Medical College of Wisconsin
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Chien-Wei Lin PhD

Chien-Wei Lin PhD profile photo picture

Assistant Professor

Institution: Medical College of Wisconsin
Department: Institute for Health and Equity
Division: Biostatistics
Program: Research

Member of the Genomic Sciences and Precision Medicine Center (GSPMC)

View Curriculum Vitae

Publications (32)

  • Dysregulated Free Fatty Acid Receptor 2 Exacerbates Colonic Adenoma Formation in Apc Min/+ Mice: Relation to Metabolism and Gut Microbiota Composition. (Huang YW, Lin CW, Pan P, Echeveste CE, Dong A, Oshima K, Yearsley M, Yu J, Wang LS) J Cancer Prev 2021 Mar 30;26(1):32-40 PMID: 33842404 PMCID: PMC8020170 04/13/2021    
  • Simultaneous estimation of cluster number and feature sparsity in high-dimensional cluster analysis. (Li Y, Zeng X, Lin CW, Tseng GC) Biometrics 2021 Feb 23 PMID: 33621349 02/24/2021    
  • Targeting PIM1-Mediated Metabolism in Myeloid Suppressor Cells to Treat Cancer. (Xin G, Chen Y, Topchyan P, Kasmani MY, Burns R, Volberding PJ, Wu X, Cohn A, Chen Y, Lin CW, Ho PC, Silverstein R, Dwinell MB, Cui W) Cancer Immunol Res 2021 Feb 12 PMID: 33579728 02/14/2021    
  • Black Raspberries Suppress Colorectal Cancer by Enhancing Smad4 Expression in Colonic Epithelium and Natural Killer Cells. (Huang YW, Lin CW, Pan P, Shan T, Echeveste CE, Mo YY, Wang HT, Aldakkak M, Tsai S, Oshima K, Yearsley M, Xiao J, Cao H, Sun C, Du M, Bai W, Yu J, Wang LS) Front Immunol 2020;11:570683 PMID: 33424832 PMCID: PMC7793748 SCOPUS ID: 2-s2.0-85098236353 01/12/2021    
  • Single-cell lineage mapping of a diverse virus-specific naive CD4 T cell repertoire. (Khatun A, Kasmani MY, Zander R, Schauder DM, Snook JP, Shen J, Wu X, Burns R, Chen YG, Lin CW, Williams MA, Cui W) J Exp Med 2021 Mar 01;218(3) PMID: 33201171 PMCID: PMC7676493 SCOPUS ID: 2-s2.0-85096353007 11/18/2020    
  • Duchenne muscular dystrophy (DMD) cardiomyocyte-secreted exosomes promote the pathogenesis of DMD-associated cardiomyopathy. (Gartz M, Lin CW, Sussman MA, Lawlor MW, Strande JL) Dis Model Mech 2020 11 13;13(11) PMID: 33188007 PMCID: PMC7673361 SCOPUS ID: 2-s2.0-85096154674 11/15/2020       2 Citations
  • Older molecular brain age in severe mental illness. (Lin CW, Chang LC, Ma T, Oh H, French B, Puralewski R, Mathews F, Fang Y, Lewis DA, Kennedy JL, Mueller D, Marshe VS, Jaffe A, Chen Q, Ursini G, Weinberger D, Newman AB, Lenze EJ, Nikolova YS, Tseng GC, Sibille E) Mol Psychiatry 2020 Jul 06 PMID: 32632206 PMCID: PMC7785531 07/08/2020    
  • Comparative Pathway Integrator: A Framework of Meta-Analytic Integration of Multiple Transcriptomic Studies for Consensual and Differential Pathway Analysis. (Zeng X, Zong W, Lin CW, Fang Z, Ma T, Lewis DA, Enwright JF, Tseng GC) Genes (Basel) 2020 06 24;11(6) PMID: 32599927 PMCID: PMC7348908 07/01/2020       1 Citation
  • Black raspberries suppress pancreatic cancer through modulation of NKp46+, CD8+, and CD11b+ immune cells. (Pan P, Zhu Z, Oshima K, Aldakkak M, Tsai S, Huang YW, Dong W, Zhang J, Lin CW, Wang Y, Yearsley M, Yu J, Wang LS) Food Front 2020 Mar;1(1):70-82 PMID: 32368735 PMCID: PMC7197210 05/06/2020    
