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Michael Edward Mitchell MD

Michael Edward Mitchell MD profile photo picture

Professor

Institution: Medical College of Wisconsin
Department: Surgery
Division: Pediatric Congenital Cardiac Surgery
Program: Pediatrics

Member of the Cardiovascular Center
Member of the Genomic Sciences and Precision Medicine Center (GSPMC)


I am willing to mentor a junior faculty member.
I am willing to collaborate on research projects.


Research Experience

  • Bioengineered Heart Cells in Hypoplastic Left Heart Syndrome (HLHS)
  • Highly Sensitive, Non-Invasive Cardiac Transplant Rejection
  • Total Cell-Free Deoxyribonucleic Acid (total of cf-DNA) Predictor
  • Genetic Impact of MYH6 Variants
  • Clinical Expertise

  • Cardiovascular Surgery
  • Heart, Lung and Heart/Lung Transplantation
  • Neonatal and Infant Cardiac Surgery
  • Valve Reconstruction
  • Tracheal Suspension
  • Adult Congenital Cardiac Surgery
  • Leadership Positions

  • Co-Chair Children's Specialty Group (CSG) Quality Committee
  • Board Member, Children's Specialty Group (CSG)
  • Member, Congenital Heart Surgeons' Society (CHS), Standards & Ethics Committee
  • Member, Thoracic Surgery Directors Association (TSDA) Congenital Cardiac Fellowship Committee
  • Director, Children's Hospital of Wisconsin (CHW) Tracheal Reconstruction Team
  • Member, National Institutes of Health (NIH) Pediatric Mechanical Support Device Committee
  • Board Member, United Network for Organ Sharing, Region 7 Regional Heart Review
  • Member, American College of Cardiology (ACC), Section Leadership Council
  • Course Chair, American Association for Thoracic Surgery (AATS)/Society of Thoracic Surgeons (STS) Congenital Heart Disease Symposium
  • Member, Congenital Heart Surgeons' Society (CHS), Standards & Ethics Committee
  • Member & Scientific Reviewer, US Dept. of Defense, Medical Research Program (PRMRP)
  • Reviewer, American Heart Association (AHA), Cardiovascular Development CL
  • Member, Children's Specialty Group (CSG) Finance Committee
  • Chair Person, American College of Cardiology (ACC), Congenital Program Committee
  • Member & Scientific Reviewer, US Dept. of Defense, Pre-Congenital Heart Disease (Pre-CHD)
  • Member & Scientific Reviewer, US Dept. of Defense, Congressionally Directed Medical Research Programs (CDMRP)
  • MCW Program / Core Facilities

  • Advisory Committee, Pediatric Cardiology Research Fellow
  • Course Director, Pediatric Cardiothoracic Surgery Rotation
  • Member, Cardiovascular Scientific Advisory Committee
  • Course Director, Pediatric Cardiothoracic Surgery, Integrative Selective for Fourth Year Medical Sutdents
  • Member, DiGeorge Program Planning Committee
  • ACGME Accredited Residency Pediatric Cardiothoracic Surgical Training Program
  • Program Director, ACGME Fellowship in Pediatric Cardiothoracic Surgery
  • Member, Immunodeficiency Subcommittee
  • Educational Expertise

  • 1995 M.D. Harvard Medical School (Magna Cum Laude)
  • 1990 A.B. Princeton University, Chemistry (Cum Laude)
  • 2017 Harvard T.H. Chan School of Public Health, Leadership Development for Physicians in Academic Health Centers
  • Community Partnerships

  • Member, WI Statewide Umbrella Immunodeficiency Newborn Screening Subcomittee
  • Publications (115)

  • Nitric oxide added to the sweep gas of the oxygenator during cardiopulmonary bypass in infants: A pilot randomized controlled trial. (Niebler RA, Chiang-Ching H, Daley K, Janecke R, Jobe SM, Mitchell ME, Varner C, Woods K, Scott JP) Artif Organs 2020 Aug 01 PMID: 32737900 SCOPUS ID: 2-s2.0-85090452040 08/02/2020    
  • Contractility of Induced Pluripotent Stem Cell-Cardiomyocytes With an MYH6 Head Domain Variant Associated With Hypoplastic Left Heart Syndrome. (Kim MS, Fleres B, Lovett J, Anfinson M, Samudrala SSK, Kelly LJ, Teigen LE, Cavanaugh M, Marquez M, Geurts AM, Lough JW, Mitchell ME, Fitts RH, Tomita-Mitchell A) Front Cell Dev Biol 2020;8:440 PMID: 32656206 PMCID: PMC7324479 07/14/2020    
  • Interventions Associated with Treatment of Low Cardiac Output following Stage 1 Norwood Palliation. (Hoffman GM, Niebler RA, Scott JP, Bertrandt RA, Wakeham MK, Thompson NE, Ghanayem NS, Stuth EA, Mitchell ME, Woods RK, Hraska V, Mussatto KA, Tweddell JS) Ann Thorac Surg 2020 Jul 08 PMID: 32652068 07/12/2020    
  • Commentary: Plastic Valves Calcify Too? (Mitchell ME) Semin Thorac Cardiovasc Surg 2020 Jun 28 PMID: 32610194 SCOPUS ID: 2-s2.0-85088982595 07/02/2020    
  • Commentary: A long haul and a short slide? (Mitchell ME) J Thorac Cardiovasc Surg 2020 09;160(3):807-808 PMID: 32605733 SCOPUS ID: 2-s2.0-85087010269 07/02/2020    
