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All Publications for Christopher R. Chitambar MD (111)

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• Association of Circulating Tumor DNA and Circulating Tumor Cells After Neoadjuvant Chemotherapy With Disease Recurrence in Patients With Triple-Negative Breast Cancer: Preplanned Secondary Analysis of the BRE12-158 Randomized Clinical Trial. (Radovich M, Jiang G, Hancock BA, Chitambar C, Nanda R, Falkson C, Lynce FC, Gallagher C, Isaacs C, Blaya M, Paplomata E, Walling R, Daily K, Mahtani R, Thompson MA, Graham R, Cooper ME, Pavlick DC, Albacker LA, Gregg J, Solzak JP, Chen YH, Bales CL, Cantor E, Shen F, Storniolo AMV, Badve S, Ballinger TJ, Chang CL, Zhong Y, Savran C, Miller KD, Schneider BP) JAMA Oncol 2020 Sep 01;6(9):1410-1415 PMID: 32644110 PMCID: PMC7349081 Scopus ID: 2-s2.0-85088116098 07/10/2020
• The cytotoxicity of gallium maltolate in glioblastoma cells is enhanced by metformin through combined action on mitochondrial complex 1. (Alhajala HS, Markley JL, Kim JH, Al-Gizawiy MM, Schmainda KM, Kuo JS, Chitambar CR) Oncotarget 2020 Apr 28;11(17):1531-1544 PMID: 32391122 PMCID: PMC7197450 Scopus ID: 2-s2.0-85086103488 05/12/2020
• Dendrimer–didox nanocomplex for enhanced anticancer activity (Kaul M, Alhajala H, Chitambar CR, Chauhan A) Journal of Nanoparticle Research 1 April 2020;22(4) Scopus ID: 2-s2.0-85083500020 04/01/2020
• A high mitotic score in breast cancer after neoadjuvant chemotherapy is predictive of outcome and associated with a distinct morphology. (Arispe Angulo KR, Jawa Z, Visotcky A, Majidi SS, Chitambar CR, Jorns JM) Histopathology 2020 Apr;76(5):661-670 PMID: 31849088 Scopus ID: 2-s2.0-85081892704 12/19/2019
• High-dose intravenous methotrexate in the management of breast cancer with leptomeningeal disease: Case series and review of the literature. (Kapke JT, Schneidewend RJ, Jawa ZA, Huang CC, Connelly JM, Chitambar CR) Hematol Oncol Stem Cell Ther 2019 Dec;12(4):189-193 PMID: 31629723 Scopus ID: 2-s2.0-85075443191 10/21/2019
• Synergistic inhibition of tumor cell proliferation by metformin and mito-metformin in the presence of iron chelators. (Cheng G, Zielonka J, Hardy M, Ouari O, Chitambar CR, Dwinell MB, Kalyanaraman B) Oncotarget 2019 May 28;10(37):3518-3532 PMID: 31191823 PMCID: PMC6544408 Scopus ID: 2-s2.0-85089087803 06/14/2019
• Irradiation of pediatric glioblastoma cells promotes radioresistance and enhances glioma malignancy via genome-wide transcriptome changes. (Alhajala HS, Nguyen HS, Shabani S, Best B, Kaushal M, Al-Gizawiy MM, Erin Ahn EY, Knipstein JA, Mirza S, Schmainda KM, Chitambar CR, Doan NB) Oncotarget 2018 Sep 25;9(75):34122-34131 PMID: 30344926 PMCID: PMC6183347 Scopus ID: 2-s2.0-85053940800 10/23/2018
• Methotrexate-induced Leukoencephalopathy without Typical Restricted Diffusion on Diffusion-weighted Imaging and the Utility of Magnetic Resonance Spectroscopy to Support the Diagnosis. (Doan N, Patel M, Nguyen HS, Doan H, Shabani S, Gelsomino M, Mountoure A, Janich K, Chitambar CR) Asian J Neurosurg 2018;13(3):848-850 PMID: 30283563 PMCID: PMC6159078 10/05/2018
• Irradiation of pediatric glioblastoma cells promotes radioresistance and enhances glioma malignancy via genome-wide transcriptome changes (Alhajala HS, Nguyen HS, Shabani S, Best B, Kaushal M, Al-Gizawiy MM, Ahn EYE, Knipstein JA, Mirza S, Schmainda KM, Chitambar CR, Doan NB) Oncotarget 1 September 2018;9(75):34122-34131 Scopus ID: 2-s2.0-85053940800 09/01/2018
• Does Progesterone Receptor Matter in the Risk of Recurrence for Patients With Ductal Carcinoma in Situ? (Chaudhary LN, Jawa Z, Hanif A, Szabo A, Kamaraju S, Cheng YC, Chitambar CR) WMJ 2018 Jun;117(2):62-67 PMID: 30048574 Scopus ID: 2-s2.0-85051516380 07/27/2018
