mesenchymal Chondrosarcoma: Case Report and Review of the Literature of Reported Cases in Adults and Children. (Shabani S, Kaushal M, Kaufman B, Knipstein J, Lawlor MW, Lew S, Foy A) World Neurosurg 2019 Sep;129:302-310 PMID: 31158544 SCOPUS ID: 2-s2.0-85068562842 06/04/2019       1 Citation
  • Tissue Response and Biodistribution of Injectable Cellulose Nanocrystal Composite Hydrogels (De France KJ, Badv M, Dorogin J, Siebers E, Panchal V, Babi M, Moran-Mirabal J, Lawlor M, Cranston ED, Hoare T) ACS Biomaterials Science and Engineering 13 May 2019;5(5):2235-2246 SCOPUS ID: 2-s2.0-85065644124 05/13/2019    
  • NOD-like receptor protein 3 inflammasome drives postoperative mechanical pain in a sex-dependent manner. (Cowie AM, Menzel AD, O'Hara C, Lawlor MW, Stucky CL) Pain 2019 Mar 08 PMID: 30870320 SCOPUS ID: 2-s2.0-85069147648 03/15/2019       15 Citations
  • Maintaining extraembryonic expression allows generation of mice with severe tissue factor pathway inhibitor deficiency. (Castillo MM, Yang Q, Zhan M, Pan AY, Lawlor MW, Mast AE, Sood R) Blood Adv 2019 02 12;3(3):489-498 PMID: 30755437 PMCID: PMC6373739 SCOPUS ID: 2-s2.0-85061474836 02/14/2019       1 Citation
  • Severe Neonatal RYR1 Myopathy With Pathological Features of Congenital Muscular Dystrophy. (Helbling DC, Mendoza D, McCarrier J, Vanden Avond MA, Harmelink MM, Barkhaus PE, Basel D, Lawlor MW) J Neuropathol Exp Neurol 2019 03 01;78(3):283-287 PMID: 30715496 PMCID: PMC6380315 SCOPUS ID: 2-s2.0-85063882669 02/05/2019       2 Citations
  • Ganglioglioma in a Survivor of Infantile Glioblastoma. (Scheuermann A, Belongia M, Lawlor MW, Suchi M, Kaufman B, Vasudevaraja V, Serrano J, Snuderl M, Knipstein J) J Pediatr Hematol Oncol 2020 01;42(1):e56-e60 PMID: 30676438 SCOPUS ID: 2-s2.0-85060368706 01/25/2019       2 Citations
  • Myostatin Inhibition Using ActRIIB-mFc Does Not Produce Weight Gain or Strength in the Nebulin Conditional KO Mouse. (Tinklenberg JA, Siebers EM, Beatka MJ, Fickau BA, Ayres S, Meng H, Yang L, Simpson P, Granzier HL, Lawlor MW) J Neuropathol Exp Neurol 2019 02 01;78(2):130-139 PMID: 30597051 PMCID: PMC6804412 SCOPUS ID: 2-s2.0-85060009246 01/01/2019       4 Citations
  • Injectable and Degradable Poly(Oligoethylene glycol methacrylate) Hydrogels with Tunable Charge Densities as Adhesive Peptide-Free Cell Scaffolds (Bakaic E, Smeets NMB, Badv M, Dodd M, Barrigar O, Siebers E, Lawlor M, Sheardown H, Hoare T) ACS Biomaterials Science and Engineering 12 November 2018;4(11):3713-3725 SCOPUS ID: 2-s2.0-85056870867 11/12/2018    
  • Pathological Issues in Dystrophinopathy in the Age of Genetic Therapies. (Shahnoor N, Siebers EM, Brown KJ, Lawlor MW) Annu Rev Pathol 2019 01 24;14:105-126 PMID: 30148687 SCOPUS ID: 2-s2.0-85060528542 08/28/2018       1 Citation
  • Use Of Ankle Immobilization In Evaluating Treatments To Promote Longitudinal Muscle Growth In Mice. (Tinklenberg J, Beatka M, Bain JLW, Siebers EM, Meng H, Pearsall RS, Lawlor MW, Riley DA) Muscle Nerve 2018 11;58(5):718-725 PMID: 29981243 PMCID: PMC6246800 SCOPUS ID: 2-s2.0-85054337476 07/08/2018       1 Citation
  • TNNT1 nemaline myopathy: natural history and therapeutic frontier. (Fox MD, Carson VJ, Feng HZ, Lawlor MW, Gray JT, Brigatti KW, Jin JP, Strauss KA) Hum Mol Genet 2018 09 15;27(18):3272-3282 PMID: 29931346 PMCID: PMC6121192 SCOPUS ID: 2-s2.0-85055339707 06/23/2018       8 Citations
