Medical College of Wisconsin
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Jake Luo Ph.D.

Jake Luo Ph.D. profile photo picture

Associate Professor; Director, Center for Biomedical Data and Language Processing (BioDLP)

Institution: University of Wisconsin - Milwaukee
Department: Health Informatics & Administration

image of /images/ORCIDiD_icon16x16.png   https://orcid.org/0000-0002-3900-643X


I am willing to collaborate on research projects.
I am willing to mentor a junior faculty member.

View Curriculum Vitae

Research Experience

  • Algorithms
  • Artificial Intelligence
  • Consumer Health Information
  • Data Mining
  • Decision Support Systems, Clinical
  • Evidence-Based Medicine
  • Information Science
  • Information Storage and Retrieval
  • Medical Informatics
  • Natural Language Processing
  • Patient Selection
  • Unified Medical Language System
  • User-Computer Interface
  • Data Visualization
  • Knowledge Representation
  • Optimization
  • Predictive Analysis
  • Data Mining
  • Electronic Health Records
  • Big Data
  • Machine Learning
  • Clinical Research Informatics
  • Reinforcement Learning
  • Data Science
  • Information Extraction
  • Deep Learning

    • Clinical Expertise

  • Algorithms
  • Biomedical Research
  • Clinical Trials as Topic
  • Consumer Health Information
  • Data Mining
  • Information Storage and Retrieval
  • Natural Language Processing
  • Patient Selection
  • Semantics
  • Unified Medical Language System
  • User-Computer Interface

    • Methodologies and Techniques

  • Data mining on clinical and biomedical research datasets
  • Search, retrieve, and analyze consumer health information
  • Apply artificial intelligence methods to optimize decision and process
  • Formalize information (e.g. patient characteristics) from free-text documents
  • developing mobile app (mHealth) to deliver healthcare information for consumers
  • Extract information from electronic health records
  • Process free-text documents, e.g. discharge summaries, patient histories, social media posts
  • Multidisciplinary team science collaboration
  • Data mining on large-scale (million) patient datasets
  • Develop clinical decision support systems
  • Using data mining to find adverse event outliers
  • Data-driven analysis of risks of disorders
  • Visualize data in an intuitive and interesting way
  • Integrate and capture clinical research data into database
  • Discovering hidden patterns in clinical data, such as electronic health records
  • Create novel software application to support healthcare
  • Develop Novel machine learning algorithms
  • Leverage machine learning algorithms to predict outcomes, e.g. adverse events, treatment effectiveness

    • Leadership Positions

  • Director of Center for Health System Solutions
  • Director of Health Informatics Graduate Program at UWM

    • MCW Program / Core Facilities

  • clinical & Translational Science Institute (CTSI)
  • Director of Center for Biomedical Data and Language Processing

    • Educational Expertise

  • Medical Informatics
  • Big Data Mining
  • Medical Informatics
  • Health Informatics Application
  • Healthcare and clinical information system architecture and design
  • Clinical Research Informatics

    • Publications (66)

