Rainer G. Gedeit MD
Leadership Positions
Vice President and Chief Medical Officer, Children's WisconsinAdjunct Professor of PediatricsPublications (87)
Immunocompromised-Associated Pediatric Acute Respiratory Distress Syndrome: Experience From the 2016/2017 Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Prospective Cohort Study. (Gertz SJ, Bhalla A, Chima RS, Emeriaud G, Fitzgerald JC, Hsing DD, Jeyapalan AS, Pike F, Sallee CJ, Thomas NJ, Yehya N, Rowan CM, Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDIE) Investigators and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network) Pediatr Crit Care Med 2024 Apr 01;25(4):288-300 PMID: 38236083 PMCID: PMC10994753 SCOPUS ID: 2-s2.0-85190175695 01/18/2024 The Modified Clinical Progression Scale for Pediatric Patients: Evaluation as a Severity Metric and Outcome Measure in Severe Acute Viral Respiratory Illness. (Leland SB, Staffa SJ, Newhams MM, Khemani RG, Marshall JC, Young CC, Maddux AB, Hall MW, Weiss SL, Schwarz AJ, Coates BM, Sanders RC Jr, Kong M, Thomas NJ, Nofziger RA, Cullimore ML, Halasa NB, Loftis LL, Cvijanovich NZ, Schuster JE, Flori H, Gertz SJ, Hume JR, Olson SM, Patel MM, Zurakowski D, Randolph AG, Pediatric Acute Lung and Sepsis Investigator’s Network Pediatric Intensive Care Influenza Study Group (PALISI PICFLU) Investigators and Overcoming COVID-19 Investigators) Pediatr Crit Care Med 2023 Dec 01;24(12):998-1009 PMID: 37539964 PMCID: PMC10688559 SCOPUS ID: 2-s2.0-85179013325 08/04/2023 1 CitationTranscriptomic profiles of multiple organ dysfunction syndrome phenotypes in pediatric critical influenza. (Novak T, Crawford JC, Hahn G, Hall MW, Thair SA, Newhams MM, Chou J, Mourani PM, Tarquinio KM, Markovitz B, Loftis LL, Weiss SL, Higgerson R, Schwarz AJ, Pinto NP, Thomas NJ, Gedeit RG, Sanders RC Jr, Mahapatra S, Coates BM, Cvijanovich NZ, Ackerman KG, Tellez DW, McQuillen P, Kurachek SC, Shein SL, Lange C, Thomas PG, Randolph AG) Front Immunol 2023;14:1220028 PMID: 37533854 PMCID: PMC10390830 SCOPUS ID: 2-s2.0-85166427098 08/03/2023 1 CitationNoninvasive Ventilation for Pediatric Acute Respiratory Distress Syndrome: Experience From the 2016/2017 Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Prospective Cohort Study. (Emeriaud G, Pons-Òdena M, Bhalla AK, Shein SL, Killien EY, Modesto I Alapont V, Rowan C, Baudin F, Lin JC, Grégoire G, Napolitano N, Mayordomo-Colunga J, Diaz F, Cruces P, Medina A, Smith L, Khemani RG, Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDIE) Investigators and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network) Pediatr Crit Care Med 2023 Sep 01;24(9):715-726 PMID: 37255352 PMCID: PMC10524424 SCOPUS ID: 2-s2.0-85169848739 05/31/2023 9 CitationsDexmedetomidine for sedation during hematopoietic stem cell harvest apheresis and leukapheresis in the PICU: Guideline development. (Magner K, Mikhailov T, Simpson P, Anderson L, Buchman B, Gedeit R, Margolis D, Meyer MT) Transfus Apher Sci 2023 Feb;62(1):103525 PMID: 36058778 SCOPUS ID: 2-s2.0-85138530115 09/05/2022 "I Didn't Want My Baby to Pass, But I Didn't Want Him Suffering Either": Comparing Bereaved Parents' Narratives With Nursing End-of-Life Assessments in the Pediatric Intensive Care Unit. (Broden EG, Hinds PS, Werner-Lin AV, Curley MAQ,
for the
RESTORE
Study Investigators) J Hosp Palliat Nurs 2022 Oct 01;24(5):271-280 PMID: 35666188 PMCID: PMC9437116 SCOPUS ID: 2-s2.0-85137135680 06/07/2022 3 CitationsEarly Neuromuscular Blockade in Moderate-to-Severe Pediatric Acute Respiratory Distress Syndrome. (Rudolph MW, Kneyber MCJ, Asaro LA, Cheifetz IM, Wypij D, Curley MAQ,
for the Randomized Evaluation of Sedation Titration for Respiratory Failure (
RESTORE
