Medical College of Wisconsin
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Zachary Smith DO

Zachary Smith DO profile photo picture

Associate Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Gastroenterology
Program: Administration


I am willing to mentor a junior faculty member.
I am willing to collaborate on research projects.


Leadership Positions

  • Associate Chief, Section of Gastroenterology, Clement J. Zablocki VAMC
  • Director, Advanced Endoscopy Fellowship Program
  • Associate Chief, Director of Clinical Research, Division of Gastroenterology and Hepatology
  • Publications (52)

  • Consensus-based development of a causal attribution system for post-ERCP adverse events. (Forbes N, Elmunzer BJ, Keswani RN, Hilsden RJ, Hall M, Anderson JT, Arvanitakis M, Chen YI, Duloy A, Elta GH, Maranki JL, Mergener K, Petersen BT, Sethi A, Siersema PD, Smith ZL, Telford JJ, Tse F, Cotton PB, Wani S) Gut 2022 Jul 11 PMID: 35817552 SCOPUS ID: 2-s2.0-85138182417 07/12/2022    
  • Evidence-Based Cognitive Endoscopy Simulators: Do They Exist? A Systematic Search and Evaluation of Existing Platforms. (Shah R, Kurin M, Satyavada S, Ismail M, Smith Z, Davitkov P, Isenberg G, Gottumukkala R, Faulx A, Falck-Ytter Y, Chak A) Dig Dis Sci 2022 Jun 15:1-6 PMID: 35704254 PMCID: PMC9199333 SCOPUS ID: 2-s2.0-85132298848 06/16/2022    
  • Incidence of sedation-related adverse events during ERCP with anesthesia assistance: a multicenter observational study. (Cummings LC, Liang C, Mascha EJ, Saager L, Smith ZL, Bhavani S, Vargo JJ, Cummings KC 3rd) Gastrointest Endosc 2022 Aug;96(2):269-281.e1 PMID: 35381231 SCOPUS ID: 2-s2.0-85132875287 04/06/2022       1 Citation
  • Response to Giri and Darak. (Satyavada S, Smith ZL) Am J Gastroenterol 2022 May 01;117(5):811 PMID: 35315811 SCOPUS ID: 2-s2.0-85129996999 03/23/2022    
  • Intracystic Glucose and Carcinoembryonic Antigen in Differentiating Histologically Confirmed Pancreatic Mucinous Neoplastic Cysts. (Smith ZL, Satyavada S, Simons-Linares R, Mok SRS, Martinez Moreno B, Aparicio JR, Chahal P) Am J Gastroenterol 2022 Mar 01;117(3):478-485 PMID: 35034045 SCOPUS ID: 2-s2.0-85125682555 01/17/2022       4 Citations
  • Meet EBE: The Development of an Evidence-Based Endoscopy Simulator. (Shah R, Satyavada S, Kurin M, Ismail M, Smith ZL, Davitkov P, Isenberg G, Raju GS, Faulx A, Falck-Ytter Y, Chak A) Clin Gastroenterol Hepatol 2022 May;20(5):e1180-e1187 PMID: 34896643 SCOPUS ID: 2-s2.0-85123711660 12/14/2021    
  • Factors Associated with the Development of Gastrointestinal Symptoms in Patients Hospitalized with Covid-19. (Aroniadis OC, Wang X, Gong T, Forbes N, Yang JY, Canakis A, Elmunzer BJ, Yadav D, North American Alliance for the Study of Digestive Manifestations of Covid-19) Dig Dis Sci 2022 Aug;67(8):3860-3871 PMID: 34751837 PMCID: PMC8575674 SCOPUS ID: 2-s2.0-85118765038 11/10/2021       1 Citation
  • Advanced Endoscopic Techniques for the Diagnosis of Pancreatic Cancer and Management of Biliary and GastricOutlet Obstruction (Nakai Y, Smith Z, Chang KJ, Dua KS) Surgical Oncology Clinics of North America October 2021;30(4):639-656 SCOPUS ID: 2-s2.0-85111001118 10/01/2021    
