Mesh term Genes, Tumor Suppressor
Browse to parent terms:Genes, Neoplasm
Genes, Recessive
Description
Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.Browse to child terms:
Genes, APC
Genes, BRCA1
Genes, BRCA2
Genes, DCC
Genes, MCC
Genes, Neurofibromatosis 1
Genes, Neurofibromatosis 2
Genes, Retinoblastoma
Genes, Wilms Tumor
Genes, p16
Genes, p53
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