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Publications indexed to the term Drug Evaluation, Preclinical

FacultyTitle
1Cardiotoxicity drug screening based on whole-panel intracellular recording. (Yang Y, Liu A, Tsai CT, Liu C, Wu JC, Cui B) Biosens Bioelectron 2022 Nov 15;216:114617       10 Citations
1Identification of novel modulators of a schistosome transient receptor potential channel targeted by praziquantel. (Chulkov EG, Smith E, Rohr CM, Yahya NA, Park SK, Scampavia L, Spicer TP, Marchant JS) PLoS Negl Trop Dis 2021 Nov;15(11):e0009898       11 Citations
3Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex I. (Zhang Q, Cheng G, Pan J, Zielonka J, Xiong D, Myers CR, Feng L, Shin SS, Kim YH, Bui D, Hu M, Bennett B, Schmainda K, Wang Y, Kalyanaraman B, You M) Cell Commun Signal 2020 Apr 07;18(1):58       24 Citations
1XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia. (Zook J, Shekhar M, Hansen D, Conrad C, Grant T, Gupta C, White T, Barty A, Basu S, Zhao Y, Zatsepin N, Ishchenko A, Batyuk A, Gati C, Li C, Galli L, Coe J, Hunter M, Liang M, Weierstall U, Nelson G, James D, Stauch B, Craciunescu F, Thifault D, Liu W, Cherezov V, Singharoy A, Fromme P) Structure 2020 May 05;28(5):540-547.e3       7 Citations
1Structure-based discovery of potent and selective melatonin receptor agonists. (Patel N, Huang XP, Grandner JM, Johansson LC, Stauch B, McCorvy JD, Liu Y, Roth B, Katritch V) Elife 2020 Mar 02;9       29 Citations
1Novel targeted therapies for the management of liver fibrosis. (Trivella JP, Martin P, Carrion AF) Expert Opin Emerg Drugs 2020 Mar;25(1):59-70       15 Citations
1Virtual discovery of melatonin receptor ligands to modulate circadian rhythms. (Stein RM, Kang HJ, McCorvy JD, Glatfelter GC, Jones AJ, Che T, Slocum S, Huang XP, Savych O, Moroz YS, Stauch B, Johansson LC, Cherezov V, Kenakin T, Irwin JJ, Shoichet BK, Roth BL, Dubocovich ML) Nature 2020 Mar;579(7800):609-614       212 Citations
1Preclinical Assessment with Clinical Validation of Selinexor with Gemcitabine and Nab-Paclitaxel for the Treatment of Pancreatic Ductal Adenocarcinoma. (Azmi AS, Khan HY, Muqbil I, Aboukameel A, Neggers JE, Daelemans D, Mahipal A, Dyson G, Kamgar M, Al-Hallak MN, Tesfaye A, Kim S, Shidham V, M Mohammad R, Philip PA) Clin Cancer Res 2020 Mar 15;26(6):1338-1348       40 Citations
1Statistical determination of synergy based on Bliss definition of drugs independence. (Demidenko E, Miller TW) PLoS One 2019;14(11):e0224137       89 Citations
1Pharmacological and biotransformation studies of 1-acyl-substituted derivatives of d-lysergic acid diethylamide (LSD). (Halberstadt AL, Chatha M, Klein AK, McCorvy JD, Meyer MR, Wagmann L, Stratford A, Brandt SD) Neuropharmacology 2020 Aug 01;172:107856       26 Citations
1Non-sedating benzodiazepines cause paralysis and tissue damage in the parasitic blood fluke Schistosoma mansoni. (McCusker P, Mian MY, Li G, Olp MD, Tiruveedhula VVNPB, Rashid F, Golani LK, Verma RS, Smith BC, Cook JM, Chan JD) PLoS Negl Trop Dis 2019 Nov;13(11):e0007826       4 Citations