  • Sdha+/- Rats Display Minimal Muscle Pathology Without Significant Behavioral or Biochemical Abnormalities. (Siebers EM, Choi MJ, Tinklenberg JA, Beatka MJ, Ayres S, Meng H, Helbling DC, Takizawa A, Bennett B, Garces AM, Dias Duarte Machado LG, Dimmock D, Dwinell MR, Geurts AM, Lawlor MW) J Neuropathol Exp Neurol 2018 08 01;77(8):665-672 PMID: 29850869 PMCID: PMC6044411 SCOPUS ID: 2-s2.0-85054028838 06/01/2018       4 Citations
  • NINDS Common Data Elements for Congenital Muscular Dystrophy Clinical Research: A National Institute for Neurological Disorders and Stroke Project. (Lawlor MW, Iannaccone ST, Mathews K, Muntoni F, Alai-Hansen S, Odenkirchen JC, S Feldman R, CMD Working Group) J Neuromuscul Dis 2018;5(1):75-84 PMID: 29480213 SCOPUS ID: 2-s2.0-85043695419 02/27/2018    
  • Intravenous Administration of a MTMR2-Encoding AAV Vector Ameliorates the Phenotype of Myotubular Myopathy in Mice. (Danièle N, Moal C, Julien L, Marinello M, Jamet T, Martin S, Vignaud A, Lawlor MW, Buj-Bello A) J Neuropathol Exp Neurol 2018 04 01;77(4):282-295 PMID: 29408998 PMCID: PMC5939852 SCOPUS ID: 2-s2.0-85045070041 02/07/2018       7 Citations
  • Myostatin inhibition using mRK35 produces skeletal muscle growth and tubular aggregate formation in wild type and TgACTA1D286G nemaline myopathy mice. (Tinklenberg JA, Siebers EM, Beatka MJ, Meng H, Yang L, Zhang Z, Ross JA, Ochala J, Morris C, Owens JM, Laing NG, Nowak KJ, Lawlor MW) Hum Mol Genet 2018 02 15;27(4):638-648 PMID: 29293963 PMCID: PMC5886278 SCOPUS ID: 2-s2.0-85041501214 01/03/2018       13 Citations
  • Novel autosomal dominant TNNT1 mutation causing nemaline myopathy. (Konersman CG, Freyermuth F, Winder TL, Lawlor MW, Lagier-Tourenne C, Patel SB) Mol Genet Genomic Med 2017 11;5(6):678-691 PMID: 29178646 PMCID: PMC5702563 SCOPUS ID: 2-s2.0-85040707754 11/28/2017       10 Citations
  • Diaphragm Atrophy and Weakness in the Absence of Mitochondrial Dysfunction in the Critically Ill. (van den Berg M, Hooijman PE, Beishuizen A, de Waard MC, Paul MA, Hartemink KJ, van Hees HWH, Lawlor MW, Brocca L, Bottinelli R, Pellegrino MA, Stienen GJM, Heunks LMA, Wüst RCI, Ottenheijm CAC) Am J Respir Crit Care Med 2017 12 15;196(12):1544-1558 PMID: 28787181 PMCID: PMC5754442 SCOPUS ID: 2-s2.0-85029879309 08/09/2017       20 Citations
  • Host interleukin 6 production regulates inflammation but not tryptophan metabolism in the brain during murine GVHD. (Belle L, Zhou V, Stuhr KL, Beatka M, Siebers EM, Knight JM, Lawlor MW, Weaver C, Hashizume M, Hillard CJ, Drobyski WR) JCI Insight 2017 Jul 20;2(14) PMID: 28724796 PMCID: PMC5518565 SCOPUS ID: 2-s2.0-85033974707 07/21/2017       6 Citations
  • Long-term effects of systemic gene therapy in a canine model of myotubular myopathy. (Elverman M, Goddard MA, Mack D, Snyder JM, Lawlor MW, Meng H, Beggs AH, Buj-Bello A, Poulard K, Marsh AP, Grange RW, Kelly VE, Childers MK) Muscle Nerve 2017 Nov;56(5):943-953 PMID: 28370029 PMCID: PMC5620115 SCOPUS ID: 2-s2.0-85019894779 04/04/2017       29 Citations