  • Contractility of Induced Pluripotent Stem Cell-Cardiomyocytes With an MYH6 Head Domain Variant Associated With Hypoplastic Left Heart Syndrome (Kim MS, Fleres B, Lovett J, Anfinson M, Samudrala SSK, Kelly LJ, Teigen LE, Cavanaugh M, Marquez M, Geurts AM, Lough JW, Mitchell ME, Fitts RH, Tomita-Mitchell A) Frontiers in Cell and Developmental Biology 23 June 2020;8 SCOPUS ID: 2-s2.0-85087475806 06/23/2020    
  • Innominate Vein Turn-down Procedure for Failing Fontan Circulation. (Hraska V, Mitchell ME, Woods RK, Hoffman GM, Kindel SJ, Ginde S) Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2020;23:34-40 PMID: 32354545 05/02/2020    
  • Natural History of Hemodynamic Maturation Post Heart Transplantation in the Absence of Rejection (Deshpande SR, Simpson PM, Zhang L, -Mitchell AT, Mitchell ME) The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 1 April 2020;39(4):S463 PMID: 32465812 SCOPUS ID: 2-s2.0-85085588699 04/01/2020    
  • Novel KLHL26 variant associated with a familial case of Ebstein's anomaly and left ventricular noncompaction. (Samudrala SSK, North LM, Stamm KD, Earing MG, Frommelt MA, Willes R, Tripathi S, Dsouza NR, Zimmermann MT, Mahnke DK, Liang HL, Lund M, Lin CW, Geddes GC, Mitchell ME, Tomita-Mitchell A) Mol Genet Genomic Med 2020 04;8(4):e1152 PMID: 31985165 PMCID: PMC7196453 SCOPUS ID: 2-s2.0-85078673520 01/28/2020    
  • Donor fraction cell-free DNA and rejection in adult and pediatric heart transplantation. (Richmond ME, Zangwill SD, Kindel SJ, Deshpande SR, Schroder JN, Bichell DP, Knecht KR, Mahle WT, Wigger MA, Gaglianello NA, Pahl E, Simpson PM, Dasgupta M, North PE, Hidestrand M, Tomita-Mitchell A, Mitchell ME) J Heart Lung Transplant 2020 May;39(5):454-463 PMID: 31983667 SCOPUS ID: 2-s2.0-85078178592 01/28/2020       2 Citations
  • Commentary: No justification for transplantation in place of standard surgical palliation. (Mitchell ME) J Thorac Cardiovasc Surg 2020 04;159(4):1463-1465 PMID: 31982131 SCOPUS ID: 2-s2.0-85078179123 01/27/2020    
  • Mitral Valve Surgery in Neonates, Infants, and Children: Surgical Approach, Outcomes, and Predictors. (Isaacson E, Lucjak C, Johnson WK, Yin Z, Wang T, Rein L, Woods RK, Tweddell JS, Hraska V, Mitchell ME) Semin Thorac Cardiovasc Surg 2020 Autumn;32(3):541-550 PMID: 31972302 SCOPUS ID: 2-s2.0-85079867076 01/24/2020       1 Citation
  • Cell-free DNA donor fraction analysis in pediatric and adult heart transplant patients by multiplexed allele-specific quantitative PCR: Validation of a rapid and highly sensitive clinical test for stratification of rejection probability. (North PE, Ziegler E, Mahnke DK, Stamm KD, Thomm A, Daft P, Goetsch M, Liang HL, Baker MA, Vepraskas A, Rosenau C, Dasgupta M, Simpson P, Mitchell ME, Tomita-Mitchell A) PLoS One 2020;15(1):e0227385 PMID: 31929557 PMCID: PMC6957190 SCOPUS ID: 2-s2.0-85077765307 01/14/2020       1 Citation
  • Innominate Vein Turn-down Procedure for Failing Fontan Circulation (Hraska V, Mitchell ME, Woods RK, Hoffman GM, Kindel SJ, Ginde S) Seminars in Thoracic and Cardiovascular Surgery: Pediatric Cardiac Surgery Annual 2020 SCOPUS ID: 2-s2.0-85080101619 01/01/2020    
  • Commentary: A long haul and a short slide? (Mitchell ME) Journal of Thoracic and Cardiovascular Surgery 2020 SCOPUS ID: 2-s2.0-85087010269 01/01/2020    
  • Safety and Efficacy of Vasopressin After Fontan Completion: A Randomized Pilot Study. (Bigelow AM, Ghanayem NS, Thompson NE, Scott JP, Cassidy LD, Woods KJ, Woods RK, Mitchell ME, Hraŝka V, Hoffman GM) Ann Thorac Surg 2019 12;108(6):1865-1874 PMID: 31400337 SCOPUS ID: 2-s2.0-85074440821 08/11/2019       2 Citations
  • Proximal Arch in Left Thoracotomy Repair of Neonatal and Infant Coarctation-How Small Is Too Small? (Callahan CP, Saudek D, Creighton S, Kuhn EM, Mitchell ME, Tweddell JS, Woods RK) World J Pediatr Congenit Heart Surg 2019 07;10(4):469-474 PMID: 31307310 07/17/2019    
  • Waiting for Weight - 2.0 Is the New 2.5. (Mitchell ME) Semin Thorac Cardiovasc Surg 2019;31(3):494-495 PMID: 31071443 SCOPUS ID: 2-s2.0-85065919507 05/10/2019    
  • Human genotyping and an experimental model reveal NPR-C as a possible contributor to morbidity in coarctation of the aorta. (LaDisa JF Jr, Tomita-Mitchell A, Stamm K, Bazan K, Mahnke DK, Goetsch MA, Wegter BJ, Gerringer JW, Repp K, Palygin O, Zietara AP, Krolikowski MM, Eddinger TJ, Alli AA, Mitchell ME) Physiol Genomics 2019 06 01;51(6):177-185 PMID: 31002586 PMCID: PMC6620646 SCOPUS ID: 2-s2.0-85066457176 04/20/2019       2 Citations
  • Variation in the use of Fontan fenestration in the current surgical era (Hill GD, Ghanayem NS, Hraska V, Jacobsen RM, Mitchell ME, Woods RK, Ginde S) Progress in Pediatric Cardiology March 2019;52:4-7 SCOPUS ID: 2-s2.0-85052741587 03/01/2019    
  • Metakaryotic cells linked to pediatric pulmonary vein stenosis. (Kirkpatrick EC, Mitchell ME, Thilly WG, Hidestrand P, Tomita-Mitchell A, Hidestrand M, Gostjeva EV) Cardiovasc Pathol 2019 Mar - Apr;39:51-53 PMID: 30660022 SCOPUS ID: 2-s2.0-85059952993 01/20/2019    