• Identification of radiation responsive genes and transcriptome profiling via complete RNA sequencing in a stable radioresistant U87 glioblastoma model. (Doan NB, Nguyen HS, Alhajala HS, Jaber B, Al-Gizawiy MM, Ahn EE, Mueller WM, Chitambar CR, Mirza SP, Schmainda KM) Oncotarget 2018 May 04;9(34):23532-23542 PMID: 29805753 PMCID: PMC5955095 Scopus ID: 2-s2.0-85046774803 05/29/2018
• Gallium Maltolate Disrupts Tumor Iron Metabolism and Retards the Growth of Glioblastoma by Inhibiting Mitochondrial Function and Ribonucleotide Reductase. (Chitambar CR, Al-Gizawiy MM, Alhajala HS, Pechman KR, Wereley JP, Wujek R, Clark PA, Kuo JS, Antholine WE, Schmainda KM) Mol Cancer Ther 2018 Jun;17(6):1240-1250 PMID: 29592883 PMCID: PMC5984712 Scopus ID: 2-s2.0-85048073666 03/30/2018
• Metalloglycomics. (Farrell NP, Gorle AK, Peterson EJ, Berners-Price SJ) Met Ions Life Sci 2018 Feb 05;18 PMID: 29394023 Scopus ID: 2-s2.0-85045540738 02/03/2018
• Gallium Complexes as Anticancer Drugs. (Chitambar CR) Met Ions Life Sci 2018 Feb 05;18 PMID: 29394029 Scopus ID: 2-s2.0-85049265078 02/03/2018
• Acid ceramidase and its inhibitors: a de novo drug target and a new class of drugs for killing glioblastoma cancer stem cells with high efficiency. (Doan NB, Alhajala H, Al-Gizawiy MM, Mueller WM, Rand SD, Connelly JM, Cochran EJ, Chitambar CR, Clark P, Kuo J, Schmainda KM, Mirza SP) Oncotarget 2017 Dec 22;8(68):112662-112674 PMID: 29348854 PMCID: PMC5762539 Scopus ID: 2-s2.0-85038823142 01/20/2018
• Acid ceramidase confers radioresistance to glioblastoma cells. (Doan NB, Nguyen HS, Al-Gizawiy MM, Mueller WM, Sabbadini RA, Rand SD, Connelly JM, Chitambar CR, Schmainda KM, Mirza SP) Oncol Rep 2017 Oct;38(4):1932-1940 PMID: 28765947 PMCID: PMC5652937 Scopus ID: 2-s2.0-85029804998 08/03/2017
• Acid ceramidase is a novel drug target for pediatric brain tumors. (Doan NB, Nguyen HS, Montoure A, Al-Gizawiy MM, Mueller WM, Kurpad S, Rand SD, Connelly JM, Chitambar CR, Schmainda KM, Mirza SP) Oncotarget 2017 Apr 11;8(15):24753-24761 PMID: 28445970 PMCID: PMC5421885 Scopus ID: 2-s2.0-85017541087 04/28/2017
• The therapeutic potential of iron-targeting gallium compounds in human disease: From basic research to clinical application. (Chitambar CR) Pharmacol Res 2017 Jan;115:56-64 PMID: 27856328 Scopus ID: 2-s2.0-84995688314 11/20/2016
• Gallium and its competing roles with iron in biological systems. (Chitambar CR) Biochim Biophys Acta 2016 Aug;1863(8):2044-53 PMID: 27150508 Scopus ID: 2-s2.0-84971367758 05/08/2016
• Impact of obesity and exercise on chemotherapy-related fatigue. (Herath K, Peswani N, Chitambar CR) Support Care Cancer 2016 Oct;24(10):4257-62 PMID: 27146493 Scopus ID: 2-s2.0-84966373255 05/06/2016
• Relevance of progesterone receptor immunohistochemical staining to Oncotype DX recurrence score. (Chaudhary LN, Jawa Z, Szabo A, Visotcky A, Chitambar CR) Hematol Oncol Stem Cell Ther 2016 Jun;9(2):48-54 PMID: 26808222 Scopus ID: 2-s2.0-84955577378 01/26/2016
• p38γ MAPK Is a Therapeutic Target for Triple-Negative Breast Cancer by Stimulation of Cancer Stem-Like Cell Expansion. (Qi X, Yin N, Ma S, Lepp A, Tang J, Jing W, Johnson B, Dwinell MB, Chitambar CR, Chen G) Stem Cells 2015 Sep;33(9):2738-47 PMID: 26077647 PMCID: PMC4792188 Scopus ID: 2-s2.0-84940467357 06/17/2015
• Gallium maltolate inhibits human cutaneous T-cell lymphoma tumor development in mice. (Wu X, Wang TW, Lessmann GM, Saleh J, Liu X, Chitambar CR, Hwang ST) J Invest Dermatol 2015 Mar;135(3):877-884 PMID: 25371972 Scopus ID: 2-s2.0-84922673479 11/06/2014
• Hematologic aspects of iron deficiency and less common nutritional anemias (Chitambar CR, Antony AC) Modern Nutrition in Health and Disease: Eleventh Edition 22 December 2012:1372-1384 Scopus ID: 2-s2.0-84971207705 12/22/2012
