Molecular and cellular basis of congenital heart disease. Pediatr Clin North Am 2006 Oct;53(5):989-1009, x
Date
10/10/2006Pubmed ID
17027620DOI
10.1016/j.pcl.2006.08.010Scopus ID
2-s2.0-33749431116 (requires institutional sign-in at Scopus site) 18 CitationsAbstract
The cellular and molecular basis of congenital heart disease (CHD) is an evolving area of rapid discovery. This article introduced the basic mechanisms underlying cardiac development and CHD in order to permit a clear understanding of current diagnostics and therapeutics and their future development. It is clear that although significant advances have been made in understanding mechanisms controlling heart formation, the direct causes of CHD remain poorly defined. Future studies tha delineate the complexity of these mechanisms are required to provide a comprehensive understanding of the etiologies of CHD. Such understanding will lead to the development of novel approaches to prevention and therapy.
Author List
Sander TL, Klinkner DB, Tomita-Mitchell A, Mitchell MEAuthors
Michael Edward Mitchell MD Chief, Professor in the Surgery department at Medical College of WisconsinAoy Tomita Mitchell PhD Professor in the Surgery department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
AnimalsDisease Progression
Heart
Heart Defects, Congenital
Humans
Infant, Newborn
Molecular Biology
Risk Factors