  • Disparities in polysomnography referral in a high-risk cardiac population. (Koss KR, Kumar D, Friedland DR, Adams JA, Lauer KK, Tong L, Luo J, Woodson BT) Sleep Breath 2024 Jun 18 PMID: 38890269 SCOPUS ID: 2-s2.0-85196291059 06/19/2024    
  • Creation and analysis of a Lao American collaborative medical education facebook page. (Baca AR, Saysanasongkham S, Wallace C, Seballos SS, Konphanthavong S, Khamvongsa S, Luo J, Cohn KA) Educ Health (Abingdon) 2023;36(1):47-48 PMID: 38047347 SCOPUS ID: 2-s2.0-85178649861 12/04/2023       1 Citation
  • Factors associated with delayed referral and hearing rehabilitation for congenital sensorineural hearing loss. (Drake M, Friedland DR, Hamad B, Marfowaa G, Adams JA, Luo J, Flanary V) Int J Pediatr Otorhinolaryngol 2023 Dec;175:111770 PMID: 37890209 SCOPUS ID: 2-s2.0-85174694338 10/28/2023       1 Citation
  • A Survey of Conversational Agents and Their Applications for Self-Management of Chronic Conditions. (Park MS, Upama PB, Anik AA, Ahamed SI, Luo J, Tian S, Rabbani M, Oh H) Proc COMPSAC 2023 Jun;2023:1064-1075 PMID: 37750107 PMCID: PMC10519706 SCOPUS ID: 2-s2.0-85168908873 09/26/2023    
  • Evaluation of Social Determinants of Health on Dysphagia Care Pathways at a Tertiary Care Facility. (Zagloul MM, Bock JM, Blumin JH, Friedland DR, Adams JA, Tong L, Osinksi KI, Khani M, Luo J) Laryngoscope 2024 Mar;134(3):1139-1146 PMID: 37681733 SCOPUS ID: 2-s2.0-85170398108 09/08/2023    
  • CenhANCER: a comprehensive cancer enhancer database for primary tissues and cell lines. (Luo ZH, Shi MW, Zhang Y, Wang DY, Tong YB, Pan XL, Cheng S) Database (Oxford) 2023 May 18;2023 PMID: 37207350 PMCID: PMC10198702 SCOPUS ID: 2-s2.0-85159723701 05/19/2023       1 Citation
  • Impacts of Socioeconomic Status on Dentoalveolar Trauma. (Feller CN, Adams JA, Friedland DR, Khani M, Luo J, Poetker DM) WMJ 2023 Mar;122(1):32-37 PMID: 36940119 SCOPUS ID: 2-s2.0-85150752032 03/21/2023    
  • Towards Developing a Voice-activated Self-monitoring Application (VoiS) for Adults with Diabetes and Hypertension. (Rabbani M, Tian S, Anik AA, Luo J, Park MS, Whittle J, Ahamed SI, Oh H) Proc COMPSAC 2022;2022:512-519 PMID: 36594906 PMCID: PMC9805835 01/04/2023    
  • Association between body-mass index, patient characteristics, and obesity-related comorbidities among COVID-19 patients: A prospective cohort study. (Tong L, Khani M, Lu Q, Taylor B, Osinski K, Luo J) Obes Res Clin Pract 2023;17(1):47-57 PMID: 36577559 PMCID: PMC9763214 SCOPUS ID: 2-s2.0-85147664081 12/29/2022       8 Citations
  • Demographic differences in the treatment of unilateral vocal fold paralysis. (Patel MA, Bock JM, Blumin JH, Friedland DR, Adams JA, Tong L, Osinski KI, Luo J) Laryngoscope Investig Otolaryngol 2022 Dec;7(6):1915-1921 PMID: 36544963 PMCID: PMC9764816 SCOPUS ID: 2-s2.0-85139002323 12/23/2022       2 Citations
  • Circ_0001777 Affects Triple-negative Breast Cancer Progression Through the miR-95-3p/AKAP12 Axis. (Chen Z, Gong X, Cheng C, Fu Y, Wu W, Luo Z) Clin Breast Cancer 2023 Feb;23(2):143-154 PMID: 36513585 SCOPUS ID: 2-s2.0-85143861887 12/14/2022       3 Citations
  • The Demographics of Menière's Disease: Selection Bias or Differential Susceptibility? (Thompson-Harvey A, Friedland DR, Adams JA, Tong L, Osinski K, Luo J) Otol Neurotol 2023 Feb 01;44(2):e95-e102 PMID: 36477093 PMCID: PMC9839510 SCOPUS ID: 2-s2.0-85145973407 12/09/2022       2 Citations