) Study Investigators) Crit Care Med 2022 May 01;50(5):e445-e457 PMID: 35029869 SCOPUS ID: 2-s2.0-85129780110 01/15/2022 8 CitationsMechanical power in pediatric acute respiratory distress syndrome: a PARDIE study. (Bhalla AK, Klein MJ, Modesto I Alapont V, Emeriaud G, Kneyber MCJ, Medina A, Cruces P, Diaz F, Takeuchi M, Maddux AB, Mourani PM, Camilo C, White BR, Yehya N, Pappachan J, Di Nardo M, Shein S, Newth C, Khemani R, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network) Crit Care 2022 Jan 03;26(1):2 PMID: 34980228 PMCID: PMC8722295 SCOPUS ID: 2-s2.0-85123231433 01/05/2022 14 CitationsSchool and Work Absences After Critical Care Hospitalization for Pediatric Acute Respiratory Failure: A Secondary Analysis of a Cluster Randomized Trial. (Carlton EF, Donnelly JP, Prescott HC, Asaro LA, Barbaro RP, Watson RS, Curley MAQ, RESTORE Study Investigators) JAMA Netw Open 2021 Dec 01;4(12):e2140732 PMID: 34940862 PMCID: PMC8703244 SCOPUS ID: 2-s2.0-85122581115 12/24/2021 14 CitationsCompliance With an Antibiotic Guideline for Suspected Ventilator-Associated Infection: The Ventilator-Associated INfection (VAIN2) Study (Karsies T, Tarquinio K, Shein S, Beardsley A, Prentice E, Karam O, Fontela P, Moore-Clingenpeel M, Willson D, Pediatric Acute Lung Injury and Sepsis Investigator’s (PALISI) Network (RGEDEIT)) Pediatric Critical Care Medicine Pediatric Critical Care Medicine: October 2021 - Volume 22 - Issue 10 - p 859-869 doi: 10.1097/PCC.0000000000002761 10/01/2021 Epidemiology and Outcomes of Critically Ill Children at Risk for Pediatric Acute Respiratory Distress Syndrome: A Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Study. (Shein SL, Maddux AB, Klein MJ, Bhalla A, Briassoulis G, Dahmer MK, Emeriaud G, Flori HR, Gedeit R, Ilia S, Kneyber MCJ, Napolitano N, Ohshimo S, Pons-Òdena M, Rubin S, White BR, Yehya N, Khemani R, Smith L, V4 PARDIE Investigators and the PALISI Network) Crit Care Med 2022 Mar 01;50(3):363-374 PMID: 34582416 SCOPUS ID: 2-s2.0-85125014374 09/29/2021 10 CitationsIncome-driven socioeconomic status and presenting illness severity in children with acute respiratory failure. (Kachmar AG, Wypij D, Perry MA, Curley MAQ, RESTORE Study Investigators) Res Nurs Health 2021 Dec;44(6):920-930 PMID: 34505720 PMCID: PMC8559130 SCOPUS ID: 2-s2.0-85114738143 09/11/2021 3 CitationsAssociation of Socioeconomic Status With Postdischarge Pediatric Resource Use and Quality of Life. (Kachmar AG, Watson RS, Wypij D, Perry MA, Curley MAQ,
for the Randomized Evaluation of Sedation Titration for Respiratory Failure (
RESTORE
) Investigative Team) Crit Care Med 2022 Feb 01;50(2):e117-e128 PMID: 34495879 PMCID: PMC8810731 SCOPUS ID: 2-s2.0-85123970002 09/09/2021 6 CitationsAdherence to Lung-Protective Ventilation Principles in Pediatric Acute Respiratory Distress Syndrome: A Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Study. (Bhalla AK, Klein MJ, Emeriaud G, Lopez-Fernandez YM, Napolitano N, Fernandez A, Al-Subu AM, Gedeit R, Shein SL, Nofziger R, Hsing DD, Briassoulis G, Ilia S, Baudin F, Piñeres-Olave BE, Maria Izquierdo L, Lin JC, Cheifetz IM, Kneyber MCJ, Smith L, Khemani RG, Newth CJL, Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDIE) V.2. Investigators and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network) Crit Care Med 2021 Oct 01;49(10):1779-1789 PMID: 34259438 PMCID: PMC8448899 SCOPUS ID: 2-s2.0-85115909202 07/15/2021 24 CitationsThe Impact of Preintubation Noninvasive Ventilation on Outcomes in Pediatric Acute Respiratory Distress Syndrome. (Kopp W, Gedeit RG, Asaro LA, McLaughlin GE, Wypij D, Curley MAQ, Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) Study Investigators) Crit Care Med 2021 May 01;49(5):816-827 PMID: 33590999 SCOPUS ID: 2-s2.0-85104370095 02/17/2021 15 CitationsDevelopment of a Standardized Clinical Assessment and Management Plan for Pediatric Acute Respiratory Distress Syndrome (Rajapreyar P, Andres J, Pano C, O'Brien K, Matuszak A, McDermott K, Powell M, Murkowski K, Kasch M, Hay S, Petersen T, Gedeit R, Wakeham M ) Journal of Pediatric Intensive Care J Pediatr Intensive Care DOI: 10.1055/s-0040-1721724 01/04/2021 Development of a Standardized Clinical Assessment and Management Plan for Pediatric Acute Respiratory Distress Syndrome. (Rajapreyar P, Andres J, Pano C, O'Brien K, Matuszak A, McDermott K, Powell M, Murkowski K, Kasch M, Hay S, Petersen TL, Gedeit R, Wakeham M) J Pediatr Intensive Care 2022 Sep;11(3):193-200 PMID: 35928037 PMCID: PMC9345670 01/04/2021 Publisher Correction: Exuberant fibroblast activity compromises lung function via ADAMTS4. (Boyd DF, Allen EK, Randolph AG, Guo XJ, Weng Y, Sanders CJ, Bajracharya R, Lee NK, Guy CS, Vogel P, Guan W, Li Y, Liu X, Novak T, Newhams MM, Fabrizio TP, Wohlgemuth N, Mourani PM, PALISI Pediatric Intensive Care Influenza (PICFLU) Investigators, Wight TN, Schultz-Cherry S, Cormier SA, Shaw-Saliba