• Iron-targeting antitumor activity of gallium compounds and novel insights into triapine(®)-metal complexes. (Chitambar CR, Antholine WE) Antioxid Redox Signal 2013 Mar 10;18(8):956-72 PMID: 22900955 PMCID: PMC3557436 Scopus ID: 2-s2.0-84873871117 08/21/2012
• Gallium-containing anticancer compounds. (Chitambar CR) Future Med Chem 2012 Jun;4(10):1257-72 PMID: 22800370 PMCID: PMC3574811 Scopus ID: 2-s2.0-84863903473 07/18/2012
• A Phase II Study of Concurrent Docetaxel, Epirubicin and Cyclophosphamide as a Neoadjuvant Chemotherapy Regimen in Patients with Locally Advanced Breast Cancer. (Yao X, Hosenpud J, Chitambar CR, Charlson J, Cheng YC) J Cancer 2012;3:145-51 PMID: 22481980 PMCID: PMC3319980 04/07/2012
• p38γ mitogen-activated protein kinase (MAPK) confers breast cancer hormone sensitivity by switching estrogen receptor (ER) signaling from classical to nonclassical pathway via stimulating ER phosphorylation and c-Jun transcription. (Qi X, Zhi H, Lepp A, Wang P, Huang J, Basir Z, Chitambar CR, Myers CR, Chen G) J Biol Chem 2012 Apr 27;287(18):14681-91 PMID: 22399296 PMCID: PMC3340246 Scopus ID: 2-s2.0-84860370781 03/09/2012
• Cytotoxic Evaluation of 3-Aminopyridine-2-Carboxaldehyde Thiosemicarbazone, 3-AP, in Peripheral Blood Lymphocytes of Patients with Refractory Solid Tumors using Electron Paramagnetic Resonance. (Kolesar JM, Sachidanandam K, Schelman WR, Eickhoff J, Holen KD, Traynor AM, Alberti DB, Thomas JP, Chitambar CR, Wilding G, Antholine WE) Exp Ther Med 2011 Jan;2(1):119-123 PMID: 21373381 PMCID: PMC3046871 03/05/2011
• Medical applications and toxicities of gallium compounds. (Chitambar CR) Int J Environ Res Public Health 2010 May;7(5):2337-61 PMID: 20623028 PMCID: PMC2898053 Scopus ID: 2-s2.0-77954789725 07/14/2010
• Intravascular large B-cell lymphoma, an exclusively small vessel disease? A case report and review of literature. (Yao X, Saad A, Chitambar CR) Leuk Res 2010 Oct;34(10):e275-7 PMID: 20542564 Scopus ID: 2-s2.0-77955983811 06/15/2010
• A novel gallium compound synergistically enhances bortezomib-induced apoptosis in mantle cell lymphoma cells. (Chitambar CR, Purpi DP) Leuk Res 2010 Jul;34(7):950-3 PMID: 20334913 PMCID: PMC2875307 Scopus ID: 2-s2.0-77952958393 03/26/2010
• Role of oxidative stress in the induction of metallothionein-2A and heme oxygenase-1 gene expression by the antineoplastic agent gallium nitrate in human lymphoma cells. (Yang M, Chitambar CR) Free Radic Biol Med 2008 Sep 15;45(6):763-72 PMID: 18586083 PMCID: PMC2610863 Scopus ID: 2-s2.0-55249114464 07/01/2008
• Electron paramagnetic resonance study of peripheral blood mononuclear cells from patients with refractory solid tumors treated with Triapine. (Kolesar JM, Schelman WR, Geiger PG, Holen KD, Traynor AM, Alberti DB, Thomas JP, Chitambar CR, Wilding G, Antholine WE) J Inorg Biochem 2008 Apr;102(4):693-8 PMID: 18061679 PMCID: PMC2390869 Scopus ID: 2-s2.0-40649118985 12/07/2007
• Case reports: efalizumab-associated lymphoproliferative disease. (Bommakanti S, Patil A, Eshoa C, Chitambar CR) J Drugs Dermatol 2007 Jun;6(6):646-8 PMID: 17668531 Scopus ID: 2-s2.0-34548462490 08/03/2007
• Development of gallium compounds for treatment of lymphoma: gallium maltolate, a novel hydroxypyrone gallium compound, induces apoptosis and circumvents lymphoma cell resistance to gallium nitrate. (Chitambar CR, Purpi DP, Woodliff J, Yang M, Wereley JP) J Pharmacol Exp Ther 2007 Sep;322(3):1228-36 PMID: 17600139 Scopus ID: 2-s2.0-34548075249 06/30/2007
• Gene expression analysis of gallium-resistant and gallium-sensitive lymphoma cells reveals a role for metal-responsive transcription factor-1, metallothionein-2A, and zinc transporter-1 in modulating the antineoplastic activity of gallium nitrate. (Yang M, Kroft SH, Chitambar CR) Mol Cancer Ther 2007 Feb;6(2):633-43 PMID: 17308060 Scopus ID: 2-s2.0-33847409311 02/20/2007
