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Akiko Mammoto MD, PhD

Akiko Mammoto MD, PhD profile photo picture

Associate Professor

Institution: Medical College of Wisconsin
Department: Pediatrics
Division: Neonatology

Member of the Cardiovascular Center


Publications (88)

  • Endothelial Twist1-PDGFB signaling mediates hypoxia-induced proliferation and migration of αSMA-positive cells. (Mammoto A, Hendee K, Muyleart M, Mammoto T) Sci Rep 2020 May 05;10(1):7563 PMID: 32371931 PMCID: PMC7200682 SCOPUS ID: 2-s2.0-85084328882 05/07/2020    
  • Author Correction: Shear stress induces endothelial-to-mesenchymal transition via the transcription factor Snail. (Mahmoud MM, Serbanovic-Canic J, Feng S, Souilhol C, Xing R, Hsiao S, Mammoto A, Chen J, Ariaans M, Francis SE, Van der Heiden K, Ridger V, Evans PC) Sci Rep 2020 Feb 26;10(1):3870 PMID: 32099026 PMCID: PMC7042236 SCOPUS ID: 2-s2.0-85080837040 02/27/2020    
  • Vascular Niche in Lung Alveolar Development, Homeostasis, and Regeneration. (Mammoto A, Mammoto T) Front Bioeng Biotechnol 2019;7:318 PMID: 31781555 PMCID: PMC6861452 SCOPUS ID: 2-s2.0-85075893514 11/30/2019    
  • Effects of age-dependent changes in cell size on endothelial cell proliferation and senescence through YAP1. (Mammoto T, Torisawa YS, Muyleart M, Hendee K, Anugwom C, Gutterman D, Mammoto A) Aging (Albany NY) 2019 09 05;11(17):7051-7069 PMID: 31487690 PMCID: PMC6756888 SCOPUS ID: 2-s2.0-85072345071 09/06/2019       2 Citations
  • Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models. (Papa AL, Jiang A, Korin N, Chen MB, Langan ET, Waterhouse A, Nash E, Caroff J, Graveline A, Vernet A, Mammoto A, Mammoto T, Jain A, Kamm RD, Gounis MJ, Ingber DE) Sci Transl Med 2019 02 13;11(479) PMID: 30760580 SCOPUS ID: 2-s2.0-85061618001 02/15/2019       10 Citations
  • LRP5 in age-related changes in vascular and alveolar morphogenesis in the lung. (Mammoto A, Muyleart M, Mammoto T) Aging (Albany NY) 2019 01 05;11(1):89-103 PMID: 30612120 PMCID: PMC6339783 SCOPUS ID: 2-s2.0-85060053785 01/07/2019       4 Citations
  • Endothelial YAP1 in Regenerative Lung Growth through the Angiopoietin-Tie2 Pathway. (Mammoto T, Muyleart M, Mammoto A) Am J Respir Cell Mol Biol 2019 01;60(1):117-127 PMID: 30156429 PMCID: PMC6348720 SCOPUS ID: 2-s2.0-85059234576 08/30/2018       5 Citations
  • YAP1-TEAD1 signaling controls angiogenesis and mitochondrial biogenesis through PGC1α. (Mammoto A, Muyleart M, Kadlec A, Gutterman D, Mammoto T) Microvasc Res 2018 09;119:73-83 PMID: 29680477 PMCID: PMC6005762 SCOPUS ID: 2-s2.0-85046667624 04/24/2018       12 Citations
  • Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip. (Musah S, Mammoto A, Ferrante TC, Jeanty SSF, Hirano-Kobayashi M, Mammoto T, Roberts K, Chung S, Novak R, Ingram M, Fatanat-Didar T, Koshy S, Weaver JC, Church GM, Ingber DE) Nat Biomed Eng 2017;1 PMID: 29038743 PMCID: PMC5639718 10/19/2017    
  • Twist1 in Hypoxia-induced Pulmonary Hypertension through Transforming Growth Factor-β-Smad Signaling. (Mammoto T, Muyleart M, Konduri GG, Mammoto A) Am J Respir Cell Mol Biol 2018 02;58(2):194-207 PMID: 28915063 SCOPUS ID: 2-s2.0-85043329586 09/16/2017       22 Citations
  • An Engineered Human Fc-Mannose-Binding-Lectin Captures Circulating Tumor Cells (Kang JH, Driscoll H, Mammoto A, Watters AL, Melakeberhan B, Diaz A, Super M, Ingber DE) Advanced Biosystems July 2017;1(7) SCOPUS ID: 2-s2.0-85060284142 07/01/2017    