K, Pekosz A, Rothman RE, Chen KF, Yang Z, Webby RJ, Zhong N, Crawford JC, Thomas PG) Nature 2020 Dec;588(7836):E5 PMID: 33208953 SCOPUS ID: 2-s2.0-85096321716 11/20/2020 2 CitationsExuberant fibroblast activity compromises lung function via ADAMTS4. (Boyd DF, Allen EK, Randolph AG, Guo XJ, Weng Y, Sanders CJ, Bajracharya R, Lee NK, Guy CS, Vogel P, Guan W, Li Y, Liu X, Novak T, Newhams MM, Fabrizio TP, Wohlgemuth N, Mourani PM, PALISI Pediatric Intensive Care Influenza (PICFLU) Investigators, Wight TN, Schultz-Cherry S, Cormier SA, Shaw-Saliba K, Pekosz A, Rothman RE, Chen KF, Yang Z, Webby RJ, Zhong N, Crawford JC, Thomas PG) Nature 2020 Nov;587(7834):466-471 PMID: 33116313 PMCID: PMC7883627 SCOPUS ID: 2-s2.0-85094679147 10/30/2020 86 CitationsAssociation of Race and Ethnicity with Sedation Management in Pediatric Intensive Care. (Natale JE, Asaro LA, Joseph JG, Ulysse C, Ascenzi J, Bowens C, Wypij D, Curley MAQ, RESTORE Study Investigators) Ann Am Thorac Soc 2021 Jan;18(1):93-102 PMID: 32776853 PMCID: PMC7780975 SCOPUS ID: 2-s2.0-85098733126 08/11/2020 4 CitationsPrognostic relevance and inter-observer reliability of chest-imaging in pediatric ARDS: a pediatric acute respiratory distress incidence and epidemiology (PARDIE) study. (López-Fernández YM, Smith LS, Kohne JG, Weinman JP, Modesto-Alapont V, Reyes-Dominguez SB, Medina A, Piñeres-Olave BE, Mahieu N, Klein MJ, Flori HR, Jouvet P, Khemani RG, Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDIE) V3 Investigators and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network) Intensive Care Med 2020 Jul;46(7):1382-1393 PMID: 32451578 PMCID: PMC7246298 SCOPUS ID: 2-s2.0-85085396623 05/27/2020 17 CitationsPredicting Mortality in Children With Pediatric Acute Respiratory Distress Syndrome: A Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Study. (Yehya N, Harhay MO, Klein MJ, Shein SL, Piñeres-Olave BE, Izquierdo L, Sapru A, Emeriaud G, Spinella PC, Flori HR, Dahmer MK, Maddux AB, Lopez-Fernandez YM, Haileselassie B, Hsing DD, Chima RS, Hassinger AB, Valentine SL, Rowan CM, Kneyber MCJ, Smith LS, Khemani RG, Thomas NJ, Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDIE) V1 Investigators and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network) Crit Care Med 2020 Jun;48(6):e514-e522 PMID: 32271186 PMCID: PMC7237024 SCOPUS ID: 2-s2.0-85085159643 04/10/2020 31 CitationsEarly Use of Adjunctive Therapies for Pediatric Acute Respiratory Distress Syndrome: A PARDIE Study. (Rowan CM, Klein MJ, Hsing DD, Dahmer MK, Spinella PC, Emeriaud G, Hassinger AB, Piñeres-Olave BE, Flori HR, Haileselassie B, Lopez-Fernandez YM, Chima RS, Shein SL, Maddux AB, Lillie J, Izquierdo L, Kneyber MCJ, Smith LS, Khemani RG, Thomas NJ, Yehya N) Am J Respir Crit Care Med 2020 Jun 01;201(11):1389-1397 PMID: 32130867 PMCID: PMC7258654 SCOPUS ID: 2-s2.0-85085905075 03/05/2020 32 CitationsRIG-I and TLR4 responses and adverse outcomes in pediatric influenza-related critical illness. (Novak T, Hall MW, McDonald DR, Newhams MM, Mistry AJ, Panoskaltsis-Mortari A, Mourani PM, Loftis LL, Weiss SL, Tarquinio KM, Markovitz B, Hartman ME, Schwarz A, Junger WG, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators) J Allergy Clin Immunol 2020 Jun;145(6):1673-1680.e11 PMID: 32035159 PMCID: PMC7323584 SCOPUS ID: 2-s2.0-85081281320 02/09/2020 16 CitationsDevelopment of an Antibiotic Guideline for Children With Suspected Ventilator-Associated Infections. (Shein SL, Karam O, Beardsley A, Karsies T, Prentice E, Tarquinio KM, Willson DF, Pediatric Acute Lung Injury and Sepsis Investigator (PALISI) Network) Pediatr Crit Care Med 2019 Aug;20(8):697-706 PMID: 30985606 SCOPUS ID: 2-s2.0-85071348420 04/16/2019 7 CitationsFailure of Clinical Trials in Pediatric Respiratory Failure: Can We Blame Endotypes? (Gedeit RG) Pediatr Crit Care Med 2019 Feb;20(2):187-188 PMID: 30720648 SCOPUS ID: 2-s2.0-85061049268 02/06/2019 Correction to: Methods in the design and implementation of the Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) clinical trial. (Curley MAQ, Gedeit RG, Dodson BL, Amling JK, Soetenga DJ, Corriveau CO, Asaro LA, Wypij D, RESTORE Investigative Team) Trials 2019 Jan 07;20(1):17 PMID: 30616620 PMCID: PMC6323764 SCOPUS ID: 2-s2.0-85059680353 01/09/2019 1 CitationMethods in the design and