  • Coronary ostial aneurysms following aortic root replacement in patients with familial aortic aneurysm are common and support the need for long-term surveillance (Krishna H, Ginde S, Katzmark L, Mitchell M, Woods R, Hraska V, Earing MG) Progress in Pediatric Cardiology 2019 SCOPUS ID: 2-s2.0-85065233771 01/01/2019    
  • Monocusp valve placement in children with tetralogy of Fallot undergoing repair with transannular patch: A functioning pulmonary valve does not improve immediate postsurgical outcomes. (Singh NM, Loomba RS, Gudausky TM, Mitchell ME) Congenit Heart Dis 2018 Nov;13(6):935-943 PMID: 30260077 SCOPUS ID: 2-s2.0-85053930987 09/28/2018       1 Citation
  • Porcine Small Intestinal Submucosa May Be a Suitable Material for Norwood Arch Reconstruction. (Jacobsen RM, Mitchell ME, Woods RK, Loomba RS, Tweddell JS) Ann Thorac Surg 2018 12;106(6):1847-1852 PMID: 30055141 SCOPUS ID: 2-s2.0-85054784003 07/29/2018       5 Citations
  • Noninvasive Assay for Donor Fraction of Cell-Free DNA in Pediatric Heart Transplant Recipients. (Ragalie WS, Stamm K, Mahnke D, Liang HL, Simpson P, Katz R, Tomita-Mitchell A, Kindel SJ, Zangwill S, Mitchell ME) J Am Coll Cardiol 2018 06 26;71(25):2982-2983 PMID: 29929623 SCOPUS ID: 2-s2.0-85048264947 06/23/2018       7 Citations
  • 360-Degree Cone Reconstruction for Ebstein's Anomaly. (Mitchell ME, Hraska V, Kouretas PC) Ann Thorac Surg 2018 09;106(3):e155-e158 PMID: 29730350 SCOPUS ID: 2-s2.0-85051675303 05/08/2018       1 Citation
  • Single center experience with the Potts shunt in severe pulmonary arterial hypertension (Kirkpatrick EC, Handler SS, Foerster S, Gudausky T, Tillman K, Mitchell M) Progress in Pediatric Cardiology March 2018;48:111-115 SCOPUS ID: 2-s2.0-85039698817 03/01/2018    
  • Introduction. (Mitchell ME) Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2018 Mar;21:1 PMID: 29425518 02/10/2018    
  • Total Artificial Heart Using Bilateral Paracorporeal Pulsatile Ventricular Assist Devices in an 8.2-kg Child. (Woods RK, Kindel SJ, Mitchell ME, Hraska V, Niebler RA) Ann Thorac Surg 2018 06;105(6):e255-e257 PMID: 29371040 SCOPUS ID: 2-s2.0-85047127070 01/27/2018       1 Citation
  • Multiple mechanical support modalities and cardiac transplantation in a young child with corrected transposition. (Woods RK, Neibler RA, Kindel SJ, Mitchell ME, Tweddell JS, Hraska V) J Thorac Cardiovasc Surg 2018 05;155(5):e161-e163 PMID: 29331178 SCOPUS ID: 2-s2.0-85040442829 01/15/2018       1 Citation
  • Vascular rings and pulmonary artery sling (Ragalie WS, Mitchell ME) Critical Heart Disease in Infants and Children 1 January 2018:544-550.e1 SCOPUS ID: 2-s2.0-85082266858 01/01/2018    
  • Surgical unroofing of intramural anomalous aortic origin of a coronary artery in pediatric patients: Single-center perspective. (Sachdeva S, Frommelt MA, Mitchell ME, Tweddell JS, Frommelt PC) J Thorac Cardiovasc Surg 2018 04;155(4):1760-1768 PMID: 29246546 SCOPUS ID: 2-s2.0-85037732553 12/17/2017       9 Citations
  • Infectious complications of ventricular assist device use in children in the United States: Data from the Pediatric Interagency Registry for Mechanical Circulatory Support (Pedimacs). (Auerbach SR, Richmond ME, Schumacher KR, Lopez-Colon D, Mitchell MB, Turrentine MW, Cantor RS, Niebler RA, Eghtesady P) J Heart Lung Transplant 2018 01;37(1):46-53 PMID: 29107545 PMCID: PMC5849428 SCOPUS ID: 2-s2.0-85032300815 11/07/2017       5 Citations
  • Genome-Wide Association Study to Find Modifiers for Tetralogy of Fallot in the 22q11.2 Deletion Syndrome Identifies Variants in the GPR98 Locus on 5q14.3. (Guo T, Repetto GM, McDonald McGinn DM, Chung JH, Nomaru H, Campbell CL, Blonska A, Bassett AS, Chow EWC, Mlynarski EE, Swillen A, Vermeesch J, Devriendt K, Gothelf D, Carmel M, Michaelovsky E, Schneider M, Eliez S, Antonarakis SE, Coleman K, Tomita-Mitchell A, Mitchell ME, Digilio MC, Dallapiccola B, Marino B, Philip N, Busa T, Kushan-Wells L, Bearden CE, Piotrowicz M, Hawuła W, Roberts AE, Tassone F, Simon TJ, van Duin EDA, van Amelsvoort TA, Kates WR, Zackai E, Johnston HR, Cutler DJ, Agopian AJ, Goldmuntz E, Mitchell LE, Wang T, Emanuel BS, Morrow BE, International 22q11.2 Consortium/Brain and Behavior Consortium*) Circ Cardiovasc Genet 2017 Oct;10(5) PMID: 29025761 PMCID: PMC5647121 10/14/2017    
  • Ventricular Fibrillation and Myocardial Depression Following Pulmonary Valve Replacement in Tetralogy of Fallot With an Intramural Coronary Artery and Coronary Artery Compression by Chest Tube. (Ahmed M, Thompson NE, Foerster SR, Frommelt MA, Mitchell ME, Scott JP) World J Pediatr Congenit Heart Surg 2020 Jul;11(4):NP77-NP79 PMID: 28933244 09/22/2017    