4High-Throughput Screening of NOX Inhibitors. (Zielonka J, Zielonka M, Cheng G, Hardy M, Kalyanaraman B) Methods Mol Biol 2019;1982:429-446       12 Citations
1In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease. (Lin BL, Matera D, Doerner JF, Zheng N, Del Camino D, Mishra S, Bian H, Zeveleva S, Zhen X, Blair NT, Chong JA, Hessler DP, Bedja D, Zhu G, Muller GK, Ranek MJ, Pantages L, McFarland M, Netherton MR, Berry A, Wong D, Rast G, Qian HS, Weldon SM, Kuo JJ, Sauer A, Sarko C, Moran MM, Kass DA, Pullen SS) Proc Natl Acad Sci U S A 2019 May 14;116(20):10156-10161       102 Citations
1Developing zebrafish disease models for in vivo small molecule screens. (Lam PY, Peterson RT) Curr Opin Chem Biol 2019 Jun;50:37-44       63 Citations
2Studying Human Neurological Disorders Using Induced Pluripotent Stem Cells: From 2D Monolayer to 3D Organoid and Blood Brain Barrier Models. (Logan S, Arzua T, Canfield SG, Seminary ER, Sison SL, Ebert AD, Bai X) Compr Physiol 2019 Mar 14;9(2):565-611       96 Citations
1MIDD0301 - A first-in-class anti-inflammatory asthma drug targets GABAA receptors without causing systemic immune suppression. (Zahn NM, Huber AT, Mikulsky BN, Stepanski ME, Kehoe AS, Li G, Schussman M, Rashid Roni MS, Kodali R, Cook JM, Stafford DC, Steeber DA, Arnold LA) Basic Clin Pharmacol Toxicol 2019 Jul;125(1):75-84       11 Citations
1Inhibition of Cytomegalovirus Replication with Extended-Half-Life Synthetic Ozonides. (Wang Y, Mukhopadhyay R, Roy S, Kapoor A, Su YP, Charman SA, Chen G, Wu J, Wang X, Vennerstrom JL, Arav-Boger R) Antimicrob Agents Chemother 2019 Jan;63(1)       13 Citations
1Partial agonist activity of α1-adrenergic receptor antagonists for chemokine (C-X-C motif) receptor 4 and atypical chemokine receptor 3. (Gao X, Abdelkarim H, Albee LJ, Volkman BF, Gaponenko V, Majetschak M) PLoS One 2018;13(9):e0204041       6 Citations
1A screening campaign in sea urchin egg homogenate as a platform for discovering modulators of NAADP-dependent Ca2+ signaling in human cells. (Gunaratne GS, Johns ME, Hintz HM, Walseth TF, Marchant JS) Cell Calcium 2018 Nov;75:42-52       24 Citations
1Brain-Derived Neurotrophic Factor as a Treatment Option for Retinal Degeneration. (Daly C, Ward R, Reynolds AL, Galvin O, Collery RF, Kennedy BN) Adv Exp Med Biol 2018;1074:465-471       18 Citations
1Carbon monoxide and hydrogen sulphide reduce reperfusion injury in abdominal compartment syndrome. (Murphy PB, Bihari A, Parry NG, Ball I, Leslie K, Vogt K, Lawendy AR) J Surg Res 2018 Feb;222:17-25       2 Citations
1Serendipitous discovery of light-induced (In Situ) formation of an Azo-bridged dimeric sulfonated naphthol as a potent PTP1B inhibitor. (Bongard RD, Lepley M, Thakur K, Talipov MR, Nayak J, Lipinski RAJ, Bohl C, Sweeney N, Ramchandran R, Rathore R, Sem DS) BMC Biochem 2017 May 31;18(1):10       7 Citations
1Further evaluation of the potential anxiolytic activity of imidazo[1,5-a][1,4]diazepin agents selective for α2/3-containing GABAA receptors. (Witkin JM, Cerne R, Wakulchik M, S J, Gleason SD, Jones TM, Li G, Arnold LA, Li JX, Schkeryantz JM, Methuku KR, Cook JM, Poe MM) Pharmacol Biochem Behav 2017 Jun;157:35-40       23 Citations