implementation of the Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) clinical trial. (Curley MAQ, Gedeit RG, Dodson BL, Amling JK, Soetenga DJ, Corriveau CO, Asario LA, Wypij D, RESTORE Investigative Team) Trials 2018 Dec 17;19(1):687 PMID: 30558653 PMCID: PMC6296093 SCOPUS ID: 2-s2.0-85058680847 12/19/2018 9 CitationsSedation Management for Critically Ill Children with Pre-Existing Cognitive Impairment. (Best KM, Asaro LA, Curley MAQ, Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) Study Investigators) J Pediatr 2019 Mar;206:204-211.e1 PMID: 30527750 PMCID: PMC6389364 SCOPUS ID: 2-s2.0-85057787430 12/12/2018 4 CitationsPaediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study. (Khemani RG, Smith L, Lopez-Fernandez YM, Kwok J, Morzov R, Klein MJ, Yehya N, Willson D, Kneyber MCJ, Lillie J, Fernandez A, Newth CJL, Jouvet P, Thomas NJ, Pediatric Acute Respiratory Distress syndrome Incidence and Epidemiology (PARDIE) Investigators, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network) Lancet Respir Med 2019 Feb;7(2):115-128 PMID: 30361119 PMCID: PMC7045907 SCOPUS ID: 2-s2.0-85055089832 10/27/2018 236 CitationsHyperchloremia is associated with acute kidney injury in pediatric patients with septic shock. (Stenson EK, Cvijanovich NZ, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Jain PN, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Lutfi R, Gertz S, Grunwell JR, Wong HR, Anas N) Intensive Care Med 2018 Nov;44(11):2004-2005 PMID: 30324289 SCOPUS ID: 2-s2.0-85056400911 10/17/2018 12 CitationsVancomycin Monotherapy May Be Insufficient to Treat Methicillin-resistant Staphylococcus aureus Coinfection in Children With Influenza-related Critical Illness. (Randolph AG, Xu R, Novak T, Newhams MM, Bubeck Wardenburg J, Weiss SL, Sanders RC, Thomas NJ, Hall MW, Tarquinio KM, Cvijanovich N, Gedeit RG, Truemper EJ, Markovitz B, Hartman ME, Ackerman KG, Giuliano JS Jr, Shein SL, Moffitt KL, Pediatric Intensive Care Influenza Investigators from the Pediatric Acute Lung Injury and Sepsis Investigator’s Network) Clin Infect Dis 2019 Jan 18;68(3):365-372 PMID: 29893805 PMCID: PMC6336914 SCOPUS ID: 2-s2.0-85060176384 06/13/2018 30 CitationsHyperchloremia Is Associated With Complicated Course and Mortality in Pediatric Patients With Septic Shock. (Stenson EK, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Grunwell JR, Wong HR) Pediatr Crit Care Med 2018 Feb;19(2):155-160 PMID: 29394222 PMCID: PMC5798001 SCOPUS ID: 2-s2.0-85048385897 02/03/2018 56 CitationsDoes Extracorporeal Membrane Oxygenation Improve Survival in Pediatric Acute Respiratory Failure? (Barbaro RP, Xu Y, Borasino S, Truemper EJ, Watson RS, Thiagarajan RR, Wypij D, Curley MAQ, RESTORE Study Investigators *) Am J Respir Crit Care Med 2018 May 01;197(9):1177-1186 PMID: 29373797 PMCID: PMC6019927 SCOPUS ID: 2-s2.0-85046537078 01/27/2018 41 CitationsLong-Term Outcomes after Protocolized Sedation versus Usual Care in Ventilated Pediatric Patients. (Watson RS, Asaro LA, Hertzog JH, Sorce LR, Kachmar AG, Dervan LA, Angus DC, Wypij D, Curley MAQ, RESTORE Study Investigators and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network) Am J Respir Crit Care Med 2018 Jun 01;197(11):1457-1467 PMID: 29313710 PMCID: PMC6005554 SCOPUS ID: 2-s2.0-85048143721 01/10/2018 54 CitationsEndotype Transitions During the Acute Phase of Pediatric Septic Shock Reflect Changing Risk and Treatment Response. (Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Lutfi R, Gertz S, Grunwell JR, Lindsell CJ) Crit Care Med 2018 Mar;46(3):e242-e249 PMID: 29252929 PMCID: PMC5825261 SCOPUS ID: 2-s2.0-85051091373 12/19/2017 40 CitationsCytokine Profiles of Severe Influenza Virus-Related Complications in Children. (Fiore-Gartland A, Panoskaltsis-Mortari A, Agan AA, Mistry AJ, Thomas PG, Matthay MA, PALISI PICFlu Investigators, Hertz T, Randolph AG) Front Immunol 2017;8:1423 PMID: 29163498 PMCID: PMC5681736 SCOPUS ID: 2-s2.0-85034090505 11/23/2017 31 CitationsSedation Management in Children Supported on Extracorporeal Membrane Oxygenation for Acute Respiratory Failure. (Schneider JB, Sweberg T, Asaro LA, Kirby A, Wypij D, Thiagarajan RR, Curley MAQ, Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) Study Investigators) Crit Care Med 2017 Oct;45(10):e1001-e1010 PMID: 