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Mesh term Aryl Hydrocarbon Hydroxylases

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Cytochrome P-450 Enzyme System

Description

A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides.


Browse to child terms:
7-Alkoxycoumarin O-Dealkylase
Aniline Hydroxylase
Benzopyrene Hydroxylase
Cytochrome P-450 CYP1A1
Cytochrome P-450 CYP1A2
Cytochrome P-450 CYP1B1
Cytochrome P-450 CYP2B1
Cytochrome P-450 CYP2B6
Cytochrome P-450 CYP2C8
Cytochrome P-450 CYP2D6


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