Mesh term Integrin alpha Chains
Browse to parent terms:Integrins
Description
The alpha subunits of integrin heterodimers (INTEGRINS), which mediate ligand specificity. There are approximately 18 different alpha chains, exhibiting great sequence diversity; several chains are also spliced into alternative isoforms. They possess a long extracellular portion (1200 amino acids) containing a MIDAS (metal ion-dependent adhesion site) motif, and seven 60-amino acid tandem repeats, the last 4 of which form EF HAND MOTIFS. The intracellular portion is short with the exception of INTEGRIN ALPHA4.Browse to child terms:
CD11a Antigen
CD11b Antigen
CD11c Antigen
Integrin alpha1
Integrin alpha2
Integrin alpha3
Integrin alpha4
Integrin alpha5
Integrin alpha6
Integrin alphaV
Platelet Membrane Glycoprotein IIb
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