28614197 PMCID: PMC5600656 SCOPUS ID: 2-s2.0-85020720505 06/15/2017 19 CitationsEvaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection. (Randolph AG, Yip WK, Allen EK, Rosenberger CM, Agan AA, Ash SA, Zhang Y, Bhangale TR, Finkelstein D, Cvijanovich NZ, Mourani PM, Hall MW, Su HC, Thomas PG, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Pediatric Influenza (PICFLU) Investigators, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Pediatric Influenza (PICFLU) Investigators) J Infect Dis 2017 Jul 01;216(1):14-21 PMID: 28531322 PMCID: PMC5853450 SCOPUS ID: 2-s2.0-85024473634 05/23/2017 44 CitationsRacial and Ethnic Disparities in Parental Refusal of Consent in a Large, Multisite Pediatric Critical Care Clinical Trial. (Natale JE, Lebet R, Joseph JG, Ulysse C, Ascenzi J, Wypij D, Curley MAQ, Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) Study Investigators) J Pediatr 2017 May;184:204-208.e1 PMID: 28410087 SCOPUS ID: 2-s2.0-85018465706 04/15/2017 27 CitationsImproved Risk Stratification in Pediatric Septic Shock Using Both Protein and mRNA Biomarkers. PERSEVERE-XP. (Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Grunwell JR, Lindsell CJ) Am J Respir Crit Care Med 2017 Aug 15;196(4):494-501 PMID: 28324661 PMCID: PMC5564676 SCOPUS ID: 2-s2.0-85028608785 03/23/2017 47 CitationsThe authors reply. (Faustino EV, Gedeit RG, Schwarz A, Asaro LA, Wypij D, Curley MA) Crit Care Med 2017 Mar;45(3):e333-e334 PMID: 28212236 PMCID: PMC5319485 SCOPUS ID: 2-s2.0-85013469098 02/18/2017 Multiple Organ Dysfunction in Children Mechanically Ventilated for Acute Respiratory Failure. (Weiss SL, Asaro LA, Flori HR, Allen GL, Wypij D, Curley MA, Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) Study Investigators) Pediatr Crit Care Med 2017 Apr;18(4):319-329 PMID: 28212163 PMCID: PMC5380520 SCOPUS ID: 2-s2.0-85013080231 02/18/2017 29 CitationsGlucocorticoid Receptor Polymorphisms and Outcomes in Pediatric Septic Shock. (Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald J, Checchia PA, Meyer K, Quasney M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Grunwell JR, Opoka A, Wong HR) Pediatr Crit Care Med 2017 Apr;18(4):299-303 PMID: 28178077 PMCID: PMC5380529 SCOPUS ID: 2-s2.0-85011818910 02/09/2017 12 CitationsPediatric Ventilator-Associated Infections: The Ventilator-Associated INfection Study. (Willson DF, Hoot M, Khemani R, Carrol C, Kirby A, Schwarz A, Gedeit R, Nett ST, Erickson S, Flori H, Hays S, Hall M, Ventilator-Associated INfection (VAIN) Investigators and the Pediatric Acute Lung Injury and Sepsis Investigator’s (PALISI) Network) Pediatr Crit Care Med 2017 Jan;18(1):e24-e34 PMID: 27828898 SCOPUS ID: 2-s2.0-84994589661 11/10/2016 22 CitationsPediatric Sepsis Biomarker Risk Model-II: Redefining the Pediatric Sepsis Biomarker Risk Model With Septic Shock Phenotype. (Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald J, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Howard K, Harmon K, Lahni P, Frank E, Hart KW, Nguyen TC, Lindsell CJ) Crit Care Med 2016 Nov;44(11):2010-2017 PMID: 27513537 PMCID: PMC5201138 SCOPUS ID: 2-s2.0-84991643950 10/19/2016 75 CitationsDexmedetomidine Use in Critically Ill Children With Acute Respiratory Failure. (Grant MJ, Schneider JB, Asaro LA, Dodson BL, Hall BA, Simone SL, Cowl AS, Munkwitz MM, Wypij D, Curley MA, Randomized Evaluation of Sedation Titration for Respiratory Failure Study Investigators) Pediatr Crit Care Med 2016 Dec;17(12):1131-1141 PMID: 27654816 PMCID: PMC5138139 SCOPUS ID: 2-s2.0-84988589043 09/23/2016 60 CitationsStaphylococcus aureus α-Toxin Response Distinguishes Respiratory Virus-Methicillin-Resistant S. aureus Coinfection in Children. (Yu KO, Randolph AG, Agan AA, Yip WK, Truemper EJ, Weiss SL, Ackerman KG, Schwarz AJ, Giuliano JS Jr, Hall MW, Bubeck Wardenburg J, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) PICFlu Study Group, PALISI PICFlu Study Group) J Infect Dis 2016 Dec 01;214(11):1638-1646 PMID: 27651418 PMCID: PMC5144732 SCOPUS ID: 2-s2.0-85014660072 09/22/2016 15 CitationsAccuracy of an Extubation Readiness Test in Predicting Successful Extubation in Children With Acute Respiratory Failure From Lower Respiratory Tract Disease. (Faustino EV, Gedeit R, Schwarz AJ, Asaro LA, Wypij D, Curley