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Mesh term Receptors, Somatomedin

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Receptors, Growth Factor

Description

Cell surface receptors that bind somatomedins and trigger intracellular changes which influence the behavior of cells. Studies have disclosed two types of receptors for this family of peptide hormones. The type I receptor is homologous to the insulin receptor and has tyrosine kinase activity. The type II receptor is identical to the mannose-6-phosphate receptor which is important in trafficking of lysosomal enzymes.


Browse to child terms:
Receptor, IGF Type 1
Receptor, IGF Type 2


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jenkins-FCD Prod-486 e3098984f26de787f5ecab75090d0a28e7f4f7c0