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Medical College of Wisconsin

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Hartmut Weiler PhD

Associate Professor

Institution: Medical College of Wisconsin
Department: Physiology
Program: Genetics

Member of the Cardiovascular Center
Member of the Center for Immunology

I am willing to collaborate on research projects.
I am willing to mentor a junior faculty member.

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Publications (117)

TF-FVIIa PAR2-β-Arrestin Signaling Sustains Organ Dysfunction in Coxsackievirus B3 Infection of Mice. (Kespohl M, Goetzke CC, Althof N, Bredow C, Kelm N, Pinkert S, Bukur T, Bukur V, Grunz K, Kaur D, Heuser A, Mülleder M, Sauter M, Klingel K, Weiler H, Berndt N, Gaida MM, Ruf W, Beling A) Arterioscler Thromb Vasc Biol 2024 Apr;44(4):843-865 PMID: 38385286 SCOPUS ID: 2-s2.0-85188941808 02/22/2024

Endothelial Protein C Receptor and 3K3A-Activated Protein C Protect Mice from Allergic Contact Dermatitis in a Contact Hypersensitivity Model. (Xue M, Jackson CJ, Lin H, Zhao R, Liang HPH, Weiler H, Griffin JH, March L) Int J Mol Sci 2024 Jan 19;25(2) PMID: 38279255 PMCID: PMC10816322 SCOPUS ID: 2-s2.0-85183394244 01/27/2024

A recombinant signalling-selective activated protein C that lacks anticoagulant activity is efficacious and safe in cutaneous wound preclinical models. (Zhao R, Xue M, Lin H, Smith M, Liang H, Weiler H, Griffin JH, Jackson CJ) Wound Repair Regen 2024;32(1):90-103 PMID: 38155595 SCOPUS ID: 2-s2.0-85181236662 12/29/2023

Nucleic acid sensing promotes inflammatory monocyte migration through biased coagulation factor VIIa signaling. (Zelaya H, Grunz K, Nguyen TS, Habibi A, Witzler C, Reyda S, Gonzalez-Menendez I, Quintanilla-Martinez L, Bosmann M, Weiler H, Ruf W) Blood 2024 Mar 07;143(10):845-857 PMID: 38096370 PMCID: PMC10940062 SCOPUS ID: 2-s2.0-85183567201 12/14/2023 3 Citations

EPCR deficiency ameliorates inflammatory arthritis in mice by suppressing the activation and migration of T cells and dendritic cells. (Xue M, Lin H, Liang HPH, Bereza-Malcolm L, Lynch T, Sinnathurai P, Weiler H, Jackson C, March L) Rheumatology (Oxford) 2024 Feb 01;63(2):571-580 PMID: 37228024 PMCID: PMC10834933 SCOPUS ID: 2-s2.0-85184021231 05/25/2023 1 Citation

Platelet tissue factor pathway inhibitor-α dampens cardiac thrombosis and associated fibrosis in mice. (Maroney SA, Siebert AE, Martinez ND, Rasmussen M, Peterson JA, Weiler H, Lincoln J, Mast AE) J Thromb Haemost 2023 Mar;21(3):639-651 PMID: 36696221 PMCID: PMC10200073 SCOPUS ID: 2-s2.0-85149182853 01/26/2023 2 Citations

Ristocetin dependent cofactor activity in von Willebrand disease diagnosis: Limitations of relying on a single measure. (Christopherson PA, Haberichter SL, Flood VH, Sicking UO, Abshire TC, Montgomery RR, Zimmerman Program Investigators) Res Pract Thromb Haemost 2022 Oct;6(7):e12807 PMID: 36381287 PMCID: PMC9637542 SCOPUS ID: 2-s2.0-85142096764 11/17/2022 3 Citations

Protease- and cell type-specific activation of protease-activated receptor 2 in cutaneous inflammation. (Fleischer MI, Röhrig N, Raker VK, Springer J, Becker D, Ritz S, Bros M, Stege H, Haist M, Grabbe S, Haub J, Becker C, Reyda S, Disse J, Schmidt T, Mahnke K, Weiler H, Ruf W, Steinbrink K) J Thromb Haemost 2022 Dec;20(12):2823-2836 PMID: 36161697 SCOPUS ID: 2-s2.0-85140121210 09/27/2022 4 Citations

Blocking hemophilic arthropathy. (Shi Q, Weiler H) Blood 2022 May 05;139(18):2734-2735 PMID: 35511191 SCOPUS ID: 2-s2.0-85129525401 05/06/2022 1 Citation

Coagulation Factor IIIa (f3a) Knockdown in Zebrafish Leads to Defective Angiogenesis and Mild Bleeding Phenotype. (Subramaniam S, Liu J, Fletcher C, Ramchandran R, Weiler H) Front Cell Dev Biol 2022;10:852989 PMID: 35386206 PMCID: PMC8978257 SCOPUS ID: 2-s2.0-85128081688 04/08/2022 1 Citation

The impact of aberrant von Willebrand factor-GPIbα interaction on megakaryopoiesis and platelets in humanized type 2B von Willebrand disease model mouse. (Kanaji S, Morodomi Y, Weiler H, Zarpellon A, Montgomery RR, Ruggeri ZM, Kanaji T) Haematologica 2022 Sep 01;107(9):2133-2143 PMID: 35142156 PMCID: PMC9425322 SCOPUS ID: 2-s2.0-85131561060 02/11/2022 1 Citation

A novel mouse model of type 2N VWD was developed by CRISPR/Cas9 gene editing and recapitulates human type 2N VWD. (Shi Q, Fahs SA, Mattson JG, Yu H, Perry CL, Morateck PA, Schroeder JA, Rapten J, Weiler H, Montgomery RR) Blood Adv 2022 May 10;6(9):2778-2790 PMID: 35015821 PMCID: PMC9092403 SCOPUS ID: 2-s2.0-85130105632 01/12/2022 2 Citations

Bleeding diathesis in mice lacking JAK2 in platelets (Eaton N, Subramaniam S, Schulte ML, Drew C, Jakab D, Haberichter SL, Weiler H, Falet H) Blood Advances 10 August 2021;5(15):2969-2981 SCOPUS ID: 2-s2.0-85112565305 08/10/2021 6 Citations