• Gallium-induced cell death in lymphoma: role of transferrin receptor cycling, involvement of Bax and the mitochondria, and effects of proteasome inhibition. (Chitambar CR, Wereley JP, Matsuyama S) Mol Cancer Ther 2006 Nov;5(11):2834-43 PMID: 17121930 Scopus ID: 2-s2.0-33845208145 11/24/2006
• Expression of the hemochromatosis gene modulates the cytotoxicity of doxorubicin in breast cancer cells. (Chitambar CR, Kotamraju S, Wereley JP) Int J Cancer 2006 Nov 01;119(9):2200-4 PMID: 16823846 Scopus ID: 2-s2.0-33748875824 07/11/2006
• Resistance to the antineoplastic agent gallium nitrate results in marked alterations in intracellular iron and gallium trafficking: identification of novel intermediates. (Davies NP, Suryo Rahmanto Y, Chitambar CR, Richardson DR) J Pharmacol Exp Ther 2006 Apr;317(1):153-62 PMID: 16373528 Scopus ID: 2-s2.0-33645116062 12/24/2005
• Cellular iron metabolism: mitochondria in the spotlight. (Chitambar CR) Blood 2005 Mar 01;105(5):1844-5 PMID: 15747401 Scopus ID: 2-s2.0-14944381870 03/05/2005
• Apoptotic mechanisms of gallium nitrate: basic and clinical investigations. (Chitambar CR) Oncology (Williston Park) 2004 Nov;18(13 Suppl 10):39-44 PMID: 15651176 Scopus ID: 2-s2.0-14144250578 01/18/2005
• Gallium compounds as antineoplastic agents. (Chitambar CR) Curr Opin Oncol 2004 Nov;16(6):547-52 PMID: 15627016 Scopus ID: 2-s2.0-8344260657 01/01/2005
• Gallium nitrate for the treatment of non-Hodgkin's lymphoma. (Chitambar CR) Expert Opin Investig Drugs 2004 May;13(5):531-41 PMID: 15155128 Scopus ID: 2-s2.0-2642519499 05/25/2004
• Mantle cell lymphoma in lymph nodes with metastatic small cell carcinoma of lung: a diagnostic and treatment dilemma. (Kampalath B, Abed N, Chitambar CR, Vantuinen P, Chakrabarty G, Hanson G, Rao RN, Shidham VB, Chang CC) Leuk Lymphoma 2004 Feb;45(2):409-14 PMID: 15101734 Scopus ID: 2-s2.0-0842301452 04/23/2004
• Oxidant-induced iron signaling in Doxorubicin-mediated apoptosis. (Kotamraju S, Kalivendi SV, Konorev E, Chitambar CR, Joseph J, Kalyanaraman B) Methods Enzymol 2004;378:362-82 PMID: 15038980 Scopus ID: 2-s2.0-3042828610 03/25/2004
• Nitric oxide mitigates peroxide-induced iron-signaling, oxidative damage, and apoptosis in endothelial cells: role of proteasomal function? (Kotamraju S, Tampo Y, Kalivendi SV, Joseph J, Chitambar CR, Kalyanaraman B) Arch Biochem Biophys 2004 Mar 01;423(1):74-80 PMID: 14989268 Scopus ID: 2-s2.0-1042302131 03/03/2004
• Activity of gallium nitrate in patients with refractory lymphoma (Reddy GK, Chitambar CR, Jain VK) Clinical Lymphoma June 2004;5(1):17-18 Scopus ID: 2-s2.0-4344582208 01/01/2004
• A unique collision tumor in breast: invasive ductal carcinoma and mucosa-associated lymphoid tissue lymphoma. (Susnik B, Jordi Rowe J, Redlich PN, Chitambar C, Chang CC, Kampalath B) Arch Pathol Lab Med 2004 Jan;128(1):99-101 PMID: 14692838 Scopus ID: 2-s2.0-0346368240 12/25/2003
• Nitric oxide inhibits H2O2-induced transferrin receptor-dependent apoptosis in endothelial cells: Role of ubiquitin-proteasome pathway. (Kotamraju S, Tampo Y, Keszler A, Chitambar CR, Joseph J, Haas AL, Kalyanaraman B) Proc Natl Acad Sci U S A 2003 Sep 16;100(19):10653-8 PMID: 12958216 PMCID: PMC196859 09/06/2003
• Analysis of single nucleotide polymorphism C3435T of the multidrug resistance gene MDR1 in acute lymphoblastic leukemia. (Efferth T, Sauerbrey A, Steinbach D, Gebhart E, Drexler HG, Miyachi H, Chitambar CR, Becker CM, Zintl F, Humeny A) Int J Oncol 2003 Aug;23(2):509-17 PMID: 12851703 Scopus ID: 2-s2.0-0345974461 07/10/2003
• Expression of the hemochromatosis (HFE) gene modulates the cellular uptake of 67Ga. (Chitambar CR, Wereley JP) J Nucl Med 2003 Jun;44(6):943-6 PMID: 12791823 Scopus ID: 2-s2.0-0038500747 06/07/2003