  • Mortalin (HSPA9) facilitates BRAF-mutant tumor cell survival by suppressing ANT3-mediated mitochondrial membrane permeability. (Wu PK, Hong SK, Chen W, Becker AE, Gundry RL, Lin CW, Shao H, Gestwicki JE, Park JI) Sci Signal 2020 03 10;13(622) PMID: 32156782 PMCID: PMC7099430 SCOPUS ID: 2-s2.0-85081677231 03/12/2020       6 Citations
  • Novel KLHL26 variant associated with a familial case of Ebstein's anomaly and left ventricular noncompaction. (Samudrala SSK, North LM, Stamm KD, Earing MG, Frommelt MA, Willes R, Tripathi S, Dsouza NR, Zimmermann MT, Mahnke DK, Liang HL, Lund M, Lin CW, Geddes GC, Mitchell ME, Tomita-Mitchell A) Mol Genet Genomic Med 2020 04;8(4):e1152 PMID: 31985165 PMCID: PMC7196453 SCOPUS ID: 2-s2.0-85078673520 01/28/2020       1 Citation
  • MethylSeqDesign: a framework for Methyl-Seq genome-wide power calculation and study design issues. (Liu P, Lin CW, Park Y, Tseng G) Biostatistics 2021 Jan 28;22(1):35-50 PMID: 31107532 PMCID: PMC7846147 05/21/2019       1 Citation
  • RNASeqDesign: A framework for RNA-Seq genome-wide power calculation and study design issues. (Lin CW, Liao SG, Liu P, Park YS, Lee MT, Tseng GC) J R Stat Soc Ser C Appl Stat 2019 Apr;68(3):683-704 PMID: 33692596 PMCID: PMC7941184 04/01/2019    
  • DNA methylation in the human frontal cortex reveals a putative mechanism for age-by-disease interactions. (McKinney BC, Lin CW, Rahman T, Oh H, Lewis DA, Tseng G, Sibille E) Transl Psychiatry 2019 01 29;9(1):39 PMID: 30696804 PMCID: PMC6351569 01/31/2019       4 Citations
  • RNASeqDesign: a framework for ribonucleic acid sequencing genomewide power calculation and study design issues (Chien-Wei Lin, Serena G. Liao, Peng Liu, Mei‐Ling Ting Lee, Yong Seok Park, George C. Tseng) Journal of the Royal Statistical Society. Series C, Applied statistics 12/09/2018    
  • MetaOmics: analysis pipeline and browser-based software suite for transcriptomic meta-analysis. (Ma T, Huo Z, Kuo A, Zhu L, Fang Z, Zeng X, Lin CW, Liu S, Wang L, Liu P, Rahman T, Chang LC, Kim S, Li J, Park Y, Song C, Oesterreich S, Sibille E, Tseng GC) Bioinformatics 2019 05 01;35(9):1597-1599 PMID: 30304367 PMCID: PMC6499246 10/12/2018       8 Citations
  • Temporal and Spatial Post-Transcriptional Regulation of Zebrafish tie1 mRNA by Long Noncoding RNA During Brain Vascular Assembly. (Chowdhury TA, Koceja C, Eisa-Beygi S, Kleinstiver BP, Kumar SN, Lin CW, Li K, Prabhudesai S, Joung JK, Ramchandran R) Arterioscler Thromb Vasc Biol 2018 07;38(7):1562-1575 PMID: 29724820 PMCID: PMC6023729 05/05/2018       7 Citations
  • Enhanced Molecular Aging in Late-Life Depression: the Senescent-Associated Secretory Phenotype. (Diniz BS, Reynolds CF 3rd, Sibille E, Lin CW, Tseng G, Lotrich F, Aizenstein HJ, Butters MA) Am J Geriatr Psychiatry 2017 01;25(1):64-72 PMID: 27856124 PMCID: PMC5164865 11/20/2016       25 Citations
  • Age-dependent increase in Kalirin-9 and Kalirin-12 transcripts in human orbitofrontal cortex. (Grubisha MJ, Lin CW, Tseng GC, Penzes P, Sibille E, Sweet RA) Eur J Neurosci 2016 10;44(7):2483-2492 PMID: 27471199 PMCID: PMC5048532 07/30/2016       3 Citations
  • Circulating biosignatures of late-life depression (LLD): Towards a comprehensive, data-driven approach to understanding LLD pathophysiology. (Diniz BS, Lin CW, Sibille E, Tseng G, Lotrich F, Aizenstein HJ, Reynolds CF, Butters MA) J Psychiatr Res 2016 11;82:1-7 PMID: 27447786 07/23/2016       23 Citations