  • Systemic AAV8-Mediated Gene Therapy Drives Whole-Body Correction of Myotubular Myopathy in Dogs. (Mack DL, Poulard K, Goddard MA, Latournerie V, Snyder JM, Grange RW, Elverman MR, Denard J, Veron P, Buscara L, Le Bec C, Hogrel JY, Brezovec AG, Meng H, Yang L, Liu F, O'Callaghan M, Gopal N, Kelly VE, Smith BK, Strande JL, Mavilio F, Beggs AH, Mingozzi F, Lawlor MW, Buj-Bello A, Childers MK) Mol Ther 2017 04 05;25(4):839-854 PMID: 28237839 PMCID: PMC5383631 SCOPUS ID: 2-s2.0-85016950473 02/27/2017       50 Citations
  • Macrocyclic MEK1/2 inhibitor with efficacy in a mouse model of cardiomyopathy caused by lamin A/C gene mutation. (Wu W, Chordia MD, Hart BP, Kumarasinghe ES, Ji MK, Bhargava A, Lawlor MW, Shin JY, Sera F, Homma S, Muchir A, Khire UR, Worman HJ) Bioorg Med Chem 2017 02 01;25(3):1004-1013 PMID: 28011205 PMCID: PMC5291759 SCOPUS ID: 2-s2.0-85008155389 12/25/2016       13 Citations
  • Phosphatidylinositol 3-kinase inhibition restores Ca2+ release defects and prolongs survival in myotubularin-deficient mice. (Kutchukian C, Lo Scrudato M, Tourneur Y, Poulard K, Vignaud A, Berthier C, Allard B, Lawlor MW, Buj-Bello A, Jacquemond V) Proc Natl Acad Sci U S A 2016 12 13;113(50):14432-14437 PMID: 27911767 PMCID: PMC5167204 SCOPUS ID: 2-s2.0-85005992133 12/03/2016       18 Citations
  • Presentation and Diagnostic Evaluation of Mitochondrial Disease. (Dimmock DP, Lawlor MW) Pediatr Clin North Am 2017 Feb;64(1):161-171 PMID: 27894442 PMCID: PMC5130109 SCOPUS ID: 2-s2.0-84998774602 11/30/2016       9 Citations
  • CD82 Is a Marker for Prospective Isolation of Human Muscle Satellite Cells and Is Linked to Muscular Dystrophies. (Alexander MS, Rozkalne A, Colletta A, Spinazzola JM, Johnson S, Rahimov F, Meng H, Lawlor MW, Estrella E, Kunkel LM, Gussoni E) Cell Stem Cell 2016 12 01;19(6):800-807 PMID: 27641304 PMCID: PMC5135584 SCOPUS ID: 2-s2.0-84994721676 09/20/2016       44 Citations
  • In Reply. (Lawlor MW) Arch Pathol Lab Med 2016 09;140(9):879 PMID: 27575262 08/31/2016    
  • Treatment with ActRIIB-mFc Produces Myofiber Growth and Improves Lifespan in the Acta1 H40Y Murine Model of Nemaline Myopathy. (Tinklenberg J, Meng H, Yang L, Liu F, Hoffmann RG, Dasgupta M, Allen KP, Beggs AH, Hardeman EC, Pearsall RS, Fitts RH, Lawlor MW) Am J Pathol 2016 06;186(6):1568-81 PMID: 27102768 PMCID: PMC4901141 SCOPUS ID: 2-s2.0-84969848977 04/23/2016       11 Citations
  • Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes. (Zappia KJ, Garrison SR, Palygin O, Weyer AD, Barabas ME, Lawlor MW, Staruschenko A, Stucky CL) PLoS One 2016;11(3):e0151602 PMID: 26978657 PMCID: PMC4792390 SCOPUS ID: 2-s2.0-84961820405 03/16/2016       17 Citations
  • Skeletal Muscle Pathology in X-Linked Myotubular Myopathy: Review With Cross-Species Comparisons. (Lawlor MW, Beggs AH, Buj-Bello A, Childers MK, Dowling JJ, James ES, Meng H, Moore SA, Prasad S, Schoser B, Sewry CA) J Neuropathol Exp Neurol 2016 Feb;75(2):102-10 PMID: 26823526 PMCID: PMC4765322 SCOPUS ID: 2-s2.0-84960448751 01/30/2016       30 Citations
  • Potentially diagnostic electron paramagnetic resonance spectra elucidate the underlying mechanism of mitochondrial dysfunction in the deoxyguanosine kinase deficient rat model of a genetic mitochondrial DNA depletion syndrome. (Bennett B, Helbling D, Meng H, Jarzembowski J, Geurts AM, Friederich MW, Van Hove JLK, Lawlor MW, Dimmock DP) Free Radic Biol Med 2016 Mar;92:141-151 PMID: 26773591 PMCID: PMC5047058 SCOPUS ID: 2-s2.0-84957568061 01/17/2016       13 Citations