1In silico design of novel probes for the atypical opioid receptor MRGPRX2. (Lansu K, Karpiak J, Liu J, Huang XP, McCorvy JD, Kroeze WK, Che T, Nagase H, Carroll FI, Jin J, Shoichet BK, Roth BL) Nat Chem Biol 2017 May;13(5):529-536       219 Citations
1Shape-based virtual screening, synthesis and evaluation of novel pyrrolone derivatives as antiviral agents against HCV. (Bassetto M, Leyssen P, Neyts J, Yerukhimovich MM, Frick DN, Brancale A) Bioorg Med Chem Lett 2017 Feb 15;27(4):936-940       13 Citations
15,6-δ-DHTL, a stable metabolite of arachidonic acid, is a potential EDHF that mediates microvascular dilation. (Levi-Rosenzvig R, Beyer AM, Hockenberry J, Ben-Shushan RS, Chuyun D, Atiya S, Tamir S, Gutterman DD, Szuchman-Sapir A) Free Radic Biol Med 2017 Feb;103:87-94       15 Citations
2Optimization of substituted imidazobenzodiazepines as novel asthma treatments. (Jahan R, Stephen MR, Forkuo GS, Kodali R, Guthrie ML, Nieman AN, Yuan NY, Zahn NM, Poe MM, Li G, Yu OB, Yocum GT, Emala CW, Stafford DC, Cook JM, Arnold LA) Eur J Med Chem 2017 Jan 27;126:550-560       18 Citations
2Radiation-induced changes in intestinal and tissue-nonspecific alkaline phosphatase: implications for recovery after radiation therapy. (Rentea RM, Lam V, Biesterveld B, Fredrich KM, Callison J, Fish BL, Baker JE, Komorowski R, Gourlay DM, Otterson MF) Am J Surg 2016 Oct;212(4):602-608       10 Citations
1Pharmacological profiling an abundantly expressed schistosome serotonergic GPCR identifies nuciferine as a potent antagonist. (Chan JD, Acharya S, Day TA, Marchant JS) Int J Parasitol Drugs Drug Resist 2016 Dec;6(3):364-370       22 Citations
1Kinetic profiling an abundantly expressed planarian serotonergic GPCR identifies bromocriptine as a perdurant antagonist. (Chan JD, Grab T, Marchant JS) Int J Parasitol Drugs Drug Resist 2016 Dec;6(3):356-363       16 Citations
2A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors. (Chan JD, McCorvy JD, Acharya S, Johns ME, Day TA, Roth BL, Marchant JS) PLoS Pathog 2016 May;12(5):e1005651       30 Citations
1Experimental Models of Anxiety for Drug Discovery and Brain Research. (Hart PC, Bergner CL, Smolinsky AN, Dufour BD, Egan RJ, LaPorte JL, Kalueff AV) Methods Mol Biol 2016;1438:271-91       17 Citations
1Bruton tyrosine kinase inhibition in chronic lymphocytic leukemia. (Maddocks K, Jones JA) Semin Oncol 2016 Apr;43(2):251-9       26 Citations
1Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models. (Cheng J, Giguere PM, Schmerberg CM, Pogorelov VM, Rodriguiz RM, Huang XP, Zhu H, McCorvy JD, Wetsel WC, Roth BL, Kozikowski AP) J Med Chem 2016 Jan 28;59(2):578-91       23 Citations
2Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production. (Guo Y, Fan Y, Zhang J, Lomberk GA, Zhou Z, Sun L, Mathison AJ, Garcia-Barrio MT, Zhang J, Zeng L, Li L, Pennathur S, Willer CJ, Rader DJ, Urrutia R, Chen YE) J Clin Invest 2015 Oct 01;125(10):3819-30       66 Citations