Bleeding diathesis in mice lacking JAK2 in platelets. (Eaton N, Subramaniam S, Schulte ML, Drew C, Jakab D, Haberichter SL, Weiler H, Falet H) Blood Adv 2021 Aug 10;5(15):2969-2981 PMID: 34342643 PMCID: PMC8361459 08/04/2021

Thromboelastometry assessment of hemostatic properties in various murine models with coagulopathy and the effect of factor VIII therapeutics. (Schroeder JA, Kuether EA, Fang J, Jing W, Weiler H, Wilcox DA, Montgomery RR, Shi Q) J Thromb Haemost 2021 Oct;19(10):2417-2427 PMID: 34245090 PMCID: PMC8865566 SCOPUS ID: 2-s2.0-85111140299 07/11/2021 4 Citations

A thrombin-PAR1/2 feedback loop amplifies thromboinflammatory endothelial responses to the viral RNA analogue poly(I:C). (Subramaniam S, Ogoti Y, Hernandez I, Zogg M, Botros F, Burns R, DeRousse JT, Dockendorff C, Mackman N, Antoniak S, Fletcher C, Weiler H) Blood Adv 2021 Jul 13;5(13):2760-2774 PMID: 34242391 PMCID: PMC8288670 SCOPUS ID: 2-s2.0-85110116594 07/10/2021 12 Citations

Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin. (Sridharan V, Johnson KA, Landes RD, Cao M, Singh P, Wagoner G, Hayar A, Sprick ED, Eveld KA, Bhattacharyya A, Krager KJ, Aykin-Burns N, Weiler H, Fernández JA, Griffin JH, Boerma M) PLoS One 2021;16(5):e0252142 PMID: 34029348 PMCID: PMC8143413 SCOPUS ID: 2-s2.0-85106514258 05/25/2021 9 Citations

Thrombomodulin is essential for maintaining quiescence in vascular endothelial cells. (Giri H, Panicker SR, Cai X, Biswas I, Weiler H, Rezaie AR) Proc Natl Acad Sci U S A 2021 Mar 16;118(11) PMID: 33836597 PMCID: PMC7980409 SCOPUS ID: 2-s2.0-85102375682 04/11/2021 29 Citations

Synthesis and initial pharmacology of dual-targeting ligands for putative complexes of integrin αVβ3 and PAR2. (Majewski MW, Gandhi DM, Holyst T, Wang Z, Hernandez I, Rosas R Jr, Zhu J, Weiler H, Dockendorff C) RSC Med Chem 2020 Aug 01;11(8):940-949 PMID: 33479689 PMCID: PMC7496306 SCOPUS ID: 2-s2.0-85091019890 01/23/2021 2 Citations

Macrophage protease-activated receptor 2 regulates fetal liver erythropoiesis in mice. (Saffarzadeh M, Grunz K, Nguyen TS, Lee YK, Kitano M, Danckwardt S, Rodrigues CDS, Weiler H, Reyda S, Ruf W) Blood Adv 2020 Nov 24;4(22):5810-5824 PMID: 33232477 PMCID: PMC7686899 SCOPUS ID: 2-s2.0-85097247813 11/25/2020 8 Citations

Tissue factor pathway inhibitor is required for cerebrovascular development in mice. (Maroney SA, Westrick RJ, Cleuren AC, Martinez ND, Siebert AE, Zogg M, Ginsburg D, Weiler H, Mast AE) Blood 2021 Jan 14;137(2):258-268 PMID: 32735640 PMCID: PMC7820871 SCOPUS ID: 2-s2.0-85099956667 08/01/2020 10 Citations

Synthesis and initial pharmacology of dual-targeting ligands for putative complexes of integrin αvβ3 and PAR2 (Majewski MW, Gandhi DM, Holyst T, Wang Z, Hernandez I, Rosas R, Zhu J, Weiler H, Dockendorff C) RSC Medicinal Chemistry August 2020;11(8):940-949 SCOPUS ID: 2-s2.0-85091019890 08/01/2020 2 Citations

A rat model of severe VWD by elimination of the VWF gene using CRISPR/Cas9. (Garcia J, Flood VH, Haberichter SL, Fahs SA, Mattson JG, Geurts AM, Zogg M, Weiler H, Shi Q, Montgomery RR) Res Pract Thromb Haemost 2020 Jan;4(1):64-71 PMID: 31989086 PMCID: PMC6971331 SCOPUS ID: 2-s2.0-85105291983 01/29/2020 2 Citations

The severe spontaneous bleeding phenotype in a novel hemophilia A rat model is rescued by platelet FVIII expression. (Shi Q, Mattson JG, Fahs SA, Geurts AM, Weiler H, Montgomery RR) Blood Adv 2020 Jan 14;4(1):55-65 PMID: 31899798 PMCID: PMC6960468 SCOPUS ID: 2-s2.0-85078174834 01/04/2020 11 Citations

The Adult Murine Intestine is Dependent on Constitutive Laminin-γ1 Synthesis. (Fields B, DeLaForest A, Zogg M, May J, Hagen C, Komnick K, Wieser J, Lundberg A, Weiler H, Battle MA, Carlson KS) Sci Rep 2019 Dec 17;9(1):19303 PMID: 31848396 PMCID: PMC6917708 SCOPUS ID: 2-s2.0-85076615345 12/19/2019 6 Citations

Role of thrombomodulin expression on hematopoietic stem cells. (Basu S, Liang HPH, Hernandez I, Zogg M, Fields B, May J, Ogoti Y, Wyseure T, Mosnier LO, Burns RT, Carlson K, Weiler H) J Thromb Haemost 2020 Jan;18(1):123-135 PMID: 31628891 PMCID: PMC6940513 SCOPUS ID: 2-s2.0-85074837812 10/20/2019 3 Citations

Myeloid cell-synthesized coagulation factor X dampens antitumor immunity. (Graf C, Wilgenbus P, Pagel S, Pott J, Marini F, Reyda S, Kitano M, Macher-Göppinger S, Weiler H, Ruf W) Sci Immunol 2019 Sep 20;4(39) PMID: 31541031 PMCID: PMC6830514 SCOPUS ID: 2-s2.0-85072538893 09/22/2019 79 Citations