  • An Engineered Human Fc-Mannose-Binding-Lectin Captures Circulating Tumor Cells. (Kang JH, Driscoll H, Mammoto A, Watters AL, Melakeberhan B, Diaz A, Super M, Ingber DE) Adv Biosyst 2017 Jul;1(7):e1700094 PMID: 32646174 07/01/2017    
  • Ultrasound-sensitive nanoparticle aggregates for targeted drug delivery. (Papa AL, Korin N, Kanapathipillai M, Mammoto A, Mammoto T, Jiang A, Mannix R, Uzun O, Johnson C, Bhatta D, Cuneo G, Ingber DE) Biomaterials 2017 Sep;139:187-194 PMID: 28618348 SCOPUS ID: 2-s2.0-85020633088 06/16/2017       25 Citations
  • Shear stress induces endothelial-to-mesenchymal transition via the transcription factor Snail. (Mahmoud MM, Serbanovic-Canic J, Feng S, Souilhol C, Xing R, Hsiao S, Mammoto A, Chen J, Ariaans M, Francis SE, Van der Heiden K, Ridger V, Evans PC) Sci Rep 2017 06 13;7(1):3375 PMID: 28611395 PMCID: PMC5469771 SCOPUS ID: 2-s2.0-85020913417 06/15/2017       39 Citations
  • Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics. (Jain A, Barrile R, van der Meer AD, Mammoto A, Mammoto T, De Ceunynck K, Aisiku O, Otieno MA, Louden CS, Hamilton GA, Flaumenhaft R, Ingber DE) Clin Pharmacol Ther 2018 02;103(2):332-340 PMID: 28516446 PMCID: PMC5693794 SCOPUS ID: 2-s2.0-85023770580 05/19/2017       67 Citations
  • Role of Twist1 Phosphorylation in Angiogenesis and Pulmonary Fibrosis. (Mammoto T, Jiang A, Jiang E, Mammoto A) Am J Respir Cell Mol Biol 2016 11;55(5):633-644 PMID: 27281171 SCOPUS ID: 2-s2.0-84994417658 11/01/2016       19 Citations
  • TWIST1 Integrates Endothelial Responses to Flow in Vascular Dysfunction and Atherosclerosis. (Mahmoud MM, Kim HR, Xing R, Hsiao S, Mammoto A, Chen J, Serbanovic-Canic J, Feng S, Bowden NP, Maguire R, Ariaans M, Francis SE, Weinberg PD, van der Heiden K, Jones EA, Chico TJ, Ridger V, Evans PC) Circ Res 2016 07 22;119(3):450-62 PMID: 27245171 PMCID: PMC4959828 SCOPUS ID: 2-s2.0-84973327121 06/02/2016       38 Citations
  • Modeling Hematopoiesis and Responses to Radiation Countermeasures in a Bone Marrow-on-a-Chip. (Torisawa YS, Mammoto T, Jiang E, Jiang A, Mammoto A, Watters AL, Bahinski A, Ingber DE) Tissue Eng Part C Methods 2016 05;22(5):509-15 PMID: 26993746 SCOPUS ID: 2-s2.0-84969179664 03/20/2016       15 Citations
  • Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation. (Huebsch N, Lippens E, Lee K, Mehta M, Koshy ST, Darnell MC, Desai RM, Madl CM, Xu M, Zhao X, Chaudhuri O, Verbeke C, Kim WS, Alim K, Mammoto A, Ingber DE, Duda GN, Mooney DJ) Nat Mater 2015 Dec;14(12):1269-77 PMID: 26366848 PMCID: PMC4654683 SCOPUS ID: 2-s2.0-84947868969 09/15/2015       215 Citations
  • VEGF-A/NRP1 stimulates GIPC1 and Syx complex formation to promote RhoA activation and proliferation in skin cancer cells. (Yoshida A, Shimizu A, Asano H, Kadonosono T, Kondoh SK, Geretti E, Mammoto A, Klagsbrun M, Seo MK) Biol Open 2015 Jul 24;4(9):1063-76 PMID: 26209534 PMCID: PMC4582117 07/26/2015    
  • Acceleration of Lung Regeneration by Platelet-Rich Plasma Extract through the Low-Density Lipoprotein Receptor-Related Protein 5-Tie2 Pathway. (Mammoto T, Chen Z, Jiang A, Jiang E, Ingber DE, Mammoto A) Am J Respir Cell Mol Biol 2016 Jan;54(1):103-13 PMID: 26091161 PMCID: PMC5455682 SCOPUS ID: 2-s2.0-85047289720 06/20/2015       10 Citations