  • Predisposition to treatment response in major depressive episode: A peripheral blood gene coexpression network analysis. (Belzeaux R, Lin CW, Ding Y, Bergon A, Ibrahim EC, Turecki G, Tseng G, Sibille E) J Psychiatr Res 2016 10;81:119-26 PMID: 27438688 07/21/2016       17 Citations
  • SMART: Statistical Metabolomics Analysis-An R Tool. (Liang YJ, Lin YT, Chen CW, Lin CW, Chao KM, Pan WH, Yang HC) Anal Chem 2016 06 21;88(12):6334-41 PMID: 27248514 06/02/2016       15 Citations
  • MetaKTSP: a meta-analytic top scoring pair method for robust cross-study validation of omics prediction analysis. (Kim S, Lin CW, Tseng GC) Bioinformatics 2016 07 01;32(13):1966-73 PMID: 27153719 PMCID: PMC6280887 05/07/2016       16 Citations
  • FRAS1-related extracellular matrix 3 (FREM3) single-nucleotide polymorphism effects on gene expression, amygdala reactivity and perceptual processing speed: An accelerated aging pathway of depression risk. (Nikolova YS, Iruku SP, Lin CW, Conley ED, Puralewski R, French B, Hariri AR, Sibille E) Front Psychol 2015;6:1377 PMID: 26441752 PMCID: PMC4584966 10/07/2015    
  • Hypermethylation of BDNF and SST Genes in the Orbital Frontal Cortex of Older Individuals: A Putative Mechanism for Declining Gene Expression with Age. (McKinney BC, Lin CW, Oh H, Tseng GC, Lewis DA, Sibille E) Neuropsychopharmacology 2015 Oct;40(11):2604-13 PMID: 25881116 PMCID: PMC4569950 04/17/2015       19 Citations
  • VSNL1 Co-Expression Networks in Aging Include Calcium Signaling, Synaptic Plasticity, and Alzheimer's Disease Pathways. (Lin CW, Chang LC, Tseng GC, Kirkwood CM, Sibille EL, Sweet RA) Front Psychiatry 2015;6:30 PMID: 25806004 PMCID: PMC4353182 03/26/2015    
  • Applying genome-wide gene-based expression quantitative trait locus mapping to study population ancestry and pharmacogenetics. (Yang HC, Lin CW, Chen CW, Chen JJ) BMC Genomics 2014 Apr 29;15:319 PMID: 24779372 PMCID: PMC4236814 05/02/2014       6 Citations
  • A conserved BDNF, glutamate- and GABA-enriched gene module related to human depression identified by coexpression meta-analysis and DNA variant genome-wide association studies. (Chang LC, Jamain S, Lin CW, Rujescu D, Tseng GC, Sibille E) PLoS One 2014;9(3):e90980 PMID: 24608543 PMCID: PMC3946570 03/13/2014       50 Citations
  • An analytical model for generalized ESP games (Wang, B. C., Lin, C. W., Chen, K. T., & Chen, L. J. ) Knowledge-based systems 10/01/2012    
  • Integrative analysis of single nucleotide polymorphisms and gene expression efficiently distinguishes samples from closely related ethnic populations. (Yang HC, Wang PL, Lin CW, Chen CH, Chen CH) BMC Genomics 2012 Jul 28;13:346 PMID: 22839760 PMCID: PMC3453505 07/31/2012       9 Citations
  • SAQC: SNP array quality control. (Yang HC, Lin HC, Kang M, Chen CH, Lin CW, Li LH, Wu JY, Chen YT, Pan WH) BMC Bioinformatics 2011 Apr 18;12:100 PMID: 21501472 PMCID: PMC3101186 04/20/2011       4 Citations
  • A goodness-of-fit test for Archimedean copula models in the presence of right censoring (Emura, T., Lin, C. W., & Wang, W.) Computational Statistics and Data Analysis 04/02/2010    
    • Last update: 04/16/2021