• Gallium nitrate revisited. (Chitambar CR) Semin Oncol 2003 Apr;30(2 Suppl 5):1-4 PMID: 12776253 Scopus ID: 2-s2.0-0038824169 05/31/2003
• Oxidative stress-induced iron signaling is responsible for peroxide-dependent oxidation of dichlorodihydrofluorescein in endothelial cells: role of transferrin receptor-dependent iron uptake in apoptosis. (Tampo Y, Kotamraju S, Chitambar CR, Kalivendi SV, Keszler A, Joseph J, Kalyanaraman B) Circ Res 2003 Jan 10;92(1):56-63 PMID: 12522121 Scopus ID: 2-s2.0-0037428060 01/11/2003
• Genomic imbalances in drug-resistant T-cell acute lymphoblastic CEM leukemia cell lines. (Efferth T, Verdorfer I, Miyachi H, Sauerbrey A, Drexler HG, Chitambar CR, Haber M, Gebhart E) Blood Cells Mol Dis 2002;29(1):1-13 PMID: 12482398 Scopus ID: 2-s2.0-0344426671 12/17/2002
• Expression of MUM1/IRF4 correlates with clinical outcome in patients with B-cell chronic lymphocytic leukemia. (Chang CC, Lorek J, Sabath DE, Li Y, Chitambar CR, Logan B, Kampalath B, Cleveland RP) Blood 2002 Dec 15;100(13):4671-5 PMID: 12393648 Scopus ID: 2-s2.0-0037114759 10/24/2002
• CD5+ T-cell/histiocyte-rich large B-cell lymphoma. (Chang CC, Bunyi-Teopengco E, Eshoa C, Chitambar CR, Kampalath B) Mod Pathol 2002 Oct;15(10):1051-7 PMID: 12379751 Scopus ID: 2-s2.0-0036791569 10/16/2002
• Diagnosis, workup, and prognosis of cutaneous metastases of unknown primary origin. (Carroll MC, Fleming M, Chitambar CR, Neuburg M) Dermatol Surg 2002 Jun;28(6):533-5 PMID: 12081687 Scopus ID: 2-s2.0-0036288306 06/26/2002
• Transferrin receptor-dependent iron uptake is responsible for doxorubicin-mediated apoptosis in endothelial cells: role of oxidant-induced iron signaling in apoptosis. (Kotamraju S, Chitambar CR, Kalivendi SV, Joseph J, Kalyanaraman B) J Biol Chem 2002 May 10;277(19):17179-87 PMID: 11856741 Scopus ID: 2-s2.0-0037053406 02/22/2002
• Inhibition of malignant cell growth by 311, a novel iron chelator of the pyridoxal isonicotinoyl hydrazone class: effect on the R2 subunit of ribonucleotide reductase. (Green DA, Antholine WE, Wong SJ, Richardson DR, Chitambar CR) Clin Cancer Res 2001 Nov;7(11):3574-9 PMID: 11705879 Scopus ID: 2-s2.0-0035181433 11/14/2001
• Iron transport in a lymphoid cell line with the hemochromatosis C282Y mutation. (Chitambar CR, Wereley JP) Blood 2001 May 01;97(9):2734-40 PMID: 11313265 Scopus ID: 2-s2.0-0035353170 04/21/2001
• The anti-malarial artesunate is also active against cancer. (Efferth T, Dunstan H, Sauerbrey A, Miyachi H, Chitambar CR) Int J Oncol 2001 Apr;18(4):767-73 PMID: 11251172 Scopus ID: 2-s2.0-0035315838 03/17/2001
• Cellular adaptation to down-regulated iron transport into lymphoid leukaemic cells: effects on the expression of the gene for ribonucleotide reductase. (Chitambar CR, Wereley JP, Heiman T, Antholine WE, O'brien WJ) Biochem J 2000 Feb 01;345 Pt 3(Pt 3):681-5 PMID: 10642528 PMCID: PMC1220804 Scopus ID: 2-s2.0-0034142045 01/22/2000
• Increased sensitivity of hydroxyurea-resistant leukemic cells to gemcitabine. (Wong SJ, Myette MS, Wereley JP, Chitambar CR) Clin Cancer Res 1999 Feb;5(2):439-43 PMID: 10037195 Scopus ID: 2-s2.0-0032972705 02/26/1999
• Interaction of gallium nitrate with other inhibitors of ribonucleotide reductase: effects on the proliferation of human leukemic cells. (Myette MS, Elford HL, Chitambar CR) Cancer Lett 1998 Jul 17;129(2):199-204 PMID: 9719462 Scopus ID: 2-s2.0-0032546873 08/27/1998
• Gallium-pyridoxal isonicotinoyl hydrazone (Ga-PIH), a novel cytotoxic gallium complex. A comparative study with gallium nitrate. (Knorr GM, Chitambar CR) Anticancer Res 1998;18(3A):1733-7 PMID: 9673397 Scopus ID: 2-s2.0-0031594953 07/23/1998
• Transferrin receptor-dependent and -independent iron transport in gallium-resistant human lymphoid leukemic cells. (Chitambar CR, Wereley JP) Blood 1998 Jun 15;91(12):4686-93 PMID: 9616166 Scopus ID: 2-s2.0-0031811699 06/17/1998