  • Telemedicine and health disparities: Association between patient characteristics and telemedicine, in-person, telephone and message-based care during the COVID-19 pandemic. (Tong L, George B, Crotty BH, Somai M, Taylor BW, Osinski K, Luo J) IPEM Transl 2022;3:100010 PMID: 36340828 PMCID: PMC9617798 11/08/2022    
  • Standardization of Outcome Measures for Intratympanic Steroid Treatment for Idiopathic Sudden Sensorineural Hearing Loss. (Osafo NK, Friedland DR, Harris MS, Adams J, Davis C, Osinski K, Tong L, Luo J) Otol Neurotol 2022 Dec 01;43(10):1137-1143 PMID: 36190905 SCOPUS ID: 2-s2.0-85141892655 10/04/2022       3 Citations
  • Proposed Questions to Assess the Extent of Knowledge in Understanding the Radiology Report Language. (Alarifi M, Jabour AM, Wu M, Aldosary A, Almanaa M, Luo J) Int J Environ Res Public Health 2022 Sep 19;19(18) PMID: 36142078 PMCID: PMC9517641 SCOPUS ID: 2-s2.0-85138377111 09/24/2022    
  • Impact of Demographics and Clinical Features on Initial Treatment Pathway for Vestibular Schwannoma. (Harvey E, Stark K, Friedland DR, Adams JA, Harris MS, Tong L, Osinksi K, Luo J) Otol Neurotol 2022 Oct 01;43(9):1078-1084 PMID: 35960883 PMCID: PMC9878333 SCOPUS ID: 2-s2.0-85138449091 08/13/2022       2 Citations
  • Analysis of socioeconomic factors in laryngology clinic utilization for treatment of dysphonia. (White SW, Bock JM, Blumin JH, Friedland DR, Adams JA, Tong L, Osinski K, Luo J) Laryngoscope Investig Otolaryngol 2022 Feb;7(1):202-209 PMID: 35155799 PMCID: PMC8823153 SCOPUS ID: 2-s2.0-85122043790 02/15/2022       4 Citations
  • Predicting Risk of Stroke From Lab Tests Using Machine Learning Algorithms: Development and Evaluation of Prediction Models. (Alanazi EM, Abdou A, Luo J) JMIR Form Res 2021 Dec 02;5(12):e23440 PMID: 34860663 PMCID: PMC8686476 SCOPUS ID: 2-s2.0-85121460631 12/04/2021       13 Citations
  • The impact of social determinants of health and clinical comorbidities on post-tympanotomy tube otorrhea. (Thomas A, Flanary V, Friedland DR, Adams JA, Tong L, Osinski K, Luo J) Int J Pediatr Otorhinolaryngol 2022 Jan;152:110986 PMID: 34839989 SCOPUS ID: 2-s2.0-85119900309 11/30/2021       5 Citations
  • Telemedicine Adoption during the COVID-19 Pandemic: Gaps and Inequalities. (Luo J, Tong L, Crotty BH, Somai M, Taylor B, Osinski K, George B) Appl Clin Inform 2021 Aug;12(4):836-844 PMID: 34496419 PMCID: PMC8426040 SCOPUS ID: 2-s2.0-85114767728 09/09/2021       60 Citations
  • Socioeconomic Determinants of Tertiary Rhinology Care Utilization. (Poetker DM, Friedland DR, Adams JA, Tong L, Osinski K, Luo J) OTO Open 2021;5(2):2473974X211009830 PMID: 33948528 PMCID: PMC8053774 SCOPUS ID: 2-s2.0-85106709611 05/06/2021       13 Citations
  • Designing a Consumer-Friendly Radiology Report using a Patient-Centered Approach. (Alarifi M, Patrick T, Jabour A, Wu M, Luo J) J Digit Imaging 2021 Jun;34(3):705-716 PMID: 33903982 PMCID: PMC8329124 SCOPUS ID: 2-s2.0-85105358627 04/28/2021       4 Citations
  • Understanding patient needs and gaps in radiology reports through online discussion forum analysis. (Alarifi M, Patrick T, Jabour A, Wu M, Luo J) Insights Imaging 2021 Apr 19;12(1):50 PMID: 33871753 PMCID: PMC8055745 SCOPUS ID: 2-s2.0-85104649555 04/20/2021       16 Citations
  • Meeting the COVID Challenge to a Research-intensive Pre-college Science Education Program. (Berg C, Carvan M, Hesselbach R, Luo Z, Petering D, Pickart M, Tomasiewicz H, Weber D, Shukla R, Goldberg B) J STEM Outreach 2021;4(2) PMID: 36304133 PMCID: PMC9605687 01/01/2021    