Nongenotoxic antibody-drug conjugate conditioning enables safe and effective platelet gene therapy of hemophilia A mice. (Gao C, Schroeder JA, Xue F, Jing W, Cai Y, Scheck A, Subramaniam S, Rao S, Weiler H, Czechowicz A, Shi Q) Blood Adv 2019 Sep 24;3(18):2700-2711 PMID: 31515232 PMCID: PMC6759737 SCOPUS ID: 2-s2.0-85072272107 09/14/2019 35 Citations

The parmodulin NRD-21 is an allosteric inhibitor of PAR1 Gq signaling with improved anti-inflammatory activity and stability. (Gandhi DM, Rosas R Jr, Greve E, Kentala K, D-R Diby N, Snyder VA, Stephans A, Yeung THW, Subramaniam S, DiMilo E, Kurtenbach KE, Arnold LA, Weiler H, Dockendorff C) Bioorg Med Chem 2019 Sep 01;27(17):3788-3796 PMID: 31320211 PMCID: PMC6706283 SCOPUS ID: 2-s2.0-85068855508 07/20/2019 7 Citations

Defective collagen binding and increased bleeding in a murine model of von Willebrand disease affecting collagen IV binding. (Slobodianuk TL, Kochelek C, Foeckler J, Kalloway S, Weiler H, Flood VH) J Thromb Haemost 2019 Jan;17(1):63-71 PMID: 30565388 PMCID: PMC6743498 SCOPUS ID: 2-s2.0-85058806961 12/20/2018 7 Citations

High-resolution mapping of the polyclonal immune response to the human platelet alloantigen HPA-1a (Pl^A1). (Zhi H, Ahlen MT, Thinn AMM, Weiler H, Curtis BR, Skogen B, Zhu J, Newman PJ) Blood Adv 2018 Nov 13;2(21):3001-3011 PMID: 30413435 PMCID: PMC6234362 SCOPUS ID: 2-s2.0-85067320916 11/11/2018 19 Citations

Advances in Clinical and Basic Science of Coagulation: Illustrated abstracts of the 9th Chapel Hill Symposium on Hemostasis. (Bergmeier W, Antoniak S, Conway EM, Denis CV, George LA, Isermann B, Key NS, Krishnaswamy S, Lam WA, Lillicrap D, Liu J, Looney MR, López JA, Maas C, Peyvandi F, Ruf W, Sood AK, Versteeg HH, Wolberg AS, Wong PC, Wood JP, Weiler H) Res Pract Thromb Haemost 2018 Jul;2(3):407-428 PMID: 30046746 PMCID: PMC6046595 SCOPUS ID: 2-s2.0-85069587877 07/27/2018 5 Citations

Factor V Leiden is associated with increased sperm count. (van Mens TE, Joensen UN, Bochdanovits Z, Takizawa A, Peter J, Jørgensen N, Szecsi PB, Meijers JCM, Weiler H, Rajpert-De Meyts E, Repping S, Middeldorp S) Hum Reprod 2017 Nov 01;32(11):2332-2339 PMID: 28927238 SCOPUS ID: 2-s2.0-85047084639 09/21/2017 2 Citations

Variable phenotypic penetrance of thrombosis in adult mice after tissue-selective and temporally controlled Thbd gene inactivation. (van Mens TE, Liang HH, Basu S, Hernandez I, Zogg M, May J, Zhan M, Yang Q, Foeckler J, Kalloway S, Sood R, Karlson CS, Weiler H) Blood Adv 2017 Jun 27;1(15):1148-1158 PMID: 28920104 PMCID: PMC5600150 SCOPUS ID: 2-s2.0-85050503897 09/19/2017 13 Citations

Thrombin promotes diet-induced obesity through fibrin-driven inflammation. (Kopec AK, Abrahams SR, Thornton S, Palumbo JS, Mullins ES, Divanovic S, Weiler H, Owens AP 3rd, Mackman N, Goss A, van Ryn J, Luyendyk JP, Flick MJ) J Clin Invest 2017 Aug 01;127(8):3152-3166 PMID: 28737512 PMCID: PMC5531415 SCOPUS ID: 2-s2.0-85026626202 07/25/2017 90 Citations

TGF-β1 along with other platelet contents augments Treg cells to suppress anti-FVIII immune responses in hemophilia A mice. (Haribhai D, Luo X, Chen J, Jia S, Shi L, Schroeder JA, Weiler H, Aster RH, Hessner MJ, Hu J, Williams CB, Shi Q) Blood Adv 2016 Dec 13;1(2):139-151 PMID: 28164173 PMCID: PMC5288643 02/07/2017

High endogenous activated protein C levels attenuates bleomycin-induced pulmonary fibrosis. (Lin C, von der Thüsen J, Isermann B, Weiler H, van der Poll T, Borensztajn K, Spek CA) J Cell Mol Med 2016 Nov;20(11):2029-2035 PMID: 27295971 PMCID: PMC5082406 SCOPUS ID: 2-s2.0-84977483713 10/27/2016 11 Citations

Nogo-B receptor deficiency increases liver X receptor alpha nuclear translocation and hepatic lipogenesis through an adenosine monophosphate-activated protein kinase alpha-dependent pathway. (Hu W, Zhang W, Chen Y, Rana U, Teng RJ, Duan Y, Liu Z, Zhao B, Foeckler J, Weiler H, Kallinger RE, Thomas MJ, Zhang K, Han J, Miao QR) Hepatology 2016 Nov;64(5):1559-1576 PMID: 27480224 PMCID: PMC5074877 SCOPUS ID: 2-s2.0-84983371299 10/22/2016 28 Citations

Targeting factor VIII expression to platelets for hemophilia A gene therapy does not induce an apparent thrombotic risk in mice. (Baumgartner CK, Mattson JG, Weiler H, Shi Q, Montgomery RR) J Thromb Haemost 2017 Jan;15(1):98-109 PMID: 27496751 PMCID: PMC5280575 SCOPUS ID: 2-s2.0-84997796223 08/09/2016 16 Citations

Nogo-B receptor deficiency causes cerebral vasculature defects during embryonic development in mice. (Rana U, Liu Z, Kumar SN, Zhao B, Hu W, Bordas M, Cossette S, Szabo S, Foeckler J, Weiler H, Chrzanowska-Wodnicka M, Holtz ML, Misra RP, Salato V, North PE, Ramchandran R, Miao QR) Dev Biol 2016 Feb 15;410(2):190-201 PMID: 26746789 PMCID: PMC4767500 SCOPUS ID: 2-s2.0-84957847497 01/10/2016 19 Citations