• Resistance to the antitumor agent gallium nitrate in human leukemic cells is associated with decreased gallium/iron uptake, increased activity of iron regulatory protein-1, and decreased ferritin production. (Chitambar CR, Wereley JP) J Biol Chem 1997 May 02;272(18):12151-7 PMID: 9115286 Scopus ID: 2-s2.0-0030999608 05/02/1997
• Evaluation of continuous-infusion gallium nitrate and hydroxyurea in combination for the treatment of refractory non-Hodgkin's lymphoma. (Chitambar CR, Zahir SA, Ritch PS, Anderson T) Am J Clin Oncol 1997 Apr;20(2):173-8 PMID: 9124195 Scopus ID: 2-s2.0-0030947983 04/01/1997
• Effect of gallium nitrate therapy on Ga-67 scintigraphic detection of lymphoma: case report. (Akansel G, Liu Y, Chitambar CR, Kitapci MT, Akansel S, Krasnow AZ, Isitman AT, Collier BD) Clin Nucl Med 1997 Jan;22(1):21-4 PMID: 8993868 Scopus ID: 2-s2.0-0031031526 01/01/1997
• Modulation of in vitro and in vivo T-cell responses by transferrin-gallium and gallium nitrate. (Drobyski WR, Ul-Haq R, Majewski D, Chitambar CR) Blood 1996 Oct 15;88(8):3056-64 PMID: 8874204 Scopus ID: 2-s2.0-0029859282 10/15/1996
• Evaluation of transferrin and gallium-pyridoxal isonicotinoyl hydrazone as potential therapeutic agents to overcome lymphoid leukemic cell resistance to gallium nitrate. (Chitambar CR, Boon P, Wereley JP) Clin Cancer Res 1996 Jun;2(6):1009-15 PMID: 9816262 Scopus ID: 2-s2.0-0029950210 06/01/1996
• Effect of hydroxyurea on cellular iron metabolism in human leukemic CCRF-CEM cells: changes in iron uptake and the regulation of transferrin receptor and ferritin gene expression following inhibition of DNA synthesis. (Chitambar CR, Wereley JP) Cancer Res 1995 Oct 01;55(19):4361-6 PMID: 7671248 Scopus ID: 2-s2.0-0029024009 10/01/1995
• Induction of apoptosis by iron deprivation in human leukemic CCRF-CEM cells. (Haq RU, Wereley JP, Chitambar CR) Exp Hematol 1995 May;23(5):428-32 PMID: 7720813 Scopus ID: 2-s2.0-0029016627 05/01/1995
• Gallium nitrate delays the progression of microscopic disease in a human medulloblastoma murine model. (Whelan HT, Williams MB, Bajic DM, Flores RE, Schmidt MH, McAuliffe TL, Chitambar CR) Pediatr Neurol 1994 Jul;11(1):44-6 PMID: 7986292 Scopus ID: 2-s2.0-0027957135 07/01/1994
• Synergistic inhibition of T-lymphoblastic leukemic CCRF-CEM cell growth by gallium and recombinant human alpha-interferon through action on cellular iron uptake. (Chitambar CR, Wereley JP, Riaz-ul-Haq) Cancer Res 1994 Jun 15;54(12):3224-8 PMID: 8205543 Scopus ID: 2-s2.0-0028365792 06/15/1994
• Prevention of gallium toxicity by hyperhydration in treatment of medulloblastoma. (Whelan HT, Williams MB, Bajic DM, Segura AD, McAuliffe TL, Chitambar CR) Pediatr Neurol 1994 May;10(3):217-20 PMID: 8060423 Scopus ID: 2-s2.0-0028292326 05/01/1994
• Effect of T-cell depletion as graft-versus-host disease prophylaxis on engraftment, relapse, and disease-free survival in unrelated marrow transplantation for chronic myelogenous leukemia. (Drobyski WR, Ash RC, Casper JT, McAuliffe T, Horowitz MM, Lawton C, Keever C, Baxter-Lowe LA, Camitta B, Garbrecht F) Blood 1994 Apr 01;83(7):1980-7 PMID: 8142664 Scopus ID: 2-s2.0-0028179358 04/01/1994
• Modulation of transferrin receptor mRNA by transferrin-gallium in human myeloid HL60 and lymphoid CCRF-CEM leukaemic cells. (Ul-Haq R, Chitambar CR) Biochem J 1993 Sep 15;294 ( Pt 3)(Pt 3):873-7 PMID: 8379943 PMCID: PMC1134543 Scopus ID: 2-s2.0-0027437928 09/15/1993
• Effect of gallium on the tyrosyl radical of the iron-dependent M2 subunit of ribonucleotide reductase. (Narasimhan J, Antholine WE, Chitambar CR) Biochem Pharmacol 1992 Dec 15;44(12):2403-8 PMID: 1335254 Scopus ID: 2-s2.0-0026724397 12/15/1992