  • Erratum to Muscle pathology, limb strength, walking gait, respiratory function and neurological impairment establish disease progression in the p.N155K canine model of X-linked myotubular myopathy [Ann Transl Med, 3, 18 (2015) 262] (Goddard MA, Mack DL, Hogrel JY, Czerniecki SM, Kelly VE, Snyder JM, Grange RW, Lawlor MW, Smith BK, Beggs AH, Childers MK) Annals of Translational Medicine January 2016;4(1) SCOPUS ID: 2-s2.0-85006220535 01/01/2016    
  • Muscle pathology, limb strength, walking gait, respiratory function and neurological impairment establish disease progression in the p.N155K canine model of X-linked myotubular myopathy. (Goddard MA, Mack DL, Czerniecki SM, Kelly VE, Snyder JM, Grange RW, Lawlor MW, Smith BK, Beggs AH, Childers MK) Ann Transl Med 2015 Oct;3(18):262 PMID: 26605308 PMCID: PMC4630545 11/26/2015    
  • Common Data Elements for Muscle Biopsy Reporting. (Dastgir J, Rutkowski A, Alvarez R, Cossette SA, Yan K, Hoffmann RG, Sewry C, Hayashi YK, Goebel HH, Bonnemann C, Lawlor MW) Arch Pathol Lab Med 2016 Jan;140(1):51-65 PMID: 26132600 PMCID: PMC4975562 SCOPUS ID: 2-s2.0-84954289035 07/02/2015       11 Citations
  • Nebulin deficiency in adult muscle causes sarcomere defects and muscle-type-dependent changes in trophicity: novel insights in nemaline myopathy. (Li F, Buck D, De Winter J, Kolb J, Meng H, Birch C, Slater R, Escobar YN, Smith JE 3rd, Yang L, Konhilas J, Lawlor MW, Ottenheijm C, Granzier HL) Hum Mol Genet 2015 Sep 15;24(18):5219-33 PMID: 26123491 PMCID: PMC4550825 SCOPUS ID: 2-s2.0-84940663695 07/01/2015       36 Citations
  • Diaphragm muscle fiber weakness and ubiquitin-proteasome activation in critically ill patients. (Hooijman PE, Beishuizen A, Witt CC, de Waard MC, Girbes AR, Spoelstra-de Man AM, Niessen HW, Manders E, van Hees HW, van den Brom CE, Silderhuis V, Lawlor MW, Labeit S, Stienen GJ, Hartemink KJ, Paul MA, Heunks LM, Ottenheijm CA) Am J Respir Crit Care Med 2015 May 15;191(10):1126-38 PMID: 25760684 PMCID: PMC4451621 SCOPUS ID: 2-s2.0-84989782434 03/12/2015       87 Citations
  • BAG3 myofibrillar myopathy presenting with cardiomyopathy. (Konersman CG, Bordini BJ, Scharer G, Lawlor MW, Zangwill S, Southern JF, Amos L, Geddes GC, Kliegman R, Collins MP) Neuromuscul Disord 2015 May;25(5):418-22 PMID: 25728519 SCOPUS ID: 2-s2.0-84927912558 03/03/2015       44 Citations
  • Isolation and immortalization of patient-derived cell lines from muscle biopsy for disease modeling. (Robin JD, Wright WE, Zou Y, Cossette SC, Lawlor MW, Gussoni E) J Vis Exp 2015 Jan 18(95):52307 PMID: 25651101 PMCID: PMC4354544 SCOPUS ID: 2-s2.0-84921628370 02/05/2015       7 Citations
  • Whole-thorax irradiation induces hypoxic respiratory failure, pleural effusions and cardiac remodeling. (Medhora M, Gao F, Glisch C, Narayanan J, Sharma A, Harmann LM, Lawlor MW, Snyder LA, Fish BL, Down JD, Moulder JE, Strande JL, Jacobs ER) J Radiat Res 2015 Mar;56(2):248-60 PMID: 25368342 PMCID: PMC4380043 SCOPUS ID: 2-s2.0-84942308898 11/05/2014       27 Citations