  • Mesenchymal condensation-dependent accumulation of collagen VI stabilizes organ-specific cell fates during embryonic tooth formation. (Mammoto T, Mammoto A, Jiang A, Jiang E, Hashmi B, Ingber DE) Dev Dyn 2015 Jun;244(6):713-23 PMID: 25715693 PMCID: PMC4449280 SCOPUS ID: 2-s2.0-84929952646 02/27/2015       9 Citations
  • Implantation of fibrin gel on mouse lung to study lung-specific angiogenesis. (Mammoto T, Mammoto A) J Vis Exp 2014 Dec 21(94) PMID: 25548859 PMCID: PMC4396947 SCOPUS ID: 2-s2.0-84921634387 12/31/2014       11 Citations
  • Endothelial TWIST1 promotes pathological ocular angiogenesis. (Li J, Liu CH, Sun Y, Gong Y, Fu Z, Evans LP, Tian KT, Juan AM, Hurst CG, Mammoto A, Chen J) Invest Ophthalmol Vis Sci 2014 Nov 20;55(12):8267-77 PMID: 25414194 PMCID: PMC4541480 SCOPUS ID: 2-s2.0-84919360479 11/22/2014       24 Citations
  • An extracorporeal blood-cleansing device for sepsis therapy. (Kang JH, Super M, Yung CW, Cooper RM, Domansky K, Graveline AR, Mammoto T, Berthet JB, Tobin H, Cartwright MJ, Watters AL, Rottman M, Waterhouse A, Mammoto A, Gamini N, Rodas MJ, Kole A, Jiang A, Valentin TM, Diaz A, Takahashi K, Ingber DE) Nat Med 2014 Oct;20(10):1211-6 PMID: 25216635 SCOPUS ID: 2-s2.0-84911445227 09/14/2014       154 Citations
  • Platelet-rich plasma extract prevents pulmonary edema through angiopoietin-Tie2 signaling. (Mammoto T, Jiang A, Jiang E, Mammoto A) Am J Respir Cell Mol Biol 2015 Jan;52(1):56-64 PMID: 24960457 PMCID: PMC5455304 SCOPUS ID: 2-s2.0-84920278242 06/25/2014       11 Citations
  • RASA1 functions in EPHB4 signaling pathway to suppress endothelial mTORC1 activity. (Kawasaki J, Aegerter S, Fevurly RD, Mammoto A, Mammoto T, Sahin M, Mably JD, Fishman SJ, Chan J) J Clin Invest 2014 Jun;124(6):2774-84 PMID: 24837431 PMCID: PMC4089464 SCOPUS ID: 2-s2.0-84902180002 05/20/2014       31 Citations
  • Netrin-1 promotes medulloblastoma cell invasiveness and angiogenesis, and demonstrates elevated expression in tumor tissue and urine of patients with pediatric medulloblastoma. (Akino T, Han X, Nakayama H, McNeish B, Zurakowski D, Mammoto A, Klagsbrun M, Smith E) Cancer Res 2014 Jul 15;74(14):3716-26 PMID: 24812271 PMCID: PMC4123751 SCOPUS ID: 2-s2.0-84904247223 05/09/2014       33 Citations
  • Bone marrow-on-a-chip replicates hematopoietic niche physiology in vitro. (Torisawa YS, Spina CS, Mammoto T, Mammoto A, Weaver JC, Tat T, Collins JJ, Ingber DE) Nat Methods 2014 Jun;11(6):663-9 PMID: 24793454 SCOPUS ID: 2-s2.0-84901823942 05/06/2014       199 Citations
  • Developmentally-inspired shrink-wrap polymers for mechanical induction of tissue differentiation. (Hashmi B, Zarzar LD, Mammoto T, Mammoto A, Jiang A, Aizenberg J, Ingber DE) Adv Mater 2014 May 28;26(20):3253-7 PMID: 24550068 PMCID: PMC4146397 SCOPUS ID: 2-s2.0-84901485098 02/20/2014       13 Citations
  • Mechanotransduction of fluid stresses governs 3D cell migration. (Polacheck WJ, German AE, Mammoto A, Ingber DE, Kamm RD) Proc Natl Acad Sci U S A 2014 Feb 18;111(7):2447-52 PMID: 24550267 PMCID: PMC3932905 SCOPUS ID: 2-s2.0-84894380551 02/20/2014       122 Citations
  • Paxillin controls endothelial cell migration and tumor angiogenesis by altering neuropilin 2 expression. (German AE, Mammoto T, Jiang E, Ingber DE, Mammoto A) J Cell Sci 2014 Apr 15;127(Pt 8):1672-83 PMID: 24522185 PMCID: PMC3986673 SCOPUS ID: 2-s2.0-84898913240 02/14/2014       21 Citations