  • Advanced Endoscopic Techniques for the Diagnosis of Pancreatic Cancer and Management of Biliary and GastricOutlet Obstruction. (Nakai Y, Smith Z, Chang KJ, Dua KS) Surg Oncol Clin N Am 2021 Oct;30(4):639-656 PMID: 34511187 SCOPUS ID: 2-s2.0-85111001118 09/14/2021    
  • Behind the mask: physiologic effects of facial personal protective equipment during endoscopy (Chisholm PR, Smith ZL) Gastrointestinal Endoscopy July 2021;94(1):169-171 SCOPUS ID: 2-s2.0-85105456884 07/01/2021    
  • Behind the mask: physiologic effects of facial personal protective equipment during endoscopy. (Chisholm PR, Smith ZL) Gastrointest Endosc 2021 Jul;94(1):169-171 PMID: 33975713 PMCID: PMC8106483 SCOPUS ID: 2-s2.0-85105456884 05/13/2021    
  • The role of endoscopy and findings in COVID-19 patients, an early North American Cohort. (Kuftinec G, Elmunzer BJ, Amin S, North American Alliance for the Study of Digestive Manifestations of Covid-19) BMC Gastroenterol 2021 May 07;21(1):205 PMID: 33962582 PMCID: PMC8102844 SCOPUS ID: 2-s2.0-85105708182 05/09/2021    
  • Cold versus hot endoscopic mucosal resection for large sessile colon polyps: a cost-effectiveness analysis. (Mehta D, Loutfy AH, Kushnir VM, Faulx AL, Smith ZL) Endoscopy 2022 Apr;54(4):367-375 PMID: 33782926 SCOPUS ID: 2-s2.0-85107296278 03/31/2021       1 Citation
  • Development and validation of a patient-reported scale for tolerability of endoscopic procedures using conscious sedation. (Forbes N, Chau M, Koury HF, Lethebe BC, Smith ZL, Wani S, Keswani RN, Elmunzer BJ, Anderson JT, Heitman SJ, Hilsden RJ) Gastrointest Endosc 2021 Jul;94(1):103-110.e2 PMID: 33385464 PMCID: PMC8761529 SCOPUS ID: 2-s2.0-85103731041 01/02/2021       5 Citations
  • Risk of Venous Thromboembolism in Acute Necrotizing Pancreatitis: A Large Database Study (Ahmad DS, Mansoor E, Alikhan MM, Rana MN, Panhwar MS, Wong RCK, Smith ZL) Pancreas 2021; 50(1):71-76. 01/01/2021    
  • Risk of Venous Thromboembolism in Acute Necrotizing Pancreatitis: A Large Database Study (Ahmad DS, Mansoor E, Alikhan MM, Rana MN, Panhwar MS, Wong RCK, Smith ZL) Pancreas 2021;50(1):71-76 SCOPUS ID: 2-s2.0-85098148082 01/01/2021       1 Citation
  • Risk of Venous Thromboembolism in Acute Necrotizing Pancreatitis: A Large Database Study. (Ahmad DS, Mansoor E, Alikhan MM, Rana MN, Panhwar MS, Wong RCK, Smith ZL) Pancreas 2021 Jan 01;50(1):71-76 PMID: 33370025 SCOPUS ID: 2-s2.0-85098148082 12/29/2020       1 Citation
  • Percutaneous- and EUS-guided gastroenterostomy for malignant afferent limb syndrome. (Adoor D, Smith ZL) VideoGIE 2020 Nov;5(11):542-544 PMID: 33204911 PMCID: PMC7649849 SCOPUS ID: 2-s2.0-85087308666 11/19/2020       2 Citations
  • Association Between Preadmission Acid Suppressive Medication Exposure and Severity of Illness in Patients Hospitalized With COVID-19. (Elmunzer BJ, Wolf BJ, Scheiman JM, Tierney WM, Taylor JR, North American Alliance for the Study of Digestive Manifestations of COVID-19) Gastroenterology 2021 Mar;160(4):1417-1422.e14 PMID: 33189702 PMCID: PMC7659802 SCOPUS ID: 2-s2.0-85102113444 11/16/2020       8 Citations