1Identification of inhibitors that target dual-specificity phosphatase 5 provide new insights into the binding requirements for the two phosphate pockets. (Neumann TS, Span EA, Kalous KS, Bongard R, Gastonguay A, Lepley MA, Kutty RG, Nayak J, Bohl C, Lange RG, Sarker MI, Talipov MR, Rathore R, Ramchandran R, Sem DS) BMC Biochem 2015 Aug 19;16:19       8 Citations
1Clarithromycin enhances the antimalarial efficacy of mefloquine via its increased bioavailability and disrupting P. falciparum apicoplast. (Gunjan S, Singh SK, Chauhan BS, Pandey SK, Ahmad H, Dwivedi AK, Tripathi R) Life Sci 2015 Sep 01;136:126-32       3 Citations
1Targeting epidermal fatty acid binding protein for treatment of experimental autoimmune encephalomyelitis. (Rao E, Singh P, Li Y, Zhang Y, Chi YI, Suttles J, Li B) BMC Immunol 2015 May 12;16:28       29 Citations
1Discovery of bisamide-heterocycles as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake. (Dockendorff C, Faloon PW, Germain A, Yu M, Youngsaye W, Nag PP, Bennion M, Penman M, Nieland TJ, Dandapani S, Perez JR, Munoz B, Palmer MA, Schreiber SL, Krieger M) Bioorg Med Chem Lett 2015 Jun 15;25(12):2594-8       11 Citations
2Intestinal alkaline phosphatase to treat necrotizing enterocolitis. (Biesterveld BE, Koehler SM, Heinzerling NP, Rentea RM, Fredrich K, Welak SR, Gourlay DM) J Surg Res 2015 Jun 15;196(2):235-40       17 Citations
1Synthesis and pharmacological evaluation of N-benzyl substituted 4-bromo-2,5-dimethoxyphenethylamines as 5-HT2A/2C partial agonists. (Hansen M, Jacobsen SE, Plunkett S, Liebscher GE, McCorvy JD, Bräuner-Osborne H, Kristensen JL) Bioorg Med Chem 2015 Jul 15;23(14):3933-7       23 Citations
1Ibrutinib treatment ameliorates murine chronic graft-versus-host disease. (Dubovsky JA, Flynn R, Du J, Harrington BK, Zhong Y, Kaffenberger B, Yang C, Towns WH, Lehman A, Johnson AJ, Muthusamy N, Devine SM, Jaglowski S, Serody JS, Murphy WJ, Munn DH, Luznik L, Hill GR, Wong HK, MacDonald KK, Maillard I, Koreth J, Elias L, Cutler C, Soiffer RJ, Antin JH, Ritz J, Panoskaltsis-Mortari A, Byrd JC, Blazar BR) J Clin Invest 2014 Nov;124(11):4867-76       160 Citations
1Clodronate exerts an anabolic effect on articular chondrocytes mediated through the purinergic receptor pathway. (Rosa RG, Collavino K, Lakhani A, Delve E, Weber JF, Rosenthal AK, Waldman SD) Osteoarthritis Cartilage 2014 Sep;22(9):1327-36       22 Citations
1Protective effect of administration of Withania somifera against bromobenzene induced nephrotoxicity and mitochondrial oxidative stress in rats. (Vedi M, Rasool M, Sabina EP) Ren Fail 2014 Aug;36(7):1095-103       14 Citations
1Zebrafish heart failure models for the evaluation of chemical probes and drugs. (Huang CC, Monte A, Cook JM, Kabir MS, Peterson KP) Assay Drug Dev Technol 2013;11(9-10):561-72       43 Citations
1Exploiting pluripotent stem cell technology for drug discovery, screening, safety, and toxicology assessments. (McGivern JV, Ebert AD) Adv Drug Deliv Rev 2014 Apr;69-70:170-8       23 Citations
1Intrahypothalamic pituitary adenylate cyclase-activating polypeptide regulates energy balance via site-specific actions on feeding and metabolism. (Resch JM, Maunze B, Gerhardt AK, Magnuson SK, Phillips KA, Choi S) Am J Physiol Endocrinol Metab 2013 Dec;305(12):E1452-63       52 Citations
1Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease. (Zhou X, Fan LX, Sweeney WE Jr, Denu JM, Avner ED, Li X) J Clin Invest 2013 Jul;123(7):3084-98       133 Citations
1Effects of combination therapy with dipeptidyl peptidase-IV and histone deacetylase inhibitors in the non-obese diabetic mouse model of type 1 diabetes. (Cabrera SM, Colvin SC, Tersey SA, Maier B, Nadler JL, Mirmira RG) Clin Exp Immunol 2013 Jun;172(3):375-82       32 Citations
1Delayed post-injury administration of riluzole is neuroprotective in a preclinical rodent model of cervical spinal cord injury. (Wu Y, Satkunendrarajah K, Teng Y, Chow DS, Buttigieg J, Fehlings MG) J Neurotrauma 2013 Mar 15;30(6):441-52       79 Citations
1High-throughput identification of promiscuous inhibitors from screening libraries with the use of a thiol-containing fluorescent probe. (McCallum MM, Nandhikonda P, Temmer JJ, Eyermann C, Simeonov A, Jadhav A, Yasgar A, Maloney D, Arnold AL) J Biomol Screen 2013 Jul;18(6):705-13       24 Citations
1Evaluation of adamantane hydroxamates as botulinum neurotoxin inhibitors: synthesis, crystallography, modeling, kinetic and cellular based studies. (Šilhár P, Silvaggi NR, Pellett S, Čapková K, Johnson EA, Allen KN, Janda KD) Bioorg Med Chem 2013 Mar 01;21(5):1344-8       50 Citations
1On scaffold hopping: challenges in the discovery of sulfated small molecules as mimetics of glycosaminoglycans. (Sidhu PS, Mosier PD, Zhou Q, Desai UR) Bioorg Med Chem Lett 2013 Jan 01;23(1):355-9       13 Citations
1Disruption of fatty acid amide hydrolase activity prevents the effects of chronic stress on anxiety and amygdalar microstructure. (Hill MN, Kumar SA, Filipski SB, Iverson M, Stuhr KL, Keith JM, Cravatt BF, Hillard CJ, Chattarji S, McEwen BS) Mol Psychiatry 2013 Oct;18(10):1125-35       187 Citations
1Electrocardiograms (ECGs) in phase I anticancer drug development: the MD Anderson Cancer Center experience with 8518 ECGs. (Naing A, Veasey-Rodrigues H, Hong DS, Fu S, Falchook GS, Wheler JJ, Tsimberidou AM, Wen S, Fessahaye SN, Golden EC, Aaron J, Ewer MS, Kurzrock R) Ann Oncol 2012 Nov;23(11):2960-2963       39 Citations
4Intestinal alkaline phosphatase administration in newborns is protective of gut barrier function in a neonatal necrotizing enterocolitis rat model. (Rentea RM, Liedel JL, Welak SR, Cassidy LD, Mayer AN, Pritchard KA Jr, Oldham KT, Gourlay DM) J Pediatr Surg 2012 Jun;47(6):1135-42       49 Citations
4Intestinal alkaline phosphatase administration in newborns decreases systemic inflammatory cytokine expression in a neonatal necrotizing enterocolitis rat model. (Rentea RM, Liedel JL, Fredrich K, Welak SR, Pritchard KA Jr, Oldham KT, Simpson PM, Gourlay DM) J Surg Res 2012 Oct;177(2):228-34       14 Citations
1Aerosolized 3-bromopyruvate inhibits lung tumorigenesis without causing liver toxicity. (Zhang Q, Pan J, North PE, Yang S, Lubet RA, Wang Y, You M) Cancer Prev Res (Phila) 2012 May;5(5):717-25       35 Citations