Myozap Deficiency Promotes Adverse Cardiac Remodeling via Differential Regulation of Mitogen-activated Protein Kinase/Serum-response Factor and β-Catenin/GSK-3β Protein Signaling. (Rangrez AY, Eden M, Poyanmehr R, Kuhn C, Stiebeling K, Dierck F, Bernt A, Lüllmann-Rauch R, Weiler H, Kirchof P, Frank D, Frey N) J Biol Chem 2016 Feb 19;291(8):4128-43 PMID: 26719331 PMCID: PMC4759188 SCOPUS ID: 2-s2.0-84964575923 01/01/2016 22 Citations

Comparison of platelet-derived and plasma factor VIII efficacy using a novel native whole blood thrombin generation assay. (Baumgartner CK, Zhang G, Kuether EL, Weiler H, Shi Q, Montgomery RR) J Thromb Haemost 2015 Dec;13(12):2210-9 PMID: 26453193 PMCID: PMC4715732 SCOPUS ID: 2-s2.0-84958773657 10/11/2015 12 Citations

Coagulation factor V mediates inhibition of tissue factor signaling by activated protein C in mice. (Liang HP, Kerschen EJ, Basu S, Hernandez I, Zogg M, Jia S, Hessner MJ, Toso R, Rezaie AR, Fernández JA, Camire RM, Ruf W, Griffin JH, Weiler H) Blood 2015 Nov 19;126(21):2415-23 PMID: 26341257 PMCID: PMC4653768 SCOPUS ID: 2-s2.0-84948989408 09/06/2015 30 Citations

A balance between TFPI and thrombin-mediated platelet activation is required for murine embryonic development. (Ellery PE, Maroney SA, Cooley BC, Luyendyk JP, Zogg M, Weiler H, Mast AE) Blood 2015 Jun 25;125(26):4078-84 PMID: 25954015 PMCID: PMC4481595 SCOPUS ID: 2-s2.0-84933557679 05/09/2015 18 Citations

Thrombomodulin contributes to gamma tocotrienol-mediated lethality protection and hematopoietic cell recovery in irradiated mice. (Pathak R, Shao L, Ghosh SP, Zhou D, Boerma M, Weiler H, Hauer-Jensen M) PLoS One 2015;10(4):e0122511 PMID: 25860286 PMCID: PMC4393275 SCOPUS ID: 2-s2.0-84928815799 04/11/2015 20 Citations

Quantitative changes in Gimap3 and Gimap5 expression modify mitochondrial DNA segregation in mice. (Jokinen R, Lahtinen T, Marttinen P, Myöhänen M, Ruotsalainen P, Yeung N, Shvetsova A, Kastaniotis AJ, Hiltunen JK, Öhman T, Nyman TA, Weiler H, Battersby BJ) Genetics 2015 May;200(1):221-35 PMID: 25808953 PMCID: PMC4423365 SCOPUS ID: 2-s2.0-84928987108 03/27/2015 8 Citations

EPCR-dependent PAR2 activation by the blood coagulation initiation complex regulates LPS-triggered interferon responses in mice. (Liang HP, Kerschen EJ, Hernandez I, Basu S, Zogg M, Botros F, Jia S, Hessner MJ, Griffin JH, Ruf W, Weiler H) Blood 2015 Apr 30;125(18):2845-54 PMID: 25733582 PMCID: PMC4424632 SCOPUS ID: 2-s2.0-84946801346 03/04/2015 65 Citations

Survival advantage of heterozygous factor V Leiden carriers in murine sepsis. (Kerschen E, Hernandez I, Zogg M, Maas M, Weiler H) J Thromb Haemost 2015 Jun;13(6):1073-80 PMID: 25690763 PMCID: PMC4542152 SCOPUS ID: 2-s2.0-84930182329 02/19/2015 9 Citations

Intraperitoneal administration of activated protein C prevents postsurgical adhesion band formation. (Dinarvand P, Hassanian SM, Weiler H, Rezaie AR) Blood 2015 Feb 19;125(8):1339-48 PMID: 25575539 PMCID: PMC4335085 SCOPUS ID: 2-s2.0-84923378695 01/13/2015 25 Citations

Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism. (Cossette SM, Gastonguay AJ, Bao X, Lerch-Gaggl A, Zhong L, Harmann LM, Koceja C, Miao RQ, Vakeel P, Chun C, Li K, Foeckler J, Bordas M, Weiler H, Strande J, Palecek SP, Ramchandran R) Biol Open 2014 Dec 12;4(1):48-61 PMID: 25505152 PMCID: PMC4295165 SCOPUS ID: 2-s2.0-84979987693 12/17/2014 19 Citations

Overexpression of activated protein C hampers bacterial dissemination during pneumococcal pneumonia. (de Boer JD, Kager LM, Roelofs JJ, Meijers JC, de Boer OJ, Weiler H, Isermann B, van 't Veer C, van der Poll T) BMC Infect Dis 2014 Nov 04;14:559 PMID: 25366058 PMCID: PMC4228088 SCOPUS ID: 2-s2.0-84920825153 11/05/2014 9 Citations

A thrombomodulin mutation that impairs active protein C generation is detrimental in severe pneumonia-derived gram-negative sepsis (melioidosis). (Kager LM, Wiersinga WJ, Roelofs JJ, de Boer OJ, Weiler H, van 't Veer C, van der Poll T) PLoS Negl Trop Dis 2014 Apr;8(4):e2819 PMID: 24762740 PMCID: PMC3998929 SCOPUS ID: 2-s2.0-84901269512 04/26/2014 9 Citations

Inflammation-associated activation of coagulation and immune regulation by the protein C pathway. (Weiler H) Thromb Res 2014 May;133 Suppl 1(0 1):S32-4 PMID: 24759138 PMCID: PMC4060429 SCOPUS ID: 2-s2.0-84898951284 04/25/2014 4 Citations