  • Social factors shaping the adoption of lead-filtering point-of-use systems: an observational study of an MTurk sample. (Chesley N, Meier H, Luo J, Apchemengich I, Davies WH) J Water Health 2020 Aug;18(4):505-521 PMID: 32833677 SCOPUS ID: 2-s2.0-85089925361 08/25/2020       1 Citation
  • Full Radiology Report through Patient Web Portal: A Literature Review. (Alarifi M, Patrick T, Jabour A, Wu M, Luo J) Int J Environ Res Public Health 2020 May 22;17(10) PMID: 32456099 PMCID: PMC7277373 SCOPUS ID: 2-s2.0-85085256852 05/28/2020       12 Citations
  • Adoption of Hospital Information System Among Nurses: a Technology Acceptance Model Approach. (Barzekar H, Ebrahimzadeh F, Luo J, Karami M, Robati Z, Goodarzi P) Acta Inform Med 2019 Dec;27(5):305-310 PMID: 32210497 PMCID: PMC7085343 SCOPUS ID: 2-s2.0-85085944955 03/27/2020       17 Citations
  • The PsyTAR dataset: From patients generated narratives to a corpus of adverse drug events and effectiveness of psychiatric medications. (Zolnoori M, Fung KW, Patrick TB, Fontelo P, Kharrazi H, Faiola A, Shah ND, Shirley Wu YS, Eldredge CE, Luo J, Conway M, Zhu J, Park SK, Xu K, Moayyed H) Data Brief 2019 Jun;24:103838 PMID: 31065579 PMCID: PMC6495095 SCOPUS ID: 2-s2.0-85064767380 05/09/2019       29 Citations
  • A systematic approach for developing a corpus of patient reported adverse drug events: A case study for SSRI and SNRI medications. (Zolnoori M, Fung KW, Patrick TB, Fontelo P, Kharrazi H, Faiola A, Wu YSS, Eldredge CE, Luo J, Conway M, Zhu J, Park SK, Xu K, Moayyed H, Goudarzvand S) J Biomed Inform 2019 Feb;90:103091 PMID: 30611893 SCOPUS ID: 2-s2.0-85060100705 01/07/2019       28 Citations
  • A Principal Components Analysis Approach to Quantifying Foot Clearance and Foot Clearance Variability. (Benson LC, Cobb SC, Hyngstrom AS, Keenan KG, Luo J, O'Connor KM) J Appl Biomech 2019 Apr 01;35(2):116-122 PMID: 30421634 SCOPUS ID: 2-s2.0-85062843463 11/14/2018       9 Citations
  • Identifying trippers and non-trippers based on knee kinematics during obstacle-free walking. (Benson LC, Cobb SC, Hyngstrom AS, Keenan KG, Luo J, O'Connor KM) Hum Mov Sci 2018 Dec;62:58-66 PMID: 30245267 SCOPUS ID: 2-s2.0-85053781059 09/25/2018       9 Citations
  • Unique Clinical Language Patterns Among Expert Vestibular Providers Can Predict Vestibular Diagnoses. (Luo J, Erbe C, Friedland DR) Otol Neurotol 2018 Oct;39(9):1163-1171 PMID: 30080764 SCOPUS ID: 2-s2.0-85056607740 08/07/2018       5 Citations
  • Using data-driven sublanguage pattern mining to induce knowledge models: application in medical image reports knowledge representation. (Zhao Y, Fesharaki NJ, Liu H, Luo J) BMC Med Inform Decis Mak 2018 Jul 06;18(1):61 PMID: 29980203 PMCID: PMC6035419 SCOPUS ID: 2-s2.0-85049685166 07/08/2018       7 Citations
  • Semantic-Enhanced Query Expansion System for Retrieving Medical Image Notes. (Zhao Y, Fesharaki NJ, Li X, Patrick TB, Luo J) J Med Syst 2018 Apr 25;42(6):105 PMID: 29696548 SCOPUS ID: 2-s2.0-85046355051 04/27/2018       5 Citations
  • Systematic data ingratiation of clinical trial recruitment locations for geographic-based query and visualization. (Luo J, Chen W, Wu M, Weng C) Int J Med Inform 2017 Dec;108:85-91 PMID: 29132636 PMCID: PMC5866921 SCOPUS ID: 2-s2.0-85031730676 11/15/2017       2 Citations
  • Using a Single Ankle-Worn Accelerometer to Predict Lower Extremity Joint Range of Motion (Benson LC, Cobb SC, Hyngstrom A, Keenan KG, Luo J, O'Connor KM) Congress of the International Society of Biomechanics (ISB'2017) 06/07/2017    