  • Biospleen device for extracorporeal sepsis therapy (Kang JH, Super M, Yung CW, Cooper RM, Domansky K, Graveline AR, Mammoto T, Berthet JB, Tobin H, Cartwright MJ, Watters AL, Rottman M, Waterhouse A, Mammoto A, Gamini N, Rodas MJ, Kole A, Jiang A, Valentin TM, Diaz A, Ingber DE) 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 2014:2516-2517 SCOPUS ID: 2-s2.0-84941696089 01/01/2014    
  • Mechanobiology and developmental control. (Mammoto T, Mammoto A, Ingber DE) Annu Rev Cell Dev Biol 2013;29:27-61 PMID: 24099083 SCOPUS ID: 2-s2.0-84904240136 10/09/2013       198 Citations
  • Twist1 controls lung vascular permeability and endotoxin-induced pulmonary edema by altering Tie2 expression. (Mammoto T, Jiang E, Jiang A, Lu Y, Juan AM, Chen J, Mammoto A) PLoS One 2013;8(9):e73407 PMID: 24023872 PMCID: PMC3759405 SCOPUS ID: 2-s2.0-84897402975 09/12/2013       18 Citations
  • Role of collagen matrix in tumor angiogenesis and glioblastoma multiforme progression. (Mammoto T, Jiang A, Jiang E, Panigrahy D, Kieran MW, Mammoto A) Am J Pathol 2013 Oct;183(4):1293-1305 PMID: 23928381 PMCID: PMC3791684 SCOPUS ID: 2-s2.0-84884545390 08/10/2013       62 Citations
  • Epoxyeicosanoids promote organ and tissue regeneration. (Panigrahy D, Kalish BT, Huang S, Bielenberg DR, Le HD, Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Jenkins RL, Simpson MA, Akino T, Lih FB, Tomer KB, Ingber DE, Hammock BD, Falck JR, Manthati VL, Kaipainen A, D'Amore PA, Puder M, Zeldin DC, Kieran MW) Proc Natl Acad Sci U S A 2013 Aug 13;110(33):13528-33 PMID: 23898174 PMCID: PMC3746918 SCOPUS ID: 2-s2.0-84882380783 07/31/2013       88 Citations
  • GATA2 and Lmo2 control angiogenesis and lymphangiogenesis via direct transcriptional regulation of neuropilin-2. (Coma S, Allard-Ratick M, Akino T, van Meeteren LA, Mammoto A, Klagsbrun M) Angiogenesis 2013 Oct;16(4):939-52 PMID: 23892628 PMCID: PMC3793839 SCOPUS ID: 2-s2.0-84884815240 07/31/2013       23 Citations
  • Extracellular matrix structure and tissue stiffness control postnatal lung development through the lipoprotein receptor-related protein 5/Tie2 signaling system. (Mammoto T, Jiang E, Jiang A, Mammoto A) Am J Respir Cell Mol Biol 2013 Dec;49(6):1009-18 PMID: 23841513 SCOPUS ID: 2-s2.0-84890045883 07/12/2013       39 Citations
  • Breast cancer normalization induced by embryonic mesenchyme is mediated by extracellular matrix biglycan. (Bischof AG, Yüksel D, Mammoto T, Mammoto A, Krause S, Ingber DE) Integr Biol (Camb) 2013 Aug;5(8):1045-56 PMID: 23817524 SCOPUS ID: 2-s2.0-84893450991 07/03/2013       23 Citations
  • Low urine vascular endothelial growth factor levels are associated with mechanical ventilation, bronchopulmonary dysplasia and retinopathy of prematurity. (Levesque BM, Kalish LA, Winston AB, Parad RB, Hernandez-Diaz S, Phillips M, Zolit A, Morey J, Gupta M, Mammoto A, Ingber DE, Van Marter LJ) Neonatology 2013;104(1):56-64 PMID: 23711562 SCOPUS ID: 2-s2.0-84878038265 05/29/2013       18 Citations
  • Platelet rich plasma extract promotes angiogenesis through the angiopoietin1-Tie2 pathway. (Mammoto T, Jiang A, Jiang E, Mammoto A) Microvasc Res 2013 Sep;89:15-24 PMID: 23660186 SCOPUS ID: 2-s2.0-84883172376 05/11/2013       50 Citations