• Antineoplastic effects of gallium nitrate on human medulloblastoma in vivo. (Whelan HT, Schmidt MH, Anderson GS, Chan BK, Hunter K, Kubacki D, Segura AD, Chitambar CR) Pediatr Neurol 1992;8(5):323-7 PMID: 1418174 Scopus ID: 2-s2.0-0026441225 09/01/1992
• Regulatory effects of gallium on transferrin-independent iron uptake by human leukemic HL60 cells. (Chitambar CR, Sax D) Blood 1992 Jul 15;80(2):505-11 PMID: 1627803 Scopus ID: 2-s2.0-0026632436 07/15/1992
• Aspergillus and aspergillosis. (Rhodes JC, Jensen HE, Nilius AM, Chitambar CR, Farmer SG, Washburn RG, Steele PE, Amlung TW) J Med Vet Mycol 1992;30 Suppl 1:51-7 PMID: 1474459 01/01/1992
• Twice-daily tapering dexamethasone treatment during cranial radiation for newly diagnosed brain metastases. (Weissman DE, Janjan NA, Erickson B, Wilson FJ, Greenberg M, Ritch PS, Anderson T, Hansen RM, Chitambar CR, Lawton CA) J Neurooncol 1991 Dec;11(3):235-9 PMID: 1726656 Scopus ID: 2-s2.0-0026332525 12/01/1991
• Inhibition of ribonucleotide reductase by gallium in murine leukemic L1210 cells. (Chitambar CR, Narasimhan J, Guy J, Sem DS, O'Brien WJ) Cancer Res 1991 Nov 15;51(22):6199-201 PMID: 1933878 Scopus ID: 2-s2.0-0026356901 11/15/1991
• Shedding of transferrin receptor from rat reticulocytes during maturation in vitro: soluble transferrin receptor is derived from receptor shed in vesicles. (Chitambar CR, Loebel AL, Noble NA) Blood 1991 Nov 01;78(9):2444-50 PMID: 1932757 Scopus ID: 2-s2.0-0026038910 11/01/1991
• Allogeneic bone marrow transplantation for relapsed and refractory lymphoma using genotypically HLA-identical and alternative donors. (Lundberg JH, Hansen RM, Chitambar CR, Lawton CA, Gottlieb M, Anderson T, Ash RC) J Clin Oncol 1991 Oct;9(10):1848-59 PMID: 1919635 Scopus ID: 2-s2.0-0025994888 10/01/1991
• Inhibition of iron uptake in HL60 cells by 2-formylpyridine monothiosemicarbazonato Cu(II). (Narasimhan J, Antholine WE, Chitambar CR, Petering DH) Arch Biochem Biophys 1991 Sep;289(2):393-8 PMID: 1654860 Scopus ID: 2-s2.0-0026047967 09/01/1991
• Alteration of DNA synthesis in human brain tumor cells by gallium nitrate in vitro. (Whelan HT, Przybylski C, Chitambar CR) Pediatr Neurol 1991;7(5):352-4 PMID: 1764137 Scopus ID: 2-s2.0-0026319626 09/01/1991
• Evaluation of continuous infusion low-dose 5-azacytidine in the treatment of myelodysplastic syndromes. (Chitambar CR, Libnoch JA, Matthaeus WG, Ash RC, Ritch PS, Anderson T) Am J Hematol 1991 Jun;37(2):100-4 PMID: 1712548 Scopus ID: 2-s2.0-0025831445 06/01/1991
• Differential effects of gallium nitrate on proliferation of brain tumor cells in vitro. (Whelan HT, Przybylski C, Chitambar CR) Pediatr Neurol 1991;7(1):23-7 PMID: 2029289 Scopus ID: 2-s2.0-0026099279 01/01/1991
• Targeting iron-dependent DNA synthesis with gallium and transferrin-gallium. (Chitambar CR, Narasimhan J) Pathobiology 1991;59(1):3-10 PMID: 1645976 Scopus ID: 2-s2.0-0025972115 01/01/1991
• Interaction of gallium nitrate with fludarabine and iron chelators: effects on the proliferation of human leukemic HL60 cells. (Lundberg JH, Chitambar CR) Cancer Res 1990 Oct 15;50(20):6466-70 PMID: 1698536 Scopus ID: 2-s2.0-0025146833 10/15/1990
• Influence of cellular iron status on the release of soluble transferrin receptor from human promyelocytic leukemic HL60 cells. (Chitambar CR, Zivkovic-Gilgenbach Z) J Lab Clin Med 1990 Sep;116(3):345-53 PMID: 2401848 Scopus ID: 2-s2.0-0025073081 09/01/1990
• Development of drug resistance to gallium nitrate through modulation of cellular iron uptake. (Chitambar CR, Zivkovic-Gilgenbach Z, Narasimhan J, Antholine WE) Cancer Res 1990 Aug 01;50(15):4468-72 PMID: 2164439 Scopus ID: 2-s2.0-0025359548 08/01/1990
• Role of the acidic receptosome in the uptake and retention of 67Ga by human leukemic HL60 cells. (Chitambar CR, Zivkovic-Gilgenbach Z) Cancer Res 1990 Mar 01;50(5):1484-7 PMID: 2302713 Scopus ID: 2-s2.0-0025278214 03/01/1990