  • Physicians Satisfaction With Clinical Decision Support System: An Examination Of Alerts And Alert Fatigue (Alarifi M, Luo J, Almanaa M, Altuwayjiri E) 2nd International Saudi Health Informatics Conference (ISHIC 2017) 05/12/2017    
  • Geographical Distribution and Trends of Clinical Trial Recruitment Sites in Developing and Developed Countries (Luo J, Wu M, Chen W) Journal of Health Informatics in Developing Countries (JHIDC) 04/26/2017    
  • Discovering Outliers of Potential Drug Toxicities Using a Large-scale Data-driven Approach. (Luo J, Cisler RA) Cancer Inform 2016;15:211-217 PMID: 27812279 PMCID: PMC5083124 SCOPUS ID: 2-s2.0-84994032190 11/05/2016       3 Citations
  • Population Analysis of Adverse Events in Different Age Groups Using Big Clinical Trials Data. (Luo J, Eldredge C, Cho CC, Cisler RA) JMIR Med Inform 2016 Oct 17;4(4):e30 PMID: 27751983 PMCID: PMC5088342 SCOPUS ID: 2-s2.0-85058013855 10/19/2016       17 Citations
  • Evaluating Acceptability and Efficacy of Antidepressant Medications using Patients Comments in Social Media (Zolnoori M, Patrick T, Conway M, Faiola A, Luo J) American Medical Informatics Association Annual Symposium 09/15/2016    
  • Big Data Application in Biomedical Research and Health Care: A Literature Review. (Luo J, Wu M, Gopukumar D, Zhao Y) Biomed Inform Insights 2016;8:1-10 PMID: 26843812 PMCID: PMC4720168 02/05/2016    
  • SimQ: real-time retrieval of similar consumer health questions. (Luo J, Zhang GQ, Wentz S, Cui L, Xu R) J Med Internet Res 2015 Feb 17;17(2):e43 PMID: 25689608 PMCID: PMC4376128 SCOPUS ID: 2-s2.0-84925611779 02/18/2015       13 Citations
  • Trial prospector: matching patients with cancer research studies using an automated and scalable approach. (Sahoo SS, Tao S, Parchman A, Luo Z, Cui L, Mergler P, Lanese R, Barnholtz-Sloan JS, Meropol NJ, Zhang GQ) Cancer Inform 2014;13:157-66 PMID: 25506198 PMCID: PMC4259509 SCOPUS ID: 2-s2.0-84919391508 12/17/2014       20 Citations
  • RMS: a platform for managing cross-disciplinary and multi-institutional research project collaboration. (Luo J, Apperson-Hansen C, Pelfrey CM, Zhang GQ) BMC Med Inform Decis Mak 2014 Nov 30;14:106 PMID: 25433526 PMCID: PMC4264263 SCOPUS ID: 2-s2.0-84964315895 12/01/2014    
  • Social Media and Big Data: Can tweet moods predict illness and hospital visits in a region? (Nambison P, Luo J, Kapoor A) APHA conference 141st Annual Meeting 11/14/2014    
  • Social Medical, Big Data and Public Health Informatics: Towards a Systematic Detection of Depression from Tweets (Nambison P, Luo Z, Patrick T, Cisler R) Hawaii International Conference on System Sciences 10/16/2014    
  • Multi-topic assignment for exploratory navigation of consumer health information in NetWellness using formal concept analysis. (Cui L, Xu R, Luo Z, Wentz S, Scarberry K, Zhang GQ) BMC Med Inform Decis Mak 2014 Aug 03;14:63 PMID: 25086916 PMCID: PMC4131492 SCOPUS ID: 2-s2.0-84906534500 08/05/2014       3 Citations
  • A residue-free green synergistic antifungal nanotechnology for pesticide thiram by ZnO nanoparticles. (Xue J, Luo Z, Li P, Ding Y, Cui Y, Wu Q) Sci Rep 2014 Jul 14;4:5408 PMID: 25023938 PMCID: PMC4097348 SCOPUS ID: 2-s2.0-84904489358 07/16/2014       69 Citations
  • Visualizing and evaluating the growth of multi-institutional collaboration based on research network analysis. (Luo J, Pelfrey C, Zhang GQ) AMIA Jt Summits Transl Sci Proc 2014;2014:60-6 PMID: 25954579 PMCID: PMC4419767 01/01/2014    