  • Anatomic Repair of Congenitally Corrected Transposition of the Great Arteries: Single-Center Intermediate-Term Experience. (Sachdeva S, Jacobsen RM, Woods RK, Mitchell ME, Cava JR, Ghanayem NS, Frommelt PC, Bartz PJ, Tweddell JS) Pediatr Cardiol 2017 Dec;38(8):1696-1702 PMID: 28918529 SCOPUS ID: 2-s2.0-85029544785 09/18/2017    
  • Single-Stage Repair of Coarctation of the Aorta and Ventricular Septal Defect: A Comparison of Surgical Strategies and Resource Utilization. (Callahan C, Saudek D, Shillingford A, Creighton S, Hill G, Johnson W, Tweddell JS, Mitchell ME, Woods RK) World J Pediatr Congenit Heart Surg 2017 09;8(5):559-563 PMID: 28901231 SCOPUS ID: 2-s2.0-85050578475 09/14/2017       3 Citations
  • Adrenergic receptor genotypes influence postoperative outcomes in infants in the Single-Ventricle Reconstruction Trial. (Ramroop R, Manase G, Lu D, Manase D, Chen S, Kim R, Lee T, Mahle WT, McHugh K, Mitchell M, Tristani-Firouzi M, Wechsler SB, Wilder NS, Zak V, Lafreniere-Roula M, Newburger JW, Gaynor JW, Russell MW, Mital S) J Thorac Cardiovasc Surg 2017 11;154(5):1703-1710.e3 PMID: 28734628 PMCID: PMC5647218 SCOPUS ID: 2-s2.0-85024884367 07/25/2017       3 Citations
  • Aortic Coarctation Repair: How I Teach It. (Mitchell ME) Ann Thorac Surg 2017 Aug;104(2):377-381 PMID: 28734405 SCOPUS ID: 2-s2.0-85025156435 07/25/2017       1 Citation
  • Anesthetic Management of an Infant With Postnatally Diagnosed Tracheal Agenesis Undergoing Tracheal Reconstruction: A Case Report. (Willer BL, Bryan KG, Parakininkas DE, Uhing MR, Staudt SR, Dominguez KM, McCormick ME, Mitchell ME, Densmore JC, Oldham KT, Berens RJ) A A Case Rep 2017 Dec 01;9(11):311-318 PMID: 28719384 07/19/2017    
  • What surgical improvements are needed to prove that anatomic repair is superior to physiologic repair in the majority of patients with corrected transposition of the great arteries? (Hraska V, Mitchell ME, Woods RK, Frommelt MA) J Thorac Cardiovasc Surg 2017 09;154(3):1019-1022 PMID: 28666660 SCOPUS ID: 2-s2.0-85021842736 07/02/2017       4 Citations
  • Neonatal esophageal trachealization and esophagocarinoplasty in the treatment of flow-limited Floyd II tracheal agenesis. (Densmore JC, Oldham KT, Dominguez KM, Berdan ER, McCormick ME, Beste DJ, Amos LB, Lang CA, Woods RK, Kouretas PC, Mitchell ME) J Thorac Cardiovasc Surg 2017 06;153(6):e121-e125 PMID: 28526113 SCOPUS ID: 2-s2.0-85019443267 05/21/2017       4 Citations
  • Hemodynamic Profile of Acute Kidney Injury Following the Fontan Procedure: Impact of Renal Perfusion Pressure. (Patterson T, Hehir DA, Buelow M, Simpson PM, Mitchell ME, Zhang L, Eslami M, Murkowski K, Scott JP) World J Pediatr Congenit Heart Surg 2017 05;8(3):367-375 PMID: 28520545 SCOPUS ID: 2-s2.0-85050577776 05/19/2017       6 Citations
  • Mucopolysaccharidoses Causing Valvular Heart Disease: Report and Review of Surgical Management. (Encarnacion CO, Hang D, Earing M, Mitchell ME) World J Pediatr Congenit Heart Surg 2020 Jul;11(4):NP22-NP24 PMID: 28421916 04/20/2017    
  • Side-to-Side Tracheobronchoplasty to Reconstruct Complex Congenital Tracheobronchial Stenosis. (Ragalie WS, Chun RH, Martin T, Ghanayem NS, Berens RJ, Beste DJ, Mitchell ME) Ann Thorac Surg 2017 Aug;104(2):666-673 PMID: 28366462 SCOPUS ID: 2-s2.0-85016460560 04/04/2017       2 Citations
  • Microvascular surgery in the congenital cardiac patient: A case series exploring feasibility and practical applications. (LoGiudice JA, Adamson K, Ghanayem N, Woods RK, Mitchell ME) J Plast Reconstr Aesthet Surg 2017 May;70(5):639-645 PMID: 28325567 SCOPUS ID: 2-s2.0-85015294699 03/23/2017       1 Citation
  • A 10-Year Review of Total Hospital-Onset ICU Bloodstream Infections at an Academic Medical Center. (Civitarese AM, Ruggieri E, Walz JM, Mack DA, Heard SO, Mitchell M, Lilly CM, Landry KE, Ellison RT 3rd) Chest 2017 05;151(5):1011-1017 PMID: 28215789 02/22/2017       2 Citations
  • Postoperative Cerebral and Somatic Near-Infrared Spectroscopy Saturations and Outcome in Hypoplastic Left Heart Syndrome. (Hoffman GM, Ghanayem NS, Scott JP, Tweddell JS, Mitchell ME, Mussatto KA) Ann Thorac Surg 2017 May;103(5):1527-1535 PMID: 28012642 SCOPUS ID: 2-s2.0-85008153137 12/26/2016       27 Citations
  • Mechanical Circulatory Support of the Fontan Patient. (Woods RK, Ghanayem NS, Mitchell ME, Kindel S, Niebler RA) Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2017 Jan;20:20-27 PMID: 28007060 SCOPUS ID: 2-s2.0-85006384844 12/23/2016       15 Citations
  • Transition in the mechanism of flow-mediated dilation with aging and development of coronary artery disease. (Beyer AM, Zinkevich N, Miller B, Liu Y, Wittenburg AL, Mitchell M, Galdieri R, Sorokin A, Gutterman DD) Basic Res Cardiol 2017 01;112(1):5 PMID: 27995364 PMCID: PMC6758541 SCOPUS ID: 2-s2.0-85006456806 12/21/2016       20 Citations