  • The Next EPISOD: Trends in Utilization of Endoscopic Sphincterotomy for Sphincter of Oddi Dysfunction from 2010-2019. (Smith ZL, Shah R, Elmunzer BJ, Chak A) Clin Gastroenterol Hepatol 2022 Mar;20(3):e600-e609 PMID: 33161159 SCOPUS ID: 2-s2.0-85111943361 11/09/2020       2 Citations
  • Digestive Manifestations in Patients Hospitalized With Coronavirus Disease 2019. (Elmunzer BJ, Spitzer RL, Foster LD, Merchant AA, Howard EF, Patel VA, West MK, Qayed E, Nustas R, Zakaria A, Piper MS, Taylor JR, Jaza L, Forbes N, Chau M, Lara LF, Papachristou GI, Volk ML, Hilson LG, Zhou S, Kushnir VM, Lenyo AM, McLeod CG, Amin S, Kuftinec GN, Yadav D, Fox C, Kolb JM, Pawa S, Pawa R, Canakis A, Huang C, Jamil LH, Aneese AM, Glamour BK, Smith ZL, Hanley KA, Wood J, Patel HK, Shah JN, Agarunov E, Sethi A, Fogel EL, McNulty G, Haseeb A, Trieu JA, Dixon RE, Yang JY, Mendelsohn RB, Calo D, Aroniadis OC, LaComb JF, Scheiman JM, Sauer BG, Dang DT, Piraka CR, Shah ED, Pohl H, Tierney WM, Mitchell S, Condon A, Lenhart A, Dua KS, Kanagala VS, Kamal A, Singh VK, Pinto-Sanchez MI, Hutchinson JM, Kwon RS, Korsnes SJ, Singh H, Solati Z, Willingham FF, Yachimski PS, Conwell DL, Mosier E, Azab M, Patel A, Buxbaum J, Wani S, Chak A, Hosmer AE, Keswani RN, DiMaio CJ, Bronze MS, Muthusamy R, Canto MI, Gjeorgjievski VM, Imam Z, Odish F, Edhi AI, Orosey M, Tiwari A, Patwardhan S, Brown NG, Patel AA, Ordiah CO, Sloan IP, Cruz L, Koza CL, Okafor U, Hollander T, Furey N, Reykhart O, Zbib NH, Damianos JA, Esteban J, Hajidiacos N, Saul M, Mays M, Anderson G, Wood K, Mathews L, Diakova G, Caisse M, Wakefield L, Nitchie H, Waljee AK, Tang W, Zhang Y, Zhu J, Deshpande AR, Rockey DC, Alford TB, Durkalski V, North American Alliance for the Study of Digestive Manifestations of COVID-19) Clin Gastroenterol Hepatol 2021 Jul;19(7):1355-1365.e4 PMID: 33010411 PMCID: PMC7527302 SCOPUS ID: 2-s2.0-85101865891 10/04/2020       31 Citations
  • Pharmacotherapy for Obesity-Trends Using a Population Level National Database. (Elangovan A, Shah R, Smith ZL) Obes Surg 2021 Mar;31(3):1105-1112 PMID: 32986169 SCOPUS ID: 2-s2.0-85091683149 09/29/2020       11 Citations
  • Real-World Practice Patterns in the Era of Rectal Indomethacin for Prophylaxis Against Post-ERCP Pancreatitis in a High-Risk Cohort. (Smith ZL, Elmunzer BJ, Cooper GS, Chak A) Am J Gastroenterol 2020 Jun;115(6):934-940 PMID: 32496740 SCOPUS ID: 2-s2.0-85085963163 06/05/2020       8 Citations
  • An Unsuccessful Randomized Trial of Percutaneous vs Endoscopic Drainage of Suspected Malignant Hilar Obstruction. (Elmunzer BJ, Smith ZL, Tarnasky P, Wang AY, Yachimski P, Banovac F, Buscaglia JM, Buxbaum J, Chak A, Chong B, Coté GA, Draganov PV, Dua K, Durkalski V, Geller BS, Jamil LH, Keswani RN, Khashab MA, Law R, Lo SK, McCarthy S, Selby JB, Singh VK, Taylor JR, Willingham FF, Spitzer RL, Foster LD, INTERCPT study group and the United States Cooperative for Outcomes Research in Endoscopy (USCORE)) Clin Gastroenterol Hepatol 2021 Jun;19(6):1282-1284 PMID: 32454259 PMCID: PMC8776356 SCOPUS ID: 2-s2.0-85103976576 05/27/2020       7 Citations