A conditional knockout mouse model reveals endothelial cells as the principal and possibly exclusive source of plasma factor VIII. (Fahs SA, Hille MT, Shi Q, Weiler H, Montgomery RR) Blood 2014 Jun 12;123(24):3706-13 PMID: 24705491 PMCID: PMC4055921 SCOPUS ID: 2-s2.0-84902594994 04/08/2014 133 Citations

Contributions of thrombin targets to tissue factor-dependent metastasis in hyperthrombotic mice. (Yokota N, Zarpellon A, Chakrabarty S, Bogdanov VY, Gruber A, Castellino FJ, Mackman N, Ellies LG, Weiler H, Ruggeri ZM, Ruf W) J Thromb Haemost 2014 Jan;12(1):71-81 PMID: 24175924 PMCID: PMC3947224 SCOPUS ID: 2-s2.0-84891898669 11/02/2013 29 Citations

Genetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dependent manner. (Borissoff JI, Otten JJ, Heeneman S, Leenders P, van Oerle R, Soehnlein O, Loubele ST, Hamulyák K, Hackeng TM, Daemen MJ, Degen JL, Weiler H, Esmon CT, van Ryn J, Biessen EA, Spronk HM, ten Cate H) PLoS One 2013;8(2):e55784 PMID: 23409043 PMCID: PMC3567111 SCOPUS ID: 2-s2.0-84873592215 02/15/2013 104 Citations

Thrombomodulin regulates keratinocyte differentiation and promotes wound healing. (Cheng TL, Wu YT, Lai CH, Kao YC, Kuo CH, Liu SL, Hsu YY, Chen PK, Cho CF, Wang KC, Lin WL, Chang BI, Chen CM, Weiler H, Shi GY, Wu HL) J Invest Dermatol 2013 Jun;133(6):1638-45 PMID: 23321922 SCOPUS ID: 2-s2.0-84878553610 01/17/2013 22 Citations

Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity. (Geiger H, Pawar SA, Kerschen EJ, Nattamai KJ, Hernandez I, Liang HP, Fernández JÁ, Cancelas JA, Ryan MA, Kustikova O, Schambach A, Fu Q, Wang J, Fink LM, Petersen KU, Zhou D, Griffin JH, Baum C, Weiler H, Hauer-Jensen M) Nat Med 2012 Jul;18(7):1123-9 PMID: 22729286 PMCID: PMC3491776 SCOPUS ID: 2-s2.0-84863683494 06/26/2012 94 Citations

Thrombomodulin is required for the antithrombotic activity of thrombin mutant W215A/E217A in a mouse model of arterial thrombosis. (Vicente CP, Weiler H, Di Cera E, Tollefsen DM) Thromb Res 2012 Oct;130(4):646-8 PMID: 22178578 PMCID: PMC3461961 SCOPUS ID: 2-s2.0-84866241799 12/20/2011 10 Citations

Multiple receptor-mediated functions of activated protein C. (Weiler H) Hamostaseologie 2011 Aug;31(3):185-95 PMID: 21826371 SCOPUS ID: 2-s2.0-80052502628 08/10/2011 32 Citations

Thrombomodulin is a determinant of metastasis through a mechanism linked to the thrombin binding domain but not the lectin-like domain. (Horowitz NA, Blevins EA, Miller WM, Perry AR, Talmage KE, Mullins ES, Flick MJ, Queiroz KC, Shi K, Spek CA, Conway EM, Monia BP, Weiler H, Degen JL, Palumbo JS) Blood 2011 Sep 08;118(10):2889-95 PMID: 21788337 PMCID: PMC3172805 SCOPUS ID: 2-s2.0-80052668558 07/27/2011 72 Citations

Critical role for Gimap5 in the survival of mouse hematopoietic stem and progenitor cells. (Chen Y, Yu M, Dai X, Zogg M, Wen R, Weiler H, Wang D) J Exp Med 2011 May 09;208(5):923-35 PMID: 21502331 PMCID: PMC3092340 SCOPUS ID: 2-s2.0-79956105663 04/20/2011 33 Citations

Myospryn is a calcineurin-interacting protein that negatively modulates slow-fiber-type transformation and skeletal muscle regeneration. (Kielbasa OM, Reynolds JG, Wu CL, Snyder CM, Cho MY, Weiler H, Kandarian S, Naya FJ) FASEB J 2011 Jul;25(7):2276-86 PMID: 21427212 PMCID: PMC3114531 SCOPUS ID: 2-s2.0-79960173494 03/24/2011 31 Citations

Activated protein C targets CD8+ dendritic cells to reduce the mortality of endotoxemia in mice. (Kerschen E, Hernandez I, Zogg M, Jia S, Hessner MJ, Fernandez JA, Griffin JH, Huettner CS, Castellino FJ, Weiler H) J Clin Invest 2010 Sep;120(9):3167-78 PMID: 20714108 PMCID: PMC2929901 SCOPUS ID: 2-s2.0-77956372381 08/18/2010 83 Citations

Targeting FVIII expression to endothelial cells regenerates a releasable pool of FVIII and restores hemostasis in a mouse model of hemophilia A. (Shi Q, Fahs SA, Kuether EL, Cooley BC, Weiler H, Montgomery RR) Blood 2010 Oct 21;116(16):3049-57 PMID: 20606161 PMCID: PMC2974610 SCOPUS ID: 2-s2.0-77958193310 07/08/2010 41 Citations

Factor V Leiden mutation enhances fibrin formation and dissolution in vivo in a human endotoxemia model. (Elmas E, Suvajac N, Jilma B, Weiler H, Borggrefe M, Dempfle CE) Blood 2010 Aug 05;116(5):801-5 PMID: 20410502 SCOPUS ID: 2-s2.0-77956285538 04/23/2010 9 Citations

Age-dependent vulnerability to endotoxemia is associated with reduction of anticoagulant factors activated protein C and thrombomodulin. (Starr ME, Ueda J, Takahashi H, Weiler H, Esmon CT, Evers BM, Saito H) Blood 2010 Jun 10;115(23):4886-93 PMID: 20348393 PMCID: PMC2890181 SCOPUS ID: 2-s2.0-77954738683 03/30/2010 58 Citations

Regulation of inflammation by the protein C system. (Weiler H) Crit Care Med 2010 Feb;38(2 Suppl):S18-25 PMID: 20083909 SCOPUS ID: 2-s2.0-74949109112 01/30/2010 36 Citations