  • Impact of MYH6 variants in hypoplastic left heart syndrome. (Tomita-Mitchell A, Stamm KD, Mahnke DK, Kim MS, Hidestrand PM, Liang HL, Goetsch MA, Hidestrand M, Simpson P, Pelech AN, Tweddell JS, Benson DW, Lough JW, Mitchell ME) Physiol Genomics 2016 12 01;48(12):912-921 PMID: 27789736 PMCID: PMC5206387 SCOPUS ID: 2-s2.0-85006309110 10/30/2016       19 Citations
  • Ciliopathy variant burden and developmental delay in children with hypoplastic left heart syndrome. (Geddes GC, Stamm K, Mitchell M, Mussatto KA, Tomita-Mitchell A) Genet Med 2017 06;19(6):711-714 PMID: 27787502 SCOPUS ID: 2-s2.0-85020225756 10/28/2016       4 Citations
  • Advances in Surgical Treatment of Congenital Airway Disease. (Ragalie WS, Mitchell ME) Semin Thorac Cardiovasc Surg Spring 2016;28(1):62-8 PMID: 27568138 SCOPUS ID: 2-s2.0-84961827967 08/29/2016       6 Citations
  • Erratum: Long-term outcomes after surgical repair of complete atrioventricular septal defect (Journal of Thoracic and Cardiovascular Surgery (2015) 150 (369-374)) (Ginde S, Lam J, Hill GD, Cohen S, Woods RK, Mitchell ME) Journal of Thoracic and Cardiovascular Surgery 1 July 2016;152(1):292 SCOPUS ID: 2-s2.0-84975524299 07/01/2016    
  • Aortic arch repair in children with PHACE syndrome. (Caragher SP, Scott JP, Siegel DH, Mitchell ME, Frommelt PC, Drolet BA) J Thorac Cardiovasc Surg 2016 09;152(3):709-17 PMID: 27160940 SCOPUS ID: 2-s2.0-84975709026 05/11/2016       7 Citations
  • Secondary Reverse Slide Tracheoplasty for Airway Rescue. (Kopelovich JC, Wine TM, Rutter MJ, Mitchell MB, Prager JD) Ann Thorac Surg 2016 Mar;101(3):1205-7 PMID: 26897214 02/22/2016       3 Citations
  • Metakaryotic cancer stem cells are constitutively resistant to X-rays and chemotherapeutic agents, but sensitive to many common drugs (Gostjeva EV, Koledova VV, Bai L, Duan KC, Kamath T, Nelson M, Agnihotri P, Moshinski DJ, Ping Wu L, Zukerberg L, Chung DC, Tsai S, Evans DB, Tomita-Mitchell A, Mitchell M, Thilly WG) Issues in Toxicology 2016;2016-January(29):196-249 SCOPUS ID: 2-s2.0-84986556373 01/01/2016    
  • A Pilot Study of Antithrombin Replacement Prior to Cardiopulmonary Bypass in Neonates. (Niebler RA, Woods KJ, Murkowski K, Ghanayem NS, Hoffman G, Mitchell ME, Punzalan RC, Scott JP, Simpson P, Tweddell JS) Artif Organs 2016 Jan;40(1):80-5 PMID: 26620919 SCOPUS ID: 2-s2.0-84956825530 12/02/2015       6 Citations
  • Effect of 22q11.2 deletion on bleeding and transfusion utilization in children with congenital heart disease undergoing cardiac surgery. (Brenner MK, Clarke S, Mahnke DK, Simpson P, Bercovitz RS, Tomita-Mitchell A, Mitchell ME, Newman DK) Pediatr Res 2016 Feb;79(2):318-24 PMID: 26492284 PMCID: PMC5114022 SCOPUS ID: 2-s2.0-84982285447 10/23/2015       13 Citations
  • Impact of Intrauterine Growth Restriction on Cardiac Surgical Outcomes and Resource Use. (Graf R, Ghanayem NS, Hoffmann R, Dasgupta M, Kessel M, Mitchell ME, Tweddell JS, Woods RK) Ann Thorac Surg 2015 Oct;100(4):1411-5 PMID: 26279364 SCOPUS ID: 2-s2.0-84952718931 08/19/2015       5 Citations
  • Ventricular Assist Device in Single-Ventricle Heart Disease and a Superior Cavopulmonary Anastomosis. (Niebler RA, Shah TK, Mitchell ME, Woods RK, Zangwill SD, Tweddell JS, Berger S, Ghanayem NS) Artif Organs 2016 Feb;40(2):180-4 PMID: 26147841 SCOPUS ID: 2-s2.0-84955637072 07/07/2015       10 Citations
  • The Externally Supported Ross Operation: Early Outcomes and Intermediate Follow-Up. (Jacobsen RM, Earing MG, Hill GD, Barnes M, Mitchell ME, Woods RK, Tweddell JS) Ann Thorac Surg 2015 Aug;100(2):631-8 PMID: 26141776 SCOPUS ID: 2-s2.0-84938695226 07/05/2015       7 Citations
  • Long-term outcomes after surgical repair of complete atrioventricular septal defect. (Ginde S, Lam J, Hill GD, Cohen S, Woods RK, Mitchell ME, Tweddell JS, Earing MG) J Thorac Cardiovasc Surg 2015 Aug;150(2):369-74 PMID: 26048271 SCOPUS ID: 2-s2.0-84937408117 06/07/2015       32 Citations
  • An initial report of a novel multi-institutional bladder exstrophy consortium: a collaboration focused on primary surgery and subsequent care. (Borer JG, Vasquez E, Canning DA, Kryger JV, Mitchell ME) J Urol 2015 May;193(5 Suppl):1802-7 PMID: 25813562 SCOPUS ID: 2-s2.0-84927912011 03/31/2015       18 Citations
  • Use of cell-free fetal DNA in maternal plasma for noninvasive prenatal screening. (Wagner AJ, Mitchell ME, Tomita-Mitchell A) Clin Perinatol 2014 Dec;41(4):957-66 PMID: 25459783 SCOPUS ID: 2-s2.0-84910116657 12/03/2014       14 Citations
  • Anterior tracheal suspension for tracheobronchomalacia in infants and children. (Mitchell ME, Rumman N, Chun RH, Rao A, Martin T, Beste DJ, Berens RJ, Parakininkas DE, Ghanayem NS, Hubert MJ, Uhing M, Simpson P, Sato TT, Tweddell JS, Kerschner JE) Ann Thorac Surg 2014 Oct;98(4):1246-53 PMID: 25086944 SCOPUS ID: 2-s2.0-84908108437 08/05/2014       13 Citations