1Effect of Thuja occidentalis and its polysaccharide on cell-mediated immune responses and cytokine levels of metastatic tumor-bearing animals. (Sunila ES, Hamsa TP, Kuttan G) Pharm Biol 2011 Oct;49(10):1065-73       31 Citations
1A quantitative high-throughput screen identifies novel inhibitors of the interaction of thyroid receptor beta with a peptide of steroid receptor coactivator 2. (Johnson RL, Hwang JY, Arnold LA, Huang R, Wichterman J, Augustinaite I, Austin CP, Inglese J, Guy RK, Huang W) J Biomol Screen 2011 Jul;16(6):618-27       14 Citations
1Nilotinib cardiac toxicity: should we still be concerned? (Atallah E) Leuk Res 2011 May;35(5):577-8       10 Citations
1Recombinant luciferase-expressing human cytomegalovirus (CMV) for evaluation of CMV inhibitors. (He R, Sandford G, Hayward GS, Burns WH, Posner GH, Forman M, Arav-Boger R) Virol J 2011 Jan 26;8:40       35 Citations
1Crossroads of pain and addiction. (Bailey JA, Hurley RW, Gold MS) Pain Med 2010 Dec;11(12):1803-18       37 Citations
2Neuroprotection by a mitochondria-targeted drug in a Parkinson's disease model. (Ghosh A, Chandran K, Kalivendi SV, Joseph J, Antholine WE, Hillard CJ, Kanthasamy A, Kanthasamy A, Kalyanaraman B) Free Radic Biol Med 2010 Dec 01;49(11):1674-84       171 Citations
1Pterostilbene inhibits pancreatic cancer in vitro. (Mannal PW, Alosi JA, Schneider JG, McDonald DE, McFadden DW) J Gastrointest Surg 2010 May;14(5):873-9       53 Citations
1Pterostilbene inhibits lung cancer through induction of apoptosis. (Schneider JG, Alosi JA, McDonald DE, McFadden DW) J Surg Res 2010 Jun 01;161(1):18-22       67 Citations
1Experimental models of anxiety for drug discovery and brain research. (Hart PC, Bergner CL, Smolinsky AN, Dufour BD, Egan RJ, Laporte JL, Kalueff AV) Methods Mol Biol 2010;602:299-321       45 Citations
1The therapeutic potential of the endocannabinoid system for the development of a novel class of antidepressants. (Hill MN, Hillard CJ, Bambico FR, Patel S, Gorzalka BB, Gobbi G) Trends Pharmacol Sci 2009 Sep;30(9):484-93       150 Citations
1Consensus recommendations to accelerate clinical trials for neurofibromatosis type 2. (Evans DG, Kalamarides M, Hunter-Schaedle K, Blakeley J, Allen J, Babovic-Vuskanovic D, Belzberg A, Bollag G, Chen R, DiTomaso E, Golfinos J, Harris G, Jacob A, Kalpana G, Karajannis M, Korf B, Kurzrock R, Law M, McClatchey A, Packer R, Roehm P, Rubenstein A, Slattery W 3rd, Tonsgard JH, Welling DB, Widemann B, Yohay K, Giovannini M) Clin Cancer Res 2009 Aug 15;15(16):5032-5039       66 Citations
1Fumarates: unique nondepolarizing neuromuscular blocking agents that are antagonized by cysteine. (Lien CA, Savard P, Belmont M, Sunaga H, Savarese JJ) J Crit Care 2009 Mar;24(1):50-7       24 Citations
1Novel dual-reporter preclinical screen for antiastrocytoma agents identifies cytostatic and cytotoxic compounds. (Hawes JJ, Nerva JD, Reilly KM) J Biomol Screen 2008 Sep;13(8):795-803       10 Citations
1Topical interleukin-1 receptor antagonist inhibits inflammatory cell infiltration into the cornea. (Stapleton WM, Chaurasia SS, Medeiros FW, Mohan RR, Sinha S, Wilson SE) Exp Eye Res 2008 May;86(5):753-7       51 Citations