Elevated fibrinogen γ′ ratios and clinical outcomes (Nowak-Göttl U, Weiler H, Stoll M) Blood 12 November 2009;114(20):4604-4605 SCOPUS ID: 2-s2.0-77950455511 11/12/2009

Hypercoagulability inhibits monocyte transendothelial migration through protease-activated receptor-1-, phospholipase-Cbeta-, phosphoinositide 3-kinase-, and nitric oxide-dependent signaling in monocytes and promotes plaque stability. (Seehaus S, Shahzad K, Kashif M, Vinnikov IA, Schiller M, Wang H, Madhusudhan T, Eckstein V, Bierhaus A, Bea F, Blessing E, Weiler H, Frommhold D, Nawroth PP, Isermann B) Circulation 2009 Sep 01;120(9):774-84 PMID: 19687358 SCOPUS ID: 2-s2.0-70349330117 08/19/2009 63 Citations

Preface (Flaumenhaft R, Aird WC, Bouchard BA, Byzova TV, Croce K, Gibbins JM, Gross PL, Heit JA, Italiano JE, Liebman H, López JA, Mackman N, Peyvandi F, Wagner DD, Warkentin T, Weiler H, Zwicker J) Journal of Thrombosis and Haemostasis 2009;7(SUPPL. 1) SCOPUS ID: 2-s2.0-67849095441 08/04/2009

Modulation of sepsis outcome with variants of activated protein C. (Weiler H, Kerschen E) J Thromb Haemost 2009 Jul;7 Suppl 1:127-31 PMID: 19630784 SCOPUS ID: 2-s2.0-67849104659 07/28/2009 4 Citations

Knockout rats via embryo microinjection of zinc-finger nucleases. (Geurts AM, Cost GJ, Freyvert Y, Zeitler B, Miller JC, Choi VM, Jenkins SS, Wood A, Cui X, Meng X, Vincent A, Lam S, Michalkiewicz M, Schilling R, Foeckler J, Kalloway S, Weiler H, Ménoret S, Anegon I, Davis GD, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Jacob HJ, Buelow R) Science 2009 Jul 24;325(5939):433 PMID: 19628861 PMCID: PMC2831805 SCOPUS ID: 2-s2.0-67749106611 07/25/2009 780 Citations

Fibrinogen alpha and gamma genes and factor VLeiden in children with thromboembolism: results from 2 family-based association studies. (Nowak-Göttl U, Weiler H, Hernandez I, Thedieck S, Seehafer T, Schulte T, Stoll M) Blood 2009 Aug 27;114(9):1947-53 PMID: 19515723 SCOPUS ID: 2-s2.0-70349249995 06/12/2009 30 Citations

Hyperantithrombotic, noncytoprotective Glu149Ala-activated protein C mutant. (Mosnier LO, Zampolli A, Kerschen EJ, Schuepbach RA, Banerjee Y, Fernández JA, Yang XV, Riewald M, Weiler H, Ruggeri ZM, Griffin JH) Blood 2009 Jun 04;113(23):5970-8 PMID: 19244160 PMCID: PMC2700330 SCOPUS ID: 2-s2.0-67651083688 02/27/2009 64 Citations

Endogenous EPCR/aPC-PAR1 signaling prevents inflammation-induced vascular leakage and lethality. (Niessen F, Furlan-Freguia C, Fernández JA, Mosnier LO, Castellino FJ, Weiler H, Rosen H, Griffin JH, Ruf W) Blood 2009 Mar 19;113(12):2859-66 PMID: 19141861 PMCID: PMC2661868 SCOPUS ID: 2-s2.0-63849278353 01/15/2009 72 Citations

Caveolin-1-dependent apoptosis induced by fibrin degradation products. (Guo YH, Hernandez I, Isermann B, Kang TB, Medved L, Sood R, Kerschen EJ, Holyst T, Mosesson MW, Weiler H) Blood 2009 Apr 30;113(18):4431-9 PMID: 19074731 PMCID: PMC2676096 SCOPUS ID: 2-s2.0-66149083175 12/17/2008 34 Citations

Thrombosis risk modification in transgenic mice containing the human fibrinogen thrombin-binding gamma' chain sequence. (Mosesson MW, Cooley BC, Hernandez I, Diorio JP, Weiler H) J Thromb Haemost 2009 Jan;7(1):102-10 PMID: 18983496 SCOPUS ID: 2-s2.0-57749203814 11/06/2008 25 Citations

Calsarcin-2 deficiency increases exercise capacity in mice through calcineurin/NFAT activation. (Frey N, Frank D, Lippl S, Kuhn C, Kögler H, Barrientos T, Rohr C, Will R, Müller OJ, Weiler H, Bassel-Duby R, Katus HA, Olson EN) J Clin Invest 2008 Nov;118(11):3598-608 PMID: 18846255 PMCID: PMC2564612 SCOPUS ID: 2-s2.0-55849135238 10/11/2008 121 Citations

Tracing the molecular pathogenesis of antiphospholipid syndrome. (Weiler H) J Clin Invest 2008 Oct;118(10):3276-8 PMID: 18802489 PMCID: PMC2542859 SCOPUS ID: 2-s2.0-55849139466 09/20/2008 12 Citations

Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5. (Schulteis RD, Chu H, Dai X, Chen Y, Edwards B, Haribhai D, Williams CB, Malarkannan S, Hessner MJ, Glisic-Milosavljevic S, Jana S, Kerschen EJ, Ghosh S, Wang D, Kwitek AE, Lernmark A, Gorski J, Weiler H) Blood 2008 Dec 15;112(13):4905-14 PMID: 18796632 PMCID: PMC2597598 SCOPUS ID: 2-s2.0-58149376483 09/18/2008 54 Citations

Activated protein C in sepsis: the promise of nonanticoagulant activated protein C. (Weiler H, Ruf W) Curr Opin Hematol 2008 Sep;15(5):487-93 PMID: 18695372 PMCID: PMC2742321 SCOPUS ID: 2-s2.0-55249086326 08/13/2008 29 Citations