  • Control of lung vascular permeability and endotoxin-induced pulmonary oedema by changes in extracellular matrix mechanics. (Mammoto A, Mammoto T, Kanapathipillai M, Wing Yung C, Jiang E, Jiang A, Lofgren K, Gee EP, Ingber DE) Nat Commun 2013;4:1759 PMID: 23612300 SCOPUS ID: 2-s2.0-84877773940 04/25/2013       67 Citations
  • Netrin-1 promotes glioblastoma cell invasiveness and angiogenesis by multiple pathways including activation of RhoA, cathepsin B, and cAMP-response element-binding protein. (Shimizu A, Nakayama H, Wang P, König C, Akino T, Sandlund J, Coma S, Italiano JE Jr, Mammoto A, Bielenberg DR, Klagsbrun M) J Biol Chem 2013 Jan 25;288(4):2210-22 PMID: 23195957 PMCID: PMC3554894 SCOPUS ID: 2-s2.0-84873813207 12/01/2012       59 Citations
  • Paxillin controls directional cell motility in response to physical cues. (Sero JE, German AE, Mammoto A, Ingber DE) Cell Adh Migr 2012 Nov-Dec;6(6):502-8 PMID: 23076140 PMCID: PMC3547894 10/19/2012    
  • LRP5 regulates development of lung microvessels and alveoli through the angiopoietin-Tie2 pathway. (Mammoto T, Chen J, Jiang E, Jiang A, Smith LE, Ingber DE, Mammoto A) PLoS One 2012;7(7):e41596 PMID: 22848540 PMCID: PMC3404972 SCOPUS ID: 2-s2.0-84864355628 08/01/2012       19 Citations
  • Mechanosensitive mechanisms in transcriptional regulation. (Mammoto A, Mammoto T, Ingber DE) J Cell Sci 2012 Jul 01;125(Pt 13):3061-73 PMID: 22797927 PMCID: PMC3434847 SCOPUS ID: 2-s2.0-84868111953 07/17/2012       245 Citations
  • Inhibition of mammary tumor growth using lysyl oxidase-targeting nanoparticles to modify extracellular matrix. (Kanapathipillai M, Mammoto A, Mammoto T, Kang JH, Jiang E, Ghosh K, Korin N, Gibbs A, Mannix R, Ingber DE) Nano Lett 2012 Jun 13;12(6):3213-7 PMID: 22554317 SCOPUS ID: 2-s2.0-84862301989 05/05/2012       62 Citations
  • A combined micromagnetic-microfluidic device for rapid capture and culture of rare circulating tumor cells. (Kang JH, Krause S, Tobin H, Mammoto A, Kanapathipillai M, Ingber DE) Lab Chip 2012 Jun 21;12(12):2175-81 PMID: 22453808 SCOPUS ID: 2-s2.0-84862234603 03/29/2012       207 Citations
  • Paxillin mediates sensing of physical cues and regulates directional cell motility by controlling lamellipodia positioning. (Sero JE, Thodeti CK, Mammoto A, Bakal C, Thomas S, Ingber DE) PLoS One 2011;6(12):e28303 PMID: 22194823 PMCID: PMC3237434 SCOPUS ID: 2-s2.0-83355173170 12/24/2011       31 Citations
  • Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. (Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnés CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, Pietramaggiori G, Scherer-Pietramaggiori SS, Short SM, Seth M, Lih FB, Tomer KB, Yang J, Schwendener RA, Hammock BD, Falck JR, Manthati VL, Ingber DE, Kaipainen A, D'Amore PA, Kieran MW, Zeldin DC) J Clin Invest 2012 Jan;122(1):178-91 PMID: 22182838 PMCID: PMC3248288 SCOPUS ID: 2-s2.0-84855453198 12/21/2011       162 Citations
  • Wnt signaling mediates pathological vascular growth in proliferative retinopathy. (Chen J, Stahl A, Krah NM, Seaward MR, Dennison RJ, Sapieha P, Hua J, Hatton CJ, Juan AM, Aderman CM, Willett KL, Guerin KI, Mammoto A, Campbell M, Smith LE) Circulation 2011 Oct 25;124(17):1871-81 PMID: 21969016 PMCID: PMC3326389 SCOPUS ID: 2-s2.0-80054993016 10/05/2011       70 Citations