  • Triadopathies: an emerging class of skeletal muscle diseases. (Dowling JJ, Lawlor MW, Dirksen RT) Neurotherapeutics 2014 Oct;11(4):773-85 PMID: 25168790 PMCID: PMC4391390 SCOPUS ID: 2-s2.0-84919781500 08/30/2014       37 Citations
  • Tissue triage and freezing for models of skeletal muscle disease. (Meng H, Janssen PM, Grange RW, Yang L, Beggs AH, Swanson LC, Cossette SA, Frase A, Childers MK, Granzier H, Gussoni E, Lawlor MW) J Vis Exp 2014 Jul 15(89) PMID: 25078247 PMCID: PMC4215994 08/01/2014    
  • Differential muscle hypertrophy is associated with satellite cell numbers and Akt pathway activation following activin type IIB receptor inhibition in Mtm1 p.R69C mice. (Lawlor MW, Viola MG, Meng H, Edelstein RV, Liu F, Yan K, Luna EJ, Lerch-Gaggl A, Hoffmann RG, Pierson CR, Buj-Bello A, Lachey JL, Pearsall S, Yang L, Hillard CJ, Beggs AH) Am J Pathol 2014 Jun;184(6):1831-42 PMID: 24726641 PMCID: PMC4044712 SCOPUS ID: 2-s2.0-84901020192 04/15/2014       19 Citations
  • Gene therapy prolongs survival and restores function in murine and canine models of myotubular myopathy. (Childers MK, Joubert R, Poulard K, Moal C, Grange RW, Doering JA, Lawlor MW, Rider BE, Jamet T, Danièle N, Martin S, Rivière C, Soker T, Hammer C, Van Wittenberghe L, Lockard M, Guan X, Goddard M, Mitchell E, Barber J, Williams JK, Mack DL, Furth ME, Vignaud A, Masurier C, Mavilio F, Moullier P, Beggs AH, Buj-Bello A) Sci Transl Med 2014 Jan 22;6(220):220ra10 PMID: 24452262 PMCID: PMC4105197 SCOPUS ID: 2-s2.0-84893427190 01/24/2014       89 Citations
  • Dystrophin-deficient cardiomyocytes derived from human urine: new biologic reagents for drug discovery. (Guan X, Mack DL, Moreno CM, Strande JL, Mathieu J, Shi Y, Markert CD, Wang Z, Liu G, Lawlor MW, Moorefield EC, Jones TN, Fugate JA, Furth ME, Murry CE, Ruohola-Baker H, Zhang Y, Santana LF, Childers MK) Stem Cell Res 2014 Mar;12(2):467-80 PMID: 24434629 PMCID: PMC3966181 SCOPUS ID: 2-s2.0-84892470978 01/18/2014       62 Citations
  • Congenital Myopathies (Lawlor MW, Pierson CR) Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms 1 January 2014:195-209 SCOPUS ID: 2-s2.0-85043273899 01/01/2014    
  • G-protein coupled receptor 56 promotes myoblast fusion through serum response factor- and nuclear factor of activated T-cell-mediated signalling but is not essential for muscle development in vivo. (Wu MP, Doyle JR, Barry B, Beauvais A, Rozkalne A, Piao X, Lawlor MW, Kopin AS, Walsh CA, Gussoni E) FEBS J 2013 Dec;280(23):6097-113 PMID: 24102982 PMCID: PMC3877849 SCOPUS ID: 2-s2.0-84888297031 10/10/2013       28 Citations
  • Recessive truncating titin gene, TTN, mutations presenting as centronuclear myopathy. (Ceyhan-Birsoy O, Agrawal PB, Hidalgo C, Schmitz-Abe K, DeChene ET, Swanson LC, Soemedi R, Vasli N, Iannaccone ST, Shieh PB, Shur N, Dennison JM, Lawlor MW, Laporte J, Markianos K, Fairbrother WG, Granzier H, Beggs AH) Neurology 2013 Oct 01;81(14):1205-14 PMID: 23975875 PMCID: PMC3795603 SCOPUS ID: 2-s2.0-84886409449 08/27/2013       119 Citations
  • Thin Filament Proteins: Nemaline and Related Congenital Myopathies (Lawlor MW, Beggs AH) Muscle Disease: Pathology and Genetics: Second Edition 8 July 2013:145-151 SCOPUS ID: 2-s2.0-85016891546 07/08/2013    