Syngeneic transplantation of hematopoietic stem cells that are genetically modified to express factor VIII in platelets restores hemostasis to hemophilia A mice with preexisting FVIII immunity. (Shi Q, Fahs SA, Wilcox DA, Kuether EL, Morateck PA, Mareno N, Weiler H, Montgomery RR) Blood 2008 Oct 01;112(7):2713-21 PMID: 18495954 PMCID: PMC2556608 SCOPUS ID: 2-s2.0-53449090226 05/23/2008 84 Citations

Maternal Par4 and platelets contribute to defective placenta formation in mouse embryos lacking thrombomodulin. (Sood R, Sholl L, Isermann B, Zogg M, Coughlin SR, Weiler H) Blood 2008 Aug 01;112(3):585-91 PMID: 18490515 PMCID: PMC2481555 SCOPUS ID: 2-s2.0-50949133923 05/21/2008 34 Citations

Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis. (Isermann B, Vinnikov IA, Madhusudhan T, Herzog S, Kashif M, Blautzik J, Corat MA, Zeier M, Blessing E, Oh J, Gerlitz B, Berg DT, Grinnell BW, Chavakis T, Esmon CT, Weiler H, Bierhaus A, Nawroth PP) Nat Med 2007 Nov;13(11):1349-58 PMID: 17982464 SCOPUS ID: 2-s2.0-35948934636 11/06/2007 346 Citations

Combined tissue factor pathway inhibitor and thrombomodulin deficiency produces an augmented hypercoagulable state with tissue-specific fibrin deposition. (Maroney SA, Cooley BC, Sood R, Weiler H, Mast AE) J Thromb Haemost 2008 Jan;6(1):111-7 PMID: 17973652 PMCID: PMC3646640 SCOPUS ID: 2-s2.0-37548998987 11/02/2007 28 Citations

PAR4 antagonists in inflammation (Weiler H, Ruf W) Blood 1 November 2007;110(9):3091-3092 SCOPUS ID: 2-s2.0-36148985361 11/01/2007 1 Citation

Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C. (Kerschen EJ, Fernandez JA, Cooley BC, Yang XV, Sood R, Mosnier LO, Castellino FJ, Mackman N, Griffin JH, Weiler H) J Exp Med 2007 Oct 01;204(10):2439-48 PMID: 17893198 PMCID: PMC2118455 SCOPUS ID: 2-s2.0-34948866150 09/26/2007 263 Citations

Endothelial protein C receptor: location...with a pool! (Weiler H) J Thromb Haemost 2007 Jul;5(7):1391-3 PMID: 17456191 SCOPUS ID: 2-s2.0-34250706235 04/26/2007 1 Citation

Fetal gene defects precipitate platelet-mediated pregnancy failure in factor V Leiden mothers. (Sood R, Zogg M, Westrick RJ, Guo YH, Kerschen EJ, Girardi G, Salmon JE, Coughlin SR, Weiler H) J Exp Med 2007 May 14;204(5):1049-56 PMID: 17438064 PMCID: PMC2118565 SCOPUS ID: 2-s2.0-34249051898 04/18/2007 36 Citations

Endothelial mimicry of placental trophoblast cells (Weiler H, Sood R) Endothelial Biomedicine 1 January 2007:1479-1487 SCOPUS ID: 2-s2.0-67649461784 01/01/2007 1 Citation

Factor VIII ectopically targeted to platelets is therapeutic in hemophilia A with high-titer inhibitory antibodies. (Shi Q, Wilcox DA, Fahs SA, Weiler H, Wells CW, Cooley BC, Desai D, Morateck PA, Gorski J, Montgomery RR) J Clin Invest 2006 Jul;116(7):1974-82 PMID: 16823491 PMCID: PMC1483176 SCOPUS ID: 2-s2.0-33745864802 07/11/2006 151 Citations

Myospryn is a direct transcriptional target for MEF2A that encodes a striated muscle, alpha-actinin-interacting, costamere-localized protein. (Durham JT, Brand OM, Arnold M, Reynolds JG, Muthukumar L, Weiler H, Richardson JA, Naya FJ) J Biol Chem 2006 Mar 10;281(10):6841-9 PMID: 16407236 SCOPUS ID: 2-s2.0-33646559605 01/13/2006 43 Citations

Fetomaternal cross talk in the placental vascular bed: control of coagulation by trophoblast cells. (Sood R, Kalloway S, Mast AE, Hillard CJ, Weiler H) Blood 2006 Apr 15;107(8):3173-80 PMID: 16380449 PMCID: PMC1895751 SCOPUS ID: 2-s2.0-33645746632 12/29/2005 88 Citations

Platelet PECAM-1 inhibits thrombus formation in vivo. (Falati S, Patil S, Gross PL, Stapleton M, Merrill-Skoloff G, Barrett NE, Pixton KL, Weiler H, Cooley B, Newman DK, Newman PJ, Furie BC, Furie B, Gibbins JM) Blood 2006 Jan 15;107(2):535-41 PMID: 16166583 PMCID: PMC1895610 SCOPUS ID: 2-s2.0-30444452396 09/17/2005 177 Citations

Thrombophilia and pregnancy failure: feto-maternal interactions in the vascular bed of the placenta. (Sood R, Kalloway S, Mast AE, Weiler H) Thromb Res 2005 Feb;115 Suppl 1:92-4 PMID: 15790167 SCOPUS ID: 2-s2.0-12544257871 03/26/2005 2 Citations

It's the trophoblast! (Weiler H) Blood October 2005;106(8):2603 SCOPUS ID: 2-s2.0-27144531742 01/01/2005

Vascular biology of the placenta (Weiler H) Endothelial Cells in Health and Disease 1 January 2005:245-264 SCOPUS ID: 2-s2.0-85056521923 01/01/2005 2 Citations

Restricted inactivation of serum response factor to the cardiovascular system. (Miano JM, Ramanan N, Georger MA, de Mesy Bentley KL, Emerson RL, Balza RO Jr, Xiao Q, Weiler H, Ginty DD, Misra RP) Proc Natl Acad Sci U S A 2004 Dec 07;101(49):17132-7 PMID: 15569937 PMCID: PMC535359 SCOPUS ID: 2-s2.0-10344236515 12/01/2004 211 Citations

Mouse models of thrombosis: thrombomodulin. (Weiler H) Thromb Haemost 2004 Sep;92(3):467-77 PMID: 15351842 SCOPUS ID: 2-s2.0-12344277910 09/08/2004 33 Citations