  • Plans to Reactivate Gastroenterology Practices Following the COVID-19 Pandemic: A Survey of North American Centers. (Kushnir VM, Berzin TM, Elmunzer BJ, Mendelsohn RB, Patel V, Pawa S, Smith ZL, Keswani RN, North American Alliance for the Study of Digestive Manifestations of COVID-19) Clin Gastroenterol Hepatol 2020 Sep;18(10):2287-2294.e1 PMID: 32447019 PMCID: PMC7242181 SCOPUS ID: 2-s2.0-85089412387 05/25/2020       18 Citations
  • Changes in Gastroenterology and Endoscopy Practices in Response to the Coronavirus Disease 2019 Pandemic: Results From a North American Survey. (Forbes N, Smith ZL, Spitzer RL, Keswani RN, Wani SB, Elmunzer BJ, North American Alliance for the Study of Digestive Manifestations of COVID-19) Gastroenterology 2020 Aug;159(2):772-774.e13 PMID: 32376410 PMCID: PMC7196540 SCOPUS ID: 2-s2.0-85085892805 05/08/2020       56 Citations
  • What constitutes urgent endoscopy? A social media snapshot of gastroenterologists' views during the COVID-19 pandemic. (Bilal M, Simons M, Rahman AU, Smith ZL, Umar S, Cohen J, Sawhney MS, Berzin TM, Pleskow DK) Endosc Int Open 2020 May;8(5):E693-E698 PMID: 32355889 PMCID: PMC7165009 05/02/2020    
  • COVID-19 pandemic through the lens of a gastroenterology fellow: looking for the silver lining. (Shah R, Satyavada S, Ismail M, Kurin M, Smith ZL, Cooper GS, Chak A) Gastrointest Endosc 2020 Aug;92(2):394-398 PMID: 32247755 PMCID: PMC7130320 SCOPUS ID: 2-s2.0-85082962939 04/06/2020       20 Citations
  • Type of sedation and the need for unplanned interventions during ERCP: analysis of the clinical outcomes research initiative national endoscopic database (CORI-NED). (Smith ZL, Nickel KB, Olsen MA, Vargo JJ, Kushnir VM) Frontline Gastroenterol 2020 Mar;11(2):104-110 PMID: 32133108 PMCID: PMC7043086 SCOPUS ID: 2-s2.0-85065572931 03/07/2020       5 Citations
  • Outcomes of endoscopic treatment of leaks and fistulae after sleeve gastrectomy: results from a large multicenter U.S. cohort. (Smith ZL, Park KH, Llano EM, Donboli K, Fayad L, Han S, Kang L, Simril RT 2nd, Patel R, Hollander T, Rogers MC, Elmunzer BJ, Siddiqui UD, Aadam AA, Mullady DK, Lang GD, Das KK, Jamil LH, Lo SK, Gaddam S, Chapman CG, Keswani RN, Wani S, Cote GA, Kumbhari V, Kushnir VM) Surg Obes Relat Dis 2019 Jun;15(6):850-855 PMID: 31122826 SCOPUS ID: 2-s2.0-85065793580 05/28/2019       9 Citations
  • Anesthesia-administered sedation for endoscopic retrograde cholangiopancreatography: monitored anesthesia care or general endotracheal anesthesia? (Smith ZL, Das KK, Kushnir VM) Curr Opin Anaesthesiol 2019 Aug;32(4):531-537 PMID: 30994476 SCOPUS ID: 2-s2.0-85069235441 04/18/2019       7 Citations
  • Longitudinal relationship between social media activity and article citations in the journal Gastrointestinal Endoscopy. (Smith ZL, Chiang AL, Bowman D, Wallace MB) Gastrointest Endosc 2019 Jul;90(1):77-83 PMID: 30935934 SCOPUS ID: 2-s2.0-85067307524 04/03/2019       36 Citations
  • Patient selection in studies evaluating esophageal stents during neoadjuvant therapy. (Smith ZL, Dua KS) Gastrointest Endosc 2019 Jan;89(1):205-206 PMID: 30567679 SCOPUS ID: 2-s2.0-85058217485 12/21/2018       2 Citations