  • Mechanochemical control of mesenchymal condensation and embryonic tooth organ formation. (Mammoto T, Mammoto A, Torisawa YS, Tat T, Gibbs A, Derda R, Mannix R, de Bruijn M, Yung CW, Huh D, Ingber DE) Dev Cell 2011 Oct 18;21(4):758-69 PMID: 21924961 PMCID: PMC3199351 SCOPUS ID: 2-s2.0-80054744142 09/20/2011       109 Citations
  • Multizone paper platform for 3D cell cultures. (Derda R, Tang SK, Laromaine A, Mosadegh B, Hong E, Mwangi M, Mammoto A, Ingber DE, Whitesides GM) PLoS One 2011 May 06;6(5):e18940 PMID: 21573103 PMCID: PMC3089608 SCOPUS ID: 2-s2.0-79955856918 05/17/2011       144 Citations
  • Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion. (Xu Y, Bismar TA, Su J, Xu B, Kristiansen G, Varga Z, Teng L, Ingber DE, Mammoto A, Kumar R, Alaoui-Jamali MA) J Exp Med 2010 Oct 25;207(11):2421-37 PMID: 20937704 PMCID: PMC2964581 SCOPUS ID: 2-s2.0-78149314610 10/13/2010       100 Citations
  • Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface beta1 integrins. (Matthews BD, Thodeti CK, Tytell JD, Mammoto A, Overby DR, Ingber DE) Integr Biol (Camb) 2010 Sep;2(9):435-42 PMID: 20725677 PMCID: PMC3147167 SCOPUS ID: 2-s2.0-77956329847 08/21/2010       136 Citations
  • Reconstituting organ-level lung functions on a chip. (Huh D, Matthews BD, Mammoto A, Montoya-Zavala M, Hsin HY, Ingber DE) Science 2010 Jun 25;328(5986):1662-8 PMID: 20576885 SCOPUS ID: 2-s2.0-77954038080 06/26/2010       1725 Citations
  • Paper-supported 3D cell culture for tissue-based bioassays. (Derda R, Laromaine A, Mammoto A, Tang SK, Mammoto T, Ingber DE, Whitesides GM) Proc Natl Acad Sci U S A 2009 Nov 03;106(44):18457-62 PMID: 19846768 PMCID: PMC2773961 SCOPUS ID: 2-s2.0-73249131798 10/23/2009       295 Citations
  • Cytoskeletal control of growth and cell fate switching. (Mammoto A, Ingber DE) Curr Opin Cell Biol 2009 Dec;21(6):864-70 PMID: 19740640 SCOPUS ID: 2-s2.0-70549098542 09/11/2009       159 Citations
  • Discovery of potent and practical antiangiogenic agents inspired by cortistatin A. (Czakó B, Kürti L, Mammoto A, Ingber DE, Corey EJ) J Am Chem Soc 2009 Jul 01;131(25):9014-9 PMID: 19469509 SCOPUS ID: 2-s2.0-67649576730 05/28/2009       52 Citations
  • TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling. (Thodeti CK, Matthews B, Ravi A, Mammoto A, Ghosh K, Bracha AL, Ingber DE) Circ Res 2009 May 08;104(9):1123-30 PMID: 19359599 PMCID: PMC2754067 SCOPUS ID: 2-s2.0-66149088448 04/11/2009       208 Citations
  • A mechanosensitive transcriptional mechanism that controls angiogenesis. (Mammoto A, Connor KM, Mammoto T, Yung CW, Huh D, Aderman CM, Mostoslavsky G, Smith LE, Ingber DE) Nature 2009 Feb 26;457(7233):1103-8 PMID: 19242469 PMCID: PMC2708674 SCOPUS ID: 2-s2.0-61349168351 02/27/2009       351 Citations
  • Methods for studying mechanical control of angiogenesis by the cytoskeleton and extracellular matrix. (Mammoto A, Sero JE, Mammoto T, Ingber DE) Methods Enzymol 2008;443:227-59 PMID: 18772019 SCOPUS ID: 2-s2.0-52049085563 09/06/2008       7 Citations
  • Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro. (Ghosh K, Thodeti CK, Dudley AC, Mammoto A, Klagsbrun M, Ingber DE) Proc Natl Acad Sci U S A 2008 Aug 12;105(32):11305-10 PMID: 18685096 PMCID: PMC2516246 SCOPUS ID: 2-s2.0-49649125325 08/08/2008       149 Citations
  • ABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells. (Shimizu A, Mammoto A, Italiano JE Jr, Pravda E, Dudley AC, Ingber DE, Klagsbrun M) J Biol Chem 2008 Oct 03;283(40):27230-8 PMID: 18660502 PMCID: PMC2555994 SCOPUS ID: 2-s2.0-55249110412 07/29/2008       73 Citations
  • Rho signaling and mechanical control of vascular development. (Mammoto A, Mammoto T, Ingber DE) Curr Opin Hematol 2008 May;15(3):228-34 PMID: 18391790 SCOPUS ID: 2-s2.0-41949104623 04/09/2008       50 Citations
  • Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo. (Mammoto T, Parikh SM, Mammoto A, Gallagher D, Chan B, Mostoslavsky G, Ingber DE, Sukhatme VP) J Biol Chem 2007 Aug 17;282(33):23910-8 PMID: 17562701 SCOPUS ID: 2-s2.0-34447627607 06/15/2007       125 Citations
  • The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. (Chen Z, Naveiras O, Balduini A, Mammoto A, Conti MA, Adelstein RS, Ingber D, Daley GQ, Shivdasani RA) Blood 2007 Jul 01;110(1):171-9 PMID: 17392504 PMCID: PMC1896110 SCOPUS ID: 2-s2.0-34347390082 03/30/2007       112 Citations
  • Filamin links cell shape and cytoskeletal structure to Rho regulation by controlling accumulation of p190RhoGAP in lipid rafts. (Mammoto A, Huang S, Ingber DE) J Cell Sci 2007 Feb 01;120(Pt 3):456-67 PMID: 17227794 SCOPUS ID: 2-s2.0-33847419281 01/18/2007       85 Citations
  • Role of RhoA, mDia, and ROCK in cell shape-dependent control of the Skp2-p27kip1 pathway and the G1/S transition. (Mammoto A, Huang S, Moore K, Oh P, Ingber DE) J Biol Chem 2004 Jun 18;279(25):26323-30 PMID: 15096506 SCOPUS ID: 2-s2.0-2942707853 04/21/2004       177 Citations
  • Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF. (Nanba D, Mammoto A, Hashimoto K, Higashiyama S) J Cell Biol 2003 Nov 10;163(3):489-502 PMID: 14597771 PMCID: PMC2173632 SCOPUS ID: 2-s2.0-0242425875 11/05/2003       134 Citations
  • Intravenous anesthetic, propofol inhibits invasion of cancer cells. (Mammoto T, Mukai M, Mammoto A, Yamanaka Y, Hayashi Y, Mashimo T, Kishi Y, Nakamura H) Cancer Lett 2002 Oct 28;184(2):165-70 PMID: 12127688 SCOPUS ID: 2-s2.0-0037190808 07/20/2002       117 Citations
  • Infiltration anesthetic lidocaine inhibits cancer cell invasion by modulating ectodomain shedding of heparin-binding epidermal growth factor-like growth factor (HB-EGF). (Mammoto T, Higashiyama S, Mukai M, Mammoto A, Ayaki M, Mashimo T, Hayashi Y, Kishi Y, Nakamura H, Akedo H) J Cell Physiol 2002 Sep;192(3):351-8 PMID: 12124780 SCOPUS ID: 2-s2.0-0036321571 07/19/2002       38 Citations
  • Stimulation of Rho GDI release by ERM proteins. (Mammoto A, Takahashi K, Sasaki T, Takai Y) Methods Enzymol 2000;325:91-101 PMID: 11036595 SCOPUS ID: 2-s2.0-0033780416 10/19/2000       11 Citations
  • Rho small G-protein-dependent binding of mDia to an Src homology 3 domain-containing IRSp53/BAIAP2. (Fujiwara T, Mammoto A, Kim Y, Takai Y) Biochem Biophys Res Commun 2000 May 19;271(3):626-9 PMID: 10814512 SCOPUS ID: 2-s2.0-0034685631 05/18/2000       67 Citations
  • Physical and functional interaction of rabphilin-11 with mammalian Sec13 protein. Implication in vesicle trafficking. (Mammoto A, Sasaki T, Kim Y, Takai Y) J Biol Chem 2000 May 05;275(18):13167-70 PMID: 10747849 SCOPUS ID: 2-s2.0-0034607642 04/05/2000       16 Citations
  • Rab11BP/Rabphilin-11, a downstream target of rab11 small G protein implicated in vesicle recycling. (Mammoto A, Ohtsuka T, Hotta I, Sasaki T, Takai Y) J Biol Chem 1999 Sep 03;274(36):25517-24 PMID: 10464283 SCOPUS ID: 2-s2.0-0033520460 08/28/1999       78 Citations