  • Deleting exon 55 from the nebulin gene induces severe muscle weakness in a mouse model for nemaline myopathy. (Ottenheijm CA, Buck D, de Winter JM, Ferrara C, Piroddi N, Tesi C, Jasper JR, Malik FI, Meng H, Stienen GJ, Beggs AH, Labeit S, Poggesi C, Lawlor MW, Granzier H) Brain 2013 Jun;136(Pt 6):1718-31 PMID: 23715096 PMCID: PMC3673460 05/30/2013    
  • Troponin activator augments muscle force in nemaline myopathy patients with nebulin mutations. (de Winter JM, Buck D, Hidalgo C, Jasper JR, Malik FI, Clarke NF, Stienen GJ, Lawlor MW, Beggs AH, Ottenheijm CA, Granzier H) J Med Genet 2013 Jun;50(6):383-92 PMID: 23572184 PMCID: PMC3865762 SCOPUS ID: 2-s2.0-84878843972 04/11/2013       32 Citations
  • Selenoprotein N deficiency in mice is associated with abnormal lung development. (Moghadaszadeh B, Rider BE, Lawlor MW, Childers MK, Grange RW, Gupta K, Boukedes SS, Owen CA, Beggs AH) FASEB J 2013 Apr;27(4):1585-99 PMID: 23325319 PMCID: PMC3606527 SCOPUS ID: 2-s2.0-84875702360 01/18/2013       24 Citations
  • Enzyme replacement therapy rescues weakness and improves muscle pathology in mice with X-linked myotubular myopathy. (Lawlor MW, Armstrong D, Viola MG, Widrick JJ, Meng H, Grange RW, Childers MK, Hsu CP, O'Callaghan M, Pierson CR, Buj-Bello A, Beggs AH) Hum Mol Genet 2013 Apr 15;22(8):1525-38 PMID: 23307925 PMCID: PMC3605830 SCOPUS ID: 2-s2.0-84875766052 01/12/2013       52 Citations
  • Large duplication in MTM1 associated with myotubular myopathy. (Amburgey K, Lawlor MW, Del Gaudio D, Cheng YW, Fitzpatrick C, Minor A, Li X, Aughton D, Das S, Beggs AH, Dowling JJ) Neuromuscul Disord 2013 Mar;23(3):214-8 PMID: 23273872 PMCID: PMC3594803 SCOPUS ID: 2-s2.0-85027946146 01/01/2013       8 Citations
  • Myotubularin-deficient myoblasts display increased apoptosis, delayed proliferation, and poor cell engraftment. (Lawlor MW, Alexander MS, Viola MG, Meng H, Joubert R, Gupta V, Motohashi N, Manfready RA, Hsu CP, Huang P, Buj-Bello A, Kunkel LM, Beggs AH, Gussoni E) Am J Pathol 2012 Sep;181(3):961-8 PMID: 22841819 PMCID: PMC3432426 SCOPUS ID: 2-s2.0-84865267643 07/31/2012       28 Citations
  • Oxygen gas-filled microparticles provide intravenous oxygen delivery. (Kheir JN, Scharp LA, Borden MA, Swanson EJ, Loxley A, Reese JH, Black KJ, Velazquez LA, Thomson LM, Walsh BK, Mullen KE, Graham DA, Lawlor MW, Brugnara C, Bell DC, McGowan FX Jr) Sci Transl Med 2012 Jun 27;4(140):140ra88 PMID: 22745438 SCOPUS ID: 2-s2.0-84863227471 06/30/2012       58 Citations
  • Thermoresponsive nanogels for prolonged duration local anesthesia. (Hoare T, Young S, Lawlor MW, Kohane DS) Acta Biomater 2012 Oct;8(10):3596-605 PMID: 22732383 PMCID: PMC3429626 SCOPUS ID: 2-s2.0-84865484651 06/27/2012       37 Citations
  • Toxicogenomic analysis of a sustained release local anesthetic delivery system. (Shichor I, Shomron N, Lawlor MW, Bae SA, Zoldan J, Langer R, Kohane DS) Biomaterials 2012 May;33(13):3586-93 PMID: 22341215 PMCID: PMC3288387 SCOPUS ID: 2-s2.0-84857441486 02/22/2012       6 Citations
  • Nanogel scavengers for drugs: local anesthetic uptake by thermoresponsive nanogels. (Hoare T, Sivakumaran D, Stefanescu CF, Lawlor MW, Kohane DS) Acta Biomater 2012 Apr;8(4):1450-8 PMID: 22244983 PMCID: PMC3289739 SCOPUS ID: 2-s2.0-84857781615 01/17/2012       19 Citations