  • An Unusual Case of Severe Stenosis of the Coronary Sinus Ostium in Association With Double Inlet Left Ventricle. (Hidestrand PM, Kirkpatrick EC, Mitchell ME) World J Pediatr Congenit Heart Surg 2014 07;5(3):473-4 PMID: 24958056 SCOPUS ID: 2-s2.0-84993729245 06/25/2014       2 Citations
  • Use of a HeartWare ventricular assist device in a patient with failed Fontan circulation. (Niebler RA, Ghanayem NS, Shah TK, De La Rosa Bobke A, Zangwill S, Brosig C, Frommelt MA, Mitchell ME, Tweddell JS, Woods RK) Ann Thorac Surg 2014 Apr;97(4):e115-6 PMID: 24694452 SCOPUS ID: 2-s2.0-84897389074 04/04/2014       39 Citations
  • Transposition of the great arteries--outcomes and time interval of early neonatal repair. (Cain MT, Cao Y, Ghanayem NS, Simpson PM, Trapp K, Mitchell ME, Tweddell JS, Woods RK) World J Pediatr Congenit Heart Surg 2014 Apr;5(2):241-7 PMID: 24668972 SCOPUS ID: 2-s2.0-84905175622 03/29/2014       10 Citations
  • Repeated aortopulmonary shunt thrombosis in a neonatal patient with a low antithrombin level. (Niebler RA, Mitchell ME, Scott JP) World J Pediatr Congenit Heart Surg 2014 Jan 01;5(1):94-6 PMID: 24403363 SCOPUS ID: 2-s2.0-84907663865 01/10/2014       1 Citation
  • Aortopulmonary window (Ballmoos MCWV, Barnes M, Berger S, Mitchell ME, Tweddell JS) Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care 1 January 2014:1493-1504 SCOPUS ID: 2-s2.0-84961372844 01/01/2014    
  • Changes in cerebral oxygen saturation correlate with S100B in infants undergoing cardiac surgery with cardiopulmonary bypass. (Abu-Sultaneh S, Hehir DA, Murkowski K, Ghanayem NS, Liedel J, Hoffmann RG, Cao Y, Mitchell ME, Jeromin A, Tweddell JS, Hoffman GM) Pediatr Crit Care Med 2014 Mar;15(3):219-28 PMID: 24366505 SCOPUS ID: 2-s2.0-84896398976 12/25/2013       16 Citations
  • Simulating One-Photon Absorption and Resonance Raman Scattering Spectra Using Analytical Excited State Energy Gradients within Time-Dependent Density Functional Theory. (Silverstein DW, Govind N, van Dam HJ, Jensen L) J Chem Theory Comput 2013 Dec 10;9(12):5490-503 PMID: 26592284 12/10/2013    
  • Incidence and outcome of pediatric patients with intracranial hemorrhage while supported on ventricular assist devices. (Niebler RA, Lew SM, Zangwill SD, Woods RK, Mitchell ME, Tweddell JS, Ghanayem NS) Artif Organs 2014 Jan;38(1):73-8 PMID: 24256117 SCOPUS ID: 2-s2.0-84891903265 11/22/2013       4 Citations
  • Outcomes of systemic to pulmonary artery shunts in patients weighing less than 3 kg: analysis of shunt type, size, and surgical approach. (Myers JW, Ghanayem NS, Cao Y, Simpson P, Trapp K, Mitchell ME, Tweddell JS, Woods RK) J Thorac Cardiovasc Surg 2014 Feb;147(2):672-7 PMID: 24252942 SCOPUS ID: 2-s2.0-84892369049 11/21/2013       34 Citations
  • Highly sensitive noninvasive cardiac transplant rejection monitoring using targeted quantification of donor-specific cell-free deoxyribonucleic acid. (Hidestrand M, Tomita-Mitchell A, Hidestrand PM, Oliphant A, Goetsch M, Stamm K, Liang HL, Castleberry C, Benson DW, Stendahl G, Simpson PM, Berger S, Tweddell JS, Zangwill S, Mitchell ME) J Am Coll Cardiol 2014 Apr 01;63(12):1224-1226 PMID: 24140666 PMCID: PMC4988656 SCOPUS ID: 2-s2.0-84896944581 10/22/2013       41 Citations
  • Extracorporeal membrane oxygenation versus counterpulsatile, pulsatile, and continuous left ventricular unloading for pediatric mechanical circulatory support. (Bartoli CR, Koenig SC, Ionan C, Gillars KJ, Mitchell ME, Austin EH 3rd, Gray LA, Pantalos GM) Pediatr Crit Care Med 2013 Nov;14(9):e424-37 PMID: 24108116 PMCID: PMC3913264 SCOPUS ID: 2-s2.0-84892807632 10/11/2013       5 Citations
  • Bilateral pulmonary artery banding as rescue intervention in high-risk neonates. (Russell RA, Ghanayem NS, Mitchell ME, Woods RK, Tweddell JS) Ann Thorac Surg 2013 Sep;96(3):885-90 PMID: 23916808 SCOPUS ID: 2-s2.0-84883239384 08/07/2013       13 Citations
  • Thromboelastography in the assessment of bleeding following surgery for congenital heart disease. (Niebler RA, Gill JC, Brabant CP, Mitchell ME, Nugent M, Simpson P, Tweddell JS, Ghanayem NS) World J Pediatr Congenit Heart Surg 2012 Oct 01;3(4):433-8 PMID: 23804904 06/28/2013    
  • Mechanical support as failure intervention in patients with cavopulmonary shunts (MFICS): rationale and aims of a new registry of mechanical circulatory support in single ventricle patients. (Rossano JW, Woods RK, Berger S, Gaynor JW, Ghanayem N, Morales DL, Ravishankar C, Mitchell ME, Shah TK, Mahr C, Tweddell JS, Adachi I, Zangwill S, Wearden PD, Icenogle TB, Jaquiss RD, Rychik J) Congenit Heart Dis 2013 May-Jun;8(3):182-6 PMID: 23510301 SCOPUS ID: 2-s2.0-84878732295 03/21/2013       36 Citations
  • MRI validated echocardiographic technique to measure total cardiac volume: a tool for donor-recipient size matching in pediatric heart transplantation. (Camarda J, Saudek D, Tweddell J, Mitchell M, Woods R, Otto M, Simpson P, Stendahl G, Berger S, Zangwill S) Pediatr Transplant 2013 May;17(3):300-6 PMID: 23489637 PMCID: PMC4662949 SCOPUS ID: 2-s2.0-84876712340 03/16/2013       11 Citations