MA, Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) Study Investigators) Crit Care Med 2017 Jan;45(1):94-102 PMID: 27632676 PMCID: PMC5541896 SCOPUS ID: 2-s2.0-84987904678 09/16/2016 39 CitationsPatient, Process, and System Predictors of Iatrogenic Withdrawal Syndrome in Critically Ill Children. (Best KM, Wypij D, Asaro LA, Curley MA, Randomized Evaluation of Sedation Titration For Respiratory Failure Study Investigators) Crit Care Med 2017 Jan;45(1):e7-e15 PMID: 27513532 SCOPUS ID: 2-s2.0-85006421928 08/12/2016 49 CitationsHereditary angioedema presenting as compartment syndrome in a white girl. (Chen WL, Gallagher J, Zafra H, Gedeit R) Ann Allergy Asthma Immunol 2016 Sep;117(3):321-2 PMID: 27397069 SCOPUS ID: 2-s2.0-84996565810 07/12/2016 3 CitationsCombining Prognostic and Predictive Enrichment Strategies to Identify Children With Septic Shock Responsive to Corticosteroids. (Wong HR, Atkinson SJ, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald JC, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Lindsell CJ) Crit Care Med 2016 Oct;44(10):e1000-3 PMID: 27270179 PMCID: PMC5026540 SCOPUS ID: 2-s2.0-84973375389 06/09/2016 89 CitationsThe Association of Central-Line-Associated Bloodstream Infections With Central-Line Utilization Rate and Maintenance Bundle Compliance Among Types of PICUs. (Affolter JT, Huskins WC, Moss M, Kuhn EM, Gedeit R, Rice TB) Pediatr Crit Care Med 2016 Jul;17(7):591-7 PMID: 27124562 SCOPUS ID: 2-s2.0-84979022727 04/29/2016 4 CitationsFamily Presence During Pediatric Tracheal Intubations. (Sanders RC Jr, Nett ST, Davis KF, Parker MM, Bysani GK, Adu-Darko M, Bird GL, Cheifetz IM, Derbyshire AT, Emeriaud G, Giuliano JS Jr, Graciano AL, Hagiwara Y, Hefley G, Ikeyama T, Jarvis JD, Kamat P, Krishna AS, Lee A, Lee JH, Li S, Meyer K, Montgomery VL, Nagai Y, Pinto M, Rehder KJ, Saito O, Shenoi AN, Taekema HC, Tarquinio KM, Thompson AE, Turner DA, Nadkarni VM, Nishisaki A, National Emergency Airway Registry for Children NEAR4KIDS Investigators, Pediatric Acute Lung Injury and Sepsis Investigators Network) JAMA Pediatr 2016 Mar;170(3):e154627 PMID: 26954533 SCOPUS ID: 2-s2.0-84962393708 03/10/2016 20 CitationsOptimizing Virus Identification in Critically Ill Children Suspected of Having an Acute Severe Viral Infection. (Randolph AG, Agan AA, Flanagan RF, Meece JK, Fitzgerald JC, Loftis LL, Truemper EJ, Li S, Ferdinands JM, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) PICFlu Study Group) Pediatr Crit Care Med 2016 Apr;17(4):279-86 PMID: 26895562 SCOPUS ID: 2-s2.0-84958811690 02/20/2016 11 CitationsProspective Testing and Redesign of a Temporal Biomarker Based Risk Model for Patients With Septic Shock: Implications for Septic Shock Biology. (Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald J, Checchia PA, Meyer K, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Howard K, Harmon K, Lahni P, Frank E, Hart KW, Lindsell CJ) EBioMedicine 2015 Dec;2(12):2087-93 PMID: 26844289 PMCID: PMC4703723 SCOPUS ID: 2-s2.0-84958836185 02/05/2016 10 Citations767: CHLORHEXIDINE TREATMENTS AS AN ADJUNCT TO A COMPREHENSIVE PROGRAM FOR REDUCTION OF CLABSI IN A PICU. (Gedeit R, Braby J, Redfern W, Rotar M) Crit Care Med 2015 Dec;43(12 Suppl 1):193 PMID: 26570428 11/17/2015 Early High-Frequency Oscillatory Ventilation in Pediatric Acute Respiratory Failure. A Propensity Score Analysis. (Bateman ST, Borasino S, Asaro LA, Cheifetz IM, Diane S, Wypij D, Curley MA, RESTORE Study Investigators) Am J Respir Crit Care Med 2016 Mar 01;193(5):495-503 PMID: 26492410 PMCID: PMC4824923 SCOPUS ID: 2-s2.0-84988876269 10/23/2015 76 CitationsA Multibiomarker-Based Model for Estimating the Risk of Septic Acute Kidney Injury. (Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald J, Checchia PA, Meyer K, Shanley TP, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Dawson E, Howard K, Harmon K, Lahni P, Frank E, Hart KW, Lindsell CJ) Crit Care Med 2015 Aug;43(8):1646-53 PMID: 25962083 PMCID: PMC4667777 SCOPUS ID: 2-s2.0-84942509173 05/12/2015 25 CitationsProtocolized sedation vs usual care in pediatric patients mechanically ventilated for acute respiratory failure: a randomized clinical trial. (Curley MA, Wypij D, Watson RS, Grant MJ, Asaro LA, Cheifetz IM, Dodson BL, Franck LS, Gedeit RG, Angus DC, Matthay MA, RESTORE Study Investigators