  • Erratum: Elasticity and safety of alkoxyethyl cyanoacrylate tissue adhesives (Acta Biomaterialia (2011) 7 (3150-3157)) (Mizrahi B, Stefanescu CF, Yang C, Lawlor MW, Ko D, Langer R, Kohane DS) Acta Biomaterialia January 2012;8(1):458 SCOPUS ID: 2-s2.0-84855917457 01/01/2012    
  • Modeling the human MTM1 p.R69C mutation in murine Mtm1 results in exon 4 skipping and a less severe myotubular myopathy phenotype. (Pierson CR, Dulin-Smith AN, Durban AN, Marshall ML, Marshall JT, Snyder AD, Naiyer N, Gladman JT, Chandler DS, Lawlor MW, Buj-Bello A, Dowling JJ, Beggs AH) Hum Mol Genet 2012 Feb 15;21(4):811-25 PMID: 22068590 PMCID: PMC3263994 SCOPUS ID: 2-s2.0-84856350401 11/10/2011       38 Citations
  • An in vivo rodent model of contraction-induced injury in the quadriceps muscle. (Pratt SJP, Lawlor MW, Shah SB, Lovering RM) Injury 2012 06;43(6):788-93 PMID: 22001505 PMCID: PMC3310278 SCOPUS ID: 2-s2.0-84860740259 10/18/2011       15 Citations
  • Polydopamine coatings enhance biointegration of a model polymeric implant (Jeong KJ, Wang L, Stefanescu CF, Lawlor MW, Polat J, Dohlman CH, Langer RS, Kohane DS) Soft Matter 21 September 2011;7(18):8305-8312 SCOPUS ID: 2-s2.0-80052529624 09/21/2011    
  • Novel mutations in NEB cause abnormal nebulin expression and markedly impaired muscle force generation in severe nemaline myopathy. (Lawlor MW, Ottenheijm CA, Lehtokari VL, Cho K, Pelin K, Wallgren-Pettersson C, Granzier H, Beggs AH) Skelet Muscle 2011 Jun 20;1(1):23 PMID: 21798101 PMCID: PMC3156646 07/30/2011    
  • Elasticity and safety of alkoxyethyl cyanoacrylate tissue adhesives. (Mizrahi B, Stefanescu CF, Yang C, Lawlor MW, Ko D, Langer R, Kohane DS) Acta Biomater 2011 Aug;7(8):3150-7 PMID: 21569875 PMCID: PMC4059060 SCOPUS ID: 2-s2.0-79959844652 05/17/2011       47 Citations
  • Erratum: Prolonged duration local anesthesia with minimal toxicity (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, 17, (7125-7130) DOI: 10.1073/pnas.0900598106) (Epstein-Barash H, Shichor I, Kwon AH, Hall S, Lawlor MW, Langer R, Kohane DS) Proceedings of the National Academy of Sciences of the United States of America 8 March 2011;108(10):4264 SCOPUS ID: 2-s2.0-79952747712 03/08/2011    
  • Changes in cross-bridge cycling underlie muscle weakness in patients with tropomyosin 3-based myopathy. (Ottenheijm CA, Lawlor MW, Stienen GJ, Granzier H, Beggs AH) Hum Mol Genet 2011 May 15;20(10):2015-25 PMID: 21357678 PMCID: PMC3080611 SCOPUS ID: 2-s2.0-79955371742 03/02/2011       52 Citations
  • Inhibition of activin receptor type IIB increases strength and lifespan in myotubularin-deficient mice (The American Journal of Pathology (2011) 178 (784-793)) (Lawlor MW, Read BP, Edelstein R, Yang N, Pierson CR, Stein MJ, Wermer-Colan A, Buj-Bello A, Lachey JL, Seehra JS, Beggs AH) American Journal of Pathology March 2011;178(3):1406 SCOPUS ID: 2-s2.0-79952741382 03/01/2011    
  • Inhibition of activin receptor type IIB increases strength and lifespan in myotubularin-deficient mice. (Lawlor MW, Read BP, Edelstein R, Yang N, Pierson CR, Stein MJ, Wermer-Colan A, Buj-Bello A, Lachey JL, Seehra JS, Beggs AH) Am J Pathol 2011 Feb;178(2):784-93 PMID: 21281811 PMCID: PMC3069865 02/02/2011    
  • Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene. (Zhou Y, Cheunsuchon P, Nakayama Y, Lawlor MW, Zhong Y, Rice KA, Zhang L, Zhang X, Gordon FE, Lidov HG, Bronson RT, Klibanski A) Development 2010 Aug;137(16):2643-52 PMID: 20610486 PMCID: PMC2910384 SCOPUS ID: 2-s2.0-77955744813 07/09/2010       87 Citations
  • Functional muscle analysis of the Tcap knockout mouse. (Markert CD, Meaney MP, Voelker KA, Grange RW, Dalley HW, Cann JK, Ahmed M, Bishwokarma B, Walker SJ, Yu SX, Brown M, Lawlor MW, Beggs AH, Childers MK) Hum Mol Genet 2010 Jun 01;19(11):2268-83 PMID: 20233748 PMCID: PMC2865379 SCOPUS ID: 2-s2.0-77953511024 03/18/2010       22 Citations
  • Neuropathology of a fatal case of posterior reversible encephalopathy syndrome. (Kheir JN, Lawlor MW, Ahn ES, Lehmann L, Riviello JJ, Silvera VM, McManus M, Folkerth RD) Pediatr Dev Pathol 2010 Sep-Oct;13(5):397-403 PMID: 20158377 SCOPUS ID: 2-s2.0-79952197856 02/18/2010       20 Citations
  • Mutations of tropomyosin 3 (TPM3) are common and associated with type 1 myofiber hypotrophy in congenital fiber type disproportion. (Lawlor MW, Dechene ET, Roumm E, Geggel AS, Moghadaszadeh B, Beggs AH) Hum Mutat 2010 Feb;31(2):176-83 PMID: 19953533 PMCID: PMC2815199 SCOPUS ID: 2-s2.0-75149179143 12/03/2009       53 Citations
  • Prolonged duration local anesthesia with minimal toxicity. (Epstein-Barash H, Shichor I, Kwon AH, Hall S, Lawlor MW, Langer R, Kohane DS) Proc Natl Acad Sci U S A 2009 Apr 28;106(17):7125-30 PMID: 19365067 PMCID: PMC2678453 SCOPUS ID: 2-s2.0-66349108420 04/15/2009       104 Citations
  • Effect of chemical permeation enhancers on nerve blockade. (Simons EJ, Bellas E, Lawlor MW, Kohane DS) Mol Pharm 2009 Jan-Feb;6(1):265-73 PMID: 19105721 PMCID: PMC2646764 SCOPUS ID: 2-s2.0-62649146532 12/25/2008       29 Citations
  • Three-dimensional conductive constructs for nerve regeneration. (George PM, Saigal R, Lawlor MW, Moore MJ, LaVan DA, Marini RP, Selig M, Makhni M, Burdick JA, Langer R, Kohane DS) J Biomed Mater Res A 2009 Nov;91(2):519-27 PMID: 18985787 SCOPUS ID: 2-s2.0-70349445295 11/06/2008       35 Citations
  • Malignant solitary fibrous tumour of the meninges with marked amianthoid fibre deposition. (Lawlor MW, Nielsen GP, Louis DN) Neuropathol Appl Neurobiol 2008 Oct;34(5):569-72 PMID: 18298634 02/27/2008       7 Citations
  • Anti-neurofilament antibodies in neuropathy with monoclonal gammopathy of undetermined significance produce experimental motor nerve conduction block. (Stubbs EB Jr, Lawlor MW, Richards MP, Siddiqui K, Fisher MA, Bhoopalam N, Siegel GJ) Acta Neuropathol 2003 Feb;105(2):109-16 PMID: 12536221 01/22/2003       15 Citations
  • Antibodies to L-periaxin in sera of patients with peripheral neuropathy produce experimental sensory nerve conduction deficits. (Lawlor MW, Richards MP, De Vries GH, Fisher MA, Stubbs EB Jr) J Neurochem 2002 Nov;83(3):592-600 PMID: 12390521 10/23/2002       11 Citations
  • Sensory nerve conduction deficit in experimental monoclonal gammopathy of undetermined significance (MGUS) neuropathy. (Lawlor MW, Richards MP, Fisher MA, Stubbs EB Jr) Muscle Nerve 2001 Jun;24(6):809-16 PMID: 11360265 05/22/2001       8 Citations
  • Assessment of serum-mediated neurotoxicity in Navajo neuropathy. (Lawlor MW, Holve S, Stubbs EB Jr) Electromyogr Clin Neurophysiol 2000 Jun;40(4):211-4 PMID: 10907598 07/25/2000       4 Citations
  • Last update: 01/04/2021