  • Aortic valve replacement in neonates and infants: an analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database. (Woods RK, Pasquali SK, Jacobs ML, Austin EH, Jacobs JP, Krolikowski M, Mitchell ME, Pizarro C, Tweddell JS) J Thorac Cardiovasc Surg 2012 Nov;144(5):1084-89 PMID: 22921819 SCOPUS ID: 2-s2.0-84865154955 08/28/2012       25 Citations
  • Valve-sparing aortic root reconstruction in children, teenagers, and young adults. (Tweddell JS, Earing MG, Bartz PJ, Dunham-Ingles JL, Woods RK, Mitchell ME) Ann Thorac Surg 2012 Aug;94(2):587-90; discussion 590-1 PMID: 22748646 SCOPUS ID: 2-s2.0-84864186345 07/04/2012       10 Citations
  • Human gene copy number spectra analysis in congenital heart malformations. (Tomita-Mitchell A, Mahnke DK, Struble CA, Tuffnell ME, Stamm KD, Hidestrand M, Harris SE, Goetsch MA, Simpson PM, Bick DP, Broeckel U, Pelech AN, Tweddell JS, Mitchell ME) Physiol Genomics 2012 May 01;44(9):518-41 PMID: 22318994 PMCID: PMC3426426 SCOPUS ID: 2-s2.0-84862128193 02/10/2012       63 Citations
  • Pulmonary atresia with intact ventricular septum (Mitchell ME, Barnes ME, Tweddell JS) Cardiothoracic Surgery Review 5 January 2012:1600-1603 SCOPUS ID: 2-s2.0-84976566062 01/05/2012    
  • Tetralogy of fallot, including tetralogy of fallot with pulmonary stenosis, pulmonary atresia and tetralogy of fallot with pulmonary atresia and major aortopulmonary collateral arteries (Barnes ME, Tweddell JS, Mitchell ME) Cardiothoracic Surgery Review 5 January 2012:1604-1609 SCOPUS ID: 2-s2.0-84976533700 01/05/2012    
  • Coarctectomy combined with an interdigitating arch reconstruction results in a lower incidence of recurrent arch obstruction after the Norwood procedure than coarctectomy alone. (Lamers LJ, Frommelt PC, Mussatto KA, Jaquiss RD, Mitchell ME, Tweddell JS) J Thorac Cardiovasc Surg 2012 May;143(5):1098-102 PMID: 22050986 PMCID: PMC4606923 SCOPUS ID: 2-s2.0-84859757034 11/05/2011       30 Citations
  • Aortic exclusion: a method of handling aortic insufficiency in the pediatric population needing mechanical circulatory support. (Gandy KL, Mitchell ME, Pelech AN, Niebler RA, Hoffman G, Berger S) Pediatr Cardiol 2011 Dec;32(8):1231-3 PMID: 21809133 SCOPUS ID: 2-s2.0-83555165034 08/03/2011       6 Citations
  • Phylogenomic evidence for a myxococcal contribution to the mitochondrial fatty acid beta-oxidation. (Schlüter A, Ruiz-Trillo I, Pujol A) PLoS One 2011;6(7):e21989 PMID: 21760940 PMCID: PMC3131387 07/16/2011       4 Citations
  • Aortopulmonary window. (Barnes ME, Mitchell ME, Tweddell JS) Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2011;14(1):67-74 PMID: 21444051 SCOPUS ID: 2-s2.0-79953066772 03/30/2011       23 Citations
  • Surgery and critical care for anomalous coronary artery from the pulmonary artery. (Fehrenbacher TA, Mitchell ME, Ghanayem NS, Tweddell JS) Cardiol Young 2010 Dec;20 Suppl 3:35-43 PMID: 21087558 SCOPUS ID: 2-s2.0-79953827828 11/23/2010       3 Citations
  • Humoral rejection after pediatric heart transplantation: a case report. (Stendahl G, Berger S, Ellis T, Gandy K, Mitchell M, Tweddell J, Zangwill S) Prog Transplant 2010 Sep;20(3):288-91 PMID: 20929115 SCOPUS ID: 2-s2.0-79952063346 10/12/2010       11 Citations
  • Perioperative monitoring in high-risk infants after stage 1 palliation of univentricular congenital heart disease. (Ghanayem NS, Hoffman GM, Mussatto KA, Frommelt MA, Cava JR, Mitchell ME, Tweddell JS) J Thorac Cardiovasc Surg 2010 Oct;140(4):857-63 PMID: 20621312 SCOPUS ID: 2-s2.0-77956885774 07/14/2010       53 Citations
  • Surgical repair of pulmonary arterial stenosis (Mitchell ME, Tweddell JS) Congenital Diseases in the Right Heart 2009:85-91 SCOPUS ID: 2-s2.0-84889957511 12/01/2009    
  • Fontan palliation in the modern era: factors impacting mortality and morbidity. (Tweddell JS, Nersesian M, Mussatto KA, Nugent M, Simpson P, Mitchell ME, Ghanayem NS, Pelech AN, Marla R, Hoffman GM) Ann Thorac Surg 2009 Oct;88(4):1291-9 PMID: 19766824 SCOPUS ID: 2-s2.0-70349188689 09/22/2009       113 Citations
  • Hypersensitivity reactions to aprotinin re-exposure in paediatric surgery. (Siehr S, Stuth E, Tweddell J, Hoffman G, Troshynski T, Jones D, Mitchell M, Ghanayem N) Eur J Cardiothorac Surg 2010 Feb;37(2):307-11 PMID: 19767215 SCOPUS ID: 2-s2.0-74249101769 09/22/2009       6 Citations
  • Invited commentary. (Mitchell ME) Ann Thorac Surg 2009 Jul;88(1):176 PMID: 19559220 SCOPUS ID: 2-s2.0-67649781604 06/30/2009    
  • Investigation of somatic NKX2-5 mutations in congenital heart disease. (Draus JM Jr, Hauck MA, Goetsch M, Austin EH 3rd, Tomita-Mitchell A, Mitchell ME) J Med Genet 2009 Feb;46(2):115-22 PMID: 19181906 PMCID: PMC2628540 SCOPUS ID: 2-s2.0-62149117229 02/03/2009       50 Citations