  • A randomized controlled trial evaluating general endotracheal anesthesia versus monitored anesthesia care and the incidence of sedation-related adverse events during ERCP in high-risk patients. (Smith ZL, Mullady DK, Lang GD, Das KK, Hovis RM, Patel RS, Hollander TG, Elsner J, Ifune C, Kushnir VM) Gastrointest Endosc 2019 Apr;89(4):855-862 PMID: 30217726 SCOPUS ID: 2-s2.0-85058233248 09/16/2018       34 Citations
  • Health-related quality of life and long-term outcomes after endoscopic therapy for walled-off pancreatic necrosis. (Smith ZL, Gregory MH, Elsner J, Alajlan BA, Kodali D, Hollander T, Sayuk GS, Lang GD, Das KK, Mullady DK, Early DS, Kushnir VM) Dig Endosc 2019 Jan;31(1):77-85 PMID: 30152143 SCOPUS ID: 2-s2.0-85054182285 08/29/2018       4 Citations
  • Radiofrequency ablation devices. (ASGE Technology Committee, Navaneethan U, Thosani N, Goodman A, Manfredi M, Pannala R, Parsi MA, Smith ZL, Sullivan SA, Banerjee S, Maple JT) VideoGIE 2017 Oct;2(10):252-259 PMID: 29905337 PMCID: PMC5992954 SCOPUS ID: 2-s2.0-85044862336 06/16/2018       24 Citations
  • The importance of early recognition in management of ERCP-related perforations. (Bill JG, Smith Z, Brancheck J, Elsner J, Hobbs P, Lang GD, Early DS, Das K, Hollander T, Doyle MBM, Fields RC, Hawkins WG, Strasberg SM, Hammill C, Chapman WC, Edmundowicz S, Mullady DK, Kushnir VM) Surg Endosc 2018 Dec;32(12):4841-4849 PMID: 29770887 SCOPUS ID: 2-s2.0-85047160519 05/18/2018       9 Citations
  • Prolonged Cecal Insertion Time Is Not Associated with Decreased Adenoma Detection When a Longer Withdrawal Time Is Achieved. (Fritz CDL, Smith ZL, Elsner J, Hollander T, Early D, Kushnir V) Dig Dis Sci 2018 Nov;63(11):3120-3125 PMID: 29721773 SCOPUS ID: 2-s2.0-85054647464 05/04/2018       6 Citations
  • Safety and efficacy of lumen-apposing metal stents with and without simultaneous double-pigtail plastic stents for draining pancreatic pseudocyst. (Aburajab M, Smith Z, Khan A, Dua K) Gastrointest Endosc 2018 May;87(5):1248-1255 PMID: 29233670 SCOPUS ID: 2-s2.0-85043785665 12/14/2017       31 Citations
  • Endoscopic anti-reflux devices (with videos). (ASGE Technology Committee, Thosani N, Goodman A, Manfredi M, Navaneethan U, Parsi MA, Smith ZL, Sullivan SA, Banerjee S, Maple JT) Gastrointest Endosc 2017 Dec;86(6):931-948 PMID: 29054276 SCOPUS ID: 2-s2.0-85031734553 10/22/2017       13 Citations
  • A Novel Protocol Obviates Endoscope Sampling for Carbapenem-Resistant Enterobacteriaceae: Experience of a Center with a Prior Outbreak. (Smith ZL, Dua A, Saeian K, Ledeboer NA, Graham MB, Aburajab M, Ballard DD, Khan AH, Dua KS) Dig Dis Sci 2017 Nov;62(11):3100-3109 PMID: 28681083 SCOPUS ID: 2-s2.0-85021843628 07/07/2017       10 Citations
  • Self-Expanding Metal Stents Improve Swallowing and Maintain Nutrition During Neoadjuvant Therapy for Esophageal Cancer. (Smith ZL, Gonzaga JE, Haasler GB, Gore EM, Dua KS) Dig Dis Sci 2017 Jun;62(6):1647-1656 PMID: 28391413 SCOPUS ID: 2-s2.0-85017140892 04/10/2017       6 Citations
  • Devices for use with EUS. (ASGE Technology Committee, Hwang JH, Aslanian HR, Thosani N, Goodman A, Manfredi M, Navaneethan U, Pannala R, Parsi MA, Smith ZL, Sullivan SA, Banerjee S, Maple JT) VideoGIE 2017 Mar;2(3):35-45 PMID: 29905238 PMCID: PMC5990542 SCOPUS ID: 2-s2.0-85018471452 02/12/2017       9 Citations