• Successful allogeneic transplantation of T-cell-depleted bone marrow from closely HLA-matched unrelated donors. (Ash RC, Casper JT, Chitambar CR, Hansen R, Bunin N, Truitt RL, Lawton C, Murray K, Hunter J, Baxter-Lowe LA) N Engl J Med 1990 Feb 22;322(8):485-94 PMID: 2300120 Scopus ID: 2-s2.0-11944271130 02/22/1990
• Release of soluble transferrin receptor from the surface of human leukemic HL60 cells. (Chitambar CR, Zivkovic Z) Blood 1989 Aug 01;74(2):602-8 PMID: 2752136 Scopus ID: 2-s2.0-0024328052 08/01/1989
• Effect of transferrin-gallium on leukemic cells. (Kaplinsky C) Blood 1989 Aug 01;74(2):887-8 PMID: 2752150 Scopus ID: 2-s2.0-0024374951 08/01/1989
• Transferrin receptor-mediated suppression of in vitro hematopoiesis by transferrin-gallium. (Chitambar CR, Craig A, Ash RC) Exp Hematol 1989 Jun;17(5):418-22 PMID: 2714421 Scopus ID: 2-s2.0-0024413371 06/01/1989
• Modulation of lymphocyte proliferation and immunoglobulin production by transferrin-gallium. (Chitambar CR, Seigneuret MC, Matthaeus WG, Lum LG) Cancer Res 1989 Mar 01;49(5):1125-9 PMID: 2537143 Scopus ID: 2-s2.0-0024504380 03/01/1989
• Inhibition of leukemic HL60 cell growth by transferrin-gallium: effects on ribonucleotide reductase and demonstration of drug synergy with hydroxyurea. (Chitambar CR, Matthaeus WG, Antholine WE, Graff K, O'Brien WJ) Blood 1988 Dec;72(6):1930-6 PMID: 3058232 Scopus ID: 2-s2.0-0024209928 12/01/1988
• Partially matched bone marrow transplantation in patients with myelodysplastic syndromes. (Bunin NJ, Casper JT, Chitambar C, Hunter J, Truitt R, Menitove J, Camitta BM, Ash R) J Clin Oncol 1988 Dec;6(12):1851-5 PMID: 3058877 Scopus ID: 2-s2.0-0024270190 12/01/1988
• Pityrosporum folliculitis after bone marrow transplantation. Clinical observations in five patients. (Bufill JA, Lum LG, Caya JG, Chitambar CR, Ritch PS, Anderson T, Ash RC) Ann Intern Med 1988 Apr;108(4):560-3 PMID: 3279893 Scopus ID: 2-s2.0-0023946560 04/01/1988
• Continuous 5-fluorouracil (5FU) infusion in carcinoma of the pancreas: a phase II study. (Hansen R, Quebbeman E, Ritch P, Chitambar C, Anderson T) Am J Med Sci 1988 Feb;295(2):91-3 PMID: 3344760 Scopus ID: 2-s2.0-0023880296 02/01/1988
• The effects of various transferrins on iron utilization by proliferating cells. (Seligman PA, Chitambar C, Vostrejs M, Moran PL) Ann N Y Acad Sci 1988;526:136-40 PMID: 3164599 Scopus ID: 2-s2.0-0023780513 01/01/1988
• Uptake of gallium-67 by human leukemic cells: demonstration of transferrin receptor-dependent and transferrin-independent mechanisms. (Chitambar CR, Zivkovic Z) Cancer Res 1987 Aug 01;47(15):3929-34 PMID: 3475168 Scopus ID: 2-s2.0-0023262160 08/01/1987
• Inhibition of hemoglobin production by transferrin-gallium. (Chitambar CR, Zivkovic Z) Blood 1987 Jan;69(1):144-9 PMID: 3790721 Scopus ID: 2-s2.0-0023103598 01/01/1987
• Effects of different transferrin forms on transferrin receptor expression, iron uptake, and cellular proliferation of human leukemic HL60 cells. Mechanisms responsible for the specific cytotoxicity of transferrin-gallium. (Chitambar CR, Seligman PA) J Clin Invest 1986 Dec;78(6):1538-46 PMID: 3465751 PMCID: PMC423914 Scopus ID: 2-s2.0-0022839492 12/01/1986
• Familial leukemia and aplastic anemia associated with monosomy 7. (Chitambar CR, Robinson WA, Glode LM) Am J Med 1983 Nov;75(5):756-62 PMID: 6638045 Scopus ID: 2-s2.0-0020564065 11/01/1983
• Regulation of transferrin receptor expression on human leukemic cells during proliferation and induction of differentiation. Effects of gallium and dimethylsulfoxide. (Chitambar CR, Massey EJ, Seligman PA) J Clin Invest 1983 Oct;72(4):1314-25 PMID: 6313760 PMCID: PMC370415 Scopus ID: 2-s2.0-0020509914 10/01/1983