Medical College of Wisconsin
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Amy Rymaszewski PhD

Amy Rymaszewski PhD profile photo picture

Research Scientist I

Institution: Medical College of Wisconsin
Department: Pediatrics
Division: Allergy

Research Areas of Interest

  • Adaptive Immunity
  • Allergy and Immunology
  • Autoimmune Lymphoproliferative Syndrome
  • Common Variable Immunodeficiency
  • Immune Complex Diseases
  • Immune System
  • Immune System Diseases
  • Immunogenetics
  • Immunologic Techniques
  • Immunophenotyping
  • Immunoproliferative Disorders
  • Severe Combined Immunodeficiency
  • immunology

    • Research Experience

  • Flow Cytometry
  • Genetics, Medical
  • Human Genetics
  • Immunogenetics
  • Immunophenotyping

    • Publications (13)

  • Dysregulated Lymphocyte Antigen Receptor Signaling in Common Variable Immunodeficiency with Granulomatous Lymphocytic Interstitial Lung Disease. (Lui VG, Ghosh T, Rymaszewski A, Chen S, Baxter RM, Kong DS, Ghosh D, Routes JM, Verbsky JW, Hsieh EWY) J Clin Immunol 2023 Aug;43(6):1311-1325 PMID: 37093407 PMCID: PMC10524976 SCOPUS ID: 2-s2.0-85153408410 04/24/2023    
  • Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients. (Le Coz C, Nguyen DN, Su C, Nolan BE, Albrecht AV, Xhani S, Sun D, Demaree B, Pillarisetti P, Khanna C, Wright F, Chen PA, Yoon S, Stiegler AL, Maurer K, Garifallou JP, Rymaszewski A, Kroft SH, Olson TS, Seif AE, Wertheim G, Grant SFA, Vo LT, Puck JM, Sullivan KE, Routes JM, Zakharova V, Shcherbina A, Mukhina A, Rudy NL, Hurst ACE, Atkinson TP, Boggon TJ, Hakonarson H, Abate AR, Hajjar J, Nicholas SK, Lupski JR, Verbsky J, Chinn IK, Gonzalez MV, Wells AD, Marson A, Poon GMK, Romberg N) J Exp Med 2021 Jul 05;218(7) PMID: 33951726 PMCID: PMC8105723 SCOPUS ID: 2-s2.0-85105296806 05/06/2021       15 Citations
  • Rituximab and antimetabolite treatment of granulomatous and lymphocytic interstitial lung disease in common variable immunodeficiency. (Verbsky JW, Hintermeyer MK, Simpson PM, Feng M, Barbeau J, Rao N, Cool CD, Sosa-Lozano LA, Baruah D, Hammelev E, Busalacchi A, Rymaszewski A, Woodliff J, Chen S, Bausch-Jurken M, Routes JM) J Allergy Clin Immunol 2021 Feb;147(2):704-712.e17 PMID: 32745555 SCOPUS ID: 2-s2.0-85089870161 08/04/2020       26 Citations
  • Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome. (Yang C, Siebert JR, Burns R, Gerbec ZJ, Bonacci B, Rymaszewski A, Rau M, Riese MJ, Rao S, Carlson KS, Routes JM, Verbsky JW, Thakar MS, Malarkannan S) Nat Commun 2019 Sep 02;10(1):3931 PMID: 31477722 PMCID: PMC6718415 SCOPUS ID: 2-s2.0-85071610251 09/04/2019       125 Citations
  • Damaging BTK Variant Demonstrated by Carrier, Allele-Specific BTK Expression in B Cells and Monocytes. (Bausch-Jurken MT, Hintermeyer M, Woodliff J, Chen S, Rymaszewski A, Verbsky J, Routes J) J Clin Immunol 2019 Jan;39(1):23-25 PMID: 30627929 SCOPUS ID: 2-s2.0-85059675420 01/11/2019    
