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Mesh term Zinc Fingers

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Amino Acid Motifs


Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites.

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CYS2-HIS2 Zinc Fingers
MYND Domains
PHD Zinc Fingers
RING Finger Domains

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