Role of fibrinogen- and platelet-mediated hemostasis in mouse embryogenesis and reproduction. (Palumbo JS, Zogg M, Talmage KE, Degen JL, Weiler H, Isermann BH) J Thromb Haemost 2004 Aug;2(8):1368-79 PMID: 15304043 SCOPUS ID: 2-s2.0-2942624713 08/12/2004 35 Citations

Factor V Leiden polymorphism modifies sepsis outcome: evidence from animal studies. (Weiler H, Kerlin B, Lytle MC) Crit Care Med 2004 May;32(5 Suppl):S233-8 PMID: 15118524 SCOPUS ID: 2-s2.0-2942709619 05/01/2004 33 Citations

Cause-effect relation between hyperfibrinogenemia and vascular disease. (Kerlin B, Cooley BC, Isermann BH, Hernandez I, Sood R, Zogg M, Hendrickson SB, Mosesson MW, Lord S, Weiler H) Blood 2004 Mar 01;103(5):1728-34 PMID: 14615369 SCOPUS ID: 2-s2.0-10744231546 11/15/2003 85 Citations

Thrombomodulin. (Weiler H, Isermann BH) J Thromb Haemost 2003 Jul;1(7):1515-24 PMID: 12871287 SCOPUS ID: 2-s2.0-0141498158 07/23/2003 225 Citations

Survival advantage associated with heterozygous factor V Leiden mutation in patients with severe sepsis and in mouse endotoxemia. (Kerlin BA, Yan SB, Isermann BH, Brandt JT, Sood R, Basson BR, Joyce DE, Weiler H, Dhainaut JF) Blood 2003 Nov 01;102(9):3085-92 PMID: 12869495 SCOPUS ID: 2-s2.0-0142245617 07/19/2003 140 Citations

Embryogenesis and gene targeting of coagulation factors in mice. (Sood R, Weiler H) Best Pract Res Clin Haematol 2003 Jun;16(2):169-81 PMID: 12763485 SCOPUS ID: 2-s2.0-0038656542 05/24/2003 5 Citations

The thrombomodulin-protein C system is essential for the maintenance of pregnancy. (Isermann B, Sood R, Pawlinski R, Zogg M, Kalloway S, Degen JL, Mackman N, Weiler H) Nat Med 2003 Mar;9(3):331-7 PMID: 12579195 SCOPUS ID: 2-s2.0-0037349926 02/13/2003 230 Citations

The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways. (Conway EM, Van de Wouwer M, Pollefeyt S, Jurk K, Van Aken H, De Vriese A, Weitz JI, Weiler H, Hellings PW, Schaeffer P, Herbert JM, Collen D, Theilmeier G) J Exp Med 2002 Sep 02;196(5):565-77 PMID: 12208873 PMCID: PMC2193995 SCOPUS ID: 2-s2.0-0036719075 09/05/2002 315 Citations

Mouse models in coagulation. (Hogan KA, Weiler H, Lord ST) Thromb Haemost 2002 Apr;87(4):563-74 PMID: 12008936 SCOPUS ID: 2-s2.0-0036217996 05/15/2002 45 Citations

Expression of human smooth muscle calponin in transgenic mice revealed with a bacterial artificial chromosome. (Miano JM, Kitchen CM, Chen J, Maltby KM, Kelly LA, Weiler H, Krahe R, Ashworth LK, Garcia E) Am J Physiol Heart Circ Physiol 2002 May;282(5):H1793-803 PMID: 11959645 SCOPUS ID: 2-s2.0-0036088084 04/18/2002 12 Citations

Characterization of a mouse model for thrombomodulin deficiency. (Weiler H, Lindner V, Kerlin B, Isermann BH, Hendrickson SB, Cooley BC, Meh DA, Mosesson MW, Shworak NW, Post MJ, Conway EM, Ulfman LH, von Andrian UH, Weitz JI) Arterioscler Thromb Vasc Biol 2001 Sep;21(9):1531-7 PMID: 11557684 SCOPUS ID: 2-s2.0-0035572892 09/15/2001 130 Citations

Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosis. (Isermann B, Hendrickson SB, Zogg M, Wing M, Cummiskey M, Kisanuki YY, Yanagisawa M, Weiler H) J Clin Invest 2001 Aug;108(4):537-46 PMID: 11518727 PMCID: PMC209404 SCOPUS ID: 2-s2.0-0034892611 08/24/2001 119 Citations

An efficient method to successively introduce transgenes into a given genomic locus in the mouse. (Zhao R, Fahs SA, Weiler H, Duncan SA) BMC Dev Biol 2001;1:10 PMID: 11430765 PMCID: PMC33517 SCOPUS ID: 2-s2.0-3042760395 06/30/2001 3 Citations

Tissue-restricted expression of thrombomodulin in the placenta rescues thrombomodulin-deficient mice from early lethality and reveals a secondary developmental block. (Isermann B, Hendrickson SB, Hutley K, Wing M, Weiler H) Development 2001 Mar;128(6):827-38 PMID: 11222138 SCOPUS ID: 2-s2.0-0035070573 02/27/2001 84 Citations

The basic helix-loop-helix transcription factor capsulin controls spleen organogenesis. (Lu J, Chang P, Richardson JA, Gan L, Weiler H, Olson EN) Proc Natl Acad Sci U S A 2000 Aug 15;97(17):9525-30 PMID: 10944221 PMCID: PMC16898 SCOPUS ID: 2-s2.0-0034662960 08/16/2000 111 Citations

Targeted mutagenesis of thrombomodulin (TM) generates adult mice with thrombotic lesions in specific vascular beds (Rosenberg RD, Weiler H, Christic P, Ravburn H, Beeler D) FASEB Journal 1997;11(9) SCOPUS ID: 2-s2.0-33750226235 12/01/1997

Absence of the blood-clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system. (Healy AM, Rayburn HB, Rosenberg RD, Weiler H) Proc Natl Acad Sci U S A 1995 Jan 31;92(3):850-4 PMID: 7846065 PMCID: PMC42718 SCOPUS ID: 2-s2.0-0028876697 01/31/1995 224 Citations

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Profiles for MCW, MU, MSOE, UWM, BCW, CW, Froedtert, and VA Faculty

Hartmut Weiler PhD

Associate Professor

Publications (117)