  • Near-infrared spectroscopy in neonates before palliation of hypoplastic left heart syndrome. (Johnson BA, Hoffman GM, Tweddell JS, Cava JR, Basir M, Mitchell ME, Scanlon MC, Mussatto KA, Ghanayem NS) Ann Thorac Surg 2009 Feb;87(2):571-7; discussion 577-9 PMID: 19161781 SCOPUS ID: 2-s2.0-58249137786 01/24/2009       69 Citations
  • Midaortic syndrome presenting as neonatal hypertension. (Das BB, Recto M, Shoemaker L, Mitchell M, Austin EH) Pediatr Cardiol 2008 Sep;29(5):1000-1 PMID: 18060446 SCOPUS ID: 2-s2.0-50649114923 12/07/2007       16 Citations
  • The molecular basis of congenital heart disease. (Mitchell ME, Sander TL, Klinkner DB, Tomita-Mitchell A) Semin Thorac Cardiovasc Surg 2007;19(3):228-37 PMID: 17983950 SCOPUS ID: 2-s2.0-35748971489 11/07/2007       40 Citations
  • Mixed venous oxygen saturation monitoring after stage 1 palliation for hypoplastic left heart syndrome. (Tweddell JS, Ghanayem NS, Mussatto KA, Mitchell ME, Lamers LJ, Musa NL, Berger S, Litwin SB, Hoffman GM) Ann Thorac Surg 2007 Oct;84(4):1301-10; discussion 1310-1 PMID: 17888987 SCOPUS ID: 2-s2.0-34548661975 09/25/2007       99 Citations
  • Effect of continuous and pulsatile flow left ventricular assist on pulsatility in a pediatric animal model of left ventricular dysfunction: pilot observations. (Pantalos GM, Giridharan G, Colyer J, Mitchell M, Speakman J, Lucci C, Johnson G, Gartner M, Koenig SC) ASAIO J 2007 May-Jun;53(3):385-91 PMID: 17515734 SCOPUS ID: 2-s2.0-34249014596 05/23/2007       20 Citations
  • Complex atrioventricular canal. (Mitchell ME, Litwin SB, Tweddell JS) Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2007:32-41 PMID: 17433989 SCOPUS ID: 2-s2.0-34147144172 04/17/2007       11 Citations
  • The double patch repair for complete atrioventricularis communis. (Litwin SB, Tweddell JS, Mitchell ME, Mussatto KA) Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2007:21-7 PMID: 17433987 SCOPUS ID: 2-s2.0-34147207371 04/17/2007       20 Citations
  • Monitoring the brain before, during, and after cardiac surgery to improve long-term neurodevelopmental outcomes. (Ghanayem NS, Mitchell ME, Tweddell JS, Hoffman GM) Cardiol Young 2006 Sep;16 Suppl 3:103-9 PMID: 17378048 SCOPUS ID: 2-s2.0-33750214288 03/23/2007       23 Citations
  • A computer model of the pediatric circulatory system for testing pediatric assist devices. (Giridharan GA, Koenig SC, Mitchell M, Gartner M, Pantalos GM) ASAIO J 2007 Jan-Feb;53(1):74-81 PMID: 17237652 SCOPUS ID: 2-s2.0-33846458303 01/24/2007       12 Citations
  • Molecular and cellular basis of congenital heart disease. (Sander TL, Klinkner DB, Tomita-Mitchell A, Mitchell ME) Pediatr Clin North Am 2006 Oct;53(5):989-1009, x PMID: 17027620 SCOPUS ID: 2-s2.0-33749431116 10/10/2006       16 Citations
  • Cardiac transplantation for pediatric giant cell myocarditis. (Das BB, Recto M, Johnsrude C, Klein L, Orman K, Shoemaker L, Mitchell M, Austin EH) J Heart Lung Transplant 2006 Apr;25(4):474-8 PMID: 16563980 SCOPUS ID: 2-s2.0-33645049103 03/28/2006       16 Citations
  • Intermediate outcomes after the Fontan procedure in the current era. (Mitchell ME, Ittenbach RF, Gaynor JW, Wernovsky G, Nicolson S, Spray TL) J Thorac Cardiovasc Surg 2006 Jan;131(1):172-80 PMID: 16399309 SCOPUS ID: 2-s2.0-30044440855 01/10/2006       89 Citations
  • Seven-year clinical experience with the extracardiac pedicled pericardial Fontan operation. (Kavarana MN, Pagni S, Recto MR, Sobczyk WL, Yeh T Jr, Mitchell M, Austin EH 3rd) Ann Thorac Surg 2005 Jul;80(1):37-43; discussion 43 PMID: 15975336 SCOPUS ID: 2-s2.0-20544436978 06/25/2005       10 Citations
  • Use of recombinant factor VIIa for refractory hemorrhage during extracorporeal membrane oxygenation. (Dominguez TE, Mitchell M, Friess SH, Huh JW, Manno CS, Ravishankar C, Gaynor JW, Tabbutt S) Pediatr Crit Care Med 2005 May;6(3):348-51 PMID: 15857537 SCOPUS ID: 2-s2.0-19444375493 04/29/2005       45 Citations
  • Minimally invasive mitral valve repair suggests earlier operations for mitral valve disease. (Greelish JP, Cohn LH, Leacche M, Mitchell M, Karavas A, Fox J, Byrne JG, Aranki SF, Couper GS) J Thorac Cardiovasc Surg 2003 Aug;126(2):365-71; discussion 371-3 PMID: 12928632 SCOPUS ID: 2-s2.0-0041353796 08/21/2003       61 Citations
  • Minimally invasive direct access for repair of atrial septal defect in adults. (Byrne JG, Adams DH, Mitchell ME, Cohn LH) Am J Cardiol 1999 Oct 15;84(8):919-22 PMID: 10532511 SCOPUS ID: 2-s2.0-0032826813 10/26/1999       20 Citations
  • Minimally invasive direct access mitral valve surgery. (Byrne JG, Mitchell ME, Adams DH, Couper GS, Aranki SF, Cohn LH) Semin Thorac Cardiovasc Surg 1999 Jul;11(3):212-22 PMID: 10451252 SCOPUS ID: 2-s2.0-0033158305 08/18/1999       13 Citations
  • Last update: 09/16/2020
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