  • Interventional EUS (with videos). (ASGE Technology Committee, Maple JT, Pannala R, Abu Dayyeh BK, Aslanian HR, Enestvedt BK, Goodman A, Komanduri S, Manfredi M, Navaneethan U, Parsi MA, Smith ZL, Thosani N, Sullivan SA, Banerjee S) Gastrointest Endosc 2017 Mar;85(3):465-481 PMID: 28117034 SCOPUS ID: 2-s2.0-85009821192 01/25/2017       16 Citations
  • Automated endoscope reprocessors. (ASGE Technology Committee, Parsi MA, Sullivan SA, Goodman A, Manfredi M, Navaneethan U, Pannala R, Smith ZL, Thosani N, Banerjee S, Maple JT) Gastrointest Endosc 2016 Dec;84(6):885-892 PMID: 27765382 SCOPUS ID: 2-s2.0-85005877158 10/22/2016       10 Citations
  • Invasive intraductal papillary carcinoma of the bile duct masquerading as a common hepatic duct stone. (Smith ZL, Daniel KE, Pant M, Dua KS, Aburajab M) VideoGIE 2016 Dec;1(4):68-69 PMID: 29905233 PMCID: PMC5990414 SCOPUS ID: 2-s2.0-85018483950 09/25/2016    
  • Cholangiopancreatoscopy. (ASGE Technology Committee, Komanduri S, Thosani N, Abu Dayyeh BK, Aslanian HR, Enestvedt BK, Manfredi M, Maple JT, Navaneethan U, Pannala R, Parsi MA, Smith ZL, Sullivan SA, Banerjee S) Gastrointest Endosc 2016 Aug;84(2):209-21 PMID: 27236413 SCOPUS ID: 2-s2.0-84970028900 05/30/2016       52 Citations
  • Per-oral endoscopic myotomy (with video). (ASGE Technology Committee, Pannala R, Abu Dayyeh BK, Aslanian HR, Enestvedt BK, Komanduri S, Manfredi M, Maple JT, Navaneethan U, Parsi MA, Smith ZL, Sullivan SA, Thosani N, Banerjee S) Gastrointest Endosc 2016 Jun;83(6):1051-60 PMID: 27033144 SCOPUS ID: 2-s2.0-84962303047 04/02/2016       17 Citations
  • ASGE Technology Committee systematic review and meta-analysis assessing the ASGE Preservation and Incorporation of Valuable Endoscopic Innovations thresholds for adopting real-time imaging-assisted endoscopic targeted biopsy during endoscopic surveillance of Barrett's esophagus. (ASGE Technology Committee, Thosani N, Abu Dayyeh BK, Sharma P, Aslanian HR, Enestvedt BK, Komanduri S, Manfredi M, Navaneethan U, Maple JT, Pannala R, Parsi MA, Smith ZL, Sullivan SA, Banerjee S) Gastrointest Endosc 2016 Apr;83(4):684-98.e7 PMID: 26874597 SCOPUS ID: 2-s2.0-84960338703 02/15/2016       121 Citations
  • Transmission of carbapenem-resistant Enterobacteriaceae during ERCP: time to revisit the current reprocessing guidelines. (Smith ZL, Oh YS, Saeian K, Edmiston CE Jr, Khan AH, Massey BT, Dua KS) Gastrointest Endosc 2015 Apr;81(4):1041-5 PMID: 25638508 SCOPUS ID: 2-s2.0-84925348324 02/02/2015       72 Citations
  • Relationship between mesenteric abnormalities on computed tomography and malignancy: clinical findings and outcomes of 359 patients. (Smith ZL, Sifuentes H, Deepak P, Ecanow DB, Ehrenpreis ED) J Clin Gastroenterol 2013;47(5):409-14 PMID: 23188076 SCOPUS ID: 2-s2.0-84876408369 11/29/2012       19 Citations
  • Suboptimal reporting of adverse medical events to the FDA Adverse Events Reporting System by nurse practitioners and physician assistants. (Ehrenpreis ED, Sifuentes H, Ehrenpreis JE, Smith ZL, Marshall ML) Expert Opin Drug Saf 2012 Mar;11(2):177-83 PMID: 22316142 SCOPUS ID: 2-s2.0-84857387094 02/10/2012       7 Citations
  • Last update: 12/05/2022