  • The tumor-suppressive small GTPase DiRas1 binds the noncanonical guanine nucleotide exchange factor SmgGDS and antagonizes SmgGDS interactions with oncogenic small GTPases. (Bergom C, Hauser AD, Rymaszewski A, Gonyo P, Prokop JW, Jennings BC, Lawton AJ, Frei A, Lorimer EL, Aguilera-Barrantes I, Mackinnon AC Jr, Noon K, Fierke CA, Williams CL) J Biol Chem 2016 May 13;291(20):10948 PMID: 27197236 PMCID: PMC4865938 05/20/2016    
  • The Tumor-suppressive Small GTPase DiRas1 Binds the Noncanonical Guanine Nucleotide Exchange Factor SmgGDS and Antagonizes SmgGDS Interactions with Oncogenic Small GTPases. (Bergom C, Hauser AD, Rymaszewski A, Gonyo P, Prokop JW, Jennings BC, Lawton AJ, Frei A, Lorimer EL, Aguilera-Barrantes I, Mackinnon AC, Noon K, Fierke CA, Williams CL) J Biol Chem 2016 Mar 18;291(12):6534-45 PMID: 26814130 PMCID: PMC4813585 SCOPUS ID: 2-s2.0-84964859354 01/28/2016       22 Citations
  • The role of neutrophil myeloperoxidase in models of lung tumor development. (Rymaszewski AL, Tate E, Yimbesalu JP, Gelman AE, Jarzembowski JA, Zhang H, Pritchard KA Jr, Vikis HG) Cancers (Basel) 2014 May 09;6(2):1111-27 PMID: 24821130 PMCID: PMC4074819 SCOPUS ID: 2-s2.0-84901207748 05/14/2014       70 Citations
  • CRR9/CLPTM1L regulates cell survival signaling and is required for Ras transformation and lung tumorigenesis. (James MA, Vikis HG, Tate E, Rymaszewski AL, You M) Cancer Res 2014 Feb 15;74(4):1116-27 PMID: 24366883 PMCID: PMC6005686 SCOPUS ID: 2-s2.0-84894226710 12/25/2013       51 Citations
  • Mouse models of chemically-induced lung carcinogenesis. (Vikis HG, Rymaszewski AL, Tichelaar JW) Front Biosci (Elite Ed) 2013 Jun 01;5(3):939-46 PMID: 23747909 SCOPUS ID: 2-s2.0-84884318689 06/12/2013       20 Citations
  • Signaling through L-selectin mediates enhanced chemotaxis of lymphocyte subsets to secondary lymphoid tissue chemokine. (Subramanian H, Grailer JJ, Ohlrich KC, Rymaszewski AL, Loppnow JJ, Kodera M, Conway RM, Steeber DA) J Immunol 2012 Apr 01;188(7):3223-36 PMID: 22387549 SCOPUS ID: 2-s2.0-84859393303 03/06/2012       34 Citations
  • Neutrophils are required for 3-methylcholanthrene-initiated, butylated hydroxytoluene-promoted lung carcinogenesis. (Vikis HG, Gelman AE, Franklin A, Stein L, Rymaszewski A, Zhu J, Liu P, Tichelaar JW, Krupnick AS, You M) Mol Carcinog 2012 Dec;51(12):993-1002 PMID: 22006501 PMCID: PMC3389580 SCOPUS ID: 2-s2.0-84867746013 10/19/2011       20 Citations
  • The SPOROCYTELESS/NOZZLE gene is involved in controlling stamen identity in Arabidopsis. (Liu X, Huang J, Parameswaran S, Ito T, Seubert B, Auer M, Rymaszewski A, Jia G, Owen HA, Zhao D) Plant Physiol 2009 Nov;151(3):1401-11 PMID: 19726570 PMCID: PMC2773108 SCOPUS ID: 2-s2.0-70350680812 09/04/2009       66 Citations
    • Last update: 04/25/2023