  • Mining patterns of adverse events using aggregated clinical trial results. (Luo Z, Zhang GQ, Xu R) AMIA Jt Summits Transl Sci Proc 2013;2013:112-6 PMID: 24303317 PMCID: PMC3814483 12/05/2013    
  • Semi-Automatic, Conjunctive Organization of Consumer Health Information in NetWellness Using UMLS and Formal Concept Analysis (Cui L, Luo Z, Wentz S, Scarberry K, Xu R, Zhang G-Q) AMIA Annual Symposium 11/14/2013    
  • Large-Scale Analysis of Serious Adverse Events Reporting in Clinical Trials Funded by For-Profit and Not-For-Profit Agencies (Luo Z, Zhang GQ, Teagno J, Xu R) AMIA Joint Summits on Translational Science 04/10/2013    
  • A human-computer collaborative approach to identifying common data elements in clinical trial eligibility criteria. (Luo Z, Miotto R, Weng C) J Biomed Inform 2013 Feb;46(1):33-9 PMID: 22846169 PMCID: PMC3524400 SCOPUS ID: 2-s2.0-84873106410 08/01/2012       32 Citations
  • Extracting temporal constraints from clinical research eligibility criteria using conditional random fields. (Luo Z, Johnson SB, Lai AM, Weng C) AMIA Annu Symp Proc 2011;2011:843-52 PMID: 22195142 PMCID: PMC3243135 SCOPUS ID: 2-s2.0-84874216479 12/24/2011       28 Citations
  • EliXR: an approach to eligibility criteria extraction and representation. (Weng C, Wu X, Luo Z, Boland MR, Theodoratos D, Johnson SB) J Am Med Inform Assoc 2011 Dec;18 Suppl 1(Suppl 1):i116-24 PMID: 21807647 PMCID: PMC3241167 SCOPUS ID: 2-s2.0-84863557848 08/03/2011       100 Citations
  • Dynamic categorization of clinical research eligibility criteria by hierarchical clustering. (Luo Z, Yetisgen-Yildiz M, Weng C) J Biomed Inform 2011 Dec;44(6):927-35 PMID: 21689783 PMCID: PMC3183114 SCOPUS ID: 2-s2.0-84855953110 06/22/2011       40 Citations
  • Corpus-based Approach to Creating a Semantic Lexicon for Clinical Research Eligibility Criteria from UMLS. (Luo Z, Duffy R, Johnson S, Weng C) Summit Transl Bioinform 2010 Mar 01;2010:26-30 PMID: 21347142 PMCID: PMC3041551 02/25/2011    
  • Semi-Automatically Inducing Semantic Classes of Clinical Research Eligibility Criteria Using UMLS and Hierarchical Clustering. (Luo Z, Johnson SB, Weng C) AMIA Annu Symp Proc 2010 Nov 13;2010:487-91 PMID: 21347026 PMCID: PMC3041461 SCOPUS ID: 2-s2.0-84964928019 02/25/2011       20 Citations
  • Multi-agent reinforcement learning–an exploration using Q-learning (Graham C, Bell D, Luo Z) Research and Development in Intelligent Systems XXVI 08/11/2010    
  • Incremental Knowledge Base for Uncertain Reasoning (Wu Q, Huang X, Bell DA, Qi G, Luo Z) Fuzzy Systems and Knowledge Discovery 05/15/2008    
  • Learning to select relevant perspective in a dynamic environment (Luo Z, Bell D, McCollum B, Wu Q) Neural Networks, 2008 IJCNN 2008(IEEE World Congress on Computational Intelligence) IEEE International Joint Conference 04/18/2008    
  • Discover Relevant Environment Feature Using Concurrent Reinforcement Learning (Luo Z, Bell DA, McCollum B) Twenty-Third Conference on Artificial Intelligence 04/17/2008    
  • Autonomous Robot Control Using Evidential Reasoning (Wu Q, Bell DA, Khokhar RH, Qi G, Luo Z) Fuzzy Systems and Knowledge Discovery 05/16/2007    
  • Skill combination for reinforcement learning. (Luo Z, Bell D, McCollum B) Intelligent Data Engineering and Automated Learning-IDEAL 04/13/2007    
  • Reinforcement Learning Sub-goal Discovery Using States Visited Statistic Method (Luo Z, Bell D, Wu Q) The 17th Irish conference on Artificial Intelligence and Cognitive Science (AICS) 04/12/2006    
    • Last update: 06/19/2024