  • Distinct actions and cooperative roles of ROCK and mDia in Rho small G protein-induced reorganization of the actin cytoskeleton in Madin-Darby canine kidney cells. (Nakano K, Takaishi K, Kodama A, Mammoto A, Shiozaki H, Monden M, Takai Y) Mol Biol Cell 1999 Aug;10(8):2481-91 PMID: 10436006 PMCID: PMC25478 SCOPUS ID: 2-s2.0-0032784388 08/06/1999       136 Citations
  • Interaction of radixin with Rho small G protein GDP/GTP exchange protein Dbl. (Takahashi K, Sasaki T, Mammoto A, Hotta I, Takaishi K, Imamura H, Nakano K, Kodama A, Takai Y) Oncogene 1998 Jun 25;16(25):3279-84 PMID: 9681826 SCOPUS ID: 2-s2.0-0032566011 07/29/1998       98 Citations
  • Interactions of drebrin and gephyrin with profilin. (Mammoto A, Sasaki T, Asakura T, Hotta I, Imamura H, Takahashi K, Matsuura Y, Shirao T, Takai Y) Biochem Biophys Res Commun 1998 Feb 04;243(1):86-9 PMID: 9473484 SCOPUS ID: 2-s2.0-0032481298 02/25/1998       120 Citations
  • Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein. (Takahashi K, Sasaki T, Mammoto A, Takaishi K, Kameyama T, Tsukita S, Takai Y) J Biol Chem 1997 Sep 12;272(37):23371-5 PMID: 9287351 SCOPUS ID: 2-s2.0-0030846295 09/12/1997       347 Citations
  • Involvement of a sperm protein sensitive to sulfhydryl-depleting reagents in mouse sperm-egg fusion. (Mammoto A, Masumoto N, Tahara M, Yoneda M, Nishizaki T, Tasaka K, Miyake A) J Exp Zool 1997 Jun 15;278(3):178-88 PMID: 9181696 SCOPUS ID: 2-s2.0-0031570766 06/15/1997       13 Citations
  • Involvement of Rabphilin-3A in cortical granule exocytosis in mouse eggs. (Masumoto N, Sasaki T, Tahara M, Mammoto A, Ikebuchi Y, Tasaka K, Tokunaga M, Takai Y, Miyake A) J Cell Biol 1996 Dec;135(6 Pt 2):1741-7 PMID: 8991087 PMCID: PMC2133937 SCOPUS ID: 2-s2.0-0030461545 12/01/1996       38 Citations
  • Reactive oxygen species block sperm-egg fusion via oxidation of sperm sulfhydryl proteins in mice. (Mammoto A, Masumoto N, Tahara M, Ikebuchi Y, Ohmichi M, Tasaka K, Miyake A) Biol Reprod 1996 Nov;55(5):1063-8 PMID: 8902218 SCOPUS ID: 2-s2.0-0029908454 11/01/1996       47 Citations
  • Dynamics of cortical granule exocytosis at fertilization in living mouse eggs. (Tahara M, Tasaka K, Masumoto N, Mammoto A, Ikebuchi Y, Miyake A) Am J Physiol 1996 May;270(5 Pt 1):C1354-61 PMID: 8967435 SCOPUS ID: 2-s2.0-0030008499 05/01/1996       45 Citations
  • Inhibition of mouse placental lactogen-II release from placental cells by interleukin-1 after mid-pregnancy. (Yamaguchi M, Sakata M, Ogura K, Adachi K, Mammoto A, Miyake A) J Endocrinol 1995 Dec;147(3):423-9 PMID: 8543912 SCOPUS ID: 2-s2.0-0028834308 12/01/1995       3 Citations
  • Regulation of mouse soluble interleukin-6 receptor secretion by decidua. (Yamaguchi M, Mammoto A, Taga T, Kishimoto T, Miyake A) Biochem Biophys Res Commun 1995 Jun 26;211(3):1077-82 PMID: 7598695 SCOPUS ID: 2-s2.0-0029010178 06/26/1995       6 Citations
  • Scanning electron microscope assessment of exocytotic changes in purified gonadotropes. (Mizuki J, Masumoto N, Tahara M, Fukami K, Mammoto A, Tasaka K, Miyake A) J Endocrinol 1995 Feb;144(2):193-200 PMID: 7706972 SCOPUS ID: 2-s2.0-0028955663 02/01/1995       2 Citations
  • Last update: 08/23/2020
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