1Iclaprim, a diaminopyrimidine dihydrofolate reductase inhibitor for the potential treatment of antibiotic-resistant staphylococcal infections. (Peppard WJ, Schuenke CD) Curr Opin Investig Drugs 2008 Feb;9(2):210-25       36 Citations
1Identification of antidepressant drug leads through the evaluation of marine natural products with neuropsychiatric pharmacophores. (Diers JA, Ivey KD, El-Alfy A, Shaikh J, Wang J, Kochanowska AJ, Stoker JF, Hamann MT, Matsumoto RR) Pharmacol Biochem Behav 2008 Mar;89(1):46-53       29 Citations
1Synthesis of highly substituted dibenzo[b,f]azocines and their evaluation as protein kinase inhibitors. (Arnold LA, Kiplin Guy R) Bioorg Med Chem Lett 2006 Oct 15;16(20):5360-3       18 Citations
1A high-throughput screening method to identify small molecule inhibitors of thyroid hormone receptor coactivator binding. (Arnold LA, Estébanez-Perpiñá E, Togashi M, Shelat A, Ocasio CA, McReynolds AC, Nguyen P, Baxter JD, Fletterick RJ, Webb P, Guy RK) Sci STKE 2006 Jun 27;2006(341):pl3       29 Citations
1Pharmacological evaluation of cannabinoid receptor ligands in a mouse model of anxiety: further evidence for an anxiolytic role for endogenous cannabinoid signaling. (Patel S, Hillard CJ) J Pharmacol Exp Ther 2006 Jul;318(1):304-11       344 Citations
1Strategies for delaying or treating in vivo acquired resistance to trastuzumab in human breast cancer xenografts. (du Manoir JM, Francia G, Man S, Mossoba M, Medin JA, Viloria-Petit A, Hicklin DJ, Emmenegger U, Kerbel RS) Clin Cancer Res 2006 Feb 01;12(3 Pt 1):904-16       128 Citations
1A murine model of deep vein thrombosis: characterization and validation in transgenic mice. (Cooley BC, Szema L, Chen CY, Schwab JP, Schmeling G) Thromb Haemost 2005 Sep;94(3):498-503       39 Citations
1Synthesis and pharmacological screening for muscle relaxant, anticonvulsant, and sedative activities of certain organic compounds produced by Michael addition. (Said MM, Ahmed AA, El-Alfy AT) Arch Pharm Res 2004 Dec;27(12):1194-201       6 Citations
1Comparison of hyperkalemic cardioplegia with altered [CaCl2] and [MgCl2] on [Ca2+]i transients and function after warm global ischemia in isolated hearts. (Camara AK, Chen Q, An J, Novalija E, Riess ML, Rhodes SS, Stowe DF) J Cardiovasc Surg (Torino) 2004 Feb;45(1):1-13       9 Citations
1Recombinant factor IX. (White GC 2nd, Beebe A, Nielsen B) Thromb Haemost 1997 Jul;78(1):261-5       188 Citations
1Modulation of in vitro and in vivo T-cell responses by transferrin-gallium and gallium nitrate. (Drobyski WR, Ul-Haq R, Majewski D, Chitambar CR) Blood 1996 Oct 15;88(8):3056-64       26 Citations
1Pharmacological management of spinal cord injury: current status of drugs designed to augment functional recovery of the injured human spinal cord. (Greene KA, Marciano FF, Sonntag VK) J Spinal Disord 1996 Oct;9(5):355-66       15 Citations
1[Effect of indomethacin on the development of periodontitis in relatively gnotobiotic rats]. (Hefti A, Erhardt A) Schweiz Monatsschr Zahnmed (1984) 1985 Jan;95(1):71-6