and the Pediatric Acute Lung Injury and Sepsis Investigators Network) JAMA 2015 Jan 27;313(4):379-89 PMID: 25602358 PMCID: PMC4955566 SCOPUS ID: 2-s2.0-84921788453 01/21/2015 311 CitationsComparative effectiveness of intravenous vs oral antibiotics for postdischarge treatment of acute osteomyelitis in children. (Keren R, Shah SS, Srivastava R, Rangel S, Bendel-Stenzel M, Harik N, Hartley J, Lopez M, Seguias L, Tieder J, Bryan M, Gong W, Hall M, Localio R, Luan X, deBerardinis R, Parker A, Pediatric Research in Inpatient Settings Network) JAMA Pediatr 2015 Feb;169(2):120-8 PMID: 25506733 SCOPUS ID: 2-s2.0-84964266013 12/17/2014 155 CitationsDeveloping a clinically feasible personalized medicine approach to pediatric septic shock. (Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald J, Checchia PA, Meyer K, Shanley TP, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Shekhar RS, Gertz S, Dawson E, Howard K, Harmon K, Beckman E, Frank E, Lindsell CJ) Am J Respir Crit Care Med 2015 Feb 01;191(3):309-15 PMID: 25489881 PMCID: PMC4351580 SCOPUS ID: 2-s2.0-84922311029 12/10/2014 214 CitationsVariability in IRBs regarding parental acceptance of passive consent. (Higgerson RA, Olsho LE, Christie LM, Rehder K, Doksum T, Gedeit R, Giuliano JS Jr, Brennan B, Wendlandt R, Randolph AG, PALISI PICFlu Study Investigators) Pediatrics 2014 Aug;134(2):e496-503 PMID: 25002659 SCOPUS ID: 2-s2.0-84905276157 07/09/2014 10 CitationsEffectiveness of influenza vaccine against life-threatening RT-PCR-confirmed influenza illness in US children, 2010-2012. (Ferdinands JM, Olsho LE, Agan AA, Bhat N, Sullivan RM, Hall M, Mourani PM, Thompson M, Randolph AG, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network) J Infect Dis 2014 Sep 01;210(5):674-83 PMID: 24676207 SCOPUS ID: 2-s2.0-84903198668 03/29/2014 116 CitationsThe temporal version of the pediatric sepsis biomarker risk model. (Wong HR, Weiss SL, Giuliano JS Jr, Wainwright MS, Cvijanovich NZ, Thomas NJ, Allen GL, Anas N, Bigham MT, Hall M, Freishtat RJ, Sen A, Meyer K, Checchia PA, Shanley TP, Nowak J, Quasney M, Chopra A, Fitzgerald JC, Gedeit R, Banschbach S, Beckman E, Harmon K, Lahni P, Lindsell CJ) PLoS One 2014;9(3):e92121 PMID: 24626215 PMCID: PMC3953585 SCOPUS ID: 2-s2.0-84898013136 03/15/2014 32 CitationsTesting the prognostic accuracy of the updated pediatric sepsis biomarker risk model. (Wong HR, Weiss SL, Giuliano JS Jr, Wainwright MS, Cvijanovich NZ, Thomas NJ, Allen GL, Anas N, Bigham MT, Hall M, Freishtat RJ, Sen A, Meyer K, Checchia PA, Shanley TP, Nowak J, Quasney M, Chopra A, Fitzgerald JC, Gedeit R, Banschbach S, Beckman E, Lahni P, Hart K, Lindsell CJ) PLoS One 2014;9(1):e86242 PMID: 24489704 PMCID: PMC3906040 SCOPUS ID: 2-s2.0-84897378910 02/04/2014 67 CitationsRelationship between caloric intake and length of hospital stay for infants with bronchiolitis. (Weisgerber MC, Lye PS, Nugent M, Li SH, De Fouw K, Gedeit R, Simpson P, Gorelick MH) Hosp Pediatr 2013 Jan;3(1):24-30 PMID: 24319832 12/11/2013 Asthma, steroids, and surveys…science or merely my opinion? (Gedeit RG) Pediatr Crit Care Med 2013 Jun;14(5):544-5 PMID: 23867433 SCOPUS ID: 2-s2.0-84895932656 07/23/2013 Defining sedation-related adverse events in the pediatric intensive care unit. (Grant MJ, Balas MC, Curley MA, RESTORE Investigative Team) Heart Lung 2013;42(3):171-6 PMID: 23643411 PMCID: PMC3641854 SCOPUS ID: 2-s2.0-84877145437 05/07/2013 25 CitationsCritically ill children during the 2009-2010 influenza pandemic in the United States. (Randolph AG, Vaughn F, Sullivan R, Rubinson L, Thompson BT, Yoon G, Smoot E, Rice TW, Loftis LL, Helfaer M, Doctor A, Paden M, Flori H, Babbitt C, Graciano AL, Gedeit R, Sanders RC, Giuliano JS, Zimmerman J, Uyeki TM, Pediatric Acute Lung Injury and Sepsis Investigator's Network and the National Heart, Lung, and Blood Institute ARDS Clinical Trials Network) Pediatrics 2011 Dec;128(6):e1450-8 PMID: 22065262 PMCID: PMC3387899 SCOPUS ID: 2-s2.0-83155173349 11/09/2011 181 CitationsFactors predicting prolonged hospital stay for infants with bronchiolitis. (Weisgerber MC, Lye PS, Li SH, Bakalarski D, Gedeit R, Simpson P, Gorelick MH) J Hosp Med 2011 May;6(5):264-70 PMID: 21661099 SCOPUS ID: 2-s2.0-79958719368 06/11/2011 25 CitationsU.S. attitudes and perceived practice for noninvasive ventilation in pediatric acute respiratory failure. (Fanning JJ, Lee KJ, Bragg DS, Gedeit RG) Pediatr Crit Care Med 2011 Sep;12(5):e187-94 PMID: 20921916 SCOPUS ID: 2-s2.0-80455174224 10/06/2010 7 CitationsAnemia, blood loss, and blood transfusions in North American children in the intensive care unit. (Bateman ST, Lacroix J, Boven K, Forbes P, Barton R, Thomas NJ, Jacobs B, Markovitz B, Goldstein B, Hanson JH, Li HA, Randolph AG, Pediatric Acute Lung Injury and Sepsis Investigators Network) Am J Respir Crit Care Med 2008 Jul 01;178(1):26-33 PMID: 18420962 SCOPUS ID: 2-s2.0-46349095109 04/19/2008 219 CitationsCumulative fluid intake minus output is not associated with ventilator weaning duration or extubation outcomes in children. (Randolph AG, Forbes PW, Gedeit RG, Arnold JH, Wetzel RC, Luckett PM, O'Neil ME, Venkataraman ST, Meert KL, Cheifetz IM, Cox PN, Hanson JH, Pediatric Acute Lung Injury & Sepsis Investigators (PALISI) Network) Pediatr Crit Care Med 2005 Nov;6(6):642-7 PMID: 16276328 SCOPUS ID: 2-s2.0-27844511944 11/09/2005 46 CitationsThe patient died, but we can try again: simulation in pediatric critical care training. (Gedeit R) Pediatr Crit Care Med 2005 Nov;6(6):712-3 PMID: 16276341 SCOPUS ID: 2-s2.0-27844561467 11/09/2005 4 CitationsCumulative fluid intake minus output is not associated with ventilator weaning duration or extubation outcomes in children (Randolph AG, Forbes PW, Gedeit RG, Arnold JH, Wetzel RC, Luckett PM, O'Neil ME, Venkataraman ST, Meert KL, Cheifetz IM, Cox PN, Hanson JH) Pediatric Critical Care Medicine November 2005;6(6) SCOPUS ID: 2-s2.0-27844511944 01/01/2005 46 CitationsAll roses are flowers, but not all flowers are roses. (Venkataraman S, Randolph A, Hanson J, Forbes P, Cheifetz I, Gedeit R, Luckett P) Am J Respir Crit Care Med 2004 Apr 15;169(8):969 PMID: 15072986 SCOPUS ID: 2-s2.0-1842555271 04/10/2004 The feasibility of conducting clinical trials in infants and children with acute respiratory failure. (Randolph AG, Meert KL, O'Neil ME, Hanson JH, Luckett PM, Arnold JH, Gedeit RG, Cox PN, Roberts JS, Venkataraman ST, Forbes PW, Cheifetz IM, Pediatric Acute Lung Injury and Sepsis Investigators Network) Am J Respir Crit Care Med 2003 May 15;167(10):1334-40 PMID: 12615617 SCOPUS ID: 2-s2.0-0038628989 03/05/2003 152 CitationsEffect of mechanical ventilator weaning protocols on respiratory outcomes in infants and children: a randomized controlled trial. (Randolph AG, Wypij D, Venkataraman ST, Hanson JH, Gedeit RG, Meert KL, Luckett PM, Forbes P, Lilley M, Thompson J, Cheifetz IM, Hibberd P, Wetzel R, Cox PN, Arnold JH, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network) JAMA 2002 Nov 27;288(20):2561-8 PMID: 12444863 SCOPUS ID: 2-s2.0-0037184417 11/28/2002 333 CitationsMedical management of the shaken infant (Gedeit RG) Journal of Aggression, Maltreatment and Trauma 2001;5(1):155-171 SCOPUS ID: 2-s2.0-0035182557 12/10/2001 3 CitationsA workshop to teach and evaluate medical students' altruism. (Gedeit R, Murkowski K, Miller S) Acad Med 2001 May;76(5):506 PMID: 11346541 SCOPUS ID: 2-s2.0-0035348557 05/11/2001 2 CitationsHead injury. (Gedeit R) Pediatr Rev 2001 Apr;22(4):118-24 PMID: 11283324 SCOPUS ID: 2-s2.0-0035696362 04/03/2001 20 CitationsLiquid ventilation. (Day SE, Gedeit RG) Clin Perinatol 1998 Sep;25(3):711-22 PMID: 9779343 SCOPUS ID: 2-s2.0-0031688253 10/21/1998 11 CitationsFailure of aggressive therapy to alter outcome in pediatric near-drowning. (Spack L, Gedeit R, Splaingard M, Havens PL) Pediatr Emerg Care 1997 Apr;13(2):98-102 PMID: 9127416 SCOPUS ID: 2-s2.0-0030943372 04/01/1997 40 CitationsTumor necrosis factor-induced E-selectin expression on vascular endothelial cells. (Gedeit RG) Crit Care Med 1996 Sep;24(9):1543-6 PMID: 8797629 SCOPUS ID: 2-s2.0-0029832409 09/01/1996 16 CitationsControl and variability of gastric pH in critically ill children. (Gedeit RG, Weigle CG, Havens PL, Werlin SL) Crit Care Med 1993 Dec;21(12):1850-5 PMID: 8252889 SCOPUS ID: 2-s2.0-0027494243 12/01/1993 21 CitationsThe role of MRI in evaluation of an adolescent with a pelvic mass. (Gedeit RG, Jay MS, Ros SP) J Adolesc Health Care 1990 Nov;11(6):516-8 PMID: 2262399 SCOPUS ID: 2-s2.0-0025185706 11/01/1990 6 Citations
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